Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 1 - 50 out of 2,818

Document Document Title
WO/2020/185420A1
Provided herein are integrated methods and systems for the production of acrylamide and acrylonitrile compounds and other compounds from at least beta-lactones and/or beta-hydroxy amides.  
WO/2020/177748A1
The present invention relates to the technical field of medicines, and specifically disclosed are a quaternized modified taxane derivative, a pharmaceutical composition, and a synthetic pathway and use thereof. The taxane derivative is p...  
WO/2020/156307A1
The present invention relates to the technical field of pharmacy, relates to a lymphatic mediated transport-based triglyceride prodrug, and specifically relates to a triglyceride prodrug of different joining chains in a lymphatic mediate...  
WO/2020/144297A1
The present invention concerns nanoemulsions encapsulating a prodrug and bearing a targeting ligand, said nanoemulsion being formed by a natural oil and/or a synthetic oil and an amphiphilic surfactant, the methods for preparing these na...  
WO/2020/135427A1
The present invention relates to a monomer compound represented by formula (I), wherein each variable is as defined in the description. The described monomer is quickly synthesized at a high yield by means of a click chemistry reaction b...  
WO/2020/139001A1
The present invention provides a novel aryl-substituted aminomethyloxetenyl amino alcohol derivative or a pharmaceutically acceptable salt thereof. More specifically, the derivative has an effect of promoting ATP production and as such, ...  
WO/2020/107078A1
Provided herein is a dendrimer comprising: i) a core unit (C); and ii) building units (BU), wherein the core unit is covalently attached to at least two building units; the dendrimer having from two to six generations of building units; ...  
WO/2020/104822A1
The present invention relates to a compound of formula (Ia), or a pharmaceutically acceptable salt or hydrate thereof, wherein: the group X-Y is -NHSO2- or -SO2NH-; R1 is H or alkyl; R2 is selected from COOH and a tetrazolyl group; R3 is...  
WO/2020/097739A1
Provided herein are nanoparticles including self-assembled cellular components derived from a homogenized plant tissue. Also provided are food powders and other related compositions. Methods for preparing such nanoparticles and food powd...  
WO/2020/078421A1
A monomer compound of formula (I) and a method for preparing the monomer. Each variable is as defined in the description. According to the present monomer, by means of a click chemistry reaction between thiol and olefin, a perfluorinated...  
WO/2020/078423A1
A monomeric compound of formula (I), wherein variables are as defined in the specification. The monomer is synthesized in high yield and fast by means of click chemistry reaction between mercaptan and alkene, and a basically perfluorinat...  
WO/2020/078422A1
Provided is the monomer compound of formula (I), the variables thereof being as defined in the description. The monomer is synthesized at high yield and quickly by means of a click chemistry reaction between a thiol and an olefin; furthe...  
WO/2020/039092A3
The present invention comprises novel aromatic molecules, which can be used in the treatment of pathological conditions, such as cancer, skin diseases, muscle disorders, and immune system-related disorders such as disorders of the haemat...  
WO/2020/039088A3
The present invention comprises novel aromatic molecules, which can be used in the treatment of pathological conditions, such as cancer, skin diseases, muscle disorders, and immune system-related disorders such as disorders of the haemat...  
WO/2020/039092A2
The present invention comprises novel aromatic molecules, which can be used in the treatment of pathological conditions, such as cancer, skin diseases, muscle disorders, and immune system-related disorders such as disorders of the haemat...  
WO/2020/039088A2
The present invention comprises novel aromatic molecules, which can be used in the treatment of pathological conditions, such as cancer, skin diseases, muscle disorders, and immune system-related disorders such as disorders of the haemat...  
WO/2020/033248A1
The present invention is directed to processes for producing beta-lactone and beta-lactone derivatives using heterogenous catalysts. In preferred embodiments of the present invention, the processes comprise: passing a feed stream compris...  
WO/2020/027150A1
A compound represented by general formula (I) (wherein each symbol is as defined in the description) or a salt thereof has a potent neural protecting and/or repairing effect and, therefore, is usable as a therapeutic agent for neurologic...  
WO/2020/014750A1
Provided herein are dendrimers comprising: a core unit, five generations of building units which are lysine residues or analogues thereof, first terminal groups comprising a cabazitazel residue covalently attached to a diglycolyl linker ...  
WO/2020/016427A1
The present invention relates to compounds that are inhibitors of hepatitis B virus (HBV). Compounds of this invention are useful alone or in combination with other agents for treating, ameliorating, preventing or curing HBV infection an...  
WO/2020/011062A1
Provided are an epoxy modified acrylic resin and a preparation method therefor, and an energy-curable composition containing epoxy modified acrylic resin and application. A branched chain of at least one repeat unit in the acrylic resin ...  
WO/2020/005935A1
This invention provides compounds that modulate glucose uptake activity and cellular transport/uptake of glucose, and particularly GLUTS3, but also including but not limited to GLUT1-14 (SLC2A1-SLC2A14). Compounds of the invention are us...  
WO/2019/242691A1
Provided are a paclitaxel-lipid-polysaccharide dual-type conjugate related to general formula I, a preparation method therefor, a use thereof, and a pharmaceutical composition comprising same. The present invention also relates to a seri...  
