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Matches 201 - 250 out of 7,039

Document Document Title
WO/2010/149817A1
The present invention relates to compounds with a dioxane nucleus derived from carbohydrates and C-glucosides, to a method for obtaining same, to the use of such compounds as cytotoxic agent and antiproliferative agents, and to the use t...  
WO/2010/144959A1
The present invention relates to analogues of anti-fibrotic agents having the formula (I) with the substituents as described within the specification. The present invention also relates to methods for their preparation.  
WO/2010/146236A1
The present invention relates to sulphonamide derivatives, whith a urea moiety. The invention also relates to the use of the derivatives as inhibitors of collagen receptor integrins, especially α2β1 integrin inhibitors e.g. in connecti...  
WO/2010/136037A1
The invention relates to novel calcium-sensing receptor (CaSR) modulating substituted cyclopentylene compounds represented in formula I and derivatives thereof, to said compounds for use as a medicament, to said compounds for use in ther...  
WO/2010/134014A1
The present invention relates to bridged spiro[2.4]heptane derivatives of formula (I), wherein W, Y, Z, R1 and R2 are as defined in the description, their preparation and their use as pharmaceutically active compounds as ALX receptor and...  
WO/2010/126811A1
The present invention relates to compounds of formula (I), and pharmaceutically acceptable salts thereof, wherein R1 to R5, A, B, D and X are as defined herein. The invention also relates to pharmaceutical compositions comprising these c...  
WO/2010/122451A1
The present invention relates to the field of perfumery. More particularly, it concerns some acetal derivatives of 2,2,3, 6-tetramethyl-1-cyclohexane/ene-carbaldehyde of formula (I) wherein one dotted line indicates the presence of a car...  
WO/2010/122968A1
Disclosed is a compound useful as an anti-obesity agent. Studies have been made on compounds which have a DGAT1 inhibitory activity and are therefore promising active ingredients for pharmaceutical compositions for treating obesity, type...  
WO/2010/123139A1
Disclosed is a long-chain fatty acid elongase (Elovl6) inhibitor, which is characterized by comprising at least one of a compound represented by formula (I), a pharmaceutically acceptable salt of the compound, and a solvate of the compou...  
WO/2010/117435A2
Phenyliodonium ylide derivatives substituted with electron donating as well as electron withdrawing groups on the aromatic ring are shown for use as precursors in aromatic nucleophilic substitution reactions. The iodonium ylide group is ...  
WO/2010/117435A3
Phenyliodonium ylide derivatives substituted with electron donating as well as electron withdrawing groups on the aromatic ring are shown for use as precursors in aromatic nucleophilic substitution reactions. The iodonium ylide group is ...  
WO/2010/108856A8
Provided herein are compounds of the formula (I) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing ...  
WO/2010/108856A1
Provided herein are compounds of the formula (I) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing ...  
WO/2010/107085A1
Provided is a novel alicyclic epoxy resin which provides a cured material having excellent heat resistance, optical properties, and toughness. The epoxy resin comprises a diolefin compound represented by formula (1) as a starting materia...  
WO/2010/105143A2
An S, S- and R,R-lactide stream suitable for polymerization is prepared by producing a low molecular weight poly(lactic acid), depolymerizing the low molecular weight poly(lactic acid) to form a mixture of S, S-, R,R- and meso- lactide, ...  
WO/2010/105143A3
An S, S- and R,R-lactide stream suitable for polymerization is prepared by producing a low molecular weight poly(lactic acid), depolymerizing the low molecular weight poly(lactic acid) to form a mixture of S, S-, R,R- and meso- lactide, ...  
WO/2010/105142A1
Lactic acid equivalents are recovered from a starting lactide stream by catalytically racemizing a portion of the lactide in the stream at a temperature of 18O°C or below. This increases the proportion of two species of lactide (i.e., a...  
