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Matches 651 - 700 out of 14,031

Document Document Title
WO/2012/017166
or an addition salt thereof with pharmaceutically acceptable acids, for use thereof in a method for treatment of a pathological condition linked to an excessive effect of TNF-alpha and for use thereof in a method for treatment of the hum...  
WO/2012/017052
Process for the synthesis of 2,5-furandicarboxylic acid through the oxidation of -hydroxymethylfurfural in a flow of oxygenor a compound containing oxygen, catalysed by a supported catalyst containing a metal of the platinum group, carri...  
WO/2012/017166
or an addition salt thereof with pharmaceutically acceptable acids, for use thereof in a method for treatment of a pathological condition linked to an excessive effect of TNF-alpha and for use thereof in a method for treatment of the hum...  
WO/2012/015265
Provided are novel organic electroluminescent compounds and an organic electroluminescent device using the same. Because the organic electroluminescent device using the organic electroluminescent compound as a hole transport material or ...  
WO/2012/014818
Disclosed are the following ether compound, and the use of the same. In formula (1), n represents 0 or 1, m represents an integer of 0-2, Y represents -O-, -S-, -C (=O) -O- and -O- C (=O) -, X1 and X2 represent a hydrogen atom or a fluor...  
WO/2012/014181
The invention relates to compounds of formula (I) for use in the prevention and/or treatment of viral infections: Wherein X, Y, Z, T, R1a and R1b are as defined in claim 1.  
WO/2012/015616
Methods for the production of dehydrated sugars and derivatives of dehydrated sugars using microwave (MW) irradiation and methods of purifying the same are described. The dehydrated sugars derivatives include 5-hydroxymethyl-2-furfural (...  
WO/2012/013016
The invention relates to the field of medicine. Curcumalactone derivatives with antitumor activity and the process for their preparation are disclosed. The said curcumalactone derivatives and their oxidized derivatives have a spironolact...  
WO/2012/014779
Disclosed is an organic electroluminescent element having the following attributes in high degree: high luminous efficiency, durability, low drive voltage, and inhibition of decreased luminous efficiency after high-temperature storage. A...  
WO/2012/010174
The present invention is concerned with a process in connection with the purification of a pharmaceutically acceptable salt of escitalopram or citalopram.  
WO/2012/012278
Disclosed are compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically related to GPR35, and/or GPR35-hERG signaling complex. For example, disclosed are compounds for preventing and/or treat...  
WO/2012/012278
Disclosed are compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically related to GPR35, and/or GPR35-hERG signaling complex. For example, disclosed are compounds for preventing and/or treat...  
WO/2012/010802
The invention relates to a process for preparing benzofuran derivatives of general formula I, in which R represents a nitro or ester-COOR' group, where R' represents an alkyl group, R1 represents hydrogen or an alkyl group and R2 represe...  
WO/2012/010555
The present invention discloses novel compounds useful for the inhibition of IL-6/STAT signaling and/or PI3K/ NF-ĸΒ signaling in the treatment of associated diseases or conditions, e.g. cancer. A pharmaceutical composition comprising s...  
WO/2012/010788
The invention relates to a process for preparing 5-aminobenzoylbenzofuran derivatives of formula (I), in which R1 represents hydrogen or an alkyl group and R2 represents hydrogen, an alkyl, alkoxy or dialkylaminoalkoxy group, by reductio...  
WO/2012/011128
A process for preparing the prostaglandin derivatives is provided, wherein the benzoyl and p-nitrobenzoyl groups are used as the hydroxyl protective groups. A pharmaceutical composition comprising the prostaglandin derivatives is also pr...  
WO/2012/011125
The present invention relates to compounds that have the ability to modulate the activity of GPR40 and are therefore useful in the treatment of GPR40 related disorders. In addition the invention relates to the compounds, methods for thei...  
WO/2012/010579
The present invention relates to fungicidal benzocycloalkene carboxamides or their thiocarboxamide derivatives of formula (I), their process of preparation and intermediate compounds for their preparation, their use as fungicides, partic...  
WO/2012/010913
The subject of the invention is a novel process for the preparation of N-[2-n-butyl-3-{4-[(3-di-n-butylamino)- propoxy]benzoyl}benzofuran-5-yl]-methanesulfonamide of formula (I), and pharmaceutically acceptable salts thereof characterize...  
WO/2012/009609
The invention provides for new flame retardant non-furan dicarboxylic acid (FDCA) based polyols; oligomers and polymers made from these new polyols with flame retardation properties; and methods of using them as a part or all of the flam...  
WO/2012/006686
The present invention relates to the scaled-up synthesis of biologically active compounds which display useful therapeutic activity in treating proliferative disorders. In particular the invention relates to process methods for the kilog...  
WO/2012/007959
Disclosed is a process for preparing dronedarone and pharmaceutically acceptable salts thereof. Also disclosed are a novel amorphous form of dronedarone hydrochloride and a preparation process thereof.  
WO/2012/008435
Disclosed is a novel biaryl amide derivative represented by formula (1) and having an affinity for the aldosterone receptor; also disclosed is a pharmaceutically acceptable salt thereof. (In the formula, A is any of the groups represente...  
WO/2012/004658
The present invention relates to a process for the preparation of highly pure N-[2- butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5- benzofuranyljmethanesulfonamide and pharmaceutically acceptable salts thereof having HPLC purity greater ...  
