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Matches 201 - 250 out of 7,141

Document Document Title
WO/2011/051960A2
The invention relates to processes for the preparation of compound of CCI-779 having the Formula (I), which is useful as an antineoplastic agent. The invention further relates to certain novel intermediates useful in the preparation of c...  
WO/2011/048425A1
The invention concerns a continuous process for the production of compounds having the general formula (6) comprising providing to a reaction zone a continuous stream of an alkyl acetate and a continuous stream of an alkali metal or alka...  
WO/2011/038857A8
Suggested are alkoxylated glycerol acetals according to formulae (Ia) and (Ib) in which R1 stands for a linear or branched, saturated or unsaturated and optionally substituted hydrocarbyl residue comprising 6 to 22 carbon atoms and O or ...  
WO/2011/038857A2
Suggested are alkoxylated glycerol acetals according to formulae (Ia) and (Ib) in which R1 stands for a linear or branched, saturated or unsaturated and optionally substituted hydrocarbyl residue comprising 6 to 22 carbon atoms and O or ...  
WO/2011/038857A3
Suggested are alkoxylated glycerol acetals according to formulae (Ia) and (Ib) in which R1 stands for a linear or branched, saturated or unsaturated and optionally substituted hydrocarbyl residue comprising 6 to 22 carbon atoms and O or ...  
WO/2011/038337A1
Ketal lactones of and methods for making such ketal lactones are disclosed. Also described are methods for making isolated cis- and trans- stereoisomers of hydroxyester ketals of oxocarboxylic acids and polymers having ketal units of suc...  
WO/2011/034078A1
Disclosed is a compound which is useful as the active ingredient of a medicinal composition, in particular, a medicinal composition for preventing and/or treating a VAP-1 associated disease. As the results of intensive studies on compoun...  
WO/2011/033937A1
Disclosed are: a liquid crystalline compound having stability to heat, light and the like, capable of forming a nematic phase in a broad temperature range, and having a low viscosity, high optical anisotropy, a proper elastic constant (K...  
WO/2011/027888A1
Disclosed are a diamide-phenyl derivative which inhibits soluble epoxy hydrolase (sEH), and a pharmaceutically acceptable salt of the diamide-phenyl derivative. Specifically disclosed are a compound represented by formula (I), and a phar...  
WO/2011/020536A1
The invention relates to the use of glyceraldehyde derivatives and the acetals thereof for releasing active molecules, which are skin-tanning substances, UV filters, preservatives, or coolants. The invention also relates to novel glycera...  
WO/2011/013077A1
The invention is directed to the use of compounds of formula (I), as fragrant agents. In this formula: - R3 and R4 are independently a hydrogen atom, a C1-C6 alkyl group or a C2-C6 alkenyl group, R5 is a C1-C6 alkyl group, a C2-C6 alkeny...  
WO/2011/009826A2
Chalcone derivatives of the general formula (I), wherein two from among A, B and Z which are adjacent to each other are linked and form a moiety selected from -O-(CH2)n-S(O)m-, -S(O)m-(CH2)n-O- and -O-(CH2)n-O-, and the remaining one fro...  
WO/2011/009478A1
The invention relates to a method for making a polymer wherein during the polymerisation is incorporated in the polymer chain by ring opening polymerisation a cyclic (alkyl)acryloyl carbonate having the formula (4): wherein R1 and R2 eac...  
WO/2011/009826A3
Chalcone derivatives of the general formula (I), wherein two from among A, B and Z which are adjacent to each other are linked and form a moiety selected from -O-(CH2)n-S(O)m-, -S(O)m-(CH2)n-O- and -O-(CH2)n-O-, and the remaining one fro...  
WO/2011/006566A3
The invention relates to specific monomethoxy-hydroxy-benzylmalonates having an amphiphilic-antioxidative activity profile, to methods for producing the same, to preparations and to the use thereof.  
WO/2011/003191A1
Provided are viral sensitizing compounds that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the cytotoxicity of virus to cells. Other uses, compositions ...  
