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Matches 201 - 250 out of 3,567

Document Document Title
WO/2010/003624
Heterocyclic derivatives, processes for their preparation, medicaments comprising these compounds, and the use thereof. The invention relates to compounds of the formula I in which the radicals R1, R2, R3, R4, W, A, B, D, E, G, L, M, R, ...  
WO/2010/000193
The invention provides a process for preparing osemozotan and its pharmaceutically acceptable salts. The invention also provides an intermediate, (2R)-N-[3-(1,3- benzodioxol-5-yloxy)propyl]-1,4-benzodioxin-2-formamide, used in the proces...  
WO/2009/153886
A process for producing an α-hydroxy acid that is economically advantageous without the secondary production of a large volume of waste, having satisfactory quality as a polymer raw material. The process for producing an α-hydroxy acid...  
WO/2009/150248
The present invention relates to a compound of general formula (I) : and also to the pharmaceutically acceptable salts thereof, to the isomers or isomer mixtures thereof in all proportions, in particular to an enantiomer mixture, and esp...  
WO/2009/150963
Disclosed is a liquid crystal compound having general physical properties necessary for a compound, stability against heat, light or the like, a wide temperature range of a liquid crystal phase, a high clearing point, good compatibility ...  
WO/2009/150966
Disclosed is a liquid crystalline compound which is stable against heat, light or the like and has a nematic phase in a wide temperature range, while having a low viscosity, a large optical anisotropy, an adequate elastic constant K33, a...  
WO/2009/147632
The invention provides a method of preparing the stereoisomers of 1,11-diamino-6-aza- undecane-2,4,8,10-tetraol.  
WO/2009/143178
Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Hu...  
WO/2009/133107
The present invention relates to novel 1-(2,3-dihydro-1,4-benzodioxin-2-yl)- methanamine derivatives, useful as modulators of dopamine neurotransmission, and more specifically as dopaminergic stabilizers. In other aspects the invention r...  
WO/2009/133110
The present invention relates to novel1-(4H-1,3-benzodioxin-2-yl)methanamine derivatives, useful as modulators of dopamine neurotransmission, and more specifically asdopaminergic stabilizers. In other aspects the invention relates to the...  
WO/2009/133109
The present invention relates to novel 1-(2,3-dihydro-1,4-benzodioxin-2-yl)-methanamine derivatives, useful as modulators of dopamine neurotransmission, and more specifically as dopaminergic stabilizers. In other aspects the invention re...  
WO/2009/130422
The present invention relates to the use of acylthiourea or acylurea derivatives of formula (I) for the treatment of pathologies involving a tissue dysfunction associated with a deregulation of the Hedgehog protein signalling pathway, an...  
WO/2009/129726
The present invention provides novel nitrones, their preparation and use. The novel compounds have the following formula: I The compounds of the present invention have strong antioxidative activity, and are thrombolytic. These compounds ...  
WO/2009/130422
The present invention relates to the use of acylthiourea or acylurea derivatives of formula (I) for the treatment of pathologies involving a tissue dysfunction associated with a deregulation of the Hedgehog protein signalling pathway, an...  
WO/2009/128521
Disclosed are: a compound having an excellent inhibitory activity on cysteine protease; and a pharmaceutical agent for the treatment or prevention of a disease selected from the group consisting of osteoporosis, osteoarthrosis deformans,...  
WO/2009/117902
Provided herein are 5-demethoxyfumagillol and its derivatives. Also provided herein are methods of making the 5-demethoxyfumagillol and derivatives. Also provided herein are biological activities of the 5-demethoxyfumagillol and derivati...  
WO/2009/120192
The present invention is directed to processes for the preparation of benzo-fused heteroaryl derivatives, useful for the treatment of epilepsy and related disorders. The present invention is further directed to processes for the preparat...  
WO/2009/120192
The present invention is directed to processes for the preparation of benzo-fused heteroaryl derivatives, useful for the treatment of epilepsy and related disorders. The present invention is further directed to processes for the preparat...  
WO/2009/120191
The present invention is directed to a process for the preparation of benzo-fused heteroaryl sulfamates, useful for the treatment of epilepsy and related disorders according to formula (IA) and to a crystalline compound of formula (I-S)....  
WO/2009/117829
Compounds having the general formula (I): wherein X is S, Se or NH, and stereoisomers thereof, and de-O-sulfonated analogues of all of the foregoing, but excluding naturally occurring kotalanol and de-O-sulfonated kotalanol, and methods ...  
WO/2009/111830
The present invention relates to a class of conjugated unsaturated compounds, to a method of preparing such compounds, and to the polymerisation and bio-active uses of such compounds including their use as antimicrobial agents. The inven...  
WO/2009/104722
Provided are 1) polymer compounds having excellent acid reactivity and thermal stability as well as minimal swelling during development, 2) compounds of the following formula that serve as starting materials for said polymer compounds, a...  
WO/2009/089210
The present invention is directed to novel processes for the preparation of sulfamide derivatves, useful in the treatment of epilepsy and related disorders.  
WO/2009/084773
The present invention relates to a preparation process useful in synthesis of atorvastatin, more particularly a process for preparing atorvastatin is effective in treating hyperlipemia, comprising protecting the dihydroxy group at C3 and...  
