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Matches 301 - 350 out of 28,430

Document Document Title
WO/2013/166618A1
The present invention discloses use of prodrug of 4,9-dihydroxy-naphtho[2,3-b]furan derivative for circumventing cancer multidrug resistance. The present invention also discloses use of prodrug of 4,9-dihydroxy-naphtho[2,3-b]furan deriva...  
WO/2013/164292A1
The present invention relates to compounds of general formula (I), wherein the groups R1, R2 and m are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activ...  
WO/2013/164729A1
Provided herein is an improved, commercially viable and industrially advantageous process for the preparation of a prostaglandin derivatives and intermediates thereof, in high yield and purity.  
WO/2013/158251A1
The invention relates to fluorinated compounds and their use in the field of pathological syndromes of the cardiovascular system. Novel fluorinated benzofuran derivatives of amiodarone and pharmaceutically acceptable salts or solvates th...  
WO/2013/156398A1
The present invention relates to novel processes for improved preparation of homofarnesol, especially of (3E,7E)-homofarnesol and homofarnesol preparations having an elevated content of (3E,7E)-homofarnesol (also referred to as all-E-hom...  
WO/2013/157528A1
Provided is a medicinal agent comprising a compound represented by general formula (1), a pharmaceutically acceptable salt of the compound or a solvate of the compound or the pharmaceutically acceptable salt. A compound represented by ge...  
WO/2013/156738A2
Lichesterinic acid and the derivatives of same as pigmentation inhibitors. The invention relates to the cosmetic use of a compound chosen from the compounds of formula (A) and the salts of same as an agent for depigmenting the skin and/o...  
WO/2013/156200A1
A process for obtaining (ethyne-1,2-diyl)bis(isobenzofuran-1,3-dione) is disclosed. In the disclosed process chloro-, bromo-, or iodoisobenzofuran-1,3-dione is reacted with ethyne in a solvent in the presence of a dissolved homogenous pa...  
WO/2013/156738A3
Lichesterinic acid and the derivatives of same as pigmentation inhibitors. The invention relates to the cosmetic use of a compound chosen from the compounds of formula (A) and the salts of same as an agent for depigmenting the skin and/o...  
WO/2013/152963A1
The invention relates to a polycondensation product comprising, as monomer components, at least one aryl polyoxyalkylene ether, at least one vicinally disubstituted aromatic compound, at least one aldehyde, and optionally further aromati...  
WO/2013/144098A1
The present invention relates to compounds of general formula (I), wherein the groups R1, R2 and m are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activ...  
WO/2013/144931A3
The T cells specific to human collagen type II, one of the possible autoantigens, have a crucial role in the development of rheumatoid arthritis in the context of HLA-DR4. The protein-protein interactions between the T cell receptor (TCR...  
WO/2013/146943A1
An arctigenin derivative is created and used for anti-aging treatment, including in order to protect skin from the sun and to recover skin elasticity. A variety of fatty acid ester derivatives, alcohol ether derivatives and alkylated der...  
WO/2013/146437A1
[Problem] To provide a novel compound that is useful as an agent for preventing/treating cancer. [Solution] One aspect of the present invention provides a compound expressed by the chemical formula (1) or a pharmaceutically permissible s...  
WO/2013/148255A1
Compositions containing tetrahydrofurfuryl and/or alkyl-substituted tetrahydrofurfuryl esters of citric acid are provided. These esters of citric acid can be formed from renewable materials and can be used, for example, as plasticizers f...  
WO/2013/142999A1
Disclosed is a compound of formula (1), or a pharmaceutically acceptable salt thereof, where R1, R2, R3, R4, R5, R6, R7, R7', R8, R9, R10, R11, R12 and R13 are as disclosed herein. Also, disclosed is a process for the preparation of the ...  
WO/2013/148923A1
Provided are catalysts suitable for the production of tetrahydrofuran from 1,4- butanediol. Also provided are methods of use of these catalyst, as well as catalyst systems. The catalysts described herein contain only Lewis acidity, but n...  
WO/2013/146085A1
The present invention relates to: a method for producing 5-hydroxymethyl furfural (HMF), which comprises the steps a-c described below; and a method for producing 5-hydroxymethyl furfural oxide, which comprises the steps a-d described be...  
WO/2013/148620A1
The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected w...  
WO/2013/143259A1
The present invention relates to a phosphodiesterase-4 inhibitor capable of avoiding a vomit reaction. The phosphodiesterase-4 inhibitor is a compound, a prodrug or a solvate represented by DTPM. The name of DTPM is 1-(4-difluoro methoxy...  
WO/2013/147568A1
The present invention provides an aminostyrylbenzofuran compound of Formula (I), and a pharmaceutical composition comprising same. The pharmaceutical composition of the present invention comprising the compound of Formula (I), a pharmace...  
WO/2013/144097A1
The present invention relates to compounds of general formula I, (I), wherein the groups R1, R2 and m are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its ac...  
WO/2013/141523A1
The present invention relates to a method for preparing 5-acetoxymethylfurfural, comprising a step of synthesizing 5-acetoxymethylfurfural by reacting 5-halomethyl furfural with alkylammonium acetate. The present invention can provide a ...  
WO/2013/140969A1
The present invention is a photoresist composition which contains [A] a polymer that has a structural unit (I) containing an acid-cleavable group and a compound (I) that is represented by formula (1). In formula (1), each of R1, R2, R3 a...  
WO/2013/140946A1
Provided is a novel root parasitic plant germination inhibitor. Also provided is a root parasitic plant control agent comprising the root parasitic plant germination inhibitor. Further provided is a method for controlling a root parasiti...  
