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WO/2014/057500A1 |
This invention discloses one step transition metal free process for synthesis of cyclic carbonates from aldehydes and carbon dioxide. More particularly, the invention relates to single step procedure involving Corey-Chaykovsky reaction a...
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WO/2014/056937A1 |
Provided are methods for purifying fluorinated organic carbonates, especially fluoroethylene carbonates produced from the reaction of ethylene carbonate and elemental fluorine. The methods according to the present invention comprise a st...
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WO/2014/058078A1 |
Disclosed is a process for preparing dihydro-2H-pyran derivatives of formula I: wherein R1 and R2 are defined herein. The process of the invention provides the compound of formula I in concise cascade reactions and in one pot. The compou...
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WO/2014/056936A1 |
A process for the preparation of purified fluorosubstituted organic carbonates, especially of fluoroethylene carbonate, difluoroethylene carbonate, fluoromethyl methyl carbonate and difluorinated dimethyl carbonate from ethylene carbonat...
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WO/2014/053857A1 |
Disclosed herein are mono or di-succinate compounds where one or both of the acid groups in the succinate core are protected in the form of biologically labile moieties, and the use of said compounds to enhance mitochondrial function. Th...
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WO/2014/053694A1 |
Compounds of formula I, wherein A, B, X, Z and R1-R6, are as defined in the claims, exhibit TRPA 1 activity and are thus useful as TRPA1 modulators.
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WO/2014/044489A1 |
The invention relates to n-pentylester und iso-pentylester with at least one cyclic carbonate group on the acid chain, to a method for the production and use of the ester as a plasticizer fpr polymers.
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WO/2014/034937A1 |
The purpose of the present invention is to provide a practical method for producing a cyclic carbonate, which is widely used for various applications such as electrolytic solutions for lithium-ion secondary batteries and plastic material...
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WO/2014/034936A1 |
The purpose of the present invention is to provide a practical method for producing a cyclic carbonate, which is widely used for various applications such as electrolytic solutions for lithium-ion secondary batteries and plastic material...
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WO/2014/033045A1 |
The invention relates to a method for producing polyurethanes containing cyclic carbonate structures by reacting at least A) a composition containing a) one or more compounds of the general formula (I), said compounds containing isocyana...
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WO/2014/033046A1 |
The invention relates to a process for preparing compounds containing isocyanate groups and cyclic carbonate structures, by reacting at least A) a monomeric diisocyanate with aliphatically, cycloaliphatically, araliphatically and/or arom...
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WO/2014/029713A1 |
The present invention relates to a method for producing linear and/or cyclic carbonate esters, involving the step of reacting an epoxide with carbon dioxide in the presence of a catalyser. The invention further relates to the use of spec...
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WO/2014/027696A1 |
The purpose of the present invention is to provide a compound that is useful as an orally administrable anti-HCV agent. The present invention relates to the compound represented by formula (1) or a pharmaceutically acceptable salt of sai...
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WO/2014/024074A1 |
Compounds of general formula I, II, III and IV: Formula (I) wherein the variables have the meaning given in the description, and a process for the preparation of compounds of general formula I, II, III and IV are disclosed. The use of th...
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WO/2014/020281A1 |
A process for preparing a carboxylic acid, by oxidative cleavage of at least one vicinal diol, or an epoxide, wherein the reaction is carried out in the presence of a catalyst and of an oxidizing agent and in the absence of solvent.
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WO/2014/016766A1 |
The present invention is directed to guanidine derivatives as inhibitors of transient receptor potential canonical channels (TRPC channels), in particular TRPC3 and/or TRPC6 and/or TRPC7 activity, more particularly TRPC6 activity. Also p...
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WO/2014/009421A1 |
The invention relates to a method for producing a compound of formula (I), comprising the reaction, in the presence of a catalytic system comprising a single rare earth oxide or a mixture of rare earth oxides, of an alkyl carbonate or an...
