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Matches 551 - 600 out of 28,400

Document Document Title
WO/2012/131410A1
The invention relates to a novel process for preparation of drohedarone of formula (I) and pharmaceutically acceptable salts thereof characterized in that a compound of formula (II) is reacted in the presence of a reductive agent with bu...  
WO/2012/130299A1
Novel compounds of the formula (I) wherein R1, R2, D, A, B and X have the meanings defined herein, pharmaceutical compositions comprising them as active ingredient, as well as their use in medicine, in particular as peptidase inhibitors,...  
WO/2012/131028A1
The invention relates to a carbonylation process for the preparation of a compound of formula (I) XOOC-(CH2)4-COOY (I) wherein X and Y can independently represent H and/or alkyl, said carbonylation process comprising reacting: (a) a comp...  
WO/2012/134258A1
The use or methods of use of extracts comprising one or more special clerodane compounds against inflammatory (including allergic) diseases or conditions, as well as novel compounds of this type, said clerodane derivatives for use agains...  
WO/2012/133861A1
An amide compound represented by the formula (I): [wherein, R1, R2, R3, R4, R5, R6, R7, R8, X, W, r, n and Y are as defined in the description] has an excellent control effect on harmful arthropods.  
WO/2012/133653A1
This charge transport material, which comprises a compound represented by the formula, has a high efficiency and drive durability after high-temperature storage, and resists the occurrence of dark spots (X101 represents a sulfur atom or ...  
WO/2012/133644A1
An organic electroluminescent element, which comprises a substrate, a pair of electrodes including a positive electrode and a negative electrode that are arranged on the substrate, and an organic layer that is arranged between the electr...  
WO/2012/131063A1
An oligo-or polyimide comprising one or two residue(s)of an anhydride based acetylenic end-capper, at least one EBPA residue, at least oneresidueof anaromatic di- amine,and optionally at least one residue of an aromatic non-acetylenic di...  
WO/2012/131409A1
The invention relates to a novel process for preparation of dronedarone (I) and pharmaceutically acceptable salts thereof where the compound of formula (II) or salt thereof is reacted with a compound of formula L-(CH2)3-CH3 (III), where ...  
WO/2012/131408A1
The invention relates to a novel process for preparation of N-[2-n-butyl-3-[4-[3-(di-n- butylamino)-propoxy]-benzoyl]-benzofuran÷5-yl]methanesulfon amide (I) and pharmaceutical acceptable salts thereof, where a salt of (5-amino-2-butyl-...  
WO/2012/131027A1
The invention relates to a carbonylation process for the preparation of an alkanoic acid ester comprising reacting: (a) an alkene; (b) a source of Pd; (c) a bidentate phosphine ligand of formula I; R1R2P - R3 - R - R4 - PR5R6 (I) wherein...  
WO/2012/129452A8
This invention discloses a series of novel propynoic acid carbamoyl methyl-amides (PACMAs), methods for synthesizing the PACMAs and pharmaceutical compositions containing the PACMAs. These novel compounds and compositions show cytotoxici...  
WO/2012/129452A3
This invention discloses a series of novel propynoic acid carbamoyl methyl-amides (PACMAs), methods for synthesizing the PACMAs and pharmaceutical compositions containing the PACMAs. These novel compounds and compositions show cytotoxici...  
WO/2012/129473A1
The present invention provides complexes of gallium with a ligand, methods of making the complexes, methods of using the complexes and pharmaceutical gallium compositions comprising the complexes, in particular those compositions suitabl...  
WO/2012/127173A1
The invention relates to a process for synthesizing benzofuran derivatives, in particular dronedarone of formula (D), comprising a step of Friedel-Crafts acylation starting from a sulfonamido-benzofuran ester intermediate.  
WO/2012/129452A2
This invention discloses a series of novel propynoic acid carbamoyl methyl-amides (PACMAs), methods for synthesizing the PACMAs and pharmaceutical compositions containing the PACMAs. These novel compounds and compositions show cytotoxici...  
WO/2012/127174A1
The invention relates to a method for synthesizing benzofuran derivatives, in particular the dronedarone of formula (D), including carrying out a Fries rearrangement reaction using a sulfonamido-benzofuran ester intermediate.  
WO/2012/128510A3
The present invention relates to a method for preparing a furfuranol-based compound and a 2-furancarboxylic acid-based compound by reacting a furfural-based compound with the hydroxide of an alkali metal or alkaline earth metal using an ...  
WO/2012/128510A2
The present invention relates to a method for preparing a furfuranol-based compound and a 2-furancarboxylic acid-based compound by reacting a furfural-based compound with the hydroxide of an alkali metal or alkaline earth metal using an ...  
WO/2012/123957A1
This invention relates to oligopeptides having general formula (I). The invention also relates to the process of preparation thereof, wherein the said compounds are selective anti-cancer agents over a panel of human cancer cell lines. Fu...  
WO/2012/124696A1
[Problem] To provide a compound which is useful as an active ingredient of a pharmaceutical composition, especially of a pharmaceutical composition for the prophylaxis and/or treatment of VAP-1 associated diseases. [Solution] As a result...  
WO/2012/121248A1
A method for highly enantio-selectively producing an optically active spirolactone compound using a iodoarene derivative which can be easily synthesized and scarcely racemized. From 2,6-dihydroxyiodoarene, a flexibly designable hypervale...  
WO/2012/119927A1
The invention relates to a method for producing primary amines comprising at least one functional group of formula (-CH2-NH2), by alcohol amination of educts which comprise at least one functional group of formula (–CH2-OH), using ammo...  