WO/2009/084773
The present invention relates to a preparation process useful in synthesis of atorvastatin, more particularly a process for preparing atorvastatin is effective in treating hyperlipemia, comprising protecting the dihydroxy group at C3 and...  
WO/2009/080834
Process for the synthesis of a cyclic diester of an alpha-hydroxyacid, comprising the following steps: an alkalino-earth salt of the corresponding alpha-hydroxyacid is mixed with said alpha-hydroxyacid and water; the mixture is treated b...  
WO/2009/077615
The present invention relates to a method for obtaining lactide by thermal cracking of lactic acid oligomers in the presence of a metal salt of the phosphite anion (PO3)3- in which the metal is chosen from the group comprising tin, alumi...  
WO/2009/077385
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing...  
WO/2009/076618
The present invention relates to, in part, novel sulfate and bisphenol compounds useful for the recognition, attachment and growth of unwanted biologies on natural and manmade surfaces. Another aspect of the invention relates to combinat...  
WO/2009/075818
Disclosed herein are methods and intermediates useful in the preparation of macrolides, e.g., compounds of formula (IV) wherein R1-R12 are as defined herein.  
WO/2009/070910
Compounds of formula (I) wherein R1- R5, n and m have the same meaning as given in the description, having cooling properties are disclosed. Furthermore a process of their production and consumer products comprising them are disclosed.  
WO/2009/072502
Disclosed is a method by which various fluorine-containing carbonate compounds can be freely produced with high yield without using phosgene and without by-producing hydrogen chloride. Specifically disclosed is a method wherein a fluorin...  
WO/2009/070910
Compounds of formula (I) wherein R1- R5, n and m have the same meaning as given in the description, having cooling properties are disclosed. Furthermore a process of their production and consumer products comprising them are disclosed.  
WO/2009/072501
Disclosed is a novel method by which various carbonate compounds can be freely produced with high yield without using phosgene and without by-producing hydrogen chloride. Specifically disclosed is a method wherein a compound having a car...  
WO/2009/065035
The invention provides novel therapeutic compounds, pharmaceutical compositions comprising these compounds, and methods for using these compounds and compositions to treat diseases and disorders, such as cancer.  
WO/2009/064031
There is provided a compound having an excellent controlling effect on pests, represented by the formula (I): wherein, A and E independently represent a -R1 group, a -L1-R1 group, etc.; G represents a -L2-R1 group, a -S(O)2-R4 group, etc...  
WO/2009/062224
The invention relates to a method for producing L,L-, D,D-, D,L- or meso-dilactide, comprising polycondensation and/or polytransesterification of L-, D- or D,L-lactic acid or esters thereof to form high-molecular-weight polyesters of L-,...  
WO/2009/060832
Disclosed is a means for producing lactide efficiently in the production of a poly(lactic acid) by depolymerizing a lactic acid oligomer to produce lactide and ring-opening-polymerizing lactide. Also disclosed is a lactide production app...  
WO/2009/060832
Disclosed is a means for producing lactide efficiently in the production of a poly(lactic acid) by depolymerizing a lactic acid oligomer to produce lactide and ring-opening-polymerizing lactide. Also disclosed is a lactide production app...  
WO/2009/053250
The invention relates to compounds of the formula (I), in which the substituents have the meanings given in the description, method for producing said compounds, agents comprising the same, and the use thereof to combat damaging fungi.  
WO/2009/035951
Disclosed are amide, thioamide, urea and thiourea compounds and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and co...  
WO/2009/035951
Disclosed are amide, thioamide, urea and thiourea compounds and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and co...  
WO/2009/030330
The invention relates to a condensation and washing device which can recycle and clean, in particular, process steam that is produced during the production of polylactide. The invention also relates to a polymerisation device for produci...  
WO/2009/031437
Disclosed is a liquid crystalline compound which has stability to heat, light and the like, exhibits a nematic phase in a wide temperature range, has a low viscosity, adequate optical anisotropy and an adequate elastic coefficient K33, a...  
WO/2009/030396
The present invention relates to a method for the production or purification of biodegradable, intramolecular cyclic esters of alpha-hydroxycarboxylic acids, biodegradable alpha-hydroxycarboxylic acids or oligopolymers or polymers thereo...  
WO/2009/024492
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing...  
WO/2009/022311
The invention relates to 1,2-diamido-ethylene derivatives of the formula (I) wherein R1, R 2, R 3, and A are as described in the description and their use as medicaments, especially as orexin receptor antagonists.  
WO/2009/022311
The invention relates to 1,2-diamido-ethylene derivatives of the formula (I) wherein R1, R 2, R 3, and A are as described in the description and their use as medicaments, especially as orexin receptor antagonists.  
WO/2009/019561
The present invention is directed to a 2-deoxyribose-5-phosphate aldolase (DERA) chemoenzymatic process for making chiral compounds.  
WO/2009/019561
The present invention is directed to a 2-deoxyribose-5-phosphate aldolase (DERA) chemoenzymatic process for making chiral compounds.  

Matches 201 - 250 out of 3,567