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Matches 51 - 100 out of 28,395

Document Document Title
WO/2014/154676A1
Disclosed is a method for the isomerisation of glucose by reduction to sorbitol and subsequent oxidation into fructose, in which the redox cofactors NAD+/NADH and NADP+/NADPH are regenerated in a one-pot reaction, wherein one of the two ...  
WO/2014/147271A1
The invention relates to a method for the synthesis of enantiomerically pure cyclic lactones, such as (S)-y-hydroxymethyl-α,β-butenolide and (S)-4-hydroxymethyl-y-butyrolactone and the derivatives thereof, characterised in that it comp...  
WO/2014/146604A1
Provided is a fused ring compound having GPR40 receptor function regulating action, and preparation method and pharmaceutical compositions thereof, and the use thereof in drugs for the treatment and/or prevention of diseases associated w...  
WO/2014/148053A1
This invention relates to a compound with EP4 antagonistic activity, or a pharmaceutically acceptable salt with EP4 receptor antagonistic activities, which is useful in the treatment of cartilage disease. This invention also relates to a...  
WO/2014/150384A1
A method for the manufacture of 1,8-octanedioic acid comprises: reacting gamma-valerolactone with an alcohol in the presence of an acid or a base catalyst to provide an alkyl pentenoate, converting the alkyl pentenoate in the presence of...  
WO/2014/148591A1
The present invention provides a method for efficiently producing an optically active 1, 2-diol compound from an olefin. The production method for the optically active 1, 2-diol compound is characterized by including: a step in which an ...  
WO/2014/139080A1
This invention relates to a novel method for the preparation of 3-oxotetrahydrofuran comprising oxidating 3-hydroxy-tetrahydrofuran in the presence of a catalytic amount of TEMPO with trichloroisocyanuric acid.  
WO/2014/140398A1
The invention concerns a method of obtaining organic molecules which involves at least the following steps: (a) a first step of selective oxidative esterification of the HMF formyl group with methanol in the presence of at least a metal ...  
WO/2014/142289A1
This method for manufacturing a lignin degradation product has: (1) a degradation step for degrading, under the conditions listed below, a raw material containing a plant-type biomass in a solvent that is a mixed solvent of water and a f...  
WO/2014/140017A1
This invention relates to a novel method for the preparationof 3-oxotetrahydrofurancomprising oxidating 3-hydroxy-tetrahydrofuran in the presence of a catalytic amount of TEMPO with trichloroisocyanuric acid.  
WO/2014/142219A1
[Problem] To provide a compound useful as a drug for preventing and/or treating kidney disease. [Solution] The inventors studied compounds having trypsin-inhibiting activity, confirmed that guanidinobenzoic acid ester compounds have tryp...  
WO/2014/141725A1
An anthracene derivative represented by formula (1). In formula (1), L1 is selected from a single bond and a linking group, the linking group being selected from groups formed by linking 2 to 4 of the following: bivalent arylene groups, ...  
WO/2014/139963A1
The invention is directed to a cosmetic composition and the precursor thereof. The composition has solid agent and liquid agent, both of which are cosmetic benefit ingredients. The solubility of solid agents in liquid agents in the inven...  
WO/2014/138823A1
The present disclosure relates to compounds of formula I in the treatment and/or prevention of a Gram-negative bacterial infection in a multicellular organism. The disclosure also relates to a pharmaceutical composition comprising said c...  
WO/2014/137301A1
It has been aimed in this invention to synthesize novel compounds having an original diflunisal hydrazide-hydrazone and 4-thiazolidone structures which may have the effect to inhibit DNA gyrase enzymes and which may be anticancer and HCV...  
WO/2014/135776A1
The invention relates to abexinostate tosylate of formula (II): and the crystalline form I thereof, characterized by the powder diffraction pattern X thereof, the Raman spectrum thereof, and the solid state 13C CP/MAS NMR spectrum thereo...  
