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WO/2012/147897 |
With the method for producing an amine compound (5) according to the present invention, that includes the following steps, it is possible to produce an amine compound regardless of the presence of inorganic salts. Step (1), a step in whi...
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WO/2012/146374 |
Novel compounds of formula (I) their use as germination trap for parasitic weeds, for the regulation of branching, tillering and root development, for enhancement of cambium growth, for the regulation of hyphal growth of mycorrhizal fung...
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WO/2012/148530 |
Polyol ether compounds and processes for their preparation. A representative process comprises melting a polyol, and reacting the molten polyol, a carbonyl compound, and hydrogen in the presence of a hydrogenation catalyst to provide the...
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WO/2012/146085 |
Disclosed is an intermediate (structural formula I) for synthesizing prostaglandin medicines and preparation method therefor. The intermediate is used for synthesizing prostaglandin medicines, such as bimatoprost, travoprost, latanoprost...
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WO/2012/144650 |
Provided by the present invention is a method for efficient oxidation of alcohols by using, as a catalyst for dehydrogenation oxidation, a ruthenium complex which can be easily produced and easily handled and is obtainable at a relativel...
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WO/2012/145678 |
The invention provides compounds of formula I, formula II, formula III, formula IV, and formula V: and salts thereof wherein X, Z, ---, and R1-R9 have any of the values defined in the specification, as well as compositions comprising the...
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WO/2012/144064 |
Provided are: a composition containing scirpusin B, which is a composition derived from a natural material and contains scirpusin B at a high content; and a process for producing the composition containing scirpusin B. A composition cont...
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WO/2012/142288 |
The present invention relates to novel phenyl bicyclic methyl amine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
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WO/2012/141229 |
The present invention provides a novel stable organic compound and also provides an organic light-emitting device having a high luminous efficiency and a low driving voltage. The present invention relates to a spiro compound represented ...
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WO/2012/139522 |
Disclosed are a dehydrocostus lactone derivative as represented by formula (I) or salts thereof, a compound having a therapeutic dose as represented by formula (I) or salts thereof, pharmaceutical compositions of pharmaceutically accepta...
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WO/2012/142377 |
The present invention relates to novel bicyclic methyl amine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1 -phosphate receptors.
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WO/2012/141038 |
The purpose is to select a low-molecular-weight compound which is effective for inducing the differentiation of a mesenchymal stem cell into a hepatocyte and develop a differentiation-inducing method which has excellent efficiency of ind...
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WO/2012/141197 |
An electroluminescence element that uses a compound represented by the illustrated general formula has low intermolecular interactions, and high orientation during vapor deposition, and by using compounds that have difficulty associating...
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WO/2012/135980 |
Provided is a continuous hydrolysis kettle, which comprises a cylinder (5) and an internal lining (11). The cylinder (5) is provided with a feed inlet (1) and an aldehyde steam outlet (4) on the top, and with a slag-discharging outlet (3...
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WO/2012/138297 |
The present invention relates to the use of a compound of Formula I for the manufacture of a medicament for treating or preventing cancer in a subject. Formula I
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WO/2012/131410 |
The invention relates to a novel process for preparation of drohedarone of formula (I) and pharmaceutically acceptable salts thereof characterized in that a compound of formula (II) is reacted in the presence of a reductive agent with bu...
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WO/2012/130299 |
Novel compounds of the formula (I) wherein R1, R2, D, A, B and X have the meanings defined herein, pharmaceutical compositions comprising them as active ingredient, as well as their use in medicine, in particular as peptidase inhibitors,...
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WO/2012/131028 |
The invention relates to a carbonylation process for the preparation of a compound of formula (I) XOOC-(CH2)4-COOY (I) wherein X and Y can independently represent H and/or alkyl, said carbonylation process comprising reacting: (a) a comp...
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WO/2012/134258 |
The use or methods of use of extracts comprising one or more special clerodane compounds against inflammatory (including allergic) diseases or conditions, as well as novel compounds of this type, said clerodane derivatives for use agains...
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WO/2012/133861 |
An amide compound represented by the formula (I): [wherein, R1, R2, R3, R4, R5, R6, R7, R8, X, W, r, n and Y are as defined in the description] has an excellent control effect on harmful arthropods.
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WO/2012/133653 |
This charge transport material, which comprises a compound represented by the formula, has a high efficiency and drive durability after high-temperature storage, and resists the occurrence of dark spots (X101 represents a sulfur atom or ...
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WO/2012/133644 |
An organic electroluminescent element, which comprises a substrate, a pair of electrodes including a positive electrode and a negative electrode that are arranged on the substrate, and an organic layer that is arranged between the electr...
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WO/2012/131063 |
An oligo-or polyimide comprising one or two residue(s)of an anhydride based acetylenic end-capper, at least one EBPA residue, at least oneresidueof anaromatic di- amine,and optionally at least one residue of an aromatic non-acetylenic di...
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WO/2012/131409 |
The invention relates to a novel process for preparation of dronedarone (I) and pharmaceutically acceptable salts thereof where the compound of formula (II) or salt thereof is reacted with a compound of formula L-(CH2)3-CH3 (III), where ...
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WO/2012/131408 |
The invention relates to a novel process for preparation of N-[2-n-butyl-3-[4-[3-(di-n- butylamino)-propoxy]-benzoyl]-benzofuran÷5-yl]methanesulfon
amide (I) and pharmaceutical acceptable salts thereof, where a salt of (5-amino-2-butyl-...
