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Matches 301 - 350 out of 29,366

Document Document Title
WO/2014/197991A8
The present application describes amphiphatic compounds like compound Ila below, compositions and methods for incorporating chemoselective and bio-orthogonal complementary functional groups into liposomes. Such compounds are incorporated...  
WO/2014/198123A1
The present invention relates to the field of natural pharmaceutical chemistry, specifically to a resveratrol dimer, (7R, 8R)-trans-delta-viniferin (I), a preparation method therefor and the use thereof in reducing blood sugar. High-spee...  
WO/2014/198057A1
Disclosed is a process for the production of furanic compound comprising at least one amine function, comprising reacting a furanic compound having at least one hydroxyl function or at least one aldehyde function with a second reactant h...  
WO/2014/199306A3
A process is described for the preparation of 5-hydroxymethylfurfural (HMF), which comprises the following steps: provision or preparation of a starting mixture, comprising one, two or more starting compounds selected from the group cons...  
WO/2014/197991A1
The present application describes amphiphatic compounds like compound Ila below, compositions and methods for incorporating chemoselective and bio-orthogonal complementary functional groups into liposomes. Such compounds are incorporated...  
WO/2014/196491A1
[Problem] To provide a method for producing a (2R)-2-fluoro-2-C-methyl-D-ribono-γ-lactone. [Solution] A 2-fluoro-2-halopropionic acid derivative and a D-glyceraldehyde derivative are subjected to a Reformatsky reaction using an activate...  
WO/2014/195972A1
A regioselective N-Heterocyclic Carbene (NHC) catalyzed one step process for high yield synthesis of α-acyloxy carbonyl compounds is disclosed.  
WO/2014/194957A1
The present invention relates to new compounds according to formula (I). Said compounds are particularly useful for the improvement of organic electronic devices where the compounds according to the present invention are used e.g. as dop...  
WO/2014/197514A1
The present disclosure generally relates to the production of fuels, gasoline additives, and/or lubricants, and precursors thereof. The compounds used to produce the fuels, gasoline additives, and/or lubricants, and precursors thereof ma...  
WO/2014/194292A1
Disclosed herein are compounds and methods of using such compounds for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases o...  
WO/2014/192023A1
The present invention relates to compounds of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use ...  
WO/2014/193033A1
The present invention relates to a compound, an organic light emitting element comprising the same, and a display device comprising the organic light emitting element. The present invention provides a compound for an organic optoelectron...  
WO/2014/193635A1
Plasticizers comprising a dialkyl 2,5-furandicarboxylate and plasticized polymeric compositions comprising such plasticizers. Such plasticized polymeric compositions can be employed in forming various articles of manufacture, such as coa...  
WO/2014/194209A1
Disclosed herein are compounds having a formula: or a pharmaceutically acceptable salt thereof, as well as therapeutic methods, medicaments, and compositions related thereto.  
WO/2014/188843A1
The purpose of the present invention is to provide a method for producing tetrahydrofuran with high reaction yield using erythritol that is a biomass or 3,4-dihydroxytetrahydrofuran that can be induced readily from erythritol as a raw ma...  
WO/2014/187343A1
Disclosed are a benzofuran derivative, a preparation method therefor, and a medical application thereof, specifically relating to a compound represented by general formula (I), a stereoisomer thereof, a hydrate thereof, a solvate thereof...  
WO/2014/188762A1
The present invention is a radiation-sensitive resin composition which contains a polymer having a structural unit that contains an acid-cleavable group and a compound represented by formula (1). In formula (1), R1 represents a monovalen...  
WO/2014/184682A9
Provided herein is technology relating to imaging agents for positron emission tomography (PET) and particularly, but not exclusively, to a gonadotropin-releasing hormone (GnRH) antagonist radiolabeled with positron emitting nuclides and...  
WO/2014/184682A1
Provided herein is technology relating to imaging agents for positron emission tomography (PET) and particularly, but not exclusively, to a gonadotropin-releasing hormone (GnRH) antagonist radiolabeled with positron emitting nuclides and...  
WO/2014/183211A1
Discloses is a process for preparation of a compound of formula 11, or a derivative thereof, wherein PG1 is an alcohol protecting group. Also, disclosed are intermediates and processes for their preparation. The compound of formula 11 ca...  
WO/2014/186035A1
The present application provides novel inhibitors of indoleamine 2,3-dioxygenase-1 and/or indoleamine 2,3-dioxygenase-2 and/or tryptophan 2,3-dioxygenase, metabolites thereof, and phannaceutically acceptable salts or prodrugs thereof. Al...  
WO/2014/182688A1
The present invention relates to compounds of Formula (Ia) and pharmaceutically acceptable salts, solvates, and hydrates thereof, that modulate the activity of the Mas receptor, and are useful in methods of treatment and alleviation of d...  
WO/2014/180979A9
This invention relates to a new process for the synthesis of 5-hydroxymethylfurfural (HMF) from saccharides. In particular this invention relates to a new process for the dehydration of monosaccharides having 6 carbon atoms (hexoses), di...  
WO/2014/180979A1
This invention relates to a new process for the synthesis of 5-hydroxymethylfurfural (HMF) from saccharides. In particular this invention relates to a new process for the dehydration of monosaccharides having 6 carbon atoms (hexoses), di...  
WO/2014/180271A1
Revealed in the present invention is a method for preparing Afatinib (I): using 2-nitrile-4-[4-(N,N-dimethylamino)-1-oxo-2-buten-1-yl]amino- 5-[(S)- (tetrahydrofuran-3-yl)oxy]aniline (II) and 4-fluoro-3-chloroaniline (III) as starting ma...  
