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Matches 201 - 250 out of 7,403

Document Document Title
WO/2012/000921A1
Process for the manufacture of lactide comprising heating lactic acid in the presence of at least one hygroscopic salt present in an amount of at least 1 mol per mol of lactic acid.  
WO/2012/001601A1
The invention relates to compounds, in particular phosphinic ligands of metal complexes, as well as to metal complexes including said ligands and to supported catalysts including said metal complexes or said compounds. The invention also...  
WO/2011/163671A3
Compounds derived from acetone are provided. Particularly, the compounds are derivatives of hydroxyacetone, including dimers of both 1-hydroxyacetone and 1,3-dihydroxyacetone. The hydroxy moieties on the core hydroxyacetone molecule serv...  
WO/2011/163671A2
Compounds derived from acetone are provided. Particularly, the compounds are derivatives of hydroxyacetone, including dimers of both 1-hydroxyacetone and 1,3-dihydroxyacetone. The hydroxy moieties on the core hydroxyacetone molecule serv...  
WO/2011/159219A1
Disclosed is a process for production of a cycloaliphatic carbonate from a diol, triol or polyol and a carbon dioxide source, such as a dialkyl carbonate. Said process is performed in a solvent-free medium using a N-heterocyclic carbene ...  
WO/2011/159297A1
GPR120 agonists are provided. These compounds are useful for the treatment of metabolic diseases, including Type II diabetes and diseases associated with poor glycemic control.  
WO/2011/150513A1
Anti-virally active carbanucleosides such as entecavir are prepared by a process which utilizes, throughout the synthesis, an aromatic protectant group for the hydroxyl and the alkyl hydoxy groups of the starting material, removed as the...  
WO/2011/138665A1
The present invention provides dihydroorotate dehydrogenase inhibitors of formula (I), methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of diseases or disorde...  
WO/2011/135046A1
A one pot method of preparing cyclic carbonyl compounds comprising an active pendant pentafluorophenyl carbonate group is disclosed. The cyclic carbonyl compounds can be polymerized by ring opening methods to form ROP polymers comprising...  
WO/2011/132712A1
Provided is a novel compound that is useful as a medical drug in that said compound displays strong antimicrobial activity against gram-negative bacteria such as Pseudomonas aeruginosa and drug-resistant strains thereof, on the basis of ...  
WO/2011/122666A1
Disclosed is a method for simply and efficiently producing a benzodioxane compound. The target benzodioxane compound is obtained by reacting a phenol compound with a carbonate compound in the presence of a base. This method can produce t...  
WO/2011/114220A1
Isolated compounds from adelostemma gracillimum refined fractions and compositions containing the compounds are provided by the present invention. Adelostemma gracillimum refined fractions and the extraction process thereof are also prov...  
WO/2011/105649A1
The present invention is useful as a HMG-Co A reductase inhibitor and relates to a new method for manufacturing pitavastatin hemicalcium which is used as a treatment for hyperlipidemia. More specifically, a new method for manufacturing p...  
WO/2011/104728A1
A process for the synthesis of 100% optically pure L(+) lactide catalyzed by zinc and tin metal catalysts of less than 150 micron particle size is disclosed. The L- Lactide obtained was further purified to obtain lactide of 100% optical ...  
WO/2011/103442A2
This invention relates to compounds having the structure: wherein bonds α, β, γ, δ, ω, η, χ, ε, κ, and μ are each present or absent, and R1-R18 are various substituents described herein.  
WO/2011/100608A1
The patent application relates to a method of producing a monomer component from a genetically modified polyhydroxyalkanoate (PHA) biomass, wherein the biomass is heated in the presence of a catalyst to release a monomer component from t...  
WO/2011/092564A2
Novel intermediates, process for their preparation and their use in the preparation of therapeutically effective antineoplastic agents, in particular Temsirolimus of formula (I).  
WO/2011/092564A3
Intermediates, process for their preparation and their use in the preparation of therapeutically effective antineoplastic agents, in particular Temsirolimus of formula (I).  
WO/2011/092564A4
Intermediates, process for their preparation and their use in the preparation of therapeutically effective antineoplastic agents, in particular Temsirolimus of formula (I).  
WO/2011/092564A8
Intermediates, process for their preparation and their use in the preparation of therapeutically effective antineoplastic agents, in particular Temsirolimus of formula (I).  
WO/2011/089802A1
Disclosed is a method for producing glycolide, which comprises: a step wherein a mixture containing a glycolic acid oligomer, a high boiling point polar organic solvent having a boiling point of 230-450˚C and a tin compound is heated, a...  
WO/2011/086584A3
The present invention relates to an improved process for the preparation of amide intermediates useful in the preparation of cholesterol reducing agents.  
WO/2011/084466A1
Disclosed herein are processes for preparing cyclic esters comprising unsaturated functional groups. Also disclosed are copolymers prepared from the cyclic esters. The copolymers can be used to form microparticles, polymer micelles, etc....  
WO/2011/082460A1
The present invention relates to a method for purifying light-coloured glycerol from biodiesel production, comprising a step during which a liquid phase containing an heterocyclic intermediate product, a ketal, is obtained, allowing orga...  
WO/2011/073100A1
The invention relates to novel acylmethylene-1,3-dioxolanes and acylmethylene-1,4-dioxanes of the general formula (I), in which R1, R2, R3 and n are defined as in the description, and to a novel method for the production thereof. Acylmet...  
WO/2011/071136A1
A therapeutic agent for fibromyalgia, comprising a 5-HT2C receptor agonist as an active ingredient.  