WO/2012/120544A2
The present invention provides a process for preparing compound of formula (I),  
WO/2012/120544A3
The present invention provides a process for preparing compound of formula (I),  
WO/2012/119265A1
The present invention discloses esters of 4,9-dihydroxy-naphtho[2,3-b]furans and methods of making and using the same. The present invention also discloses conversion of the esters into therapeutically active 4,9-dihydroxy-naphtho[2,3-b]...  
WO/2012/119928A1
The invention relates to a method for producing alkanol amines which comprise a primary amino group (-NH2) and a hydroxyl group (-OH), by alcohol amination of diols comprising two hydroxyl groups (-OH), using ammonia, and elimination of ...  
WO/2012/116977A1
The invention relates to a process for the preparation of 3-methylene-γ-butyrolactone (Z), the process comprising a hydroformylation step wherein 1,4-butene-diol (X) or its ester derivative cis-1,4-diacetoxy butene (Y) is subjected to H...  
WO/2012/117015A1
A process for preparing sodium salts or potassium salts of 4-hydroxy-2-oxo-2,5-dihydrofuran-3-carboxylate, comprising the reaction of a malonic ester with potassium hydroxide to give the corresponding malonic ester potassium salt of the ...  
WO/2012/118286A1
The present invention relates to a novel compound isolated from Kaempferia pandurata Roxb and the use thereof as an antiviral agent. The compound isolated from Kaempferia pandurata Roxb shows the ability to inhibit highly pathogenic viru...  
WO/2012/115578A1
The present invention concerns the synthesis of substantially anomerically pure 2,3-dideoxy-3- fluoro-5-0-(4-phenylbenzoyl)-a-D-erythropentofuranosyl chloride from an α/β-mixture of the corresponding methyl glycoside. The method of the...  
WO/2012/113609A1
The invention relates to the use of heptyl esters of furan dicarboxylic acid as softeners.  
WO/2012/115129A1
Provided are: the polymeric liquid crystal compound represented by formula [1]; a polymeric liquid crystal composition containing same; a polymer, coating film, and oriented film obtained using same; and an optical member provided with t...  
WO/2012/115706A3
Furfural is produced from a lignocellulosic feedstock comprising glucan and xylan. The feedstock is contacted with water in the presence of an acid catalyst. The resulting mixture is contacted with at least one water-immiscible organic s...  
WO/2012/113608A1
The invention relates to the use of pentyl esters of furandicarboxylic acid in softeners.  
WO/2012/113607A1
The invention relates to the use of C11-C13 dialkyl esters of furandicarboxylic acid in softeners.  
WO/2012/113829A1
The present invention relates to a heat-curable composition comprising (a) at least one compound which is capable of undergoing cationic polymerization; and (b) at least one sulfonium sulfate selected from compounds of the formulae Ia an...  
WO/2012/111449A1
The present invention is a method for efficiently producing an aromatic compound by an intramolecular cyclization reaction, the aromatic compound having a ring structure that includes a nitrogen atom or oxygen atom. An aromatic compound ...  
WO/2012/110833A2
The present invention relates to fluorescence lifetime modulators, conjugates comprising fluorescence lifetime modulators moieties and methods of making them. The present invention further relates to the use of the fluorescence lifetime ...  
WO/2012/112567A1
Small molecule inhibitors of AGBL2 are provided, as well as methods of using the inhibitors to treat or prevent cancer and neurologic disorders.  
WO/2012/110833A3
The present invention relates to fluorescence lifetime modulators, conjugates comprising fluorescence lifetime modulators moieties and methods of making them. The present invention further relates to the use of the fluorescence lifetime ...  
WO/2012/111849A1
Provided is a production method of an optically active dihydrobenzofuran derivative. A production method of an optically active form of a compound represented by the formula: wherein each symbol is as defined in the specification, or a s...  
WO/2012/111988A1
The present invention relates to an acid catalyst composition for preparing 5-chloromethyl-2-furfural from galactan derived from seaweed, and a method for preparing 5-chloromethyl-2-furfural from galactan derived from seaweed in a two-co...  
WO/2012/108472A1
Disclosed are: a novel substance which functions as a solid Lewis acid catalyst in the presence of water; a process for producing the same; use thereof as a solid Lewis acid catalyst; and a method for conducting a chemical reaction in an...  
WO/2012/108397A1
The purpose of the present invention is to provide a novel cationic lipid which forms lipid particles. Provided are: a compound represented by formula (I); lipid particles which contain the compound; nucleic acid lipid particles which co...  
WO/2012/103156A1
This application relates to derivatives of hydrocarbon terpenes (e.g., myrcene or farnesene), to methods of making the derivatives, and to the use of the derivatives as surfactants.  
WO/2012/102347A1
The present invention addresses the problem of providing a method for minimizing corrosion of a reactor device and reducing waste in the production of 2-furaldehyde from raw sugar that includes hexose as a constituent component, and addr...  
WO/2012/100375A1
Provided is a process for producing biomass-based product from straw hemicellulose and utilizing the components thereof thoroughly. Steam-explosion and acid-hydrolysis are combined in the pre-treatment of straw in the process, thus a hig...  
WO/2012/101015A1
The present invention relates to an improved process for manufacturing of esters of 2,5-furandicarboxylic acid (FDCA-esters) by reacting 2,5-furandicarboxylic acid (FDCA) with one or more alcohols in the presence of a heterogeneous catal...  
WO/2012/100809A1
The present invention relates to liquid-crystalline compounds having an O-heterocyclic ring, three partly fluorinated benzene rings and a -CF2O- bridge between the rings. The invention also relates to liquid-crystalline media produced th...  

Matches 551 - 600 out of 28,400