WO/2010/149817A1
The present invention relates to compounds with a dioxane nucleus derived from carbohydrates and C-glucosides, to a method for obtaining same, to the use of such compounds as cytotoxic agent and antiproliferative agents, and to the use t...  
WO/2010/144959A1
The present invention relates to analogues of anti-fibrotic agents having the formula (I) with the substituents as described within the specification. The present invention also relates to methods for their preparation.  
WO/2010/146236A1
The present invention relates to sulphonamide derivatives, whith a urea moiety. The invention also relates to the use of the derivatives as inhibitors of collagen receptor integrins, especially α2β1 integrin inhibitors e.g. in connecti...  
WO/2010/136037A1
The invention relates to novel calcium-sensing receptor (CaSR) modulating substituted cyclopentylene compounds represented in formula I and derivatives thereof, to said compounds for use as a medicament, to said compounds for use in ther...  
WO/2010/134014A1
The present invention relates to bridged spiro[2.4]heptane derivatives of formula (I), wherein W, Y, Z, R1 and R2 are as defined in the description, their preparation and their use as pharmaceutically active compounds as ALX receptor and...  
WO/2010/126811A1
The present invention relates to compounds of formula (I), and pharmaceutically acceptable salts thereof, wherein R1 to R5, A, B, D and X are as defined herein. The invention also relates to pharmaceutical compositions comprising these c...  
WO/2010/123139A1
Disclosed is a long-chain fatty acid elongase (Elovl6) inhibitor, which is characterized by comprising at least one of a compound represented by formula (I), a pharmaceutically acceptable salt of the compound, and a solvate of the compou...  
WO/2010/122968A1
Disclosed is a compound useful as an anti-obesity agent. Studies have been made on compounds which have a DGAT1 inhibitory activity and are therefore promising active ingredients for pharmaceutical compositions for treating obesity, type...  
WO/2010/122451A1
The present invention relates to the field of perfumery. More particularly, it concerns some acetal derivatives of 2,2,3, 6-tetramethyl-1-cyclohexane/ene-carbaldehyde of formula (I) wherein one dotted line indicates the presence of a car...  
WO/2010/117435A3
Phenyliodonium ylide derivatives substituted with electron donating as well as electron withdrawing groups on the aromatic ring are shown for use as precursors in aromatic nucleophilic substitution reactions. The iodonium ylide group is ...  
WO/2010/117435A2
Phenyliodonium ylide derivatives substituted with electron donating as well as electron withdrawing groups on the aromatic ring are shown for use as precursors in aromatic nucleophilic substitution reactions. The iodonium ylide group is ...  
WO/2010/108856A1
Provided herein are compounds of the formula (I) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing ...  
WO/2010/108856A8
Provided herein are compounds of the formula (I) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing ...  
WO/2010/107085A1
Provided is a novel alicyclic epoxy resin which provides a cured material having excellent heat resistance, optical properties, and toughness. The epoxy resin comprises a diolefin compound represented by formula (1) as a starting materia...  
WO/2010/105143A3
An S, S- and R,R-lactide stream suitable for polymerization is prepared by producing a low molecular weight poly(lactic acid), depolymerizing the low molecular weight poly(lactic acid) to form a mixture of S, S-, R,R- and meso- lactide, ...  
WO/2010/105143A2
An S, S- and R,R-lactide stream suitable for polymerization is prepared by producing a low molecular weight poly(lactic acid), depolymerizing the low molecular weight poly(lactic acid) to form a mixture of S, S-, R,R- and meso- lactide, ...  
WO/2010/105142A1
Lactic acid equivalents are recovered from a starting lactide stream by catalytically racemizing a portion of the lactide in the stream at a temperature of 18O°C or below. This increases the proportion of two species of lactide (i.e., a...  
WO/2010/100390A1
The invention relates to a method for polymerizing 1,4-dioxane-2,5-diones in the presence of a generally protic initiator and at least one catalyst comprising at least one metal-free organic compound. The latter is a non-metal organic ca...  
