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Matches 51 - 100 out of 7,706

Document Document Title
WO/2017/088738A1
The present invention discloses a modified compound of andrographolide, and particularly discloses a compound shown in formula (I) and (II) or a pharmaceutically acceptable salt thereof.  
WO/2017/078927A1
Novel compounds having a formula (I), embodiments of a method of making the same, and of a composition comprising them are disclosed herein. Also disclosed are embodiments of a method of treating or preventing a metabolic disorder in a s...  
WO/2017/077552A1
A process for the preparation of intermediates 9, useful in the synthesis of sofosbuvir, as well as intermediates of formula [12] are disclosed herein.  
WO/2017/068496A1
The present application relates to an improved process for the preparation of Eliglustat or its pharmaceutically acceptable salts thereof. Further relates to isolation of intermediates in the form of solid and their use for preparation o...  
WO/2017/050298A1
The present invention relates to compounds effective in treating hepatotoxicity and fatty liver diseases and uses thereof.  
WO/2017/053793A1
Methods and systems for making intermediates in the synthesis of onapristone are provided. Aspects include the photoconversion of onapristone synthesis intermediates using a narrow band frequency light source.  
WO/2017/014013A1
A compound represented by formula (1). For example, R1 represents an alkyl group having 1-15 carbon atoms; MES represents a mesogenic group having at least one ring; Sp1 represents a single bond or an alkylene group having 1-10 carbon at...  
WO/2017/010399A1
Provided are compounds having RORγt inhibitory effects represented by formula (I). Compounds represented by formula (I) (wherein L represents -NR1ACO-, -SO2- or the like, A represents a substituted or unsubstituted aromatic carbocyclic ...  
WO/2016/207711A8
The present invention provides a method for producing modified lignin, novel modified lignin and novel epoxy resin, as well as novel bisphenol compounds, and resin compositions including these novel bisphenol compounds and novel epoxy re...  
WO/2016/208483A1
The present invention provides a compound represented by general formula (I) and also provides a composition containing the compound, a polymer obtained by polymerizing the composition, and a liquid crystal display element. The compound ...  
WO/2016/207711A1
The present invention provides a method for producing modified lignin, novel modified lignin and novel epoxy resin, as well as novel bisphenol compounds, and resin compositions including these novel bisphenol compounds and novel epoxy re...  
WO/2016/198374A1
Substituted aromatic sulfonamides of formula (I) pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a di...  
WO/2016/201214A1
The present invention relates to compounds which have been discovered to be potent ligands (inhibitors) of human GLUT5 (glucose transporter type 5), a facilitative glucose transporter that transports fructose, and their use as ligands as...  
WO/2016/192631A1
The present invention provides an abietane-type diterpene compound having lipid-lowering activity, a method for preparing same, and use of same. Specifically, the compound has the structure shown in formula I. The definitions of the grou...  
WO/2016/183053A1
Embodiments of the present disclosure pertain to methods of monitoring an environment for the presence of a solvent by: (i) exposing the environment to a luminescent compound, where the relative luminescence emission intensity of the lum...  
WO/2016/174161A1
The invention relates to a method and a device for manufacturing lactide, whereby crude lactide, being prepared by means of depolymerization of lactic acid oligomers, is purified by means of a distillation step. According to the inventio...  
WO/2016/172275A1
The present disclosure provides compositions and methods that are useful in removing, lowering the amount of, or otherwise controlling hydrogen sulfide and mercaptans. The compositions and methods can be used in any industry where hydrog...  
WO/2016/160579A1
This invention provides efficient and scalable enantioselective methods that yield 2-alkyl-2-allylcycloalkyanone compounds with quaternary stereogenic centers. Methods include the method for the preparation of a compound of formula (I), ...  
WO/2016/151009A1
The invention relates to compounds having general formula (I): where R = H, CH2-OH, CH2-O-CO-CH3, CH2-O-CO-Ph (Ph=phenyl) R' = H, CH2-O-CO-CH3, CH2-O-CO-Ph (Ph = phenyl) Ar = phenyl, 3-methoxy-4-hydroxy phenyl, 2-furyl. These are compoun...  
WO/2016/133035A1
Provided are: a liquid crystalline compound which satisfies at least one of such physical properties as high stability with respect to light or the like, high clearing point, low lower limit temperature of a liquid crystal phase, low vis...  
WO/2016/129490A1
Provided is a polar compound having high chemical stability, high ability to align liquid crystal molecules, and high solubility in a liquid crystal composition, and which has a large voltage holding ratio when used in a liquid crystal d...  
WO/2016/127940A1
Disclosed are a cyclic carbonate monomer containing double iodine, a biodegradable polymer prepared thereby and a use. The polymer can be obtained by ring-opening polymerization of the cyclic carbonate monomer containing double iodine, w...  
WO/2016/128501A1
The invention pertains to a method for producing lactide comprising the steps of - providing a solution of lactic acid in a volatile organic solvent, - subjecting the solution to an evaporation step to remove volatile organic solvent and...  
WO/2016/122325A1
The invention relates to the field of medicinal chemistry, In particular, it relates to methods for providing intermediates in the synthesis of Atorvastatin, a competitive inhibitor of HMG-Co A reductase. Provided is a process for provid...  
WO/2016/123426A2
Various esterified alkyl ketal ester or hydroxyalkyl ketal ester products are useful as components of organic polymer compositions. The ketal esters are produced in certain transesterifications between alkyl ketal esters and/or hydroxyal...  
