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JPH04273865A |
PURPOSE: To provide the subject compound which has excellent heat stability and is useful for a bleaching agent, an oxidizing agent or a disinfectant. CONSTITUTION: This is a compound of formula I, which is exampled by 2-[1,1,3- trioxo-3...
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JPH0459313B2 |
Novel 1,5-benzothiazepine derivative of the formula:wherein R1 is hydrogen or lower alkanoyl and each of R2 and R3 is lower alkyl, and a pharmaceutically acceptable acid addition salt thereof are disclosed.There is also disclosed a proce...
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JPH0458471B2 |
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JPH04244072A |
PURPOSE: To easily obtain at a low cost in high yield the title compound useful as a photofading preventive or an intermediate therefor by reaction between a diol and an aniline derivative in the presence of a metallic catalyst. CONSTITU...
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JPH04221376A |
PURPOSE: To industrially effectively prepare the subject derivative which is effectively used in the preparation of diltiazem, by cyclizing an ester of 2- hydroxy-3-(4-R3-phenyl)-3-(2-aminoarylthio)propionic acid in the presence of a bas...
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JPH04217964A |
PURPOSE: To provide new aralkylsulfonyl urea effectively used as a herbicide, particularly for selectively controlling the diocotyledonous weeds in monocotyledonous crops. CONSTITUTION: This compound is represented by formula I [(n) is 2...
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JPH04217961A |
PURPOSE: To provide new compounds which inhibit the angiotensinogen-cutting action of the natural proteolytic enzyme, renin. CONSTITUTION: This compound is represented by formula I [A is H, Het (Het is 5-7 membered monocyclic ring having...
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JPH04211071A |
PURPOSE: To obtain a new polycyclic compound useful as an antihistaminic agent, a hypnotic agent, a sedative, an analgesic agent, a hyperkinetic agent for gastrointestinal tract movement, etc., excellent in selectivity with hardly any si...
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JPH04197837A |
PURPOSE: To detect events at high speed by providing a transient detection circuit and an event processor in addition to a control and arithmetic processor, and detecting the occurence of an event independently of the period of arithmeti...
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JPH04187680A |
NEW MATERIAL:Compounds of formula I [R is H, alkyl, aralkyl; R2 is lower alkyl; X, Y are O, CH2, NCO2R3 (R3 is lower alkyl); n is 0, 1] and II (W is H, group of formula III). USE: An intermediate capable of being converted into medicines...
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JPH0427213B2 |
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JPH0425266B2 |
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JPH04128276A |
NEW MATERIAL:The compound of formula I [Z is A, group of formula II, CR2=N, etc., (A is O, S, SO, etc.; R2 and R3 are H, OH, halogen, etc.; R2 and R3 may be independently 3-6C cycloalkyl); R1 is H, 1-5C alkyl, alkanoyl or benzyl; (m) is ...
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JPH0424352B2 |
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JPH0421668B2 |
Compounds of the general formula: (wherein R<1> is hydrogen or C2-4 alkanoyl, each of R<2> and R<3> is C1-4 alkyl, and each of R<4> and R<5> is C1-4 alkyl, C1-4 alkoxy or halogen) and their acid addition salts are hypotensive agents and/...
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JPH0421667B2 |
Novel 1,5-benzothiazepine derivatives of the formula: wherein R<1> is hydrogen or lower alkanoyl, each of R<2> and R<3> is lower alkyl, and either one of R<4> and R<5> is fluorine and the other one is hydrogen, and a pharmaceutically acc...
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JPH0454174A |
PURPOSE: To obtain stereoselectively the title compound useful as an intermedi ate for synthesizing the therapeutic agents for stenocardia by reaction between a trans-modification of cinnamic ester and an o-aminothiophenol under specifie...
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JPH045040B2 |
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JPH045027B2 |
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JPH0378858B2 |
The invention concerns 5-[(3-chloro-6-methyl-5,5-dioxo-6,11-dihydro-dibenzo (c,f) (1,2) thiazepin-11-yl)-amino] pentanoic acid. Medicament.
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JPH03275677A |
NEW MATERIAL:A compound expressed by formula I [R1 is 1-5C (allyl group substituted) alkyl; R2 is H, 1-5C alkyl or protected 1-5C hydroxyalkyl; R3 and R4 are R2 or 1-5C (allyl group substituted) alkoxy; A is 2-5C (substituted) alkylene; ...
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JPH0376307B2 |
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JPH0376289B2 |
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JPH0376290B2 |
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JPH03271269A |
PURPOSE: To economically prepare the subject compound which can be effectively used as an intermediate for synthesizing a calcium channel blocking cardiovascular agent in high yield by treating a racemic threo mixture of a specific with ...
