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Matches 1 - 50 out of 7,802

Document Document Title
WO/2019/075195A1
The present disclosure provides processes for preparing (+)-pleuromutilin and synthetic (+)-pleuromutilin produced therefrom. Also provided are intermediates prepared thereby and processes for preparing these intermediates.  
WO/2019/067543A1
The present disclosure relates to compounds that are capable penetrating to the blood brain barrier to modulate the activity of EGFR tyrosine kinase. The disclosure further relates to methods of treating Glioblastoma and other EGFR media...  
WO/2019/054634A1
The present invention provides a novel heterocyclic compound and an organic light-emitting device using same.  
WO/2019/043610A1
The present invention relates to novel heterocyclic compounds of the general formula (I) their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, enantiomers, diastereomers and polymorphs. The invention also relates...  
WO/2019/039290A1
Provided are: an actinic ray-sensitive or radiation-sensitive resin composition that has excellent resolution, exposure latitude, and pattern shape properties; and a resist film, a pattern-forming method, a method for producing an electr...  
WO/2019/037862A1
The invention relates to organosulphur compounds which can be obtained from rose oxide, to methods for producing said organosulphur compounds and their use as odorants, flavourings or constituents of odorant mixtures and the products der...  
WO/2019/032126A1
Processes for preparing heteroatom containing cyclic dimers that result in increased production efficiency and reduced waste production.  
WO/2019/014748A1
Methods for prevention and treatment of asthma attacks involve the administration of one or more TRPV1 antagonists, one or more LPAr antagonists or preferably a combination of one or more TRPV1 antagonists and one or more LPAr antagonist...  
WO/2019/009956A1
Provided herein are methods for preparing ketone-containing organic molecules. The methods are based on novel iron/copper-mediated ("Fe/Cu-mediated") coupling reactions. The Fe/Cu-mediated coupling reaction can be used in the preparation...  
WO/2018/236913A1
Small molecule calpain modulator compositions and pharmaceutical compositions can be prepared and used as therapeutic agents. Exemplary compositions include non-macrocyclic a-keto amide derivatives. The therarapeutic agents can be used f...  
WO/2018/230322A1
The compound of the present invention is represented by formula (i), in particular, represented by formula (i) in which Ki1 has a structure represented by any of formulae (K-1) to (K-3). This compound, when used in a liquid-crystal compo...  
WO/2018/225018A1
The present invention relates to novel heterocyclic compounds of the general formula (I) their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, enantiomers, diastereomers and polymorphs. The invention also relates...  
WO/2018/220020A2
The invention relates to resorcinol-derived compounds of formula (I) and also the salts thereof, the solvates thereof and the optical and/or geometrical isomers thereof, including enantiomers and diastereoisomers, the racemic mixtures th...  
WO/2018/222444A1
Embodiments of the disclosure relate to methods of selectively depositing organic and hybrid organic/inorganic layers. More particularly, embodiments of the disclosure are directed to methods of modifying hydroxyl terminated surfaces for...  
WO/2018/212463A1
The present invention relates to a novel compound and an organic electroluminescent element including the same. According to the present invention, the compound is used for an organic layer of the organic electroluminescent element, pref...  
WO/2018/193090A2
Process for preparation of eliglustat hemitartrate and intermediates thereof Processes for preparation of eliglustat hemitartrate and intermediates thereof are provided. A stable amorphous form of eliglustat hemitartrate pharmaceutical c...  
WO/2018/193090A3
Process for preparation of eliglustat hemitartrate and intermediates thereof Processes for preparation of eliglustat hemitartrate and intermediates thereof are provided. A stable amorphous form of eliglustat hemitartrate pharmaceutical c...  
WO/2018/176884A1
Disclosed is a method for producing optically pure L-/D-lactide with an all-green closed cycle process, with an aqueous L-/D-lactic acid solution and polylactic acid, which is produced as a by-product, being used as raw materials, wherei...  
WO/2018/172423A1
The invention relates to a compound which is an indane derivative according to Formula (I), or a pharmaceutically acceptable salt thereof, [FORMULA (I)] wherein R1, R2, R3, n, R4, p¸ q, L, ׇ, X and m are as defined herein. The compound...  
WO/2018/171942A1
It is disclosed a process for obtaining phenolic derivatives with high industrial interest in the pharmaceutical industry by using glycerol carbonate. Specifically, the process provides for a phenol substituted in position 2 to react wit...  
WO/2018/171173A1
The present invention relates to a method for synthesis of Eliglustat and intermediate compounds thereof. Specifically, the present invention relates to the field of synthesis of organic compounds, to a method for synthesis of Eliglustat...  
WO/2018/167800A1
The present invention relates to fused bicyclic compounds that are inhibitors of GPR91, their stereoisomers, tautomers, prodrugs, polymorphs, solvates, pharmaceutically acceptable salts, and pharmaceutical compositions containing them. T...  
WO/2018/167143A1
A process for preparing a cyclic diester or a cyclic diamide by reacting a hydroxycarboxylic acid or amide with an acidic BEA (H-beta polymorph A) type zeolite. The process is characterised in that the total amount of acid sites is in th...  
WO/2018/154519A1
The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compo...  
WO/2018/154493A1
The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compo...  
WO/2018/157043A1
Disclosed are oxazolidinone compounds of Formula I: (I) salts thereof, antibacterial pharmaceutical compositions containing them, and use of the compounds to inhibit bacterial growth in mammals, including humans.  
