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Matches 1 - 50 out of 5,910

Document Document Title
WO/2018/183699A1
Methods and materials for providing corrosion protection for atomically thin materials are described. In some embodiments, an atomically thin material may have a coating that includes one or more alkyl amine species. The coating may cove...  
WO/2018/178384A1
The invention relates to a compound of formula (I): A-B-D-E (I) or a pharmaceutically acceptable salt, solvate or polymorph thereof, including all tautomers and stereoisomers thereof, wherein: A is selected from monocyclic and bicyclic h...  
WO/2018/178057A1
A method of improving plant safety and/or reducing phytotoxicity and/or reducing plant necrosis whilst combating, preventing or controlling phytopathogenic diseases, which comprises applying to a phytopathogen, to the locus of a phytopat...  
WO/2018/170275A1
The present invention provides a compound having the structure:, or a pharmaceutically acceptable salt or ester thereof, and a method of treating a subject afflicted with a pain, a depressive disorder, a mood disorder, an anxiety disorde...  
WO/2018/160618A1
Substituted hydroquinones, 1,4-quinones, catechols, 1,2-quinones, anthraquinones, and anthrahydroquinones are disclosed herein. The substituted hydroquinones and catechols have the formula: while the substituted 1,4-quinones or 1,2-have ...  
WO/2018/157813A1
The present invention relates to a series of tricyclic compounds and the use thereof as receptor agonists of sphingosine 1-phosphate subtype 1 (S1P1), and in particular relates to compounds as shown in formula (I) or pharmaceutically acc...  
WO/2018/159834A1
Provided are a donor-acceptor type compound having a novel structure and an application of the donor-acceptor type compound. This enamine compound is represented by general formula (1) (in the formula: R1 represents an electron-accepting...  
WO/2018/140599A1
Compounds having activity as inhibitors of G12C mutant KRAS protein are provided. The compounds have the following structure (I) or a pharmaceutically acceptable salt, stereoisomer or prodrug thereof, wherein B, Z, Ra, Rb, Rc, R1, L, L1 ...  
WO/2018/131690A1
[Problem] To provide a novel agrochemical, especially a novel herbicide. [Solution] A ketone or oxime compound represented by formula (1), and a herbicide which contains this compound. (In the formula, B represents B-1 or B-2; Q represen...  
WO/2018/122325A1
The present invention pertains to a system of collaborative modifiers that are assembled into a multi molecule complex in vivo within a cell using bioorthogonal chemical reactions. The system of the invention is composed of multiple bind...  
WO/2018/116073A1
24859-P4PCT ABSTRACT 1, 2, 3-Thiadiazole compounds and their use as crop protecting agent The present invention relates to 1,2,3-thiadiazole compounds of the formula (I), wherein R1, R2, T and Z have the meanings as defined in descriptio...  
WO/2018/116107A1
Provided are IDO inhibitor compounds of Formula (I) and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases ...  
WO/2018/111619A1
Pharmaceutical compositions for treating or mitigating glaucoma are described, the compositions comprising several separate components for an improved effect. Methods for fabricating the compositions and using them are also described.  
WO/2018/108791A1
The present application relates to thiadiazole compounds of formula (I), in which A, B, E, and Q have the meanings provided in the specification, compositions containing such compounds, their use for controlling animal pests including ar...  
WO/2018/102921A1
Herein presented are gold nanoparticles (AuNPs) used for the transport of medications to mucous membranes. The AuNPs are ultra-stable in that they withstand freeze-drying and heating treatments without noticeable change in their structur...  
WO/2018/106284A1
This invention is directed to benzenesulfonamide compounds, as stereoisomers, enantiomers, tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment of diseases or condit...  
WO/2018/093694A1
Disclosed are compounds of Formula A, or a salt thereof: Formula (A), wherein: Het, Q and R1A to R4A are defined herein, which compounds have properties for blocking Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also ...  
WO/2018/089402A1
There are described RORγ Gamma modulators of the formula (I), (I) or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutic...  
WO/2018/081384A1
The present disclosure relates to compounds of formula I which inhibit NaV1.7, and include pharmaceutically acceptable salts, compositions comprising such compounds, and methods using and making such compounds and compositions. (I)  
WO/2018/072602A1
The invention provides a compound of formula I: or a pharmaceutically acceptable salt thereof, wherein the variables X, Y1-Y5, R1, R2, R3, R4, and Het have the meaning as described herein, and compositions containing such compounds and m...  
WO/2018/071327A1
This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions con...  
WO/2018/064119A1
Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.  
WO/2018/062978A1
The present invention relates to a novel heteroaryl compound, an enantiomer, a diastereomer or a pharmaceutically acceptable salt thereof, and an antiviral composition comprising the same as an active ingredient. The novel compounds repr...  
WO/2018/051252A2
An object of the present invention is to provide an amide compound or a salt thereof that controls a mite. The present invention provides an amide compound represented by Formula (1) : or a salt thereof, wherein R1 represents C1-6 alkyl ...  
WO/2018/051255A1
The present invention relates to cyclic substituted 1,3,4-oxadiazole and thiadiazole compounds of formula (I) and their use to inhibit the programmed cell death 1 (PD1) signaling pathway and/or for treatment of disorders by inhibiting an...  