WO/2011/061277A1
Amino phenyl acetamide compounds of Formula (I):and pharmaceutically acceptable salts thereof: wherein R1, R2, R3 and Ra are as defined in the description, use of such compounds in the chemotherapy of certain parasitic protozoal infectio...  
WO/2011/059731A1
The present invention is directed to novel alkynyl derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by DPP-1.  
WO/2011/051960A3
The invention relates to processes for the preparation of compound of CCI-779 having the Formula (I), which is useful as an antineoplastic agent. The invention further relates to certain novel intermediates useful in the preparation of c...  
WO/2011/051960A2
The invention relates to processes for the preparation of compound of CCI-779 having the Formula (I), which is useful as an antineoplastic agent. The invention further relates to certain novel intermediates useful in the preparation of c...  
WO/2011/048425A1
The invention concerns a continuous process for the production of compounds having the general formula (6) comprising providing to a reaction zone a continuous stream of an alkyl acetate and a continuous stream of an alkali metal or alka...  
WO/2011/038857A8
Suggested are alkoxylated glycerol acetals according to formulae (Ia) and (Ib) in which R1 stands for a linear or branched, saturated or unsaturated and optionally substituted hydrocarbyl residue comprising 6 to 22 carbon atoms and O or ...  
WO/2011/038857A2
Suggested are alkoxylated glycerol acetals according to formulae (Ia) and (Ib) in which R1 stands for a linear or branched, saturated or unsaturated and optionally substituted hydrocarbyl residue comprising 6 to 22 carbon atoms and O or ...  
WO/2011/038857A3
Suggested are alkoxylated glycerol acetals according to formulae (Ia) and (Ib) in which R1 stands for a linear or branched, saturated or unsaturated and optionally substituted hydrocarbyl residue comprising 6 to 22 carbon atoms and O or ...  
WO/2011/038337A1
Ketal lactones of and methods for making such ketal lactones are disclosed. Also described are methods for making isolated cis- and trans- stereoisomers of hydroxyester ketals of oxocarboxylic acids and polymers having ketal units of suc...  
WO/2011/034078A1
Disclosed is a compound which is useful as the active ingredient of a medicinal composition, in particular, a medicinal composition for preventing and/or treating a VAP-1 associated disease. As the results of intensive studies on compoun...  
WO/2011/033937A1
Disclosed are: a liquid crystalline compound having stability to heat, light and the like, capable of forming a nematic phase in a broad temperature range, and having a low viscosity, high optical anisotropy, a proper elastic constant (K...  
WO/2011/027888A1
Disclosed are a diamide-phenyl derivative which inhibits soluble epoxy hydrolase (sEH), and a pharmaceutically acceptable salt of the diamide-phenyl derivative. Specifically disclosed are a compound represented by formula (I), and a phar...  
WO/2011/020536A1
The invention relates to the use of glyceraldehyde derivatives and the acetals thereof for releasing active molecules, which are skin-tanning substances, UV filters, preservatives, or coolants. The invention also relates to novel glycera...  
WO/2011/013077A1
The invention is directed to the use of compounds of formula (I), as fragrant agents. In this formula: - R3 and R4 are independently a hydrogen atom, a C1-C6 alkyl group or a C2-C6 alkenyl group, R5 is a C1-C6 alkyl group, a C2-C6 alkeny...  
WO/2011/009826A2
Chalcone derivatives of the general formula (I), wherein two from among A, B and Z which are adjacent to each other are linked and form a moiety selected from -O-(CH2)n-S(O)m-, -S(O)m-(CH2)n-O- and -O-(CH2)n-O-, and the remaining one fro...  
WO/2011/009478A1
The invention relates to a method for making a polymer wherein during the polymerisation is incorporated in the polymer chain by ring opening polymerisation a cyclic (alkyl)acryloyl carbonate having the formula (4): wherein R1 and R2 eac...  
WO/2011/009826A3
Chalcone derivatives of the general formula (I), wherein two from among A, B and Z which are adjacent to each other are linked and form a moiety selected from -O-(CH2)n-S(O)m-, -S(O)m-(CH2)n-O- and -O-(CH2)n-O-, and the remaining one fro...  
WO/2011/006566A3
The invention relates to specific monomethoxy-hydroxy-benzylmalonates having an amphiphilic-antioxidative activity profile, to methods for producing the same, to preparations and to the use thereof.  
WO/2011/003191A1
Provided are viral sensitizing compounds that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the cytotoxicity of virus to cells. Other uses, compositions ...  
WO/2010/149817A1
The present invention relates to compounds with a dioxane nucleus derived from carbohydrates and C-glucosides, to a method for obtaining same, to the use of such compounds as cytotoxic agent and antiproliferative agents, and to the use t...  
WO/2010/144959A1
The present invention relates to analogues of anti-fibrotic agents having the formula (I) with the substituents as described within the specification. The present invention also relates to methods for their preparation.  
WO/2010/146236A1
The present invention relates to sulphonamide derivatives, whith a urea moiety. The invention also relates to the use of the derivatives as inhibitors of collagen receptor integrins, especially α2β1 integrin inhibitors e.g. in connecti...  
WO/2010/136037A1
The invention relates to novel calcium-sensing receptor (CaSR) modulating substituted cyclopentylene compounds represented in formula I and derivatives thereof, to said compounds for use as a medicament, to said compounds for use in ther...  
WO/2010/134014A1
The present invention relates to bridged spiro[2.4]heptane derivatives of formula (I), wherein W, Y, Z, R1 and R2 are as defined in the description, their preparation and their use as pharmaceutically active compounds as ALX receptor and...  

Matches 201 - 250 out of 7,403