WO/2016/123426A3
Various esterified alkyl ketal ester or hydroxyalkyl ketal ester products are useful as components of organic polymer compositions. The ketal esters are produced in certain transesterifications between alkyl ketal esters and/or hydroxyal...  
WO/2016/116420A1
The present invention relates to a delivery system based on photosensitive acetal or ketal compounds capable of liberating upon exposure to light an active volatile carbonyl compound in a controlled manner from a surface into the surroun...  
WO/2016/105030A1
The present invention relates to an organic electroluminescent device comprising a novel compound having excellent light emitting capability and at least one organic layer containing the compound, thereby improving characteristics such a...  
WO/2016/105448A1
This disclosure provides compounds and compositions for use as analgesics and for the treatment of various conditions, such as pain, headaches, allodynia, and fibromyalgia. The disclosure also provides compounds that are ligands, and in ...  
WO/2016/097750A1
A process for the production of lactic acid comprising: (a) reacting a stream rich in saccharide with sodium hydroxide in the presence of water to produce a reaction mixture comprising sodium lactate; and (b) subjecting at least part of ...  
WO/2016/097840A1
The invention relates to a novel product and more specifically a glycerol acetal or glycerol ketal ether-ester, to the methods for the production thereof, and to the use of same as a solvent, co-solvent, plasticiser, coalescing agent, su...  
WO/2016/097569A1
The invention relates to novel fragrant compounds having animalic or ambergris notes, without any woody characteristic. More specifically, the invention relates to novel acetal derivatives of 1-(3,3-dimethylcyclohex-1-enyl) ethanone of g...  
WO/2016/092546A1
Methods and compositions utilizing 2-aminoindan derivatives collectively represented by Formula I as described and defined in the specification for regulating binge behavior, particularly binge drinking, are disclosed.  
WO/2016/091024A1
Disclosed are an acetal-substituted glucamide and a preparation method thereof, and a method for preparing a supramolecular gel, wherein the acetal-substituted glucamide is as shown in formula I, wherein n is one of 1-10, 12, 14, 16 or 1...  
WO/2016/092547A1
Alcoholic beverage-substitutes such as a beer-substitute, a wine-substitute, a cider-substitute, an alcopop-substitute or a spirit-substitute beverage, comprising a base liquid (e.g., a base beverage) and a 2-aminoindan derivative such a...  
WO/2016/078505A1
Provided is a preparation method of a fluorene ethyl ketone derivative, particularly a preparation method of a compound of formula I, each group being as defined in the specification. The compound can be used as an intermediate in the pr...  
WO/2016/074324A1
Provided is a preparation method of 2-((4R, 6S)-6-bromomethyl-2, 2-dimethyl-1, 3-dioxane-4-yl)acetate (I). Such compound is a key chiral intermediate in preparing a statins lipid-lowering drugs. The method comprises: carrying out a bromi...  
WO/2016/070708A1
Disclosed is a fluorinated liquid crystal containing a difluoromethoxy (CF2O) bridge bond and a composition thereof as well as the preparation method and use thereof. In the method of the present invention, difluoro dibromomethane is use...  
WO/2016/056031A1
The patent discloses novel diol derivatives of general formula I, [Formula should be inserted here] A chiral pool process for the synthesis of the compound of formula I from D glucose. Further, it discloses a process for the synthesis of...  
WO/2016/046843A1
Novel methods for preparation of Carfilzomib and intermediates thereof with high stereo selection are reported. The synthetic procedures result in substantially pure Carfilzomib (I).  
WO/2016/028959A1
Disclosed are compounds of Formulas (I), (II), (III), (IV), and (V) and/or a salt thereof, wherein R1 is OH or OP(O)(OH)2, and X1, X2, X3, R2, R2a, Ra, Rb, and Rc are defined herein. Also disclosed are methods of using such compounds as ...  
WO/2016/008411A1
Disclosed are compounds of Formula (I), pharmaceutical compositions comprising the same, processes for the preparation thereof, and the use thereof.  
WO/2016/001885A3
The present application relates to the solid state forms of Eliglustat hemitartrate and the processes for the preparation thereof. The application further provides solid dispersion of Eliglustat hemitartrate having Eliglustat hemitartrat...  
WO/2015/195656A3
Methods of making compounds of Formula (I) are disclosed.  
WO/2015/184256A2
The present invention provides, in part, a biodegradable compound of formula I, and sub- formulas thereof:Formula (I) or a pharmaceutically acceptable salt thereof, where each X independently is O or S, each Y independently is O or S, an...  
WO/2015/175984A1
Described herein are compounds which can be used in topical liquids, creams, or other dosage forms such as solids, for reducing intraocular pressure, treating glaucoma, growing hair, treating wounds, or other medical and/or cosmetic uses.  
WO/2015/168998A1
The present invention relates to a preparation method for a chiral intermediate for use in statins, acquired with chloroacetic acid and benzyl alcohol as starting materials via a series of reactions, namely etherification, condensation, ...  
WO/2015/160641A2
The present disclosure generally relates to compounds useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical composit...  
WO/2015/155230A1
The present invention provides novel cell-permeable succinates and cell permeable precursors of succinate aimed at increasing ATP-production in mitochondria. The main part of ATP produced and utilized in the eukaryotic cell originates fr...  
WO/2015/156580A2
The present invention relates to a novel organic compound and an organic electroluminescent element comprising same. The organic compound according to the present invention is used for the organic layer(s) of an organic electroluminescen...  

Matches 51 - 100 out of 7,706