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JP3960481B2 |
The invention relates to compounds of formula: wherein R1 is selected from the group consisting of fatty acid acyl groups of 12 to 30 carbon atoms and fatty alcohol groups of 12 to 30 carbon atoms, and wherein R2 is selected from the gro...
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JP3954671B2 |
To provide a method for producing 2,5-bis(isocyanatomethyl)-1,4-dithian by which the compound useful as a raw material for an optical product, especially a plastic lens having a high refractive index is produced by a short reaction proce...
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JPWO2005079845A1 |
The present invention is 5-HT2BAnd 5-HT75-HT with selective binding affinity for the receptor2BAnd 5-HT7The present invention relates to a migraine preventive drug containing a receptor double antagonist as an active ingredient. These mi...
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JP3948184B2 |
To provide a silver halide emulsion having high sensitivity in the visible to ultrared region and less liable to a change of its sensitivity due to a change in exposure conditions and a photographic sensitive material. The silver halide ...
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JP3950046B2 |
The present invention relates to certain resorcinol derivatives and their use as skin lightening agents.
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JP2007517841A |
The invention relates to substituted 1,3-diphenylprop-2-en-1-one derivative compounds, pharmaceutical and/or cosmetic compositions containing same, and the applications thereof in therapeutics and cosmetics. The invention also relates to...
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JP3938319B2 |
To provide a monomer which gives a polymer for optical parts having good transparency, mechanical properties, heat resistance, etc., a low color chromatic aberration (a high Abbe number), a low birefringence, a high melt flowability, and...
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JP2007515510A |
A method of forming a SAM on at least one surface of a substrate by application to said surface of a 2-mono-, or 2,2-disubstituted 1,3-dithiacyclopentane so as to form a SAM prepared therefrom on said surface.
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JP2007126358A |
To provide a compound having excellent VLA-4 inhibitory activity.This phenylalanine derivative is represented by general formula (1) [wherein R1 represents a lower alkyl group, a 3-10C cycloalkyl group, a heterocyclic group, or a 6-10C a...
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JP2007508349A |
The invention relates to substances which specifically inhibit peptidases splitting ala-p-nitroanilide for use in medicine. The invention further relates to the use of at least one such substance or of a pharmaceutical or cosmetic compos...
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JP2007070238A |
To provide a crystalline α-lipoic acid lysine salt of high purity having a uniform composition and a high bulk density, and a manufacturing method thereof.The α-lipoic acid lysine salt is manufactured by a crystallization method that c...
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JP2007042717A |
To provide a compound usable as a p-type organic semiconductor material having the high hole mobility and on/off ratio and allowing film formation by application of a solution or a printing method such as ink-jet printing.It is possible ...
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JP2007001982A |
To provide a method for screening a substance for the ability to exert an influence on the formation of a retinoid X receptor homodimer comprising a step for combining the substance and a solution containing retinoid X receptors and a st...
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JP3863486B2 |
To provide a method for producing a dihydroxycarboxylic ester of formula I as an intermediate for producing R-(+)-α-lipoic acid with a relative amount of complex hydrides in the absence of solvent in a high yield. This method for produc...
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JP3857333B2 |
PURPOSE: To obtain the subject material improved in shelf life of a latent image without adversely affecting the shelf life of emulsions and various photographic properties by forming a photosensitive silver halide emulsion layer contain...
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JP3856830B2 |
PCT No. PCT/GB96/01278 Sec. 371 Date May 12, 1999 Sec. 102(e) Date May 12, 1999 PCT Filed May 30, 1996 PCT Pub. No. WO96/38437 PCT Pub. Date Dec. 5, 1996A process for the preparation of lipolic acid (thioctic acid), or a derivative there...
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JP2006327953A |
To obtain a new S-containing cyclic compound useful as a raw material for optical resins having good heat resistance, high transparency and high refractive index and provide a method for producing the same.The S-containing cyclic compoun...
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JP2006321732A |
To provide a composition for removing abnormal proteins comprising a highly effective abnormal protein-removing component, and to provide an anti-ageing composition contributing to prevention and treatments of diseases caused by abnormal...
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JP2006526571A |
The present invention relates to novel alpha -keto carbonyl calpain inhibitors for the treatment of neurodegenerative diseases and neuromuscular diseases including Duchenne Muscular Dystrophy, Becker Muscular Dystrophy and other muscular...
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JP3847591B2 |
To provide a linker compound capable of simply fixing an oligosaccharide chain to the surface of a support for analyzing protein in one stage using an oligosaccharide of every kind isolated from the natural world and obtained by refining...
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JP3847336B2 |
PCT No. PCT/EP95/02684 Sec. 371 Date Jan. 15, 1997 Sec. 102(e) Date Jan. 15, 1997 PCT Filed Jul. 11, 1995 PCT Pub. No. WO96/03366 PCT Pub. Date Feb. 8, 1996The present invention relates to novel substituted bicyclic 2-mesityl-cyclopentan...
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JP3846815B2 |
To provide a heat developable photographic sensitive material having high Dmax, ultrahigh contrast and satisfactory image quality by incorporating an org. silver salt, silver halide, a reducing agent, a specified hydrazine compd. and oth...
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JP2006524646A |
The invention relates to ammonium salts of alpha-liponic acid of general formula (I): (Lp) (A), formed from alpha-liponic acid (Lp) and amino compounds (A)=of general formula (II) or general formula (III). The invention also relates to a...
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JP2006298903A |
To obtain a medicine to be efficacious in the treatment of T-helper cell type 2 (Th2)-mediated immune diseases such as immunoglobulin E (IgE)-mediated allergic diseases.The medicine composition comprises retinoids with retinoid receptor ...
