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Matches 551 - 600 out of 6,959

Document Document Title
WO/2005/000832A1
By using a charge-transporting thin film which is made of a charge-transporting varnish containing, as an electron-acceptor material, a 1,4-benzodioxane sulfonic acid compound represented by the formula (1) below especially in an OLED de...  
WO/2004/113314A1
The present invention relates to optically active dihydroxy hexanoate derivatives, boronate esters of formula (IIa) which are useful intermediates for the synthesis of HMG-CoA enzyme inhibitors like atorvastatin, cerivastatin, rosuvastat...  
WO/2004/110418A2
Disclosed herein are carbonyl compounds of Formula (I), (II) or (III), and others as described herein. Also disclosed are methods of treating disease, such as cancer, neurological disorders, including polyglutamine-repeat disorders, anem...  
WO/2004/108697A1
The invention relates to protected 5,7-dihydroxy-4,4-dimethyl-3-oxoheptanoic acid esters and 5,7-dihydroxy-2-alkyl-4,4-dimethyl-3-oxoheptanoic acid esters for synthesizing epothilones and derivatives thereof, and to methods for producing...  
WO/2004/108733A1
Prodrugs of 6-β-hydroxymethylpenicillanic acid sulfone having the structure wherein R is H or methyl, each X is methylene, and Y is 0, or wherein R is H, each X is 0 and Y is methylene, and solvates thereof are disclosed. Also disclosed...  
WO2004078144A3
The present invention relates to Diphenylethylene Compounds and compositions comprising a Diphenylethylene Compound. The present invention also relates to methods for preventing or treating various diseases and disorders by administering...  
WO2004092106A3
Process for preparing alkoxy- and aryloxy-phenols, comprising oxidizing the ketone of formula (I) with peracids to give the corresponding ester of formula (II) which is then hydrolysed to give the corresponding aryloxy- or alkoxy-phenol.  
WO/2004/103560A1
The present invention concerns a catalytic composition comprising a catalyst effective for catalysing asymmetric hydrogenation reactions, which catalyst requires acid activation, an acidic material effective for activating the catalyst, ...  
WO/2004/101483A1
A novel compound for overcoming diseases including diabetes, obesity and neuroses such as nerve damage, Alzheimer and Parkinson's disease; and a medical agent comprising the same. In particular, there are provided a compound of the follo...  
WO/2004/099173A1
Novel glycerol cyclic pyruvate derivates were prepared and demonstrated to inhibit the binding of an immobilized D-proline derivative to serum amyloid P component (SAP) have been prepared. As such, the compounds of the invention are usef...  
WO2004052919A3
Novel PDF inhibitors and novel methods for their use are provided.  
WO2004080377A3
This invention relates to compounds of the general formula (I) useful as modulators of the KCNQ channel, to pharmaceutical compositions comprising these compounds, and to methods of treatment herewith.  
WO2004080379A3
The invention relates to extracts of Pangium edule, advantageously from seeds, and lignanes of formula I. The invention also relates to the use thereof as a medicament which inhibits cathepsins or which has an antinecrotic effect.  
WO/2004/092106A2
Process for preparing alkoxy- and aryloxy-phenols, comprising oxidizing the ketone of formula (I) with peracids to give the corresponding ester of formula (II) which is then hydrolysed to give the corresponding aryloxy- or alkoxy-phenol.  
WO/2004/089927A1
Methods of inhibiting the cytokine or biological activity of Macrophage Migration Inhibitory Factor (MIF) comprising contacting MIF with a compound of formula (I) are provided. The invention also relates to methods of treating diseases o...  
WO2004046105A3
Atorvastatin and related 3,5-dihydroxy-7-pyrrol-1-yl heptanoic acids can be made by oxidation of a 3,5-dihydroxy-7-pyrrol-1-yl heptanol precursor from novel but readily accessible starting materials. Silylether-protected 7-amino-3,5-dihy...  
WO/2004/083153A1
A process for production of an allyl and/or methallyl ether of a tri or polyhydric alcohol is disclosed. Said process comprises (i) subjecting at least one cyclic formal of a tri or polyhydric alcohol to allylation, (ii) subjecting obtai...  
WO2004050613A3
This invention provides 2-substituted-propenamide derivatives and their compositions for the treament of hepatitis B virus and/or hepatitis D virus.  
WO/2004/080947A1
A compound represented by the following general formula (I), its salt, its solvate or its N-oxide or prodrugs thereof: (I) wherein R1 and R2 represent each an optionally substituted cyclic group, etc.; W is a spacer having from 1 to 6 ca...  
WO/2004/080377A2
This invention relates to compounds of the general formula (I) useful as modulators of the KCNQ channel, to pharmaceutical compositions comprising these compounds, and to methods of treatment herewith.  
WO/2004/080379A2
The invention relates to extracts of Pangium edule, advantageously from seeds, and lignanes of formula I. The invention also relates to the use thereof as a medicament which inhibits cathepsins or which has an antinecrotic effect.  
WO/2004/078144A2
The present invention relates to Diphenylethylene Compounds and compositions comprising a Diphenylethylene Compound. The present invention also relates to methods for preventing or treating various diseases and disorders by administering...  