WO/2010/090304A1
Disclosed is an excellent agent for treatment or prevention of dementia, schizophrenia and the like, which has a serotonin 5-HT5A receptor modulating activity. An acylguanidine derivative represented by formula (I), wherein guanidine is ...  
WO/2010/091109A3
Provided are monodisperse synthetic dendrimer calibrants for mass spectrometry. The calibrants are distinguished by their relative ease and rapidity of synthesis, comparatively low cost, long shelf life, high purity, and amenability to b...  
WO/2010/091109A2
Provided are monodisperse synthetic dendrimer calibrants for mass spectrometry. The calibrants are distinguished by their relative ease and rapidity of synthesis, comparatively low cost, long shelf life, high purity, and amenability to b...  
WO/2010/091164A1
The present invention comprises glucosylceramide synthase (GCS) modulators of following structural formula (I); wherein R1, A, L, R2, R3, and m are defined herein, as well as N-oxides of them and pharmaceutically acceptable salts thereof...  
WO/2010/087394A1
An alcohol compound useful as a starting material or intermediate for coating materials, adhesives, medicines, cosmetics, food additives, surfactants, etc., and a process for producing the compound. The alcohol compound is represented by...  
WO/2010/087430A1
An N-acyl anthranilic acid derivative represented by general formula (I) or a salt thereof is useful for prevention or treatment of diseases associated with excessive production of collagen. (In the formula, R1 represents a carboxyl grou...  
WO/2010/085377A2
The disclosure includes hydroxamic compounds of Formula I: (I) wherein P, Z, and m are defined herein. Also disclosed is a method for treating a neoplastic disease or an immune disease with these compounds.  
WO/2010/085377A3
The disclosure includes hydroxamic compounds of Formula I: (I) wherein P, Z, and m are defined herein. Also disclosed is a method for treating a neoplastic disease or an immune disease with these compounds.  
WO/2010/080537A1
GPR120 agonists are provided. These compounds are useful for the treatment of metabolic diseases, including Type II diabetes and diseases associated with poor glycemic control.  
WO/2010/079809A1
Disclosed is a glycol compound which is useful as a starting material and an intermediate for a synthetic resin, an additive for a synthetic resin, a medicine, a cosmetic, a food additive, a surfactant, etc., further disclosed is a metho...  
WO/2010/079810A1
Disclosed is a glycol compound which is useful as a starting material and an intermediate body for a synthetic resin, an additive for a synthetic resin, a medicine, a cosmetic, a food additive, a surfactant, etc., further disclosed is a ...  
WO/2010/073512A1
A method for producing glycolide which comprises: a step (1) wherein a mixture comprising a glycolic acid oligomer and a high-boiling polar organic solvent is refluxed by heating under atmospheric or reduced pressure, while conducting th...  
WO/2010/058060A1
Compounds of formula (I), wherein X, Z, A, B, D, E, R1-R4 and m are as defined in the claims, exhibit alpha2C antagonistic activity and are thus useful as alpha2C antagonists.  
WO/2010/053275A2
The present invention relates to a high-yield method for preparing highly pure (3S,4S)-4-((R)-2-(benzyloxy)tridecyl)-3-hexyl-2-oxetanone using a metal salt of (2S,3S,5R)-2-hexyl-3,5-dihydroxyhexadecanoic acid as an intermediate.  
WO/2010/053275A3
The present invention relates to a high-yield method for preparing highly pure (3S,4S)-4-((R)-2-(benzyloxy)tridecyl)-3-hexyl-2-oxetanone using a metal salt of (2S,3S,5R)-2-hexyl-3,5-dihydroxyhexadecanoic acid as an intermediate.  
WO/2010/048715A1
The invention relates to gemini surfactants of formula IA wherein A is a core derived from an organic polyhydroxy compound; R1 and R2 are each independently a hydrophobic group; and R3 and R4 are each independently a surfactant head grou...  

Matches 201 - 250 out of 7,141