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Matches 101 - 150 out of 32,296

Document Document Title
WO/2018/150421A1
The invention provides efficient cyclization processes of hydroxyalkenoic acids and products produced therefrom. The following reactions are claimed: Formula (I), (II), (V) and (VI).  
WO/2018/149940A1
It is described an industrially viable and advantageous process for the preparation of (N- (((1R,2R)-2-(2,3-dihydrobenzofuran-4-yl)cyclopropyl)methyl)p ropionamide, compound having the formula depicted below and generally known as Tasime...  
WO/2018/149853A1
The present invention relates to novel compounds, particularly to compounds comprising a photoactive unit, said novel compounds being particularly suitable for compositions and ophthalmic devices as well as to compositions and ophthalmic...  
WO/2018/149991A1
The present invention relates to particular sulfonamide derivatives, the pharmaceutically acceptable addition salts thereof, the hydrates thereof and/or the solvates thereof, and also the use thereof as inverse agonists of retinoid-relat...  
WO/2018/149852A1
The present invention relates to novel compounds (I) particularly to compounds comprising a photoactive unit, said novel compounds being particularly suitable for compositions and ophthalmic devices as well as to compositions and ophthal...  
WO/2018/147094A1
A compound represented by formula (I). (In formula (I), each of R1 and R2 independently represents a hydrogen atom or a methyl group; each of X1 and X2 independently represents a group that is represented by one of formula (X1-1) to form...  
WO/2018/146894A1
The problem addressed by this invention is to provide an organic electric field light-emitting element having optimal light-emitting characteristics. This problem is addressed by an organic electric field light-emitting element containin...  
WO/2018/146978A1
Provided is catalyst (for reduction reaction) which uses a raw material derived from biomass such that 1,4-butanediol or tetrahydrofuran can be obtained with a higher selectivity than is typical. This catalyst is used for a reduction rea...  
WO/2018/146122A1
The presently claimed invention is directed to a process for preparing D-glucaro-6,3-lactone from a salt of D-glucaric acid.  
WO/2018/145553A1
The present disclosure provides co-crystals of a substituted glycine compound and a co-former compound of Formula (I), compositions comprising such, and uses thereof in treating and/or reducing the risk for a neuropsychiatricdisorder (e....  
WO/2018/146962A1
The purpose of this invention is to provide an organic electric field light-emitting element having optimal light-emitting characteristics. This problem is solved by an organic electric field light-emitting element having a light-emittin...  
WO/2018/147373A1
A tetracarboxylic acid dianhydride which is composed of at least one acid dianhydride (A) selected from the group consisting of compounds having an endo/exo type steric structure represented by a specific general formula and enantiomers ...  
WO/2018/141706A1
The invention relates to propellane compounds according to defined formula, to the use of said compounds in electronic devices, and to electronic devices containing one or more of the known propellane compounds. The invention also relate...  
WO/2018/141854A1
The present invention provides piperazine derivatives exhibiting high affinity to the stem region (viral membrane proximal part) of influenza hemagglutinin as determined through competition binding and high virus neutralization activity ...  
WO/2018/144910A1
The disclosure provides a method of preventing or reducing protein aggregates using combretastatin-A4 (CA4) or an analog thereof. The disclosure also provides methods of reducing the risk, delaying the onset, delaying or slowing the prog...  
WO/2018/138359A1
The present invention provides novel compounds of formula (la) that are modulators of RORgamma. These compounds, and pharmaceutical compositions comprising the same, are suitable means for treating any disease wherein the modulation of R...  
WO/2018/137959A1
The present invention relates to a process for preparing benzylic amides of formula (I) wherein the variables have the meaning as defined in the description, by reductive amidation of a nitrile of formula (II) wherein the variables have ...  
WO/2018/140599A1
Compounds having activity as inhibitors of G12C mutant KRAS protein are provided. The compounds have the following structure (I) or a pharmaceutically acceptable salt, stereoisomer or prodrug thereof, wherein B, Z, Ra, Rb, Rc, R1, L, L1 ...  
WO/2018/139767A1
The present invention provides a novel amine-based compound and an organic light emitting device using the same.  
WO/2018/139787A1
The present invention relates to a method for purifying phenol, the method comprising the steps of: contacting a phenol stream, which contains hydroxy acetone, 2-methylbenzofuran, 3-methylbenzofuran, and phenol, with an acyl chloride, in...  
WO/2018/133790A1
The present disclosure relates to heteroaromatic containing organic compounds and methods of use and preparation thereof. The compounds disclosed herein can be used as organic semiconductors.  
WO/2018/133716A1
The present invention provides a heterocyclic urea compound as an indoleamine-2,3-dioxygenase inhibitor, a preparation method thereof, and a use of the heterocyclic urea compound as an indoleamine-2,3-dioxygenase inhibitor or a pharmaceu...  
WO/2018/135798A1
The present invention provides a novel heterocyclic compound and an organic light emitting element using the same.  
WO/2018/136792A1
The present disclosure provides compounds and methods for inhibiting or degrading the N-terminal domain of the androgen receptor, as well as methods for treating cancers such as prostate cancer.  
WO/2018/130625A1
The present invention relates to novel substituted benzene disulfonamides, as well as pharmaceutical compositions containing at least one of these substituted benzene disulfonamides together with at least one pharmaceutically acceptable ...  