WO/2004/077511A2
The present invention provides novel (meth)acrylic and (meth)acrylamide monomers and polymers produced from those monomers. The monomers of the invention each include only a single vinyl functionality and at least one non-vinyl functiona...  
WO2004022523A3
The present invention relates to compounds of formula (AA), (I) and (X), useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment ...  
WO/2004/076401A1
The invention relates to arlylcycloalkyl-substituted alkanoic acid derivatives and the physiologically acceptable salts and physiologically functional derivatives thereof. Disclosed are compounds of formula (I), wherein the radicals have...  
WO/2004/073606A2
The present invention is directed to a compound of Formula (I):, and pharmaceutically acceptable salts, solvates, hydrates or stereoisomers thereof, which are useful in treating or preventing disorders mediated by a peroxisome proliferat...  
WO2003102536A3
Destructible surfactants and methods of using same are provided. The invention includes anionic surfactants having a dioxolane or dioxane functional group that enable degradation of the surfactant under acidic conditions. The invention a...  
WO/2004/072254A2
The present invention relates to non-steroidal ligands for use in nuclear receptor-based inducible gene expression system, and a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding...  
WO/2004/072087A2
The invention relates to novel metal complexes for optical data carriers, whereby the latter is preferably a transparent substrate which is, optionally already covered with one or several reflective layers. A light-inscriptible informati...  
WO2004037807A9
The present invention relates to novel compounds of formula (I), and salts, solvates and physiologically acceptable derivatives thereof, to a process for their manufacture, to pharmaceutical compositions containing them, and to their use...  
WO2004048320B1
Biguanide and dihydrotriazine derivatives, preferably substituted asymmetrical imidodicarbonimidic diamides derived from hydroxylamines, and compositions containing biguanide and dihydrotriazine derivatives are disclosed. In addition, me...  
WO2003049702A8
Compounds having the general structure of the Formula (I) and compositions containing them, for treatment of various diseases.  
WO/2004/064745A2
Processes for preparing racemic and optically pure 3,6-dihydro-2H-pyrans of formulae H, I, N and O are described. These compounds may be further transformed into compounds of formulae J, K, L, M, P, Q, S, T, U, V, Y and Z with potential ...  
WO2003086288A3
Novel compounds of the structural formula (I) are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds...  
WO/2004/063147A1
The invention provides salts and solvated of glucagon antagonists.  
WO/2004/063187A1
Disclosed are benzoyl derivatives of formula (I) and the use thereof as herbicides. In said general formula (I), R1, R2, and R3 represent different radicals, X represents a bridge atom from the group comprising oxygen and sulfur, and Het...  
WO/2004/062590A2
The use of bicyclic carbohydrates for the treatment of parasite infections is described. Different bicyclic carbohydrates have been tested in vitro against a number of protozoa. These compounds also have been screened against viruses, tu...  
WO2004037773A8
The present invention relates to novel compounds of formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of...  
WO2004013121A3
The present invention relates to preparing lactic acid derivatives that are useful as odorants and monomers for polymer synthesis.  
WO/2004/054997A1
Compounds represented by the general formula (I) can be produced by reacting a benzene compound represented by the general formula (IV) or (V) with an alkenylidene diacetate represented by the general formula (VI) in the presence of a ca...  
WO/2004/052876A1
Urea-containing, substituted 4-phenyl-[1,3]-dioxanes, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, obesity or a sleep/wake disorder mediated by orexin-2 are described.  
WO/2004/052830A1
ABSTRACT The compounds of formula (I): where Ar is an aromatic ring and Ra, Rb, are as defined in the description, are useful in therapy as drugs for the treatment of diseases mediated by infiltrations of neutrophils induced by IL-8, suc...  
WO/2004/052839A1
The invention relates to isophtalic acid derivatives, a method for the preparation thereof and the use of said derivatives for producing drugs for treating and/or preventing diseases, in particular cardiovascular diseases of a human bein...  
WO/2004/052919A2
Novel PDF inhibitors and novel methods for their use are provided.  
WO2004037807A3
The present invention relates to novel compounds of formula (I),and salts, solvates and physiologically acceptable derivatives thereof, to a process for their manufacture, to pharmaceutical compositions containing them, and to their use ...  
WO2004018414A3
The present invention relates to compounds of formula I or a pharmaceutically acceptable salt thereof, wherein X=NH Y=CO, CS, -C(=N-CN) or X and Y together form an alkene, or C3-C5 cycloalkyl; R1 is -COOH; R2 is an electron withdrawing g...  
WO/2004/050613A2
This invention provides 2-substituted-propenamide derivatives and their compositions for the treament of hepatitis B virus and/or hepatitis D virus.  
WO/2004/048329A1
The present invention provides antitumor compounds of the formula (I); and antitumor methods.  
WO/2004/048320A1
Biguanide and dihydrotriazine derivatives, preferably substituted asymmetrical imidodicarbonimidic diamides derived from hydroxylamines, and compositions containing biguanide and dihydrotriazine derivatives are disclosed. In addition, me...  
WO/2004/046074A1
Di(ketene acetals) are prepared by photoisomerizing the corresponding di(vinyl acetals).  

Matches 551 - 600 out of 6,959