WO/2012/005200
An industrially advantageous method for producing an optically active 1,2-bis(dialkylphosphino)benzene derivative, wherein borane is removed from a phosphine-borane compound (1), followed by lithiation, then the reaction product is react...  
WO/2012/004658
The present invention relates to a process for the preparation of highly pure N- [2- butyl -3- [4- [3- (dibutylamino) propoxy] benzoyl] -5- benzofuranyljmethanesulfonamide and pharmaceutically acceptable salts thereof having HPLC purity ...  
WO/2012/004069
The invention relates to a process for producing compounds of the general formula (I) from compounds of the general formula (IIa) and/or (IIb) with an oxygen-containing gas in the presence of a catalyst composition, the reaction taking p...  
WO/2012/004658
The present invention relates to a process for the preparation of highly pure N-[2- butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5- benzofuranyljmethanesulfonamide and pharmaceutically acceptable salts thereof having HPLC purity greater ...  
WO/2012/002203
Disclosed is a production method for obtaining an optically active β-aminocarbonyl compound by a Mannich reaction of an aldimine in which nitrogen is protected and a malonic acid diester, in the presence of optically active BINOL and 1-...  
WO/2012/003164
The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity agamst hepatitis C virus (HCV) and may be useful in treating those infected wi...  
WO/2012/002512
A polymerisable compound having a terminal having an α-methylene-γ-butyrolactone group and a terminal having a photopolymer or a photocrosslinking group; a polymer for forming a liquid crystal aligning agent capable of aligning liquid ...  
WO/2012/002513
Disclosed is a polymerizable compound represented by formula (1). In formula (1), V represents a single bond or -R1O-, wherein R1 represents a linear or branched alkylene group having 1 to 10 carbon atoms, and W represents a single bond ...  
WO/2012/002511
The liquid crystal-aligning agent comprises polyimide precursor with side chains that vertically orient liquid crystals and photoreactive side chains that contain at least one kind selected from methacrylic, acrylic, vinyl and cinnamoyl ...  
WO/2012/002527
Provided are a novel heterocyclic compound and salt thereof applicable in the selective inhibition of the degradation of p27Kip1. The compound and the salt thereof are represented in formula (1). [In the formula: A represents an alkyl gr...  
WO/2012/001148
The present invention relates to calcium salts of compounds of the general formula (I) wherein X is selected from the group consisting of CH2, S, or O; D is O or S; R8 is hydrogen or alkyl; E is an optionally substituted phenylene group;...  
WO/2012/001151
The present invention relates to a salt selected from the group comprising the N-methyl-D- glucamine salt (NMG), the diethylamine salt (DEA) salt, the magnesium salt, the tromethamine salt, the choline salt, the L-arginine salt, the zinc...  
WO/2012/000608
The present invention relates to novel beta-aminoaldehyde derivatives of the formulae (I), (II) and (III), in which the substituents R1 to R5 and A have the meaning given in the description, to a novel process for their preparation, to i...  
WO/2012/001620
The present invention relates to a multilayer catalyst for preparing phthalic anhydride which has a plurality of catalyst layers arranged in succession in the reaction tube, with the individual catalyst layers having alkali metal content...  
WO/2012/000608
The present invention relates to novel beta-aminoaldehyde derivatives of the formulae (I), (II) and (III), in which the substituents R1 to R5 and A have the meaning given in the description, to a novel process for their preparation, to i...  
WO/2011/161945
Disclosed are a new alkoxyimino derivative or an agriculturally acceptable salt thereof and a pest control agent containing as an active ingredient the derivative or a salt thereof, wherein the agent shows an excellent controlling effect...  
WO/2011/161141
A process for separating furfural from a liquid aqueous phase comprising furfural and one or more organic acids, which process comprises a step a) extracting furfural from the liquid aqueous phase into a liquid aromatic phase comprising ...  
WO/2011/161201
A compound of formula (I). The compound is useful for treating cancer and inflammatory diseases. A pharmaceutical composition containing the compound.  
WO/2011/163610
The invention provides a compound of formula I:or a salt thereof, wherein R3-R8 and X and Y have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful as an...  
WO/2011/163610
The invention provides a compound of formula I:or a salt thereof, wherein R3-R8 and X and Y have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful as an...  
WO/2011/158050
This invention relates to a process for the preparation of N-[2-n-butyl-3-{4-[(3- dibutylamino)-propoxy]-benzoyl} - 1-benzofuran-5-yl]-methane-sulfonamide of formula (I) and its pharmaceutically acceptable salts, according to one of the ...  
WO/2011/159297
GPR120 agonists are provided. These compounds are useful for the treatment of metabolic diseases, including Type II diabetes and diseases associated with poor glycemic control.  
WO/2011/158928
Provided is a process for efficiently producing a trimellitic anhydride phenyl ester in high yield. The process for producing a trimellitic anhydride phenyl ester comprises subjecting a carboxylic acid phenyl ester and trimellitic anhydr...  
WO/2011/159781
The present invention includes antagonists of human type 2 taste receptors (hT2Rs) having structural Formula (I). The present invention also provides compositions containing these antagonists, the use of these antagonists for modulating ...  
WO/2011/157790
The present invention provides an organic electronic device including a first electrode, a second electrode, and an organic layer interposed between the first electrode and the second electrode, wherein the organic layer comprises an org...  
WO/2011/159781
The present invention includes antagonists of human type 2 taste receptors (hT2Rs) having structural Formula (I). The present invention also provides compositions containing these antagonists, the use of these antagonists for modulating ...  

Matches 651 - 700 out of 14,031