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Matches 1 - 50 out of 2,329

Document Document Title
WO/2018/197963A1
The invention relates to a method for the preparation of cyclic compounds in the metathesis of olefins from acyclic dienes comprising terminal and/or non-terminal C=C double bonds; the invention also relates to the use of homogeneous rut...  
WO/2018/175418A1
16-membered macrolide compounds inhibit growth of various microbial species and have utility in the treatment of systemic or topical microbial infections, including methicillin-resistant strains (Formula I).  
WO/2018/150421A1
The invention provides efficient cyclization processes of hydroxyalkenoic acids and products produced therefrom. The following reactions are claimed: Formula (I), (II), (V) and (VI).  
WO/2018/100515A1
The invention relates to novel ruthenium complexes of formula (9). The invention also relates to the method for preparation of novel metal complexes of formula (9) and their use in olefin metathesis reactions.  
WO/2018/084120A1
A benzoic acid derivative and a dehydration-condensation agent, each of which is represented by formula (I) or (II). In formulae (I) and (II), R1 represents a haloalkyl group, a halogen atom or a cyano group; and R2, R3 and R4 independen...  
WO/2018/063049A1
Disclosed is an equipment and a process for processing of a product stream (a) comprising acetic acid, unreacted cyclohexanone, reaction water and organic heavy ends, said product stream (a) being yielded in a caprolactone production whe...  
WO/2018/049733A1
A method for preparing ε-caprolactone is provided. The method comprises the following steps: adding a cyclohexanone, an auxiliary oxidant, a certain amount of catalyst and a molecular oxygen as an oxidant into a certain amount of organi...  
WO/2018/003945A1
[Problem] Provided are a method for producing 2-propanil 4-{(3S,5aR,6R,7R,8aS)-6-[(1E,3R)-4-(2,5-difluorophenoxy)-3-h ydroxy-1-butene-1-yl]-7-hydroxyoctahydro-2H-cyclopenta[b]oxe pine-3-yl}butanoate, which can solve various problems desc...  
WO/2017/184984A1
Molecular characterization of disease has become the dominant trend in modern medicine, and it has recently become increasingly important to obtain qPCR, microarray, and next-generation sequencing (NGS) data for both research and clinica...  
WO/2017/160925A1
Disclosed herein are compounds of Formulae (I), and (II), methods of synthesizing compounds of Formulae (I) and (II), and methods of using compounds of Formulae (I) and (II) as an analgesic.  
WO/2017/153455A1
A process for preparing a macrocyclic lactone comprising 14 to 17 ring carbon atoms, the process comprising the steps of i) subjecting a reaction mixture comprising an olefin-containing random polyester, formed by metathesis to a cyclo-d...  
WO/2017/155442A1
Disclosed is a production equipment for production of a caprolactone by reaction between peracetic acid, produced from acetic acid and hydrogen peroxide, and cyclohexanone, said equipment being split into a first section (Fig. 1) wherein...  
WO/2017/155441A1
Disclosed is a production equipment for production of a caprolactone by reaction between peracetic acid, produced from acetic acid and hydrogen peroxide, and cyclohexanone, said equipment being split into a first section (Fig. 1) wherein...  
WO/2017/152099A1
The instant invention describes macrocyclic compounds having therapeutic activity, and methods of treating disorders such as methods of modulating immune response processes, and methods of treating disease, disorders, and symptoms thereof.  
WO/2017/124184A1
The present invention provides a new compound of formula (I): extracted from a seaweed, and its use for inhibiting the growth of cancer cells, as well as methods for its extraction and isolation.  
WO/2017/118375A1
Disclosed in the present invention is a Dezocine analogue, and particularly disclosed are compounds represented by formula (I), (II) and (III), a pharmaceutically acceptable salt or tautomer thereof.  
WO/2017/116939A1
The invention relates to macrocyclic picolinamides of Formula (I) and their use as fungicides. (Formula (I))  
WO/2017/116954A1
The invention relates to macrocyclic picolinamides of Formula (I) and their use as fungicides.  
WO/2017/116956A1
This disclosure relates to macrocyclic picolinamides of Formula (I) and their use as fungicides.  
WO/2017/080292A1
A trifluoromethyl-modified (+)-Patulolide C. By adding a trifluoromethyl group to (+)-Patulolide C, it is expected that favorable antibacterial and anti-inflammatory activity can be obtained.  
WO/2017/040769A1
Compositions and methods for the production of derivatives of spinosyns are provided. The method produces spinosyn derivatives that exhibit activity towards insects, arachnids, and/or nematodes and are useful in the agricultural and anim...  
WO/2017/040763A1
Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include spinosyn derivatives functionalized on the C5-C6 double bond of th...  
WO/2017/040878A1
Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include those functionalized on the C-13,14 double bond to provide an addi...  
WO/2017/040882A1
Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include spinosyn derivatives functionalized on the C5-C6 double bond of sp...  
WO/2017/030450A1
A method of increasing the rigidity of PIM homo- or co-polymers including repeating units containing at least one biscatechol monomer having a fused spiro-bisindane (SBI) ring system of Formula (I), the SBI ring system including a bicycl...  
