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Matches 1 - 50 out of 20,732

Document Document Title
WO/2019/159596A1
Provided is a method for preparing a coupled body represented by general formula (3), the coupled body being obtained by reacting a compound represented by general formula (1) and a compound represented by general formula (2) in the pres...  
WO/2019/160315A1
The present invention relates to a heterocyclic compound of formula 1 and an organic light emitting device comprising the same.  
WO/2019/157020A1
In one aspect, the disclosure relates to relates to substituted benzothiophene analogs which are useful as selective degraders of estrogen receptor, methods of making same, pharmaceutical compositions comprising same, and methods of trea...  
WO/2019/153954A1
Disclosed are a multi-substituted benzene compound having biological activity, a preparation method therefor, and an application thereof. The compound of the present invention has good biological activity and the activity of inhibiting t...  
WO/2019/154412A1
Provided are a new antimicrobial agent compound as shown in the following general formula (I), a pharmaceutically acceptable salt thereof, an ester thereof, a prodrug thereof, a solvate thereof, a deuterated compound thereof, or a stereo...  
WO/2019/153373A1
Disclosed is a method for synthesizing a 2-benzylidene tetrahydrothiophene derivative, the method comprising the following step: reacting a (cyclopropyl ethynyl) aromatic cyclic compound as shown in formula (I) with a sulfur source under...  
WO/2019/154949A1
The present invention relates to a new class of fused thiophene derivatives and their uses for treating diseases such as infection, cancer, metabolic diseases, cardiovascular diseases, iron storage disorders and inflammatory disorders.  
WO/2019/154974A1
The present invention discloses thermally stable free thiophene croconaine dyes of formula (I), where R1-R4 are 1-20C alkyl or alkenyl groups, and their even more thermally stable complexes with anthracenyl-tetralactam macro molecules, w...  
WO/2019/154950A1
The present invention relates to a new class of fused thiophene derivatives and their uses for treating diseases such as infection, cancer, metabolic diseases, cardiovascular diseases, iron storage disorders and inflammatory disorders.  
WO/2019/147074A1
The present invention provides a novel heterocyclic compound and an organic light emitting device using the same.  
WO/2019/143529A1
Engineered promiscuous biotin ligases and methods of using them in proximity labeling are described. In particular, the invention provides novel biotin ligase variants having increased promiscuous biotinylation activity capable of proxim...  
WO/2019/141229A1
The present invention involves compounds as PPAR agonists and applications thereof. The compounds involved are novel peroxisome proliferator-activated receptor (PPAR) γ receptor agonists and can inhibit the production of mitochondrial r...  
WO/2019/144132A1
Described herein are compounds that are estrogen receptor modulators of formula I' Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen rece...  
WO/2019/143057A1
The present invention provides an acridine derivative represented by chemical formula (1) and an organic light-emitting diode comprising same.  
WO/2019/128849A1
The present invention relates to an organic compound and application thereof in an organic electronic device, especially organic electroluminescent diodes. The present invention further relates to an organic electronic device comprising ...  
WO/2019/131922A1
The present invention provides a compound that has β2-adrenergic receptor antagonist activity and carbonic anhydrase-inhibitory activity, and that exhibits excellent ocular antihypertensive activity. Specifically provided is a compound ...  
WO/2019/122265A1
The present application relates to compounds of formula (I') or formula (I), such as formula (Ia), and their pharmaceutical compositions/preparations. This application further relates to methods of treating or preventing neurodegenerativ...  
WO/2019/124537A1
Provided is an agricultural and horticultural fungicide manifesting a high control effect against a wide range of plant pathogens. The compound represented by formula (1): (in the formula, each symbol is as described in the specification...  
WO/2019/124261A1
Provided is a Rotigotine-containing patch having a support layer and an adhesive layer, wherein the adhesive layer contains Rotigotine and/or a pharmaceutically acceptable salt thereof, and further contains a styrene-based thermoplastic ...  
WO/2019/124538A1
Provided is an agricultural and horticultural fungicide exhibiting a high control effect against a wide range of plant pathogens. A compound represented by formula (1) or a salt thereof (in the formula, each symbol is as defined in the d...  
WO/2019/124903A1
An organic light emitting device comprising a compound represented by formula 1 as a light emitting auxiliary layer material and an electronic device comprising the same are disclosed. As the compound represented by formula 1 is comprise...  
WO/2019/122151A1
The present invention relates a compound of formula (I) in Z-isomer form (Z-(l)) or a compound of formula (I) in E-isomer form (E-(l)) wherein: R2 is a radical of formula (II) and of formula (III); X1, X2, X3, X4 and X5 are CR3 and N; Y1...  
WO/2019/120099A1
The present invention relates to an organic mixture and the use thereof in an organic electronic device. The organic mixture comprises organic materials H1 and H2, wherein H1 is a compound as shown in the following general formula (1), a...  
WO/2019/115577A1
The present application relates to a specific fluorene derivative, to its use in an electronic device and to an electronic device comprising said fluorene derivatives. Further, the present application relates to a process for the prepara...  
WO/2019/115781A1
The present invention relates to compounds suitable for treating, ameliorating and/or preventing neuromuscular disorders, including the reversal of drug-induced neuromuscular blockade. The compounds as defined herein preferably inhibit t...  