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JPH0374662B2 |
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JPH0374661B2 |
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JPH0374660B2 |
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JPH0374659B2 |
Novel 1,5-benzothiazepine derivatives of the formula:wherein R1 is hydrogen or lower alkyl, R2 is hydrogen, lower alkanoyl or benzyl, R3 is hydrogen or lower alkyl and either one of R4 and R5 is hydrogen and the other is chlorine, or a p...
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JPH0374223B2 |
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JPH0374224B2 |
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JPH0374221B2 |
Novel benzothiazepine derivatives of the formula wherein R<1> and R<2> are each lower alkyl, R<3> is hydrogen, lower alkyl or hydroxy-lower alkyl, R<4> is hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio or nitro, and A is l...
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JPH0374222B2 |
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JPH03264584A |
NEW MATERIAL:A compound expressed by formula I {R1 and R2 are H or alkyl; R3 is H, alkyl or (substituted) phenylalkyl; R4 and R5 are H, halogen, alkyl, (acyl)amino, OH, nitro, etc.; X is O or NH; R6 is formula II (m is 0 or 1), formula I...
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JPH03264570A |
NEW MATERIAL:A compound shown by formula I [R1 and R2 are H or alkyl; R3 is R1, R2 or (substituted)phenylalkyl; R4 and R5 are R1, R2, halogen, alkoxy, amino, OH, nitro, etc.; X is O or NH; R6 is group shown by formula II (m is 0 or 1), g...
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JPH0373546B2 |
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JPH0373545B2 |
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JPH0372623B2 |
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JPH0372062B2 |
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JPH03254698A |
PURPOSE: To carry out a sensitive quantitative analysis of a specified component by using a peroxidase-marked substance as the specified component of an analytical object, using H2O2, an aromatic primary amine and a specified nitrogen-co...
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JPH03251574A |
NEW MATERIAL:A compound of formula I [R1 is 1-5C alkyl or 1-5C allylsubstituted alkoxy; R2 is H, 1-5C alkyl, protected 1-5C hydroxyalkyl or protected carboxyl; R3 is R1, H, protected 1-5C hydroxyalkyl or 1-5C alkoxy; A is (substituted) 2...
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JPH0366311B2 |
This invention relates to a compound of the formula (I) wherein R1, R2, R3, and R4, which may be the same or different, each represent a hydrogen or halogen atom or an alkyl or alkoxy group of from 1 to 6 carbon atoms; R5 and R6, which m...
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JPH03220184A |
NEW MATERIAL:The compound of formula I (R1 and R2 are H, alkyl, aralkyl or bonded together with adjacent N to form a heterocyclic group; R3 is H or 1-3 halogens). EXAMPLE: 3(R)-[3-cyclopentanone-1(R)-carboxamido]-4-oxo-2(S)-phenyl-2
,3,4...
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JPH0354939B2 |
PROCESS FOR THE PREPARATION OF /2S,3S/-3-ACETOXY-5- -/N,N-DIMETHYLAMINOETHYL/-2-/4-METHOXYPHENYL/-2,3- -DIHYDRO-1,5-BENZOTHIAZEPIN-4/5H/-ONE A b s t r a c t The invention relates to a new process for the preparation of /2S,3S/-3-acetoxy-...
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JPH0354663B2 |
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JPH03170433A |
PURPOSE: To inhibit the metastasis of cancer by administering a benzothiazepine synergist to an organism having the cancer. CONSTITUTION: This method for treating the metastasis of cancer comprises administering a compound of the formula...
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JPH03133970A |
NEW MATERIAL: Benzothiazepine derivative of formula I (where R1=H, C2-6 alkanoyl; R2=H, C1-6 alkyl; n=0-3; R3 = phenyl having 1 to 3 pieces of substituents, which is selected from among halogen, trifluoromethyl, methyl, C1-6 alkoxy, alky...
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JPH0333713B2 |
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JPH0333714B2 |
NEW MATERIAL:A compound of formula I (n is 1-5). EXAMPLE:2-(4-Methoxyphenyl)-3-acetoxy-5-(2-dimethylaminoethy
l)-1,5-ben zothiazepin-4(5H)-one. USE:A drug having coronary-vasodilating, antiarrhythmic, blood platelet coagulation-inhibitin...
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JPH0356471A |
PURPOSE: To obtain 4-methoxyphenylglycidic ester stereospeciffically in a high yield by reacting a novel diastereoisomer of chlorohydrin corresponding to the objective compd. or a mixture of diastereoisomers of chlorohydrin with a specif...
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