WO/2017/026643A1
The present disclosure relates to an organic electroluminescent compound and an organic electroluminescent device comprising the same. The organic electroluminescent compound of the present disclosure is effective in preparing an organic...  
WO/2017/019561A1
A compound having the structure (I) and (II).  
WO/2017/019550A1
A compound having the structure (I) or (II).  
WO/2016/193134A1
The invention relates to a method for producing cyclic esters of general formula (I.a) or (I.b) in the presence of at least one high-boiling metal alkoxide catalyst. The invention further relates to the stereoisomers of 18-methyl-1-oxacy...  
WO/2016/196256A2
This disclosure is directed to non-aromatic difluoro analogues of resorcylic acid lactones, pharmaceutical compositions comprising non-aromatic difluoro analogues of resorcylic acid lactones, and methods of treatment comprising non-aroma...  
WO/2016/196256A3
This disclosure is directed to non-aromatic difluoro analogues of resorcylic acid lactones, pharmaceutical compositions comprising non-aromatic difluoro analogues of resorcylic acid lactones, and methods of treatment comprising non-aroma...  
WO/2016/167698A1
Disclosed is a catalysed Baeyer-Villiger oxidation of cyclic ketones yielding corresponding lactones. Hydrogen peroxide is used as oxidant and said oxidation is catalysed by a catalytically active amount of at least one catalyst comprisi...  
WO/2016/128991A1
The invention relates to the compounds of formula I, formula II, formula III, formula IV, formula V, formula VI, formula VII and formula VIII, or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates...  
WO/2016/104630A1
The present invention pertains to: a condensed heterocyclic compound having an inhibitory effect on enteropeptidase, the condensed heterocyclic compound being useful in the treatment or prevention of obesity, diabetes, and the like; and ...  
WO/2016/068220A1
Provided are: eushearilides; a method for producing eushearilides; a production intermediate; and a pharmaceutical composition containing eushearilides. By having the Wittig reaction process, Mukaiyama Aldol reaction process and Macrolac...  
WO/2016/019587A1
Provided are compounds of the structural formula (I), the pharmaceutically acceptable salts thereof, and the use as agonists of G-protein coupled receptor 40 (GPR40) for the treatment of Type 2 diabetes mellitus, and of conditions that a...  
WO/2016/018153A1
The present invention relates to novel compounds, comprising an 8-or 9- membered cyclic structure, wherein an (E)-1,4-dioxo-but-2-ene moiety is embedded in said cyclic structure and to pharmaceutical compositions comprising these compoun...  
WO/2016/014797A1
The invention relates to novel compounds and pharmaceutical preparations thereof, as well as methods of making and using these compounds. The invention further relates to methods of treating or preventing disease using the novel compound...  
WO/2016/005049A1
The present invention relates to a compound according to general formula (I), which exhibits bioactivity; methods for the production of the compound; to pharmaceutical compositions comprising one or more of the compound(s); and to the us...  
WO/2015/145152A1
The invention providesnovel macrolide compounds of formula (I) and their pharmaceutically acceptable salts, metabolites, isomers (e.g. stereoisomers), and prodrugs. In formula (I), R1 is hydrogen or an ester-forming group; R2 is methyl o...  
WO/2015/082046A3
The invention relates to materials, to electroluminescence devices comprising said materials and to the use thereof.  
WO/2015/083185A1
The present invention discloses an improved oxidation process using carbon nitride nanotubes as metal free catalyst and molecular O2 as the oxidant to obtain desired adipic acid and other oxygenated hydrocarbons with improved conversion ...  
WO/2015/082046A2
The invention relates to materials, to electroluminescence devices comprising said materials and to the use thereof.  
WO/2015/079009A1
The present invention provides new therapeutic compounds for treatment of diseases caused or influenced by microtubule stability, such as proliferative diseases. The compounds are phenyl-analogs of the naturally occurring peloruside. The...  
WO/2015/067657A1
A process for the oxidation of an organic carbonyl compound comprising reacting the compound, optionally in the presence of a solvent, with hydrogen peroxide in the presence of a catalyst comprising a tin-containing zeolitic material and...  
WO/2015/067654A1
A process for preparing a tin-containing zeolitic material having a BEA framework structure comprising providing a zeolitic material having a BEA framework structure having vacant tetrahedral framework sites, providing a tin-ion source i...  
WO/2015/063579A1
The present invention refers to a new "one-pot" process for the preparation of olopatadine via intermediates of formula (III).  
WO/2015/063579A8
The present invention refers to a new "one-pot" process for the preparation of olopatadine via intermediates of formula (III).  
WO/2015/033261A1
The present application provides a catalytic process which involves the cyclization of a novel catalytic intramolecular arylation process that involves boronic acid or ester aldehydes or imines substrates, of formula (I) and (II), to aff...  
WO/2015/006535A3
Dictyostatin derivatives and prodrugs, as CNS-active MT-stabilizing agents are disclosed as alternative and potentially improved clinica candidates for the treatment of cancer in a subject, and methods of treating diseases using them, ar...  

Matches 1 - 50 out of 2,329