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WO/2009/158026A9 |
The present invention relates to substituted hydrazonamide compounds. The invention further relates to methods of inhibiting the activity of Hsρ90 in a subject in need thereof and methods for treating hyperproliferative disorders, such ...
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WO/2013/190571A1 |
Present invention relates to an improved and commercial process for the preparation of 2-sustituted-2-(6-(substituted)-7-methylbenzo[d][1,3]dioxol-
4-yl)acetic acid derivatives of formula-I [Formula should be inserted here], wherein R1 i...
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WO/2013/190212A1 |
The invention relates to a method for producing chiral peptides using a solvent and a proton donor element, the pKa in water of which is higher than 7, in the presence of a base pertaining to an acid-base pair, the pKa in water of which ...
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WO/2013/187727A1 |
The present invention relates to novel phenylalkyl sulfamate compounds, a method for preventing or treating a disease associated with muscle spasm. The present invention ensures the enhancement of muscle relaxation activity essential for...
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WO/2013/180271A1 |
Provided are a fluorine-containing amino acid prodrug represented by general formula (I) that makes a fluorine-containing amino acid which is a group 2 metabotropic glutamate receptor agonist into a prodrug, or a pharmacologically accept...
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WO/2013/172239A1 |
The present invention is an acid diffusion control agent consisting of at least one compound selected from among the group consisting of a compound represented by formula (1) and a compound represented by formula (2). In formula (1), R2 ...
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WO/2013/170778A1 |
Disclosed are an intermediate IV for preparing ambrisentan, a preparing method of the intermediate, and a preparing method of ambrisentan. The intermediate compound is a compound of S-configuration, and can be directly synthesized into a...
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WO/2013/171641A1 |
The present invention relates to compounds of formula I: in which Y, Y1, Y 4, Y5, Y 6, R1, R2, R3 and R4 are defined in the Summary of the Invention; capable of inhibiting the activity of BCR-ABL1 and mutants thereof. The invention furth...
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WO/2013/168642A1 |
Provided is an industrial production method with which a substituted benzoic acid compound that is useful as a drug or agrichemical intermediate is obtained with high purity and at a high yield. A compound represented by formula (II) (wh...
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WO/2013/169362A1 |
Described herein are inventive methods for synthesis of cyclic carbonates from C02 and epoxide. In some embodiments, the methods are carried out in the presence of a catalyst comprising an electrophilic halogen. In some embodiments, the ...
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WO/2013/168780A1 |
Provided is a method for producing an optically active 1-amino-2-vinylcyclopropane-1-carboxylic acid ester and 2-vinylcyclopropane-1,1-dicarboxylic acid ester, which do not isomerize during a reaction, with an inexpensive and easily obta...
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WO/2013/163892A1 |
Provided is a pyrimidine compound of formula (I) useful as a pharmaceutical intermediate, wherein Q is selected from the following groups: -C(R1R2), -(C=0), -BR3. Also provided are a process for preparing said pyrimidine compound, interm...
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WO/2013/157528A1 |
Provided is a medicinal agent comprising a compound represented by general formula (1), a pharmaceutically acceptable salt of the compound or a solvate of the compound or the pharmaceutically acceptable salt. A compound represented by ge...
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WO/2013/150457A1 |
The object of the present invention relates to a composition that can be used as fuel comprising: at least one hydrocarbon mixture at least one hydrophobic ketal or acetal of glycerine. Said composition can be advantageously used as fuel...
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WO/2013/142935A1 |
The present invention is related to the use of combretastatin derivatives as anti-tumour agents, in particular against leukaemia, colon tumours, glioblastoma, melanoma, prostate carcinoma, ovarian adenocarcinoma and bronchoalveolar lung ...
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WO/2013/144299A1 |
The invention relates to polymerizable alkylidene-1,3-dioxolan-2-ones, to the production thereof, and to the use thereof to produce polymers. The invention further relates to the homopolymers and compolymers that can be obtained by the h...
