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Matches 1 - 50 out of 14,179

Document Document Title
WO/2018/009861A1
The present invention provides fluorescent polyfluorene polymers or macromers with unique optical properties that are stable. The polymeric fluorophores are useful in various bioassays formats. The inventive polymers are useful in assays...  
WO/2018/000093A1
A composition for facilitating eyelash and/or eyebrow growth which includes at least forskolin derived exclusively from coleus forskohlii and at least one keratmocyte growth stimulator. In some embodiments, the keratinocyte growth stimul...  
WO/2017/221002A1
The present invention relates to a novel class of chromene-2-carboxamide compounds inhibitors of general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8 and X are as defined herein, to their use in medicine, and their use as anti-infe...  
WO/2017/221269A1
The present invention pertains to the enhanced activity of (+) epicatechin over (-) epicatechin. The present invention is related to novel analogs of (+) epicatechin of the formula (I), which enhances the pharmacokinetics and therefore t...  
WO/2017/216699A1
Subject-matter of the present invention are novel 3-ketocoumarins, a process for their preparation and their use as photoinitiators in photopolymerization reactions, advantageously in photopolymerization reactions for inkjet printing ink...  
WO/2017/216362A1
Described are methods for producing cannabinoid prodrugs using enzyme-catalysed synthesis / chemical modifications as well as methods for formulating such prodrugs in a pharmaceutically acceptable form and their use as therapeutic agents...  
WO/2017/215680A2
Disclosed are a chlorprothixene pharmaceutical composition and effects thereof for protecting cerebral ischemia reperfusion injuries. The chlorprothixene pharmaceutical composition provided in the present invention comprises chlorprothix...  
WO/2017/215538A1
Provided are a Mannich base derivative of acetylchrysin having a structrue of general formula I and a use thereof, wherein R1 and R2 are each independently selected from an acetyl and organic secondary amine methylene, and only one of R1...  
WO/2017/216426A1
The invention relates to process for converting berry and/or fruit materials to fractions comprising bioactive compounds, said process comprising the steps, where at least one berry material or fruit material selected from berries, fruit...  
WO/2017/212059A1
The present invention relates to a new process of manufacturing of caged cyclofen-OH and derivatives thereof, of formula (I) or salts thereof, wherein n, R1, R1 ', R2, and R3 are as defined in the claims.  
WO/2017/214529A1
This disclosure relates to techniques and methods to isolate and purify cannabinoids, such as CBDV, CBD, CBC, THCV, THC, CBN, CBG, CBDA, THCA, or CBGA. Evaporation and sonicating techniques are used to isolate and purify cannabinoids, su...  
WO/2017/207539A1
The invention relates to tetrahydropyranyl lower alkyl esters and particularly tetrahydropyranyl acetates, a method for producing same using ketene, and the use of same as fragrant and aromatic substances.  
WO/2017/202798A1
The present invention provides novel compounds having the general formula (I) wherein R1 to R6, X, Y, A1 and A2 are as described herein, compositions including the compounds and methods of using the compounds.  
WO/2017/205350A1
Molecular probes for detecting and imaging pancreatic cancer are disclosed. The probes are modified benzoxanthene fluorophores, which are selectively taken up by pancreatic cancer cells, such as pancreatic ductal adenocarcinoma cells. Em...  
WO/2017/201581A1
The present invention relates to new desferrioxamine B-based compounds that may be useful to treat neurodegenerative diseases, to their preparation, and to compositions including the compounds. The present invention also relates to the u...  
WO/2017/201531A1
Provided are a photoactive fluorophore, a photoactive ligand, and a photoactive complex. The photoactive fluorophore includes a photoactivatable derivative of an azetidine-containing Janelia-Fluor dye. The photoactive ligand includes a p...  
WO/2017/195835A1
One purpose of the invention is to provide a technique for modifying polyphenols to suppress the occurrence of precipitation and turbidity in water without separate addition of food additives or conducting enzyme treatment. Modified poly...  
WO/2017/194173A1
The present invention relates to methods for purifying one or two cannabinoid compounds using simulated moving bed chromatography, wherein the cannabinoid compound(s) is/are obtained in the extract and/or the raffinate with the total amo...  
WO/2017/187321A1
The present invention provides for compounds of formula (I), wherein R1, m, Z, G1, R2, and R3 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment ...  
WO/2017/185179A1
A method of increasing the self-renewal and/or expansion of hematopoietic stem and/or progenitor cells (HSPCs) is described. Inhibiting the activity and/or expression of cytochrome P450 1B1 (CYP1B1) and/or increasing the expression or ac...  
WO/2017/184623A1
In one aspect, compounds of Formulae (I) and (II), or pharmaceutically acceptable salts thereof, are featured: Formulae (I) and (II), wherein the variables shown in Formulae (I) and (II) can be as defined anywhere herein.  
WO/2017/184498A1
Processes for preparing compositions comprising substituted 1,2-dihydroquinolines and having low or undetectable levels of substituted anilines, wherein the processes comprise removing the substituted anilines from feed streams comprisin...  
WO/2017/177919A1
Provided in the present invention is a compound as shown in formula (I), formula (II) or formula (III). The compound is capable of inhibiting the binding of the PB2 protein of the influenza virus to an RNA cap, and has a function of oppo...  
WO/2017/181118A1
The present invention provides methods for producing cannabinoid prodrugs. Also described are pharmaceutically acceptable compositions of the prodrugs and a system for the large-scale production of the prodrugs.  
WO/2017/177004A8
Compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein G1, G2, G3, L1, L2, and L3 are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by the modulation ...  