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WO/2012/131027 |
The invention relates to a carbonylation process for the preparation of an alkanoic acid ester comprising reacting: (a) an alkene; (b) a source of Pd; (c) a bidentate phosphine ligand of formula I; R1R2P - R3 - R - R4 - PR5R6 (I) wherein...
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WO/2012/129452 |
This invention discloses a series of novel propynoic acid carbamoyl methyl-amides (PACMAs), methods for synthesizing the PACMAs and pharmaceutical compositions containing the PACMAs. These novel compounds and compositions show cytotoxici...
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WO/2012/129452 |
This invention discloses a series of novel propynoic acid carbamoyl methyl-amides (PACMAs), methods for synthesizing the PACMAs and pharmaceutical compositions containing the PACMAs. These novel compounds and compositions show cytotoxici...
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WO/2012/129473 |
The present invention provides complexes of gallium with a ligand, methods of making the complexes, methods of using the complexes and pharmaceutical gallium compositions comprising the complexes, in particular those compositions suitabl...
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WO/2012/127173 |
The invention relates to a process for synthesizing benzofuran derivatives, in particular dronedarone of formula (D), comprising a step of Friedel-Crafts acylation starting from a sulfonamido-benzofuran ester intermediate.
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WO/2012/129452 |
This invention discloses a series of novel propynoic acid carbamoyl methyl-amides (PACMAs), methods for synthesizing the PACMAs and pharmaceutical compositions containing the PACMAs. These novel compounds and compositions show cytotoxici...
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WO/2012/127174 |
The invention relates to a method for synthesizing benzofuran derivatives, in particular the dronedarone of formula (D), including carrying out a Fries rearrangement reaction using a sulfonamido-benzofuran ester intermediate.
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WO/2012/128510 |
The present invention relates to a method for preparing a furfuranol-based compound and a 2-furancarboxylic acid-based compound by reacting a furfural-based compound with the hydroxide of an alkali metal or alkaline earth metal using an ...
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WO/2012/128510 |
The present invention relates to a method for preparing a furfuranol-based compound and a 2-furancarboxylic acid-based compound by reacting a furfural-based compound with the hydroxide of an alkali metal or alkaline earth metal using an ...
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WO/2012/123957 |
This invention relates to oligopeptides having general formula (I). The invention also relates to the process of preparation thereof, wherein the said compounds are selective anti-cancer agents over a panel of human cancer cell lines. Fu...
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WO/2012/124696 |
[Problem] To provide a compound which is useful as an active ingredient of a pharmaceutical composition, especially of a pharmaceutical composition for the prophylaxis and/or treatment of VAP-1 associated diseases. [Solution] As a result...
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WO/2012/121248 |
A method for highly enantio-selectively producing an optically active spirolactone compound using a iodoarene derivative which can be easily synthesized and scarcely racemized. From 2,6-dihydroxyiodoarene, a flexibly designable hypervale...
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WO/2012/119927 |
The invention relates to a method for producing primary amines comprising at least one functional group of formula (-CH2-NH2), by alcohol amination of educts which comprise at least one functional group of formula (–CH2-OH), using ammo...
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WO/2012/120544 |
The present invention provides a process for preparing compound of formula (I),
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WO/2012/120544 |
The present invention provides a process for preparing compound of formula (I),
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WO/2012/119265 |
The present invention discloses esters of 4,9-dihydroxy-naphtho[2,3-b]furans and methods of making and using the same. The present invention also discloses conversion of the esters into therapeutically active 4,9-dihydroxy-naphtho[2,3-b]...
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WO/2012/119928 |
The invention relates to a method for producing alkanol amines which comprise a primary amino group (-NH2) and a hydroxyl group (-OH), by alcohol amination of diols comprising two hydroxyl groups (-OH), using ammonia, and elimination of ...
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WO/2012/116977 |
The invention relates to a process for the preparation of 3-methylene-γ-butyrolactone (Z), the process comprising a hydroformylation step wherein 1,4-butene-diol (X) or its ester derivative cis-1,4-diacetoxy butene (Y) is subjected to H...
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WO/2012/117015 |
A process for preparing sodium salts or potassium salts of 4-hydroxy-2-oxo-2,5-dihydrofuran-3-carboxylate, comprising the reaction of a malonic ester with potassium hydroxide to give the corresponding malonic ester potassium salt of the ...
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WO/2012/118286 |
The present invention relates to a novel compound isolated from Kaempferia pandurata Roxb and the use thereof as an antiviral agent. The compound isolated from Kaempferia pandurata Roxb shows the ability to inhibit highly pathogenic viru...
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WO/2012/115578 |
The present invention concerns the synthesis of substantially anomerically pure 2,3-dideoxy-3- fluoro-5-0-(4-phenylbenzoyl)-a-D-erythropentofuranosyl chloride from an α/β-mixture of the corresponding methyl glycoside. The method of the...
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WO/2012/113609 |
The invention relates to the use of heptyl esters of furan dicarboxylic acid as softeners.
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WO/2012/115129 |
Provided are: the polymeric liquid crystal compound represented by formula [1]; a polymeric liquid crystal composition containing same; a polymer, coating film, and oriented film obtained using same; and an optical member provided with t...
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WO/2012/115706 |
Furfural is produced from a lignocellulosic feedstock comprising glucan and xylan. The feedstock is contacted with water in the presence of an acid catalyst. The resulting mixture is contacted with at least one water-immiscible organic s...
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WO/2012/113608 |
The invention relates to the use of pentyl esters of furandicarboxylic acid in softeners.
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