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Matches 1 - 50 out of 12,100

Document Document Title
WO/2018/236913A1
Small molecule calpain modulator compositions and pharmaceutical compositions can be prepared and used as therapeutic agents. Exemplary compositions include non-macrocyclic a-keto amide derivatives. The therarapeutic agents can be used f...  
WO/2018/233093A1
A system and a process for co-producing dimethyl carbonate and ethylene glycol. The system comprises an interconnected ethylene carbonate preparation unit and an ethylene carbonate alcoholysis unit. The ethylene carbonate preparation uni...  
WO/2018/232407A1
The present invention provides methods, compositions, devices, and kits for treating cystinuria or related disorders, in which tiopronin is administered to a patient according to a modified- release strategy that releases tiopronin in cr...  
WO/2018/228879A1
The present invention relates to a two-stage hydroformylation process for producing pound of the formula (I) and to a process for producing a compound of the formula (V) comprising the two-stage hydroformylation process for producing a c...  
WO/2018/220088A1
Method of making a second olefin using a first olefin, comprising steps (A) and (B): (A) performing a metathesis reaction with the first olefin in the presence of a metal complex configured to catalyse said metathesis reaction; (B) epoxi...  
WO/2018/222444A1
Embodiments of the disclosure relate to methods of selectively depositing organic and hybrid organic/inorganic layers. More particularly, embodiments of the disclosure are directed to methods of modifying hydroxyl terminated surfaces for...  
WO/2018/213938A1
This application pertains to group 5 metal complexes having the structure of Formula I; and their potential utility in catalyzing ╬▒-alkylation of secondary amine-containing moieties.  
WO/2018/213317A1
The present invention provides, among others, compounds of the following formula which can be used as degradable curing agents, methods for preparing the compounds, degradable polymers and reinforced composites, methods for degrading and...  
WO/2018/211952A1
The purpose of the present invention is to provide a method for safely and efficiently producing a carbonate derivative. This carbonate derivative production method is characterized by emitting light in the presence of oxygen to a compos...  
WO/2018/211013A1
Processes and associated reaction systems for the preparation of ethylene carbonate and ethylene glycol from ethylene oxide are provided, particularly processes and associated reaction systems directed to heat integration in the treatmen...  
WO/2018/202535A1
Substituted benzoyl amides and their use as herbicides. The invention relates to benzoyl amides of general formula (I) as herbicides. In formula (I) X, R and Ra represent radicals such as alkyl, cycloalkyl and halogen. Q is a five-member...  
WO/2018/203564A1
Provided is an inhibitor of at least one type of kinase selected from the group consisting of CDK7, CDK4, CDK6, PIM2´ŻĄTSSK3, MST4, NEK6, MAP3K, MST3, DDR1, SPHK1, CaMK1, AurA, BRK, CaMK4, and PIM1, the inhibitor containing, as an active...  
WO/2018/203525A1
The present invention relates to a 5-step process for preparing iosimenol starting from ammonium 3-amino-5-(aminocarbonyl)benzoate which is first converted to 3-amino-5-(aminocarbonyl)-2,4,6-triiodobenzoic acid using sodium iodine dichlo...  
WO/2018/200041A1
A method of treating a subject suffering from a condition characterized by over- expression of Ten-eleven translocation 1 (TET1) is provided, the method including administering to the subject an effective amount of a compound, or a pharm...  
WO/2018/189598A1
Systems and methods for integrated glycerol carbonate and/or urea production. This disclosure pertains to development of a process for production of glycerol carbonate and/or urea from ammonia, carbon dioxide and glycerol. The process in...  
WO/2018/184379A1
The present invention relates to a preparation method for high purity fluoroethylene carbonate. The preparation method comprises the following steps: 1) reacting raw material chloroethylene carbonate with liquid hydrogen fluoride to prod...  
WO/2018/178130A1
The present invention relates to a versatile process for the simultaneous production of biocomponents for fuels such as gasoline and diesel, essentially starting from glycerol of biological origin only, comprising a multiplicity of inter...  
WO/2018/178362A1
The invention concerns a process for producing a five-membered polycycloaliphatic carbonate comprising a step of reacting a suspension of a powdered sugar alcohol within a carbon dioxide source and a catalyst compound which is soluble in...  
WO/2018/174196A1
Provided are: a novel stabilization method for inhibiting temporal alternation of a high-purity ethylene carbonate-containing composition; a stabilized high-purity ethylene carbonate-containing composition; and the like. This method for ...  
WO/2018/162769A3
The invention can be used to double the yield of a Krapcho reaction by means of which oleacein is obtained from oleuropein, present in olive leaves. Oleacein, a dialdehyde secoiridoid present in virgin and extra virgin olive oil, has ver...  
WO/2018/157801A1
The present invention relates to a cyano group-substituted fused bicyclic derivative, and a pharmaceutical composition comprising the compound. The compound or the pharmaceutical composition can be used for inhibiting xanthine oxidase an...  
WO/2018/154519A1
The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compo...  
WO/2018/150230A1
The present disclosure generally relates to the method of preparation of compounds of Formula IV. An aspect of the present disclosure relates to a process for preparation of compound of Formula IV, said process comprising the step of rea...  
WO/2018/151551A1
Disclosed are a catalyst for preparing an alkylene carbonate, a method for preparing the same, and a method and an apparatus for preparing an alkylene carbonate by reacting an alkylene oxide and carbon dioxide by using the catalyst, wher...  
WO/2018/144717A1
The present invention is directed to novel pleuroniutilin antibiotic compounds, intermediates which are useful for making these novel amibioiic compounds aad related methods and pharmaceutical compositions for treating pathogens, especia...  