WO/2014/182244A1
The present invention provides a polymer comprising an aliphatic backbone having a plurality of aromatic rings bonded thereon, said plurality of aromatic rings comprising a first aromatic ring type that has an alkyl halide group substitu...  
WO/2014/182873A1
The present disclosure provides novel furanone compounds, or pharmaceutically acceptable salts, solvates or prodrugs thereof, as Raf kinase, especially BRAF kinase, inhibitors, which are useful therapeutic agents for treatment of Raf kin...  
WO/2014/181788A1
The present invention provides: a novel α-substituted glycineamide derivative or a pharmacologically acceptable salt thereof; a pharmaceutical composition containing the α-substituted glycineamide derivative or a pharmacologically acce...  
WO/2014/182171A1
Disclosed is a method of making 5-formyl-2-furoic acid and furan- 2,5-dicarboxylic acid. The method involves the use of 5-keto-aldonic acids as intermediates, as these can be subjected to ring formation by a cyclodehydration reaction und...  
WO/2014/182673A1
The present invention relates to compounds of Formula (la) and pharmaceutically acceptable salts, solvates, and hydrates thereof, that modulate the activity of the Mas receptor, and are useful in methods of treatment and alleviation of d...  
WO/2014/179156A1
5-(hydroxymethyl) furan-2-carbaldehyde (HMF)-sulfonates and a method of preparing the same are described. The method involves reacting a mixture of 5-(hydroxymethyl)furfural (HMF), with at least one of a) a trifluoromethanesulfonate anhy...  
WO/2014/177593A1
The present invention relates to Amorfrutin analogues and stereoisomeric forms, solvates, hydrates, conjugates and/or pharmaceutically acceptable salts of these compounds as well as pharmaceutical compositions containing at least one of ...  
WO/2014/178389A1
Provided is a new compound having glycogen synthase activation potency, high muscular transition, minimal activation of receptor PPAR, and a high degree of safety. Provided is a compound represented by the following general formula, or a...  
WO/2014/178381A1
 Provided is a new compound having glycogen synthase activation potency, but minimal activation of receptor PPAR, and a high degree of safety. A compound represented by general formula [I], or a pharmaceutically acceptable salt there...  
WO/2014/177464A3
The invention relates to inhibitors of the NHR2 tetramerization and their use as tumor therapeutics (e.g. against acute myeloid leukemia (AML)), cytostatics, and diagnostic agents.  
WO/2014/174416A3
A method of dehydration of at least one compound (A) comprising, in the chain form, -at least one hydroxyl group and -at least one carbonyl functionality selected from the group consisting of aldehyde (CHO), ke- tone (CO) and carboxylic ...  
WO/2014/173973A1
The invention provides a process for the preparation of monoethylene glycol from sucrose comprising the steps of: i) hydrolysing sucrose to form a reaction product stream comprising glucose and fructose; ii) separating the reaction produ...  
WO/2014/176151A1
The present application relates to perfume delivery systems and consumer products comprising such perfume delivery systems, as well as processes for making and using such perfume delivery systems and consumer products. Such perfume deliv...  
WO/2014/175713A1
The present invention relates to a pharmaceutical composition comprising a 5-membered heterocyclic compound, having an analgesic effect, and a derivative thereof. More particularly, the present invention relates to a preparation method f...  
WO/2014/170909A3
The present invention provides a novel process for the preparation of pomalidomide crystalline Form I. The present invention also provides a process for the purification of pomalidomide.  
WO/2014/172363A3
The present invention relates novel heterocyclic analogs of combretastatin, their synthesis, and their use as anti-cancer compounds. In particular, compounds of Formula (I), Formula (II), and Formula (V) are provided.  
WO/2014/167108A1
The invention relates to tetrahydrofuran derivatives of general formula (I), wherein X stands for ⋆-(C=O)-O-, ⋆-(CH2)n-O-, or ⋆-(CH2)n-O-(C=O)-, wherein * represents the point of bonding to the tetrahydrofuran ring and n has the va...  
WO/2014/169214A1
This invention provides processes to convert biomass, including wood and agricultural residues, to levulinic acid and co-products. Some variations treat feedstock with steam and/or hot water to produce an extract liquor containing hemice...  
WO/2014/165827A1
Provided herein are compounds and compositions useful in increasing PPARδ activity. The compounds and compositions provided herein are useful for the treatment of PPARδ related diseases (e.g., muscular diseases, vascular disease, demye...  
WO/2014/163500A1
2,5-Furandicarboxylic acid and methyl acetate are prepared in a continuous process, comprising -introducing a 5-methoxymethylfurfural-containing feedstock, an oxygen-containing gas, an oxidation catalyst and an acetic acid-containing sol...  
WO/2014/157574A1
Provided are: a new material useful as an organic electroluminescent element material, namely a condensed fluoranthene compound having a heteroatom on an indeno[3,2-b] fluoranthene backbone; a material for an organic electroluminescent e...  
WO/2014/159559A1
The disclosure provides compounds of formula I or II, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infe...  
WO/2014/158838A1
A process is described for converting HMF to FDCA, comprising dissolving a quantity of HMF in water to form an aqueous solution including HMF, combining the aqueous solution including HMF with an oxygen source in the presence of a homoge...  
WO/2014/155291A1
The invention provides processes for the manufacture of a compound of formula (IA ). The invention further provides improved methods for the conversion of the compound of formula (I A ) into pregabalin.  
WO/2014/159802A1
The present invention provides compounds of Formula (I) or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR120 G protein-coupled receptor modulator...  

Matches 301 - 350 out of 29,366