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WO/2012/023584 |
Provided are a composition derived from ascorbic acid, a method for preparing the composition, and a cosmetic material having the composition mixed therein. The composition derived from ascorbic acid comprises a reaction product obtained...
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WO/2012/017242 |
A process is provided for preparing a compound of the following general formula (I) wherein R1 represents hydrogen, an alkyl group of 1 to 12 carbon atoms, an aryl group of 6 to 12 carbon atoms or an aralkyl group of 7 to 12 carbon atoms...
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WO/2012/017166 |
or an addition salt thereof with pharmaceutically acceptable acids, for use thereof in a method for treatment of a pathological condition linked to an excessive effect of TNF-alpha and for use thereof in a method for treatment of the hum...
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WO/2012/017166 |
or an addition salt thereof with pharmaceutically acceptable acids, for use thereof in a method for treatment of a pathological condition linked to an excessive effect of TNF-alpha and for use thereof in a method for treatment of the hum...
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WO/2012/010172 |
The present invention relates to methods of producing ingenol-3-angelate (I) from ingenol (II). Formula (I) and (II). Furthermore, the invention relates to intermediates useful for the synthesis of ingenol-3-angelate (I) from ingenol (II...
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WO/2012/007379 |
Process for the manufacture of a cyclic diester of an alpha-hydroxyacid comprising heating the alpha-hydroxyacid at a temperature from 100 to 250°C in the presence of at least one polyol and of at least one catalyst selected from the gr...
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WO/2012/001601 |
The invention relates to compounds, in particular phosphinic ligands of metal complexes, as well as to metal complexes including said ligands and to supported catalysts including said metal complexes or said compounds. The invention also...
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WO/2012/000921 |
Process for the manufacture of lactide comprising heating lactic acid in the presence of at least one hygroscopic salt present in an amount of at least 1 mol per mol of lactic acid.
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WO/2011/163671 |
Compounds derived from acetone are provided. Particularly, the compounds are derivatives of hydroxyacetone, including dimers of both 1-hydroxyacetone and 1,3-dihydroxyacetone. The hydroxy moieties on the core hydroxyacetone molecule serv...
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WO/2011/163671 |
Compounds derived from acetone are provided. Particularly, the compounds are derivatives of hydroxyacetone, including dimers of both 1-hydroxyacetone and 1,3-dihydroxyacetone. The hydroxy moieties on the core hydroxyacetone molecule serv...
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WO/2011/159297 |
GPR120 agonists are provided. These compounds are useful for the treatment of metabolic diseases, including Type II diabetes and diseases associated with poor glycemic control.
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WO/2011/159219 |
Disclosed is a process for production of a cycloaliphatic carbonate from a diol, triol or polyol and a carbon dioxide source, such as a dialkyl carbonate. Said process is performed in a solvent-free medium using a N-heterocyclic carbene ...
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WO/2011/150513 |
Anti-virally active carbanucleosides such as entecavir are prepared by a process which utilizes, throughout the synthesis, an aromatic protectant group for the hydroxyl and the alkyl hydoxy groups of the starting material, removed as the...
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WO/2011/138665 |
The present invention provides dihydroorotate dehydrogenase inhibitors of formula (I), methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of diseases or disorde...
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WO/2011/135046 |
A one pot method of preparing cyclic carbonyl compounds comprising an active pendant pentafluorophenyl carbonate group is disclosed. The cyclic carbonyl compounds can be polymerized by ring opening methods to form ROP polymers comprising...
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WO/2011/132712 |
Provided is a novel compound that is useful as a medical drug in that said compound displays strong antimicrobial activity against gram-negative bacteria such as Pseudomonas aeruginosa and drug-resistant strains thereof, on the basis of ...
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WO/2011/122666 |
Disclosed is a method for simply and efficiently producing a benzodioxane compound. The target benzodioxane compound is obtained by reacting a phenol compound with a carbonate compound in the presence of a base. This method can produce t...
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WO/2011/114220 |
Isolated compounds from adelostemma gracillimum refined fractions and compositions containing the compounds are provided by the present invention. Adelostemma gracillimum refined fractions and the extraction process thereof are also prov...
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WO/2011/104728 |
A process for the synthesis of 100% optically pure L(+) lactide catalyzed by zinc and tin metal catalysts of less than 150 micron particle size is disclosed. The L- Lactide obtained was further purified to obtain lactide of 100% optical ...
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WO/2011/105649 |
The present invention is useful as a HMG-Co A reductase inhibitor and relates to a new method for manufacturing pitavastatin hemicalcium which is used as a treatment for hyperlipidemia. More specifically, a new method for manufacturing p...
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WO/2011/103442 |
This invention relates to compounds having the structure: wherein bonds α, β, γ, δ, ω, η, χ, ε, κ, and μ are each present or absent, and R1-R18 are various substituents described herein.
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WO/2011/100608 |
The patent application relates to a method of producing a monomer component from a genetically modified polyhydroxyalkanoate (PHA) biomass, wherein the biomass is heated in the presence of a catalyst to release a monomer component from t...
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WO/2011/092564 |
Intermediates, process for their preparation and their use in the preparation of therapeutically effective antineoplastic agents, in particular Temsirolimus of formula (I).
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WO/2011/092564 |
Intermediates, process for their preparation and their use in the preparation of therapeutically effective antineoplastic agents, in particular Temsirolimus of formula (I).
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WO/2011/092564 |
Intermediates, process for their preparation and their use in the preparation of therapeutically effective antineoplastic agents, in particular Temsirolimus of formula (I).
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WO/2011/092564 |
Novel intermediates, process for their preparation and their use in the preparation of therapeutically effective antineoplastic agents, in particular Temsirolimus of formula (I).