WO/2018/141759A1
The invention relates to compounds of formula (I), wherein R1, L1, L2 and X have the meanings defined in claim 1, to a method for the production thereof, to liquid-crystalline media containing at least one compound of formula (I), and to...  
WO/2018/140738A1
Provided are compounds of Formula I, or pharmaceutically acceptable salts thereof, which are activators of nuclear factor erythroid 2 (NF-E2) -related factor 2 (Nrf2) and are useful to treat diseases caused by oxidative stress, such as n...  
WO/2018/139107A1
Provided is a method for producing a high-purity α-hydroxycarboxylic acid dimer cyclic ester while preventing α-hydroxycarboxylic acid oligomers from becoming heavy. The α-hydroxycarboxylic acid dimer cyclic ester is obtained by carry...  
WO/2018/124148A1
The purpose of the present invention relates to providing a novel glyceric acid ester which can be produced at a high yield and for which use as a synthesis intermediate can be expected, and a method for producing same. The purpose of th...  
WO/2018/124149A1
The purpose of the present invention is to provide a method for producing glyceric acid ester that enables easy, high-yield production and makes it easy to reuse pyridines that are used for a reaction. Provided is a method for producing ...  
WO/2018/124147A1
The present invention relates to a method for manufacturing 1,3-dioxane-5-ones by a short and simple method from raw materials that can be obtained easily and inexpensively, using 1,3-dioxane, which is a mixture with 1,3-dioxalans, as a ...  
WO/2018/109714A3
Bis-cyclic carbonate molecule consisting of at least two (l,3)-dioxine-2-one structures directly linked to each other or indirectly linked via other cycles.  
WO/2018/109714A2
Bis-cyclic carbonate molecule consisting of at least two (l,3)-dioxine-2-one structures directly linked to each other or indirectly linked via other cycles.  
WO/2018/105237A1
A novel method for producing a trioxopropane compound is provided. The present invention provides a method for producing a trioxopropane compound represented by general formula (1), the method being characterized by reacting a dioxopropa...  
WO/2018/100016A1
The present invention relates to 1-fluorocyclohexyl-methoxy-aryl compounds of formula (I), in which R1, R2, A1, A2, m and n are defined as indicated in claim 1, to their production, to their use as components in liquid crystal media and ...  
WO/2018/100515A1
The invention relates to novel ruthenium complexes of formula (9). The invention also relates to the method for preparation of novel metal complexes of formula (9) and their use in olefin metathesis reactions.  
WO/2018/087126A1
The present invention relates to amido-substituted cyclohexane compounds of general formula (I), in which A, R4, R6, R7, R8, R9, R10 and R11 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful ...  
WO/2018/088182A1
A method for recovering lactide, the method comprising holding a lactide-containing resin mixture at a reduced pressure to gasify the lactide contained in the resin mixture, introducing, with evacuation, a gas mixture including the resul...  
WO/2018/079333A1
The present invention provides a spontaneous alignment assistant for liquid crystal compositions, which is capable of ensuring storage stability if added to a liquid crystal composition, while enabling vertical alignment of liquid crysta...  
WO/2018/075275A1
Disclosed are of the protected photoinitiators of the formula: wherein Aryl1 is an aromatic or heteroaromatic ring; Aryl2 is an aromatic ring; each R1 is an alkyl, an aryl, an electron donating group or an electron withdrawing group, and...  
WO/2018/065387A1
The present invention relates to hamamelitannin analogues, pharmaceutical compositions comprising the same, and combinations thereof with anti-microbial agents such as antibiotics or disinfectants. It in particular relates to the use of ...  
WO/2018/059372A1
The present invention relates to a group of derivatives synthesized based on the ent-kaurane diterpenoid flexicaulin A and the methods to synthesize such diterpenoid derivatives. In particular, the chemical entities of such synthetic dit...  
WO/2018/062729A1
The present invention relates to a pseudo-ceramide compound and a preparation method therefor. According to the present invention, the pseudo-ceramide compound has a molecular structure and a function similar to those of a natural cerami...  
WO/2018/055170A1
The invention relates to a process for preparing cyclic esters by means of a transesterification reaction in the gas phase, comprising the steps of: (i) vaporizing a liquid solution of alpha-hydroxy esters, (ii) passing the ester vapors ...  
WO/2018/051278A3
The present invention relates to a compound of formula (I) based on enamine derivatives and used as organic hole conductors or hole transporting material in an optoelectronic or photoelectrochemical device. The present invention relates ...  
WO/2018/051278A4
The present invention relates to a compound of formula (I) based on enamine derivatives and used as organic hole conductors or hole transporting material in an optoelectronic or photoelectrochemical device. The present invention relates ...  
WO/2018/051278A2
The present invention relates to a compound of formula (I) based on enamine derivatives and used as organic hole conductors or hole transporting material in an optoelectronic or photoelectrochemical device. The present invention relates ...  
WO/2018/045941A1
A method for synthesizing glycolide, comprising: forming a binary composite catalytic system using a nontoxic cyclic organic guanidine compound and a nontoxic linear organic guanidine compound; and synthesizing high-purity (≥ 99.9%) gl...  
WO/2018/045938A1
A crude cyclic ester purification method. The present invention provides a quick, efficient, and green crude cyclic ester purification method, comprising three procedures of granulation, washing and separation, and drying. Only water is ...  

Matches 1 - 50 out of 7,802