WO/2018/130625A1
The present invention relates to novel substituted benzene disulfonamides, as well as pharmaceutical compositions containing at least one of these substituted benzene disulfonamides together with at least one pharmaceutically acceptable ...  
WO/2018/129552A1
The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-sta...  
WO/2018/124148A1
The purpose of the present invention relates to providing a novel glyceric acid ester which can be produced at a high yield and for which use as a synthesis intermediate can be expected, and a method for producing same. The purpose of th...  
WO/2018/125878A1
A method of treating an organic carbonate stream comprising passing the organic carbonate stream through a fixed bed to remove contaminants and produce a less contaminated stream wherein the fixed bed comprises alumina or silica.  
WO/2018/124149A1
The purpose of the present invention is to provide a method for producing glyceric acid ester that enables easy, high-yield production and makes it easy to reuse pyridines that are used for a reaction. Provided is a method for producing ...  
WO/2018/116207A1
The present invention relates to a process for preparing cyclic acetals that can be used as components for diesel fuel. More specifically, the present invention relates to a process for preparing cyclic acetals having an ethereal functio...  
WO/2018/113628A1
The present invention relates to a rapid continuous-flow synthesis process for fluoroethylene carbonate and an integrated continuous-flow reactor to implement the process. In the continuous-flow synthesis process, raw materials to be flu...  
WO/2018/118827A1
The present invention is directed to compounds of Formula I, pharmaceutical compositions comprising the same, and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the tr...  
WO/2018/114733A1
The present invention relates to a process for the stereoselective preparation of a compound of the general formula S,S-Ior R,R-I, having an enantiomeric and diastereomeric purity of at least 90%,wherein R1 is C1-C4-alkyl, C2-C4-alkenyl,...  
WO/2018/101207A1
The present invention addresses the problem of providing: a polymerizable liquid crystal composition that makes it possible to manufacture an optical film that has excellent light resistance; and an optically anisotropic membrane, an opt...  
WO/2018/095814A1
The invention is directed to the field of pro-fragrances used in detergents and cleaning agents, cosmetic agents and air fresheners, for example. The invention relates to particular cyclic ketals used as pro-fragrances. The invention als...  
WO/2018/095488A1
The invention relates to sulfobetaine compounds, a process for synthesizing same, and the uses of sulfobetaine compounds for synthesizing antimicrobial materials, antistatic materials, antifouling materials, printing inks, surface-active...  
WO/2018/092087A1
Methods for stabilizing one or more peroxide compounds in solution comprising adding to the solution an effective amount of at least one compound selected from the group comprising (i) cyclic carbonates; (ii) poly-phosphonic acid chelati...  
WO/2018/083357A1
The invention relates to organocatalysts for producing cyclic carbonates. More specifically, the invention relates to imidazole-derived organocatalysts and to the use thereof for the production of cyclic carbonates from epoxides and carb...  
WO/2018/079693A1
Provided are: a pharmaceutical for preventing and/or treating symptoms of depression, the pharmaceutical comprising (S)-norketamine or a pharmacologically acceptable salt thereof; a pharmaceutical composition for preventing and/or treati...  
WO/2018/079333A1
The present invention provides a spontaneous alignment assistant for liquid crystal compositions, which is capable of ensuring storage stability if added to a liquid crystal composition, while enabling vertical alignment of liquid crysta...  
WO/2018/079693A9
Provided are: a pharmaceutical for preventing and/or treating symptoms of depression, the pharmaceutical comprising (S)-norketamine or a pharmacologically acceptable salt thereof; a pharmaceutical composition for preventing and/or treati...  
WO/2018/079988A1
The present invention relates to a compound simultaneously inhibiting a heat shock protein Hsp90 and a Hsp90 homologous protein such as TRAP1 and, more specifically, to: a compound having a structure of the following chemical formula I, ...  
WO/2018/075275A1
Disclosed are of the protected photoinitiators of the formula: wherein Aryl1 is an aromatic or heteroaromatic ring; Aryl2 is an aromatic ring; each R1 is an alkyl, an aryl, an electron donating group or an electron withdrawing group, and...  
WO/2018/074926A1
The present invention relates to new bi-functional and polyfunctional bis- dioxolanes and bis-dioxanes. The present inventors have established that the bis- dioxolanes and bis-dioxanes of the invention are highly advantageous as building...  
WO/2018/074675A1
The present invention relates to a method for preparing a five-membered cyclic carbonate compound, characterized in that carbon dioxide and an epoxy compound are reacted under relatively mild reaction conditions by using, as a catalyst, ...  
WO/2018/074382A1
Provided are an onium salt and a composition which are appropriately usable in a resist composition for a lithography process, wherein two kinds of active energy rays including first active energy rays such as electron beams or extreme u...  
WO/2018/065715A1
The invention relates to a hydrocarbon polymer of formula (I): wherein F1 and F2 are the exo-vinylene cyclic carbonate monovalent radicals, of formulas (IIa) and (IIb), respectively: wherein: g and d are equal to 0, 1, 2 or 3; A is a C1-...  
WO/2018/055065A1
The present invention describes the use and production of a solketal ether compound of formula (I), in particular solketal-ter-amyl-ether (STAE), in diesel fuels, gasoline, and rapeseed biodiesel, with 5 which the limited solubility of t...  
WO/2018/054713A1
The invention relates to compounds having two or more exovinylene cyclic-carbonate units, said exovinylene cyclic-carbonate units being bound together by means of at least one organic siloxane-free compound group which is not directly co...  

Matches 1 - 50 out of 12,100