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Matches 201 - 250 out of 3,589

Document Document Title
WO/2010/022966
The present invention relates to three variants for preparing a mixture of cyclic diesters derived from lactic acid and especially a racemate of dilactide. This can proceed, as desired, from the corresponding a-hydroxycarboxylic acids, t...  
WO/2010/022966
The present invention relates to three variants for preparing a mixture of cyclic diesters derived from lactic acid and especially a racemate of dilactide. This can proceed, as desired, from the corresponding a-hydroxycarboxylic acids, t...  
WO/2010/021093
Provided are a novel asymmetric organic catalyst with which it is possible to realize a high optically-active yield when said catalyst is used in a small amount, and a method for producing a compound using the same. The asymmetric organi...  
WO/2010/020548
The present invention relates to a compound of the general formula (I) wherein R1/R2 are independently from each other lower alkyl, or form together with the N-atom to which they are attached a heterocyclic group, selected from pyrrolidi...  
WO/2010/020370
The invention relates to a method for storing and/or transporting intramolecular cyclic esters (lactones), in particular lactides.  
WO/2010/019911
The present invention includes compositions and methods for inhibiting kinase activity to protect against neurodegeneration including diseases such as Alzheimer's disease, Parkinson's disease, or Huntington's disease, and conditions such...  
WO/2010/018209
The present invention relates to a method of obtaining lactide using a solvent from the family of ethers, starting from a mixture that is in the liquid form comprising lactide, meso-lactide and other impurities.  
WO/2010/019911
The present invention includes compositions and methods for inhibiting kinase activity to protect against neurodegeneration including diseases such as Alzheimer's disease, Parkinson's disease, or Huntington's disease, and conditions such...  
WO/2010/017094
The present invention provides curcumin-derived near infrared (NIR) imaging probes. Upon interacting with amyloid β aggregates, these probes undergo a range of changes, qualifying them as "smart" probes. The inventors have demonstrated ...  
WO/2010/011548
The present invention is directed to novel substituted sulfamide derivatives, pharmaceutical compositions containing said derivatives and the use of said derivatives form in the treatment of anxiety and related disorders; bipolar depress...  
WO/2010/008776
A patch and sensor assembly for use in an EP mapping system has two portions: a reusable portion and a disposable portion. The reusable portion houses the biosensors used in magnetic based location and mapping systems and the electrical ...  
WO/2010/008776
A patch and sensor assembly for use in an EP mapping system has two portions: a reusable portion and a disposable portion. The reusable portion houses the biosensors used in magnetic based location and mapping systems and the electrical ...  
WO/2010/008776
A patch and sensor assembly for use in an EP mapping system has two portions: a reusable portion and a disposable portion. The reusable portion houses the biosensors used in magnetic based location and mapping systems and the electrical ...  
WO/2010/003299
An organic compound and preparation method thereof, particularly a flavor enhancer and preparation method thereof, are disclosed. Its chemical name is 4-isopropyl-5,5-dimethyl-m-dioxan-2-one. It is prepared by the following method: start...  
WO/2010/003624
Heterocyclic derivatives, processes for their preparation, medicaments comprising these compounds, and the use thereof. The invention relates to compounds of the formula I in which the radicals R1, R2, R3, R4, W, A, B, D, E, G, L, M, R, ...  
WO/2010/003624
Heterocyclic derivatives, processes for their preparation, medicaments comprising these compounds, and the use thereof. The invention relates to compounds of the formula I in which the radicals R1, R2, R3, R4, W, A, B, D, E, G, L, M, R, ...  
WO/2010/000193
The invention provides a process for preparing osemozotan and its pharmaceutically acceptable salts. The invention also provides an intermediate, (2R)-N-[3-(1,3- benzodioxol-5-yloxy)propyl]-1,4-benzodioxin-2-formamide, used in the proces...  
WO/2009/153886
A process for producing an α-hydroxy acid that is economically advantageous without the secondary production of a large volume of waste, having satisfactory quality as a polymer raw material. The process for producing an α-hydroxy acid...  
WO/2009/150248
The present invention relates to a compound of general formula (I) : and also to the pharmaceutically acceptable salts thereof, to the isomers or isomer mixtures thereof in all proportions, in particular to an enantiomer mixture, and esp...  
WO/2009/150963
Disclosed is a liquid crystal compound having general physical properties necessary for a compound, stability against heat, light or the like, a wide temperature range of a liquid crystal phase, a high clearing point, good compatibility ...  
WO/2009/150966
Disclosed is a liquid crystalline compound which is stable against heat, light or the like and has a nematic phase in a wide temperature range, while having a low viscosity, a large optical anisotropy, an adequate elastic constant K33, a...  
WO/2009/147632
The invention provides a method of preparing the stereoisomers of 1,11-diamino-6-aza- undecane-2,4,8,10-tetraol.  
WO/2009/143178
Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Hu...  
WO/2009/133107
The present invention relates to novel 1-(2,3-dihydro-1,4-benzodioxin-2-yl)- methanamine derivatives, useful as modulators of dopamine neurotransmission, and more specifically as dopaminergic stabilizers. In other aspects the invention r...  
WO/2009/133110
The present invention relates to novel1-(4H-1,3-benzodioxin-2-yl)methanamine derivatives, useful as modulators of dopamine neurotransmission, and more specifically asdopaminergic stabilizers. In other aspects the invention relates to the...  