WO/2019/228994A1
This invention relates to oleic acid derivative comprising a hydrophobic part C17H33 linked to a particular polar head part "A", especially for use as a medicament, for instance, for the treatment of a disorder caused by the GPR120 recep...  
WO/2019/226490A1
Provided is a compound of Formula (I), wherein the variable groups are defined herein.  
WO/2019/221925A1
Provided herein are integrated systems and processes for more efficient use of raw materials in chemical synthesis of ammonia, urea and copolymers. The systems and processes may include nutrient fermentation, carbonylation of syngas deri...  
WO/2019/206156A1
The present invention provides pharmaceutically acceptable salts of a benzodicycloalkane derivative, a polymorphic substance thereof, and an application thereof. Specifically, the present invention provides a benzodicycloalkane derivativ...  
WO/2019/170092A1
The present invention provides a ketone carbonyl-containing hydrophobic antitumor drug and a conjugate thereof as well as a nano preparation containing the conjugate, a preparation method therefor, and an application thereof. The conjuga...  
WO/2019/148282A1
The present disclosure concerns methods and formulations for delivery of hydrophobic agents (such as ubiquinone or poorly soluble drugs) for therapeutic and bioanalytical use. It further concerns use of lipopeptides (e.g. caspofungin) or...  
WO/2019/143220A1
The present invention relates to a transition metal-based heterogeneous carbonylation reaction catalyst, which has excellent catalyst activity and selectivity in a carbonylation reaction by polymerizing transition metal-based heterogeneo...  
WO/2019/124345A1
The present invention addresses the problem of providing: a polymerizable liquid crystal composition that satisfies the demand for the high-speed response, low-voltage drive, high contrast, long-term reliability, and the like that have h...  
WO/2019/110427A1
Compounds of the formula (I) wherein the subsitiuents are as defined in claim 1. Furthermore, the present invention relates to agrochemical compositions which comprise compounds of formula (I), to preparation of these compositions, and t...  
WO/2019/104030A1
Provided are compounds of Formula I, or pharmaceutically acceptable salts thereof, and methods for their use as Nrf2 activators and for their production.  
WO/2019/099314A1
Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof. Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder...  
WO/2019/080466A1
Disclosed are a 3-arylbenzofuranone propanamide compound, a composition composed of same, and a preparation method thereof. The compound of the present invention can be used as a stabilizer in various materials, for example, in organic m...  
WO/2019/074748A1
Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: (Formula (I)). Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated dise...  
WO/2019/070981A1
The present invention is directed to processes for producing isocyanates and isocyanate derivatives from epoxide and carbon monoxide reagents. In preferred embodiments, the processes include a step for providing carbonylation of an epoxi...  
WO/2019/061299A1
Provided is a one-step amination reaction for producing an aminomethyl substituted heterocycloalkane, notably (tetrahydrofuran-2, 5-diyl) dimethanamine.  
WO/2019/050649A1
The present invention is directed to catalysts and processes for catalyzing two or more chemical reactions with a multifunctional catalyst in a reaction vessel. The processes include steps for introducing one or more reagents to a reacti...  
WO/2019/051184A1
Provided herein are acrylamide and acrylonitrile compounds and other compounds that may be produced from hydroxy amides and/or lactones. Provided herein are methods and systems to produce such compounds.  
WO/2019/033982A1
Disclosed is an oxetane compound used in a cation photocurable system. The oxetane compound is formed by a nucleophilic substitution reaction of a compound containing at least one hydroxyl and at least one oxetane group with a halohydroc...  
WO/2019/019924A1
Disclosed is a new oxetane monomer compound, which has a structure as shown in general formula (I) or is an ester of a compound of general formula (I). The monomer compound has a high reaction activity. After being applied to a cationic ...  
WO/2019/009412A1
The present invention addresses the problem of providing a novel compound having high LSD1 inhibitory activity, high selectivity for LSD1 inhibition, and/or having useful therapeutic effects for various diseases. One embodiment of the pr...  
WO/2019/008156A1
The present invention provides novel compounds of formula (I) that are useful as inhibitors of the PD-1/PD-L1 protein/protein interaction. The compounds may be used in the treatment of cancer, infectious diseases and neurodegenerative di...  
WO/2018/225093A1
The invention is directed to substituted bridged cycloalkane derivatives. Specifically, the invention is directed to compounds according to Formula (IIIQ): wherein X6', a, b, C8', D8', L82', L83', R81', R82', R83', R84', R85', R86', z82'...  
WO/2018/225018A1
The present invention relates to novel heterocyclic compounds of the general formula (I) their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, enantiomers, diastereomers and polymorphs. The invention also relates...  
WO/2018/223227A1
There are provided compositions and methods for prevention or treatment of atherosclerosis and related disorders. More specifically, there are provided desmocollin 1 inhibitor compounds and pharmaceutical compositions thereof for use in ...  
WO/2018/195439A3
Provided herein, inter alia, are methods and compounds for modulating K-Ras treating cancer.  
WO/2018/200471A1
The present invention is directed to reactor systems and processes for producing organic acids through thermolysis of polylactones. In preferred embodiments, the reactor systems and processes are capable of introducing at least one epoxi...  
WO/2018/195439A2
Provided herein, inter alia, are methods and compounds for modulating K-Ras treating cancer.  

Matches 1 - 50 out of 2,818