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Matches 1 - 50 out of 7,858

Document Document Title
WO/2019/173772A1
The present disclosure is directed to l-(2-hydroxy-4-methylcyclohexyl)-ethanone derivatives having unique and desired flavor and/or fragrance characteristics, as well as the synthesis and application of the derivatives. The compounds of ...  
WO/2019/172361A1
According to this method for producing a cyclic ester, a mixture (I) that contains an aliphatic polyester, a specific polyalkylene glycol diether, and a sulfonic acid compound which serves as a thermal stabilizer is prepared and is subse...  
WO/2019/165687A1
A photo-alignment material, a liquid crystal display panel and a preparation method therefor. A chemical structural formula of the photo-alignment material comprises a first group, a second group, a third group, and a fourth group which ...  
WO/2018/140738A8
Provided are compounds of Formula I, or pharmaceutically acceptable salts thereof, which are activators of nuclear factor erythroid 2 (NF-E2) -related factor 2 (Nrf2) and are useful to treat diseases caused by oxidative stress, such as n...  
WO/2019/151384A1
One embodiment of the present invention relates to novel substances, etc., which are: [1] a compound, etc., represented by formula (A1) or formula (B1); [2] a compound, etc., represented by formula (A2) or formula (B2); [3] a compound, e...  
WO/2019/145719A1
The present invention relates to compounds of Formula I as defined herein, and salts and solvates thereof. (I) The present invention also relates to pharmaceutical compositions comprising compounds of Formula (I), and to compounds of For...  
WO/2019/145718A1
The present invention relates to compounds of Formula I as defined herein, and salts and solvates thereof. (I) The present invention also relates to pharmaceutical compositions comprising compounds of Formula(I), and to compounds of Form...  
WO/2019/128918A1
Disclosed in the present invention are an aromatic vinyl or aromatic ethyl derivative, a preparation method therefor, an intermediate, a pharmaceutical composition, and an application. The aromatic vinyl or aromatic ethyl derivative in t...  
WO/2019/120101A1
Disclosed is a compound having the structure of formula I. Also disclosed is a liquid crystal composition comprising the compound of formula I, and a photoelectric display component comprising the liquid crystal composition. The compound...  
WO/2019/124092A1
The present invention provides: a compound represented by formula (i), a liquid crystal composition using said compound, and a liquid crystal display device using said liquid crystal composition. The compound represented by formula (i) h...  
WO/2019/123476A1
The present invention relates to pharmaceutical compositions of Eliglustat. In particular the present invention relates to stable amorphous Eliglustat premix having enhanced stability and dissolution properties. The present invention als...  
WO/2019/124345A1
The present invention addresses the problem of providing: a polymerizable liquid crystal composition that satisfies the demand for the high-speed response, low-voltage drive, high contrast, long-term reliability, and the like that have h...  
WO/2019/108033A1
The present specification provides a compound represented by chemical formula 1, and an organic light emitting element comprising the same.  
WO/2019/101059A1
A compound having the structure shown in formula I, a liquid crystal composition comprising the compound having the structure shown in formula I, and an electro-optical display device comprising the liquid crystal composition. The compou...  
WO/2019/099457A1
Provided herein are benzodioxinone compounds of Formula I that are useful as inhibitors of ACC1 and/or ACC2. The benzodioxinone compounds described herein can be used for treating a disease or disorder associated with aberrant ACC1 and/o...  
WO/2019/090085A1
Provided herein are compounds of formula (I), compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases, disorders and conditions. (Formula I).  
WO/2019/082209A1
The present invention related to stable N-((1R, 2R)-1-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)- 1-hydroxy-3- (pyrrolidin-1-yl)propan-2-yl) octanamide (2R,3R)- 2,3-dihydroxysuccinate premix of formula (Ia) and its process for preparation th...  
WO/2019/078462A1
The present invention provides a novel heterocyclic compound and an organic light-emitting device using same.  
WO/2019/076343A1
Disclosed are a PD-1/PD-L1 small-molecule inhibitor and a preparation method therefor and use thereof. In particular, disclosed are a compound which has a structure as shown in formula L, a stereoisomer or a tautomer thereof, or a pharma...  
WO/2019/078443A1
The present invention provides a novel compound and an organic light emitting device using the same.  
WO/2019/075195A1
The present disclosure provides processes for preparing (+)-pleuromutilin and synthetic (+)-pleuromutilin produced therefrom. Also provided are intermediates prepared thereby and processes for preparing these intermediates.  
WO/2019/067543A1
The present disclosure relates to compounds that are capable penetrating to the blood brain barrier to modulate the activity of EGFR tyrosine kinase. The disclosure further relates to methods of treating Glioblastoma and other EGFR media...  
WO/2019/054634A1
The present invention provides a novel heterocyclic compound and an organic light-emitting device using same.  
WO/2019/043610A1
The present invention relates to novel heterocyclic compounds of the general formula (I) their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, enantiomers, diastereomers and polymorphs. The invention also relates...  
WO/2019/039290A1
Provided are: an actinic ray-sensitive or radiation-sensitive resin composition that has excellent resolution, exposure latitude, and pattern shape properties; and a resist film, a pattern-forming method, a method for producing an electr...  
WO/2019/037862A1
The invention relates to organosulphur compounds which can be obtained from rose oxide, to methods for producing said organosulphur compounds and their use as odorants, flavourings or constituents of odorant mixtures and the products der...  