WO/2009/133109
The present invention relates to novel 1-(2,3-dihydro-1,4-benzodioxin-2-yl)-methanamine derivatives, useful as modulators of dopamine neurotransmission, and more specifically as dopaminergic stabilizers. In other aspects the invention re...  
WO/2009/130422
The present invention relates to the use of acylthiourea or acylurea derivatives of formula (I) for the treatment of pathologies involving a tissue dysfunction associated with a deregulation of the Hedgehog protein signalling pathway, an...  
WO/2009/129726
The present invention provides novel nitrones, their preparation and use. The novel compounds have the following formula: I The compounds of the present invention have strong antioxidative activity, and are thrombolytic. These compounds ...  
WO/2009/130422
The present invention relates to the use of acylthiourea or acylurea derivatives of formula (I) for the treatment of pathologies involving a tissue dysfunction associated with a deregulation of the Hedgehog protein signalling pathway, an...  
WO/2009/128521
Disclosed are: a compound having an excellent inhibitory activity on cysteine protease; and a pharmaceutical agent for the treatment or prevention of a disease selected from the group consisting of osteoporosis, osteoarthrosis deformans,...  
WO/2009/117902
Provided herein are 5-demethoxyfumagillol and its derivatives. Also provided herein are methods of making the 5-demethoxyfumagillol and derivatives. Also provided herein are biological activities of the 5-demethoxyfumagillol and derivati...  
WO/2009/120192
The present invention is directed to processes for the preparation of benzo-fused heteroaryl derivatives, useful for the treatment of epilepsy and related disorders. The present invention is further directed to processes for the preparat...  
WO/2009/120192
The present invention is directed to processes for the preparation of benzo-fused heteroaryl derivatives, useful for the treatment of epilepsy and related disorders. The present invention is further directed to processes for the preparat...  
WO/2009/120191
The present invention is directed to a process for the preparation of benzo-fused heteroaryl sulfamates, useful for the treatment of epilepsy and related disorders according to formula (IA) and to a crystalline compound of formula (I-S)....  
WO/2009/117829
Compounds having the general formula (I): wherein X is S, Se or NH, and stereoisomers thereof, and de-O-sulfonated analogues of all of the foregoing, but excluding naturally occurring kotalanol and de-O-sulfonated kotalanol, and methods ...  
WO/2009/111830
The present invention relates to a class of conjugated unsaturated compounds, to a method of preparing such compounds, and to the polymerisation and bio-active uses of such compounds including their use as antimicrobial agents. The inven...  
WO/2009/104722
Provided are 1) polymer compounds having excellent acid reactivity and thermal stability as well as minimal swelling during development, 2) compounds of the following formula that serve as starting materials for said polymer compounds, a...  
WO/2009/089210
The present invention is directed to novel processes for the preparation of sulfamide derivatves, useful in the treatment of epilepsy and related disorders.  
WO/2009/084773
The present invention relates to a preparation process useful in synthesis of atorvastatin, more particularly a process for preparing atorvastatin is effective in treating hyperlipemia, comprising protecting the dihydroxy group at C3 and...  
WO/2009/084773
The present invention relates to a preparation process useful in synthesis of atorvastatin, more particularly a process for preparing atorvastatin is effective in treating hyperlipemia, comprising protecting the dihydroxy group at C3 and...  
WO/2009/080834
Process for the synthesis of a cyclic diester of an alpha-hydroxyacid, comprising the following steps: an alkalino-earth salt of the corresponding alpha-hydroxyacid is mixed with said alpha-hydroxyacid and water; the mixture is treated b...  
WO/2009/077615
The present invention relates to a method for obtaining lactide by thermal cracking of lactic acid oligomers in the presence of a metal salt of the phosphite anion (PO3)3- in which the metal is chosen from the group comprising tin, alumi...  
WO/2009/077385
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing...  
WO/2009/076618
The present invention relates to, in part, novel sulfate and bisphenol compounds useful for the recognition, attachment and growth of unwanted biologies on natural and manmade surfaces. Another aspect of the invention relates to combinat...  
WO/2009/075818
Disclosed herein are methods and intermediates useful in the preparation of macrolides, e.g., compounds of formula (IV) wherein R1-R12 are as defined herein.  
WO/2009/070910
Compounds of formula (I) wherein R1- R5, n and m have the same meaning as given in the description, having cooling properties are disclosed. Furthermore a process of their production and consumer products comprising them are disclosed.  
WO/2009/072502
Disclosed is a method by which various fluorine-containing carbonate compounds can be freely produced with high yield without using phosgene and without by-producing hydrogen chloride. Specifically disclosed is a method wherein a fluorin...  
WO/2009/070910
Compounds of formula (I) wherein R1- R5, n and m have the same meaning as given in the description, having cooling properties are disclosed. Furthermore a process of their production and consumer products comprising them are disclosed.  
WO/2009/072501
Disclosed is a novel method by which various carbonate compounds can be freely produced with high yield without using phosgene and without by-producing hydrogen chloride. Specifically disclosed is a method wherein a compound having a car...  
WO/2009/065035
The invention provides novel therapeutic compounds, pharmaceutical compositions comprising these compounds, and methods for using these compounds and compositions to treat diseases and disorders, such as cancer.  

Matches 201 - 250 out of 3,589