WO/2018/132660A1
Disclosed herein are inhibitors of the Integrator complex, and methods for their use in treating or preventing diseases, such as cancer. The inhibitors described herein can include compounds of Formula (I) and pharmaceutically acceptable...  
WO/2018/130865A1
A composition for treating headaches and migraines and methods of using same for preventative use to decrease the frequency, duration and severity of headaches and migraines in children and adults.  
WO/2018/130155A1
Compounds serving as histone deacetylase 6 (HDAC6) selective inhibitors, and applications thereof in the preparation of drugs for treating HDAC6-related diseases. Specifically disclosed are a compound as represented by formula (I) and a ...  
WO/2018/122454A1
Ina method and an apparatus furfuralis recovered from a steam stream (3) which is formed in a treatment of a pretreated wood based material (1).The pretreated wood based material (1) which comprises at least carbohydrates is treated in a...  
WO/2018/121329A1
Disclosed are a magnetic metal oxide crosslinked acidic poly(ionic liquid) and the use thereof, wherein same belong to the technical field of solid acid catalysis. The catalyst prepared by the present invention has a good Lewis acidic si...  
WO/2018/124088A1
Provided are novel pest control agents, in particular, a bactericide and a nematicide. An alkylphenyl-substituted amide compound represented by formula (I) [wherein: G1 stands for a structure represented by G1-2, G1-3, G1-4, etc.; X1 sta...  
WO/2018/122453A1
In a method and an apparatus furfural is separated from a material stream (3) which is formed in a treatment of a pretreated wood based material (1). The material stream (3) which comprises at least furfural is introduced to a separation...  
WO/2018/115421A1
The present invention discloses compounds of formula (I) that are useful in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).  
WO/2018/114534A1
The present invention relates to a method for production of a fuel composition, more specifically a middle distillate fuel composition, and a composition - in particular a co feed composition comprising a furanyl containing oligomerisati...  
WO/2018/113599A1
The present invention concerns a process for preparing a tetrahydrofuran compound comprising at least two amine functional groups by reacting a furan compound comprising at least two nitrogen-containing functional groups with hydrogen in...  
WO/2018/116081A1
Certain embodiments are directed to an integrated process for the production of Maleic Anhydride (MAN), 1,4 Butanediol (BDO), Gamma-ButyroLactone (GBL), and PolyButylene Terephthalate (PBT) utilizing NC4 rich stream from a recycle stream...  
WO/2018/113785A1
Provided are a polymer containing a furan crosslinking group and the use thereof in an organic electronic device. Provided is a polymer containing a furan crosslinking group, having the following general formula (I): wherein x and y resp...  
WO/2018/118782A3
Novel benzofurans, benzothiophenes and indoles useful as inhibitors of tau oligomer formation, useful for the treatment of neurodegenerative diseases and related conditions are disclosed. The invention also relates to the pharmaceuticall...  
WO/2018/117152A1
The purpose of the present invention is to provide: a method for producing a 7H-pyrrolo[2,3-d]pyrimidine derivative which is useful as a Janus kinase (JAK) inhibitory agent; an intermediate of the same; and a method for producing the int...  
WO/2018/117493A1
The present invention relates to a novel compound and an organic electroluminescent device comprising the same. According to the present invention, the compound is used in an organic material layer, preferably in a light-emitting layer, ...  
WO/2018/109781A1
The present invention provides an improved process for preparation of Firocoxib of Formula I. Further, the present invention relates to novel process for the preparation of crystalline polymorphic form B of Firocoxib of Formula I.  
WO/2018/110887A1
The present invention provides a heterocyclic compound having a novel structure, and an organic light-emitting element comprising the heterocyclic compound.  
WO/2018/104856A1
A process of obtaining a purified geometric isomer of an unsaturated macrocyclic compound is disclosed herein. The process is effected by contacting an ion exchange medium comprising silver ions with a mixture comprising at least one geo...  
WO/2018/104305A1
Substituted aromatic sulfonamides of formula (I) which are antagonists or negative allosteric modulators of P2X4, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing a ph...  
WO/2018/104295A1
Disclosed are sulfonamide analogues of galiellactone of formula (I) as STAT3-inhibitors for use in the treatment of a STAT3 signaling related disorder, e.g. solid cancers, hematological cancers, benign tumors, hyperproliferative diseases...  
WO/2018/102427A1
Provided herein are methods of preparation of I by reacting i with acid where R1 and R2 are each independently a leaving group. Intermediates to make i are also claimed.  
WO/2018/099432A1
The present invention relates to a fused ring compound and a preparation method and application thereof. The fused ring compound is represented by general formula (I). The fused ring compound emits fluorescence at a short wavelength, and...  
WO/2018/100184A1
The invention relates to a method for producing 5-hydroxymethylfurfural (HMF) in a continuous process, which leads to the obtainment of an HMF fraction, a carbohydrate/acid fraction, a fructose fraction, and a levulinic-acid and formic-a...  
WO/2018/100016A1
The present invention relates to 1-fluorocyclohexyl-methoxy-aryl compounds of formula (I), in which R1, R2, A1, A2, m and n are defined as indicated in claim 1, to their production, to their use as components in liquid crystal media and ...  
WO/2018/101329A1
The purpose of the present invention is to develop a therapeutic agent for inflammatory diseases such as inflammatory bowel disease and NASH, said therapeutic agent having few adverse effects and high efficacy. The present invention prov...  

Matches 101 - 150 out of 32,296