WO/2014/135095A1
Provided are compounds of formula (I) and methods of controlling insects, acarines, nematodes or molluscs, which comprises applying to a pest, to a locus of a pest, or to a plant susceptible to attack by a pest an insecticidally, acarici...  
WO/2014/132178A2
The present invention concerns the use of a furfural derivative of formula (I) in which R represents (i) a -CH=CR'1-COR1 group, a group (ii), a group (iii), a group (iv) or a -CHO group and R' represents a hydrogen atom or a (C1-C4)alkyl...  
WO/2014/133416A3
The present invention relates to novel chemical compounds of general formula 1 which are intermediate products of the synthesis of androgen receptor inhibitors that are of interest as anticancer preparations. The subject matter of the in...  
WO/2014/133361A1
The present invention relates to: a compound selected from the group consisting of a tricyclic compound having the structure of formula I, a pharmaceutically acceptable salt, an isomer, a solvate and a precursor thereof; and a use thereo...  
WO/2014/132975A1
In this method, a diastereomeric mixture containing a (2R)-2-fluoro-2-C-methyl-D-ribono-γ-lactone precursor is deprotected under acidic conditions; subsequently, by lactonizing the same, a diastereomeric mixture of dihydroxylactone is o...  
WO/2014/131825A1
The present invention relates to a multilayer tablet formulation comprising a combination of quetiapine or a pharmaceutically acceptable salt thereof and escitalopram or a pharmaceutically acceptable salt thereof.  
WO/2014/132178A3
The present invention concerns the use of a furfural derivative of formula (I) in which R represents (i) a -CH=CR'1-COR1 group, a group (ii), a group (iii), a group (iv) or a -CHO group and R' represents a hydrogen atom or a (C1-C4)alkyl...  
WO/2014/129846A1
The present invention relates to organic electroluminescent compounds of formula 1 (see below) wherein X, A, B, C and R4, R5, R6, R7, a, b, c. d. e, l, m, and n are as defined in the description. The invention also relates to organic ele...  
WO/2014/129874A1
The present invention relates to: a novel α,β-unsaturated amide compound; a method for preparing a composition for preventing or treating obesity, comprising the steps of selecting a compound showing an obesity prevention or treatment ...  
WO/2014/129612A1
The present invention provides a process for producing a compound of the formula (1) wherein X represents a hydrogen atom, etc., and Y represents a hydrogen atom, etc., which comprises step 1 of reacting a compound of the formula (2) and...  
WO/2014/128723A2
The invention disclosed herein relates to novel Peribysin E analogues of general formula-I. Further the invention provides simple, economical and short synthesis of Peribysin E and its analogues of Formula I, in good yield and purity lea...  
WO/2014/125145A1
The invention relates to a novel method for modifying hydroxylated cyclic amino acids, especially 4-hydroxyproline, which is a commercial, relatively cheap, natural amino acid, in order to provide other amino acids of high optical purity...  
WO/2014/124552A1
The present invention relates to N-substituted amino butyrolactone derivatives and uses thereof. In particular, the present invention relates to compounds of formula I or pharmaceutically acceptable salts, solvates, esters, prodrugs, iso...  
WO/2014/125075A1
The present invention relates to a antibiotically active compounds characterized by general formula (I), wherein X1, BB, BC, BD, BE and X2 are building blocks with D1, D2, D3, D4 or D5 being linkers which comprise carbon, sulphur, nitrog...  
WO/2014/126068A1
The present invention provides a catalyst precursor which contains ruthenium that has a first ligand, which is a chiral cyclic diene ligand, and a second ligand.  
WO/2014/122067A1
The present invention relates to compounds of general formula I, (I) wherein the group R1 is defined as in claim 1, which have valuable pharmacological properties, in particular bind to the G-protein coupled receptor 40 (GPR40, also know...  
WO/2014/123203A1
Provided is a compound having PTP-1B inhibitory activity that is excellent as a drug, or a pharmaceutically acceptable salt thereof. A compound represented by general formula (I) (in the formula, each symbol means the same as in the spec...  