WO/2013/140506A1
Provided is a method for manufacturing 4,4'-oxydiphthalic acid with favorable productivity and high-yield via 4,4'-oxydiphthalonitrile, using 4-nitrophthalonitrile as a reaction raw material; the method including a hydrolysis step for hy...  
WO/2013/142873A3
The invention provides a novel, general, and facile strategy for the creation of small molecules with high structural and stereochemical complexity. Aspects of the methods include ring system distortion reactions that are systematically ...  
WO/2013/140347A1
Sulphonamide derivatives of benzylamine of formula (I), wherein A represents phenyl unsubstituted or substituted;or 9-or 10-membered bicyclic group, linked to –(O) x - (CH 2 ) y -through one of its aromatic carbon atoms,consisting of b...  
WO/2013/138243A1
The present disclosure encompasses bifunctional compounds resulting from the ring-expanding mono- and bis-carbonylation of glycidyl acrylates to afford the corresponding beta lactones and succinic anhydrides. Uses of the materials and po...  
WO/2013/138153A1
A process is disclosed for making dehydration products from an aqueous sugars solution including pentoses, hexoses or both, for example, an aqeous high fructose corn syrup solution, or from an aqueous solution of one or more of the alcoh...  
WO/2013/136294A1
A complex formed of at least one molecule of 5-(1,2-dihydroxy-ethyl) -3,4-dihydroxy-5H-furan-2-one or a derivative covalently bonded with at least one hydrocarbon radical with formula (A) as follows: wherein: • - m 1 = 1, 2, 3, 4, 5 or...  
WO/2013/138600A1
Radioprotector compounds including 3,3'-diindolylmethane (DIM) analogs, are provided. Further provided are methods for their use in reducing or preventing radiation damage, killing a tumor cell and protecting a non-tumor cell, and treati...  
WO/2013/136030A3
The present invention relates to powder compositions of a complex between an acid or a corresponding anion and at least one metal or corresponding metal cation, said corresponding anion or acid being selected from the group containing 2-...  
WO/2013/135869A1
The invention relates to a process for the preparation of optically active 1,2-diol of formula (S,S)-(I), or alternatively of formula (R,R)-(I) by asymmetric transfer hydrogenation of a compound of formula (II), or a compound of formula ...  
WO/2013/132262A1
The present invention is directed to new compounds of formula (I) as well as to pharmaceutically acceptable salts thereof, to a pharmaceutical composition comprising said compounds, and to the use of said compounds in therapy, and more p...  
WO/2013/133078A1
A polymer characterized by containing repeating units respectively represented by formulae [1a], [1b] and [1c]. The polymer enables the production of a single-layer-coated horizontally oriented film by a simple process. [In the formulae,...  
WO/2013/133208A1
The present invention is a method for producing a tetrahydrofuran compound represented by general formula (2), the method comprising a reaction step for bringing a furan compound represented by general formula (1) into contact with a pal...  
WO/2013/133489A1
A method for producing 5-hydroxymethyl-2-furfural (HMF) from maize syrup containing fructose comprises a conversion step in which a reaction product containing the 5-hydroxymethyl-2-furfural is produced by mixing and heating the maize sy...  
WO/2013/128378A1
The present invention relates to phenyl alkanoic acid derivatives (the compounds of Formula (I)); and their isotopic forms, stereoisomeric and tautomeric forms and mixtures thereof in all ratios, or pharmaceutically acceptable salts, pha...  
WO/2013/128294A8
The invention relates to a novel process for preparation of dronedarone of formula (I) and pharmaceutically acceptable salts thereof, characterized in that a compound of formula (II) - where L is leaving group - is reacted with compound ...  
WO/2013/128294A3
The invention relates to a novel process for preparation of dronedarone of formula (I) and pharmaceutically acceptable salts thereof, characterized in that a compound of formula (II) - where L is leaving group - is reacted with compound ...  
WO/2013/130958A1
The present invention relates to novel benzofuran-2-sulfonamide derivatives formula (I), processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of chemokine receptors.  
WO/2013/124745A1
The invention relates to a novel process for the preparation of dronedarone (I) and pharmaceutically acceptable salts thereof (formula I), which comprises oxidizing a compound of formula (VI), or a salt thereof and the obtained product i...  
WO/2013/124745A9
The invention relates to a novel process for the preparation of dronedarone (I) and pharmaceutically acceptable salts thereof (formula I), which comprises oxidizing a compound of formula (VI), or a salt thereof and the obtained product i...  
WO/2013/125732A1
The present invention provides a compound having a GOAT inhibitory action, which is useful for the prophylaxis or treatment of obesity and the like, and has superior efficacy. The present invention is a compound represented by the formul...  
WO/2013/125211A1
The purpose of the present invention is to provide an optical film that produces a large amount of in-plane retardation and sufficient reverse wavelength dispersion even with a low film thickness. This optical film contains a thermoplast...  
WO/2013/125599A1
[Problem] To provide an organic compound which is easy to synthesize and has excellent chemical stability, semiconducting properties (high carrier mobility) and high solubility in a solvent. [Solution] A compound represented by formula (...  
WO/2013/122905A1
A method of making acid anhydrides from epoxide and carbon monoxide feedstocks is presented. In various aspects, the method includes steps of reacting the contents of a feed stream comprising an epoxide, a solvent, a carbonylation cataly...  
WO/2013/121235A2
The invention relates to a novel process for preparation of dronedarone of formula (I) and pharmaceutically acceptable salts thereof the hydroxyl group is removed, and the obtained product is isolated and, if desired, converted into a ph...  
WO/2013/121209A1
A compound of formula I, and its pharmaceutically acceptable salt or salts and physiologically hydrolysable derivatives in free form or salt form: (Formula (I)) wherein either Q1, CR6a and optionally R6b together form a cyclic moiety whe...  

Matches 301 - 350 out of 28,430