WO/2019/110427A1
Compounds of the formula (I) wherein the subsitiuents are as defined in claim 1. Furthermore, the present invention relates to agrochemical compositions which comprise compounds of formula (I), to preparation of these compositions, and t...  
WO/2018/151861A9
Provided herein are methods for determining if a compound has potential efficacy for the treatment for a specific symptom domain of schizophrenia, such as for example, the treatment of a negative symptom of schizophrenia. In addition, pr...  
WO/2019/110137A1
The present invention relates to o-phenoxy and o-benzyloxypropylamino derivatives (I) having pharmacological activity towards the α2δ subunit, in particular the a2S-1 subunit, of the voltage-gated calcium channel, to processes of prepa...  
WO/2019/109458A1
Disclosed are an organic monomolecular white light material, a preparation method therefor, and an OLED device. The organic monomolecular white light material has room temperature phosphorescence emission properties in a solid state, and...  
WO/2019/107394A1
The present invention addresses the problem of providing a liquid crystal compound that satisfies at least one physical property including a low minimum temperature for the liquid crystal phase, a low viscosity, a suitable optical anisot...  
WO/2019/105234A1
The present invention relates to an aromatic compound, a pharmaceutical composition comprising the compound, and a method for preparing the compound and an intermediate thereof. The present invention further relates to use of the compoun...  
WO/2019/108800A1
The invention relates to compounds that promote hematopoietic regeneration. The invention further relates to methods of promoting hematopoietic regeneration using the novel compounds of the invention.  
WO/2019/106029A1
The present invention relates to norbornadiene compounds (Formula I), and the corresponding quadricyclane compounds (Formula III). The compounds are to be included in a molecular thermal systems (MOST), and to be used for storing solar e...  
WO/2019/102054A1
Non-glycosidic analogues of alpha-galactosylceramide of formula (I), wherein A, Z, Ra, Rb and Rc have the meaning indicated in the description, as NKT cell activators.  
WO/2019/098796A1
The present specification provides a compound represented by chemical formula 1, and an organic light-emitting device comprising same.  
WO/2019/098773A1
The present specification provides a compound represented by chemical formula 1, and an organic light-emitting device comprising same.  
WO/2019/087548A1
Provided is a fluorine-containing ether compound which is capable of forming a lubricating layer that has excellent wear resistance even if the thickness thereof is thin, and which is suitable as a material for a lubricant for magnetic r...  
WO/2019/086707A1
The present invention relates to a method of reducing the number or percentage of pluripotent stem cells or of enriching differentiating or differentiated cells in a cell population comprising pluripotent stem cells and differentiating c...  
WO/2019/087028A1
Provided are IDO1 inhibitor compounds of Formula (I) and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases.  
WO/2019/087129A1
The invention relates to compounds of formula I and pharmaceutical compositions containing them. Also, the invention relates to methods for expanding stem cells and/or progenitor cells and methods for treating a hematopoietic disorder/ma...  
WO/2019/080882A1
Disclosed are a compound as shown in formula (I), a pharmaceutical composition comprising the compound of formula (I), and the use of the compound and pharmaceutical composition in the preparation of an HDAC inhibitor drug. The compound ...  
WO/2019/083215A1
The present invention relates to a novel compound and an organic electroluminescent device comprising same. The compound, according to the present invention, is used for an organic layer, preferably, a light-emitting layer, of an organic...  
WO/2019/081346A1
A process for preparing the benzothiophen-2-yl boronate of formula (VI) which serves as an intermediate for production of medicaments and for production of medicaments for treatment and/or prophylaxis of proliferative disorders, such as ...  
WO/2019/076709A1
The present invention provides compounds of formulae (1) (2) wherein R1and R2are C1-30alkyl, C2-3O-alkenyl, C2-30-alkynyl, C5-7-cycloalkyl, C6-14-aryl or 5 to 14 membered heteroaryl, wherein C1-30-alkyl, C2-3O-alkenyl and C2-3O-alkynyl c...  
WO/2019/077106A1
The present invention relates to new compounds of general formula (I) showing great affinity and activity towards the subunit α2δ of voltage-gated calcium channels (VGCC), especially the α2δ-1 subunit of voltage-gated calcium channel...  
WO/2019/076343A1
Disclosed are a PD-1/PD-L1 small-molecule inhibitor and a preparation method therefor and use thereof. In particular, disclosed are a compound which has a structure as shown in formula L, a stereoisomer or a tautomer thereof, or a pharma...  
WO/2019/076904A1
The application relates to compounds of formula (I) that show great affinity and activity towards the subunit α2δ of voltage-gated calcium channels (VGCC), especially the α2δ-1 subunit of voltage-gated calcium channels or dual activi...  
WO/2019/076852A1
The present invention relates to dibenzofuans and dibenzothiophenes thiophenesof formula (l) in which the occurring groups and parameters have the meanings as indicated in claim 1, to liquid-crystalline media comprising same and to high-...  
WO/2019/078246A1
Provided is a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, which is useful as an IDO/TDO inhibitor. The compound represented by formula (I) or a pharmaceutically acceptable salt thereof can, for exam...  
WO/2019/061299A1
Provided is a one-step amination reaction for producing an aminomethyl substituted heterocycloalkane, notably (tetrahydrofuran-2, 5-diyl) dimethanamine.  

Matches 1 - 50 out of 20,732