WO/2010/100390A1
The invention relates to a method for polymerizing 1,4-dioxane-2,5-diones in the presence of a generally protic initiator and at least one catalyst comprising at least one metal-free organic compound. The latter is a non-metal organic ca...  
WO/2010/091164A1
The present invention comprises glucosylceramide synthase (GCS) modulators of following structural formula (I); wherein R1, A, L, R2, R3, and m are defined herein, as well as N-oxides of them and pharmaceutically acceptable salts thereof...  
WO/2010/090304A1
Disclosed is an excellent agent for treatment or prevention of dementia, schizophrenia and the like, which has a serotonin 5-HT5A receptor modulating activity. An acylguanidine derivative represented by formula (I), wherein guanidine is ...  
WO/2010/091109A3
Provided are monodisperse synthetic dendrimer calibrants for mass spectrometry. The calibrants are distinguished by their relative ease and rapidity of synthesis, comparatively low cost, long shelf life, high purity, and amenability to b...  
WO/2010/091109A2
Provided are monodisperse synthetic dendrimer calibrants for mass spectrometry. The calibrants are distinguished by their relative ease and rapidity of synthesis, comparatively low cost, long shelf life, high purity, and amenability to b...  
WO/2010/087394A1
An alcohol compound useful as a starting material or intermediate for coating materials, adhesives, medicines, cosmetics, food additives, surfactants, etc., and a process for producing the compound. The alcohol compound is represented by...  
WO/2010/087430A1
An N-acyl anthranilic acid derivative represented by general formula (I) or a salt thereof is useful for prevention or treatment of diseases associated with excessive production of collagen. (In the formula, R1 represents a carboxyl grou...  
WO/2010/085377A2
The disclosure includes hydroxamic compounds of Formula I: (I) wherein P, Z, and m are defined herein. Also disclosed is a method for treating a neoplastic disease or an immune disease with these compounds.  
WO/2010/085377A3
The disclosure includes hydroxamic compounds of Formula I: (I) wherein P, Z, and m are defined herein. Also disclosed is a method for treating a neoplastic disease or an immune disease with these compounds.  
WO/2010/079809A1
Disclosed is a glycol compound which is useful as a starting material and an intermediate for a synthetic resin, an additive for a synthetic resin, a medicine, a cosmetic, a food additive, a surfactant, etc., further disclosed is a metho...  
WO/2010/080537A1
GPR120 agonists are provided. These compounds are useful for the treatment of metabolic diseases, including Type II diabetes and diseases associated with poor glycemic control.  
WO/2010/079810A1
Disclosed is a glycol compound which is useful as a starting material and an intermediate body for a synthetic resin, an additive for a synthetic resin, a medicine, a cosmetic, a food additive, a surfactant, etc., further disclosed is a ...  
WO/2010/073512A1
A method for producing glycolide which comprises: a step (1) wherein a mixture comprising a glycolic acid oligomer and a high-boiling polar organic solvent is refluxed by heating under atmospheric or reduced pressure, while conducting th...  
WO/2010/058060A1
Compounds of formula (I), wherein X, Z, A, B, D, E, R1-R4 and m are as defined in the claims, exhibit alpha2C antagonistic activity and are thus useful as alpha2C antagonists.  
WO/2010/053275A2
The present invention relates to a high-yield method for preparing highly pure (3S,4S)-4-((R)-2-(benzyloxy)tridecyl)-3-hexyl-2-oxetanone using a metal salt of (2S,3S,5R)-2-hexyl-3,5-dihydroxyhexadecanoic acid as an intermediate.  
WO/2010/053275A3
The present invention relates to a high-yield method for preparing highly pure (3S,4S)-4-((R)-2-(benzyloxy)tridecyl)-3-hexyl-2-oxetanone using a metal salt of (2S,3S,5R)-2-hexyl-3,5-dihydroxyhexadecanoic acid as an intermediate.  