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JP2006278692A |
To provide an organic field effect transistor in which a channel forming region is composed of an organic semiconductor molecule soluble in a solvent and capable of film-forming by a so-called wet process.The organic field effect transis...
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JP2006265202A |
To provide a new salt which makes it possible to administer a hardly water-soluble α-lipoic acid in the form of an aqueous solution.This method for producing the α-lipoic acid basic amino acid salt comprises dissolving the α-lipoic ac...
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JP3822510B2 |
To reduce a problem of load on the environment by an organic solvent, a halogenated product or the like and to easily and highly efficiently synthesize not only an ether and an acetal but also a thioether and a thioacetal. Same or differ...
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JP2006241040A |
To provide a substituted difluoroacetic acid at a high yield which acid perfectly keeps three dimension of a raw material carboxylic acid derivative, without using any agent having high corrosivity or nasty smell as a reaction agent but ...
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JP3820183B2 |
To provide an optical plastic that solves a fault of a conventional optical plastic, has excellent productivity capable of polymerizing and molding in a short time, good thermal properties and mechanical properties, as well as high refra...
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JP3815691B2 |
PURPOSE: To obtain a new propenoic acid derivative, having antagonistic actions on adenosine A1 and useful as a preventing and a therapeutic agent for renal failure, a diuretic agent, etc. CONSTITUTION: This propenoic acid derivative is ...
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JP3800051B2 |
To obtain a liquid crystalline compound having large absolute value of an anisotropy of permittivity (&verbar Δε&verbar ) and relatively small value of anisotropy of refraction index, a liquid crystal composition containing the compoun...
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JP2006151909A |
To provide a food eliminating and preventing obesity by preventing systemic and/or local excessive accumulation of fats in relation to a composition for inhibiting the fat accumulation in white fat cells.A fat accumulation inhibitor stro...
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JP2006137730A |
To obtain an anti-fatigue agent or a stamina enhancing agent, or to provide a functional food having anti-fatigue action or stamina enhancing action.This invention relates to the anti-fatigue agent or the stamina enhancing agent containi...
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JP2006129826A |
To provide food/drink containing α-lipoic acid by significantly inhibiting α-lipoic acid deterioration through solving such grave drawbacks involved in α-lipoic acid as to emit odor peculiar to sulfur compound or develop turbidity of ...
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JP3778391B2 |
To ensure high efficiency of photodegradation and high sensitivity and to form a superior resist pattern by using a specified compd. generating sulfonic acid. This photosensitive compsn. contains a resin having groups which are decompose...
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JP2006510621A |
The invention relates to a process for purifying lipoic acid, which comprises adding to a solution of lipoic acid at least 0.1 times the amount of an adsorbent, based on the mass of lipoic acid to be purified, and subsequently removing t...
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JP2005533013A |
The present invention relates to multifunctional beta-agonist compounds comprising a reactive oxygen species scavenger group and a nitric oxide donor, and to methods of treating chronic obstructive airway diseases, such as asthma and chr...
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JP2005533013A5 |
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JP2005298337A |
To provide a pinene derivative which is a new intermediate and expressed by formula (1) and a method for producing the same, and a method for producing an aminohydroxycyclohexylpropanoic acid expressed by formula (V) by using the interme...
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JP2005531639A |
The present invention provides compounds of Formula I, compositions and methods that are useful for treating viral infections and associated diseases, particularly HCV infections and associated diseases.
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JP2005531638A |
The present invention provides compounds of Formula I, compositions and methods that are useful for treating viral infections and associated diseases, particularly HCV infections and associated diseases.
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JP3704285B2 |
To obtain an electrode material which makes it possible to form a secondary polymer cell large in capacity and excellent in discharge-cycle characteristics. The aniline-type polymer is obtained by oxidative polymerization of an aniline d...
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JP3704471B2 |
Retinoids with retinoid receptor antagonistic activity, pharmaceutically acceptable salts and pharmaceutically acceptable hydrolyzable esters thereof, have been found efficacious in treating T-helper cell type 2 (Th2)-mediated immune dis...
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JP3704055B2 |
To obtain a new intermediate useful for a method for diastereoselective synthesis for preparing optically active cis-nucleosides, nucleoside analogs and derivatives. This intermediate is represented by the formula (I), wherein, W and X a...
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JP3701699B2 |
PURPOSE: To provide the novel derivative capable of expressing strong adhesivity and durability to noble metals such as gold, silver, Pt and Pd, and useful as dental, medical and industrial adhesives. CONSTITUTION: This derivative is a d...
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JP3688552B2 |
To obtain a new compound exhibiting highly intense affinity for melatonin receptors and selectivity to the subspecies of melatonin-agonistic receptors, and useful as a melatonic analogue. This new compound is a compound of the formula A-...
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JP3688549B2 |
To obtain a new compound which exhibits highly strong affinity with melatonin receptors and/or exhibits good selectivity for any one melatonin- agonizing receptor sub-type. A compound of the formula : A-G1-Cy-G2-Cy-G3-B {A is a group of ...
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JP2005522446A |
The present invention relates to the use of 5-(p-methoxyphenyl)-1,2-dithiole-3-thione or of a pharmaceutical derivative thereof for the preparation of a medicament for preventing lung cancer in a mammalian subject, especially for prevent...
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JP2005167175A |
To provide an organic dopant that is easily handled in the manufacturing process and is capable of fabricating organic semiconductors with high reproducibility.To dope organic semiconductor matrix materials and change the electrical prop...
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JP2005515228A |
The invention relates to a method for producing pure racemic, R- or S-thioctic acid or mixtures thereof by reacting 6,8-disubstituted octanoic acid or their salts or esters with sulfides, sulfur or sulfites.
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