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WO/2013/146630A1 |
With respect to organic device materials such as light-emitting element materials, this organic device material precursor provides a high-performance organic device, is able to be widely applied in wet processes, and is characterized by ...
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WO/2013/146437A1 |
[Problem] To provide a novel compound that is useful as an agent for preventing/treating cancer. [Solution] One aspect of the present invention provides a compound expressed by the chemical formula (1) or a pharmaceutically permissible s...
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WO/2013/146631A1 |
With respect to organic device materials such as light-emitting element materials, this organic device material precursor has a specific structure, provides a high-performance organic device, and can be widely applied to wet processes.
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WO/2013/140969A1 |
The present invention is a photoresist composition which contains [A] a polymer that has a structural unit (I) containing an acid-cleavable group and a compound (I) that is represented by formula (1). In formula (1), each of R1, R2, R3 a...
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WO/2013/137330A1 |
Provided is a method for producing optically active 1-amino-2-vinylcyclopropane-1-carboxylic acid ester and 2-vinylcyclopropane-1,1-dicarboxylic acid ester, which use an optically active material that can be cheaply and easily obtained a...
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WO/2013/132520A1 |
The present invention discloses a cheaper and practical protocol for the construction of a wide variety of o-cyanocinnamonitrile and their structural analogues that proceeds with good yields in a single step using CuCN as the only reagent.
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WO/2013/129266A1 |
The present invention is a photoresist composition containing a compound represented by formula (1) and a polymer having structural units which include an acid-dissociable group. In formula (1), R1 represents a hydrogen atom or a monoval...
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WO/2013/130147A1 |
A method of forming a cyclic carbonate product is carried out by reacting an alkylene oxide, such as ethylene oxide, with carbon dioxide in the presence of a metal organic framework (MOF) catalyst with less than 0.5 mol% of any potassium...
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WO/2013/130013A1 |
The invention relates to use of compounds represented by the general formula (I) and pharmaceutically acceptable salts thereof, wherein n is an integer from 2 to 5; p is an integer from 0 to 4; R1 is independently selected from the group...
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WO/2013/130170A1 |
Dialkyi carbonate and diol products are prepared in an integrated process. In one embodiment, alkylene oxide is reacted with carbon dioxide in the presence of a non-halide-containing homogeneous carbonation catalyst in a first reaction z...
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WO/2013/123222A1 |
The invention provides processes for preparing intermediates useful for preparing compounds of the formula (IV): or a tautomer or salt thereof, where R1-R5, a, b, X and P2, are as defined in the specification.
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WO/2013/117843A1 |
Cosmetic composition comprising a multifunctional compound, compound and cosmetic treatment method. The invention relates to a cosmetic composition comprising at least one compound of formula (I): (Z)x-(L)w-(A)y in which: -x and y are in...
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WO/2013/117707A1 |
The present invention relates to the use, for affinity purification of an antibody or an fragment of an antibody, of a ligand-substituted matrix comprising a support material and at least one ligand covalently bonded to the support mater...
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WO/2013/113738A1 |
The invention relates to a novel method for producing methylene-1,3-dioxolanes of the general formula (I) in which R1 und R2 have the meanings specified in the description. Methylene-1,3-dioxolanes are important intermediate products in ...
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WO/2013/115486A1 |
The present invention relates to a novel piperine derivative. The present invention provides a pharmaceutical composition or functional food composition which comprises a piperine derivative as an active ingredient, and which is for prev...
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WO/2013/073658A9 |
Provided is a high-yielding, highly selective acetal compound production method which: does not require adding, removing or manufacturing a catalyst; is a method for producing an acetal compound from a liquid mixture (hereinafter, the li...
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WO/2013/107336A1 |
This invention relates to novel therapeutic uses for compounds which are inverse agonists of the H3 receptor. In particular this invention relates to therapeutic use of these compounds in the treatment of Multiple Sclerosis.
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