WO/2010/048715A1
The invention relates to gemini surfactants of formula IA wherein A is a core derived from an organic polyhydroxy compound; R1 and R2 are each independently a hydrophobic group; and R3 and R4 are each independently a surfactant head grou...  
WO/2010/046194A1
Cyclohexanedione compounds, which are suitable for use as herbicides.  
WO/2010/043584A1
The invention relates to the use of and mainly novel compounds of the formula (I) wherein the moieties are as defined in the description, which are useful as farnesyl pyrophosphate synthase modulators and e.g. in the treatment of prolife...  
WO/2010/043581A1
The invention relates to a method for producing cyclic carbonates by reacting a multivalent alcohol with a dialkyl carbonate in the presence of a heterogeneous catalyst, characterized in that the heterogeneous catalyst is a basic mixed o...  
WO/2010/042867A2
Disclosed are pyruvate kinase M2 activators, which are, bis sulfonamide piperazinyl compounds of Formula (I) and 2,4-disubstituted 4H-thieno[3,2-b]pyrrole-2-(substituted benzyl)pyridazin-3(2H)ones of Formula (II), wherein L and R1 to R16...  
WO/2010/041670A1
A novel alicyclic epoxy resin having no ester bond in each molecule, and a precursor of the alicyclic epoxy resin. The precursor is a diolefin compound represented by formula (1) (wherein each of the plurality of R's independently repres...  
WO/2010/042867A3
Disclosed are pyruvate kinase M2 activators, which are bis sulfonamide piperazinyl and piperidinyl compounds of Formula (I), 2,4-disubstituted 4H- thieno[3,2-c]pyrrole-2-(substituted benzyl)pyridazin-3(2H)-ones of Formula (II) and 6-(3,4...  
WO/2010/042600A2
Novel photo-activatable pro-therapeutic agents and methods for their synthesis and use are described. The photo-activatable pro-therapeutic agents are inactive pro-forms of compounds that can be activated in situ, for example, by providi...  
WO/2010/042600A3
Novel photo-activatable pro-therapeutic agents and methods for their synthesis and use are described. The photo-activatable pro-therapeutic agents are inactive pro-forms of compounds that can be activated in situ, for example, by providi...  
WO/2010/039256A1
A compound for use in treating polycystic kidney disease is represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or ...  
WO/2010/036884A1
The present disclosure relates to the preparation of acrylate, alkacrylate, allyl, and polycarbonate derivatives of hydroxy ketal esters, and uses thereof.  
WO/2010/023448A1
The present invention provides a compound of formula (I) or its salts or pharmaceutically acceptable derivatives thereof wherein; X1 is selected from a group consisting of CH2, C(=O), C(=NH), NC(=O), R1 is selected from the group consist...  
WO/2010/022966A8
The present invention relates to three variants for preparing a mixture of cyclic diesters derived from lactic acid and especially a racemate of dilactide. This can proceed, as desired, from the corresponding a-hydroxycarboxylic acids, t...  
WO/2010/022966A3
The present invention relates to three variants for preparing a mixture of cyclic diesters derived from lactic acid and especially a racemate of dilactide. This can proceed, as desired, from the corresponding a-hydroxycarboxylic acids, t...  
WO/2010/022966A2
The present invention relates to three variants for preparing a mixture of cyclic diesters derived from lactic acid and especially a racemate of dilactide. This can proceed, as desired, from the corresponding a-hydroxycarboxylic acids, t...  
WO/2010/021093A1
Provided are a novel asymmetric organic catalyst with which it is possible to realize a high optically-active yield when said catalyst is used in a small amount, and a method for producing a compound using the same. The asymmetric organi...  
WO/2010/020548A1
The present invention relates to a compound of the general formula (I) wherein R1/R2 are independently from each other lower alkyl, or form together with the N-atom to which they are attached a heterocyclic group, selected from pyrrolidi...  

Matches 201 - 250 out of 7,039