WO/2018/051252A3
An object of the present invention is to provide an amide compound or a salt thereof that controls a mite. The present invention provides an amide compound represented by Formula (1) : or a salt thereof, wherein R1 represents C1-6 alkyl ...  
WO/2018/051254A1
The present invention relates to cyclic substituted-1,2,4-oxadiazole compounds of formula (I) and their use to inhibit the programmed cell death 1 (PD1) signalling pathway and/or for treatment of disorders by inhibiting an immunosuppress...  
WO/2018/041768A1
The invention relates to novel organic semiconducting (OSC) compounds containing one or more 1,3-dithiolo[5,6-f]benzo-2,1,3-thiadiazole ("DTBTz") or 1,3-dithiolo[6,7-g]quinoxaline ("DTQ") units or derivatives thereof, to methods for thei...  
WO/2018/033654A1
The present invention relates to new hole-transporting materials (HTMs) and optoelectronic and/or electrochemical devices comprising the new hole-transporting materials. In some aspects, the HTMs comprise a core based on thienothiophene,...  
WO/2018/029150A1
The invention relates to compounds acting as agonists of G-protein coupled receptor 120 (GPR120) and/or 40 (GPR40), and having formula (I). Said compounds are useful in the treatment of diseases or disorders modulated by GPR120 and/or GP...  
WO/2018/028557A1
The present invention relates to a series of tricyclic compounds and the use thereof as receptor agonists of 1-phosphate sphingosine 1 subtype (S1P1), and in particular to the compounds shown in formula (I), and tautomers or pharmaceutic...  
WO/2018/011747A1
The present invention provides compounds which are modulators of RORγ and their use for the treatment of diseases or conditions mediated by RORγ. Further, the present invention relates to processes of preparing such compounds, their ta...  
WO/2017/219083A1
The present invention relates to novel compounds which active HIV expression in latently infected cells. More particularly, the invention relates to pharmaceutical compositions comprising the novel compounds and their use in activating H...  
WO/2017/202376A1
A sulfamide compound and a use thereof in preparing pain killers, which specifically relates to compounds as shown in formula (I) and formula (II), tautomers thereof or pharmaceutically acceptable salts thereof.  
WO/2017/167315A1
Provided are an anthracenyl organic dye and a preparation method therefor. The organic dye has the structure shown in formula (I) or formula (II), wherein Ra, Rb and R2-1 – R2-4 are defined in the present document. The organic dye is p...  
WO/2017/165256A1
The present disclosure relates to compounds of formula (I) that are useful as modulators of α7 nAChR, compositions comprising such compounds, and the use of such compounds for preventing, treating, or ameliorating disease, particularly ...  
WO/2017/160922A1
Disclosed herein are compounds of Formula (I), methods of synthesizing compounds of Formula (I), and methods of using compounds of Formula (I) as an analgesic.  
WO/2017/129121A1
The present invention relates to 1,2,3,-thiadiazole oxime ether strobilurin derivatives having a general chemical structure as shown in IV. Provided in the present invention are thiadiazole oxime ether strobilurin derivatives, a preparat...  
WO/2017/122209A2
Disclosed herein are compounds capable of inhibiting dimerization of NF-κB, for example, p65-p65 homodimerization and/or p50-p65 heterodimerization, the compounds being represented by formula I: X-L2-L1-L'2-Y Formula I wherein X, Y, L1,...  
WO/2017/112947A1
Provided herein are compounds that activate CFTR and methods for treating constipation, dry eye disorders or other diseases and disorders.  
WO/2017/106505A1
Provided herein are compounds that can bind GAS5 long non-coding RNA, compositions thereof, and uses thereof.  
WO/2017/106226A1
Disclosed are compounds of Formula A, or a salt thereof: Formula (A) wherein R1, R2, and E are defined herein, which compounds have properties for inhibiting Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also describe...  
WO/2017/098421A1
The invention is directed to substituted benzothiadiazine derivatives. Specifically, the invention is directed to compounds according to Formula (I):wherein R, R1, R2, R3, R4 and R5 are as defined herein. The compounds of the invention a...  
WO/2017/079678A1
The invention relates to a novel variable hydrate crystalline form of 1-(5-(4-chloro-3,5-dimethoxyphenyl)furan-2-yl)-2-ethoxy-2-(4 -(5-methyl-1,3,4-thiadiazol-2-yl)phenyl)ethanone, methods for the preparation thereof, pharmaceutical comp...  
WO/2017/059303A1
Provided herein are vinylogous thioester compounds and methods for using the compounds.  
WO/2017/051353A1
Provided are compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of HIV; including the prevention of the p...  
WO/2017/051354A1
Provided are compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of HIV; including the prevention of the p...  
WO/2017/049158A1
The present invention provides a compound having the structure of the instant invention or a pharmaceutically acceptable salt or ester thereof, methods of preparing the same, and methods of treating a subject with compounds of the instan...  
WO/2017/042188A1
The present invention relates to a highly convergent method for the synthesis and purification of ceftolozane and intermediates starting from 7-aminocephaiosporanic acid (7- ACA).  
WO/2017/030122A1
This lubricant comprises an ionic liquid that includes a conjugate base and a conjugate acid, the conjugate acid having a group that includes a linear hydrocarbon group with at least six carbon atoms, pKa in acetonitrile of the acid whic...  

Matches 1 - 50 out of 5,910