WO/2019/032126A1
Processes for preparing heteroatom containing cyclic dimers that result in increased production efficiency and reduced waste production.  
WO/2019/014748A1
Methods for prevention and treatment of asthma attacks involve the administration of one or more TRPV1 antagonists, one or more LPAr antagonists or preferably a combination of one or more TRPV1 antagonists and one or more LPAr antagonist...  
WO/2019/009956A1
Provided herein are methods for preparing ketone-containing organic molecules. The methods are based on novel iron/copper-mediated ("Fe/Cu-mediated") coupling reactions. The Fe/Cu-mediated coupling reaction can be used in the preparation...  
WO/2018/193090A3
Process for preparation of eliglustat hemitartrate and intermediates thereof Processes for preparation of eliglustat hemitartrate and intermediates thereof are provided. A stable amorphous form of eliglustat hemitartrate pharmaceutical c...  
WO/2018/236913A1
Small molecule calpain modulator compositions and pharmaceutical compositions can be prepared and used as therapeutic agents. Exemplary compositions include non-macrocyclic a-keto amide derivatives. The therarapeutic agents can be used f...  
WO/2018/230322A1
The compound of the present invention is represented by formula (i), in particular, represented by formula (i) in which Ki1 has a structure represented by any of formulae (K-1) to (K-3). This compound, when used in a liquid-crystal compo...  
WO/2018/225018A1
The present invention relates to novel heterocyclic compounds of the general formula (I) their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, enantiomers, diastereomers and polymorphs. The invention also relates...  
WO/2018/220020A2
The invention relates to resorcinol-derived compounds of formula (I) and also the salts thereof, the solvates thereof and the optical and/or geometrical isomers thereof, including enantiomers and diastereoisomers, the racemic mixtures th...  
WO/2018/222444A1
Embodiments of the disclosure relate to methods of selectively depositing organic and hybrid organic/inorganic layers. More particularly, embodiments of the disclosure are directed to methods of modifying hydroxyl terminated surfaces for...  
WO/2018/212463A1
The present invention relates to a novel compound and an organic electroluminescent element including the same. According to the present invention, the compound is used for an organic layer of the organic electroluminescent element, pref...  
WO/2018/193090A2
Process for preparation of eliglustat hemitartrate and intermediates thereof Processes for preparation of eliglustat hemitartrate and intermediates thereof are provided. A stable amorphous form of eliglustat hemitartrate pharmaceutical c...  
WO/2018/176884A1
Disclosed is a method for producing optically pure L-/D-lactide with an all-green closed cycle process, with an aqueous L-/D-lactic acid solution and polylactic acid, which is produced as a by-product, being used as raw materials, wherei...  
WO/2018/172423A1
The invention relates to a compound which is an indane derivative according to Formula (I), or a pharmaceutically acceptable salt thereof, [FORMULA (I)] wherein R1, R2, R3, n, R4, p¸ q, L, ׇ, X and m are as defined herein. The compound...  
WO/2018/171942A1
It is disclosed a process for obtaining phenolic derivatives with high industrial interest in the pharmaceutical industry by using glycerol carbonate. Specifically, the process provides for a phenol substituted in position 2 to react wit...  
WO/2018/171173A1
The present invention relates to a method for synthesis of Eliglustat and intermediate compounds thereof. Specifically, the present invention relates to the field of synthesis of organic compounds, to a method for synthesis of Eliglustat...  
WO/2018/167800A1
The present invention relates to fused bicyclic compounds that are inhibitors of GPR91, their stereoisomers, tautomers, prodrugs, polymorphs, solvates, pharmaceutically acceptable salts, and pharmaceutical compositions containing them. T...  
WO/2018/167143A1
A process for preparing a cyclic diester or a cyclic diamide by reacting a hydroxycarboxylic acid or amide with an acidic BEA (H-beta polymorph A) type zeolite. The process is characterised in that the total amount of acid sites is in th...  
WO/2018/154519A1
The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compo...  
WO/2018/154493A1
The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compo...  
WO/2018/157043A1
Disclosed are oxazolidinone compounds of Formula I: (I) salts thereof, antibacterial pharmaceutical compositions containing them, and use of the compounds to inhibit bacterial growth in mammals, including humans.  
WO/2018/141759A1
The invention relates to compounds of formula (I), wherein R1, L1, L2 and X have the meanings defined in claim 1, to a method for the production thereof, to liquid-crystalline media containing at least one compound of formula (I), and to...  
WO/2018/140738A1
Provided are compounds of Formula I, or pharmaceutically acceptable salts thereof, which are activators of nuclear factor erythroid 2 (NF-E2) -related factor 2 (Nrf2) and are useful to treat diseases caused by oxidative stress, such as n...  
WO/2018/109714A3
Bis-cyclic carbonate molecule consisting of at least two (l,3)-dioxine-2-one structures directly linked to each other or indirectly linked via other cycles.  
WO/2018/139107A1
Provided is a method for producing a high-purity α-hydroxycarboxylic acid dimer cyclic ester while preventing α-hydroxycarboxylic acid oligomers from becoming heavy. The α-hydroxycarboxylic acid dimer cyclic ester is obtained by carry...  

Matches 1 - 50 out of 7,858