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WO/2011/089802 |
Disclosed is a method for producing glycolide, which comprises: a step wherein a mixture containing a glycolic acid oligomer, a high boiling point polar organic solvent having a boiling point of 230-450˚C and a tin compound is heated, a...
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WO/2011/086584 |
The present invention relates to an improved process for the preparation of amide intermediates useful in the preparation of cholesterol reducing agents.
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WO/2011/084466 |
Disclosed herein are processes for preparing cyclic esters comprising unsaturated functional groups. Also disclosed are copolymers prepared from the cyclic esters. The copolymers can be used to form microparticles, polymer micelles, etc....
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WO/2011/082460 |
The present invention relates to a method for purifying light-coloured glycerol from biodiesel production, comprising a step during which a liquid phase containing an heterocyclic intermediate product, a ketal, is obtained, allowing orga...
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WO/2011/073100 |
The invention relates to novel acylmethylene-1,3-dioxolanes and acylmethylene-1,4-dioxanes of the general formula (I), in which R1, R2, R3 and n are defined as in the description, and to a novel method for the production thereof. Acylmet...
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WO/2011/071136 |
A therapeutic agent for fibromyalgia, comprising a 5-HT2C receptor agonist as an active ingredient.
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WO/2011/061277 |
Amino phenyl acetamide compounds of Formula (I):and pharmaceutically acceptable salts thereof: wherein R1, R2, R3 and Ra are as defined in the description, use of such compounds in the chemotherapy of certain parasitic protozoal infectio...
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WO/2011/059731 |
The present invention is directed to novel alkynyl derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by DPP-1.
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WO/2011/051960 |
The invention relates to processes for the preparation of compound of CCI-779 having the Formula (I), which is useful as an antineoplastic agent. The invention further relates to certain novel intermediates useful in the preparation of c...
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WO/2011/051960 |
The invention relates to processes for the preparation of compound of CCI-779 having the Formula (I), which is useful as an antineoplastic agent. The invention further relates to certain novel intermediates useful in the preparation of c...
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WO/2011/048425 |
The invention concerns a continuous process for the production of compounds having the general formula (6) comprising providing to a reaction zone a continuous stream of an alkyl acetate and a continuous stream of an alkali metal or alka...
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WO/2011/038857 |
Suggested are alkoxylated glycerol acetals according to formulae (Ia) and (Ib) in which R1 stands for a linear or branched, saturated or unsaturated and optionally substituted hydrocarbyl residue comprising 6 to 22 carbon atoms and O or ...
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WO/2011/038857 |
Suggested are alkoxylated glycerol acetals according to formulae (Ia) and (Ib) in which R1 stands for a linear or branched, saturated or unsaturated and optionally substituted hydrocarbyl residue comprising 6 to 22 carbon atoms and O or ...
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WO/2011/038857 |
Suggested are alkoxylated glycerol acetals according to formulae (Ia) and (Ib) in which R1 stands for a linear or branched, saturated or unsaturated and optionally substituted hydrocarbyl residue comprising 6 to 22 carbon atoms and O or ...
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WO/2011/038337 |
Ketal lactones of and methods for making such ketal lactones are disclosed. Also described are methods for making isolated cis- and trans- stereoisomers of hydroxyester ketals of oxocarboxylic acids and polymers having ketal units of suc...
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WO/2011/033937 |
Disclosed are: a liquid crystalline compound having stability to heat, light and the like, capable of forming a nematic phase in a broad temperature range, and having a low viscosity, high optical anisotropy, a proper elastic constant (K...
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WO/2011/034078 |
Disclosed is a compound which is useful as the active ingredient of a medicinal composition, in particular, a medicinal composition for preventing and/or treating a VAP-1 associated disease. As the results of intensive studies on compoun...
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WO/2011/027888 |
Disclosed are a diamide-phenyl derivative which inhibits soluble epoxy hydrolase (sEH), and a pharmaceutically acceptable salt of the diamide-phenyl derivative. Specifically disclosed are a compound represented by formula (I), and a phar...
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WO/2011/020536 |
The invention relates to the use of glyceraldehyde derivatives and the acetals thereof for releasing active molecules, which are skin-tanning substances, UV filters, preservatives, or coolants. The invention also relates to novel glycera...
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WO/2011/013077 |
The invention is directed to the use of compounds of formula (I), as fragrant agents. In this formula: - R3 and R4 are independently a hydrogen atom, a C1-C6 alkyl group or a C2-C6 alkenyl group, R5 is a C1-C6 alkyl group, a C2-C6 alkeny...
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WO/2011/009478 |
The invention relates to a method for making a polymer wherein during the polymerisation is incorporated in the polymer chain by ring opening polymerisation a cyclic (alkyl)acryloyl carbonate having the formula (4): wherein R1 and R2 eac...
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WO/2011/009826 |
Chalcone derivatives of the general formula (I), wherein two from among A, B and Z which are adjacent to each other are linked and form a moiety selected from -O-(CH2)n-S(O)m-, -S(O)m-(CH2)n-O- and -O-(CH2)n-O-, and the remaining one fro...
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WO/2011/009826 |
Chalcone derivatives of the general formula (I), wherein two from among A, B and Z which are adjacent to each other are linked and form a moiety selected from -O-(CH2)n-S(O)m-, -S(O)m-(CH2)n-O- and -O-(CH2)n-O-, and the remaining one fro...
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WO/2011/006566 |
The invention relates to specific monomethoxy-hydroxy-benzylmalonates having an amphiphilic-antioxidative activity profile, to methods for producing the same, to preparations and to the use thereof.
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