WO/2014/121513A1
The present invention concerns a process for the production of an aldehyde compound by an oxidation reaction of an alcohol compound in the presence of a mesostructured vanadium phosphorus mixed oxide catalyst, at a temperature comprised ...  
WO/2014/122142A1
The present invention concerns a process for the production of an aldehyde compound by an oxidation reaction of an alcohol compound in the presence of a mesostructured vanadium phosphorus mixed oxide catalyst, at a temperature comprised ...  
WO/2014/124358A1
The resin composition comprises pellets having a diameter of less than about 1 mm, for example, 0.75 ± 0.24 mm, and a length/ diameter (UD) ratio of from 0.5 to 2.0. It is further provided a method for manufacturing such a micropelletiz...  
WO/2014/122319A1
The present invention concerns a method for preparing 2,5-furandicarboxylic acid (FDCA) by oxidising 5-hydroxymethylfurfural (HMF) in water in the presence of a weak base and a supported catalyst comprising platinum and bismuth, in which...  
WO/2014/123369A1
The present specification relates to an organic electronic element having an organic material layer containing a novel compound which is capable of improving the lifespan, efficiency, electrochemical stability, and thermal stability of t...  
WO/2014/121633A1
Disclosed are a derivative of homoserine lactone shown in formula I, and a preparation method and use thereof. The compound has a function of sensing and regulating a bacterial colony, and can be used for prevention and/or treatment of r...  
WO/2014/118556A3
Sphingosine 1-phosphate (S1P) is involved in hyper-proliferative diseases, such as cancer and vascular remodeling in pulmonary arterial hypertension. Inhibitors of sphingosine kinase 1 and 2 (SK1 and SK2), which catalyze the synthesis of...  
WO/2014/120790A1
Methods and compositions of this invention relate to suppressing Ca2+-Release-Activated- Ca2+ (CRAC) channel activity using novel compounds of Formula (I): Compounds of formula (I) have been shown to modulate calcium transport through th...  
WO/2014/118046A1
The invention relates to a method for the carbonylation of olefins, in which at least one olefin is converted with the addition of H2 and CO in the presence of a catalytic system consisting of a ruthenium complex and at least one ligand,...  
WO/2014/118806A9
The present patent discloses a one step process for the synthesis of THF and related ring hydrogenated products form furfural using Palladium metal based carbon supported catalyst with high selectivity and 100% conversion in both batch a...  
WO/2014/119892A1
The present disclosure relates to a novel method for preparing an arylnaphthalene lignan compound. In synthesis of arylnaphthalene lignan compounds and derivatives according to the present disclosure, a naphthalene backbone may be constr...  
WO/2014/118120A1
The present invention relates to new compositions, cross-linkable rubber mixtures containing these compositions, processes for their production and their use in automotive applications, as retarder, especially to reduce Mooney viscosity,...  
WO/2014/118806A1
The present patent discloses a one step process for the synthesis of THF and related ring hydrogenated products form furfural using Palladium metal based carbon supported catalyst with high selectivity and 100% conversion in both batch a...  
WO/2014/113700A1
The present disclosure provides nitroxyl donating pharmaceutical compositions comprising N-substituted hydroxylamine derivatives. The compositions are highly efficacious in treating cardiovascular diseases (e.g., heart failure), have a s...  
WO/2014/113407A3
Inhibitors of EYA tyrosine phosphatase having the structure of Formula I are provided herein. The compounds are useful fo the treatment of certain proliferative diseases and cancer.  
WO/2014/112646A1
The present invention addresses the problem of providing a compound having a selective inhibitory activity on LAT-1 that can be expressed in a tumor cell at a high level. The present invention provides: a compound represented by formula ...  
WO/2014/111446A1
The invention relates to a process for the production of 5-formylvaleric acid and adipic acid or esters thereof from an isomeric mixture of pentenoic acid or esters thereof said mixture comprising at least 4-pentenoic acid or esters ther...  

Matches 51 - 100 out of 28,395