WO/2017/175064A1
A method for the bio-enzymatic synthesis of tetrahydrocannabivarin (THC-v), cannabivarin (CBV) and cannabinol (CBN) by contacting a compound according to Formula I with a cannabinoid synthase enzyme. The cannabinoids are produced in the ...  
WO/2017/177004A1
Compunds of Formula (I) and pharmaceutically acceptable salts thereof, wherein G1, G2, G3, L1, L2, and L3 are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by the modulation o...  
WO/2017/156520A1
Disclosed are derivatives of icariin. Disclosed are compounds having Formula I-V as defined herein. Methods of using these compounds for the treatment of cancer and inflammation are also disclosed.  
WO/2017/152539A1
Provided are a 4-sulfur pentafluoride phenol compound and a preparation method therefor, and a preparation method for a sulfur pentafluoride substituted benzopyran compound. According to the present invention, sulfur pentafluoride salicy...  
WO/2017/146400A1
The present invention relates to a compound for detecting phosgene and DCP (diethyl chlorophosphate) and a composition for detecting phosgene and DCP (diethyl chlorophosphate) comprising the said compound. More precisely, the compound fo...  
WO/2017/146466A1
The present specification relates to a heterocyclic compound and an organic light emitting element comprising the same.  
WO/2017/139962A1
A method for extracting herbacetin from rhodiola rosea comprises the steps of: 1) extracting a medicinal material by using an extraction solvent, and then concentrating to obtain an extract paste; 2) extracting the extract paste, and aci...  
WO/2017/135286A1
Provided are an urolithins-containing aqueous solution comprising urolithins and collagen, a dried solid composition thereof, and a production method therefor, and an urolithins stabilizing method.  
WO/2017/132775A1
This invention provides novel compositions and methods for the treatment of leiomyoma. In some other aspects, this invention provides novel compositions and methods comprising prodrugs of (-)-epigallocatechin-3-gallate (EGCG) and prodrug...  
WO/2017/131047A1
The presentt invention addresses the problem of providing a photocuring method that obtains a crosslinked product (resin) quickly and efficiently, a compound used in the photocuring method, and a photocurable resin composition containing...  
WO/2017/125900A1
The present invention relates to a novel process for the synthesis of the intermediate compounds constituted by chromanyl haloketones of formula III and 6-fluoro-2-(oxiran-2-yl) chromans of formula I. The intermediates thus obtained can ...  
WO/2017/125638A1
The invention relates to a method for the fluorescence-based determination of tertiary amines by means of reactants that use halogenated-xanthene-based dyes. The invention also relates to a kit comprising the reactants necessary for carr...  
WO/2017/124949A1
The present invention relates to flavanone derivatives and a preparation method and use thereof, and in particular relates to the compound as shown in formula (I) or a pharmaceutically acceptable salt thereof, or a pharmaceutical composi...  
WO/2017/121855A1
The present invention relates to compounds of formula (I) These compounds are useful in the treatment of many diseases such as a skin disease, an allergy, an autoimmune disease, a cardiovascular disease, a lung disease, asthma, a bacteri...  
WO/2017/122722A1
The present invention provides: a compound represented by formula (1) as a pharmaceutical agent which is useful as a neuroregeneration promoting agent [in the formula, R1-L- represents R1-OC(O)-, etc., R1 represents a hydrogen atom, an o...  
WO/2017/120591A1
The present disclosure provide a combination of a chromene compound having the structure of Formula (I), or pharmaceutically acceptable salts, and a second compound that can be selected from a PD-1 inhibitor, PD-L1 inhibitor, CTLA-4 inhi...  
WO/2017/113013A1
The present disclosure provides biophotonic topical compositions, kits and their uses. In some aspects, the biophotonic topical compositions of the present disclosure comprise a first chromophore, a salt selected from one or more bicarbo...  
WO/2017/111387A1
The present invention relates to a pseudo-ceramide compound and a preparation method therefor. The pseudo-ceramide compound of the present invention can provide an antioxidative effect, and can exhibit improved physical properties, such ...  
WO/2017/111076A1
The invention provides an α,β unsaturated amide compound having anticancer activity shown by formula (I) or a pharmaceutically acceptable salt or the like thereof: [in the formula, A represents an optionally substituted heterocyclic di...  
WO/2017/100882A1
This invention patent relates, in a first aspect, to cell staining compositions comprising a mixture of dyes or salts and complexes thereof in an aqueous medium and optionally a cell lysis agent. Also disclosed are methods for preparing ...  
WO/2017/106786A1
Provided herein are methods for making an alpha-tocotrienol enriched tocol mixture, such as from a plant or plant-derived material. Also provided herein are simulated moving bed purification methods for tocotrienol compounds such as alph...  
WO/2017/103840A1
The embodiments herein provides method for synthesizing water soluble forskolin 10% w/w. 250 litres of distilled water, 5 kg of pre-treated forskolin (98% w/w) and 20 kg of synthetic water soluble polymer are added into the reactor to ob...  
WO/2017/103931A1
Compounds capable of, or usable in, killing cancer cells, and/or modulating a biological activity of a chemokine, and/or inhibiting a kinase, and/or treating diseases and disorders associated with a biological activity of a chemokine and...  
WO/2017/106649A1
This disclosure is related to methods for producing anhydroryanodol, ryanodol, or analogues thereof and novel compounds prepared thereby.  
WO/2017/105041A1
The present invention relates to a novel compound and an organic electroluminescent device comprising the same. The compound according to the present invention is used for an organic material layer of an organic electroluminescent device...  

Matches 1 - 50 out of 14,179