Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 251 - 300 out of 2,518

Document Document Title
WO/2004/098582A2
The present invention pertains to certain ketones and reduced ketones and derivatives thereof which, inter alia, inhibit osteoclast survival, formation, and/or activity; and/or inhibit bone resorption, and more particularly to compounds ...  
WO/2004/094403A1
Salt of thioctic acid with L-carnitine with the formula: A Y (X)x where A is formula (I) where Y is the cation of an alkaline metal, of an alkaline earth metal or is a quaternary ammonium group, X is A or OH-, x is equal to 0 when Y is t...  
WO/2004/092157A1
The invention relates to ammonium salts of &agr -liponic acid of general formula (I): (Lp) (A), formed from &agr -liponic acid (Lp) and amino compounds (A) of general formula (II) or general formula (III). The invention also relates to a...  
WO/2004/089927A1
Methods of inhibiting the cytokine or biological activity of Macrophage Migration Inhibitory Factor (MIF) comprising contacting MIF with a compound of formula (I) are provided. The invention also relates to methods of treating diseases o...  
WO2004050084A3
Multifonctional ACE inhibitor compounds are provided, that combine ACE-inhibiting activity with capability to scavenge superoxide and other reactive oxygen species, and that may further function as nitric oxide donors. The compounds are ...  
WO2003079403A3
The present invention provides biotechnologically useful oligo(ethylene glycol)-terminated 1,2-dithiolane compositions and conjugates of these compositions with biological or non-biological receptor, ligand, sequestering, or reporter moi...  
WO/2004/078908A2
The present invention relates to novel &agr -keto carbonyl calpain inhibitors for the treatment of neurodegenerative diseases and neuromuscular diseases including Duchenne Muscular Dystrophy, Becker Muscular Dystrophy and other muscular ...  
WO/2004/077511A2
The present invention provides novel (meth)acrylic and (meth)acrylamide monomers and polymers produced from those monomers. The monomers of the invention each include only a single vinyl functionality and at least one non-vinyl functiona...  
WO2004060971A3
The present invention relates to sulfide-containing polythiols and their methods of preparation.Sulfide-containing polythiols can have a variety of uses and applications. The sulfide-containing polythiols of the present invention can be ...  
WO/2004/069774A2
There is provided a method of producing novel 13C-labelled estrogen analogues. The method preferably proceeds via an intermediate A or B or which is a mixture of (A) or (B): wherein a 13C atom is located at one or more of positions 1, 2,...  
WO/2004/060971A2
The present invention relates to sulfide-containing polythiols and their methods of preparation.Sulfide-containing polythiols can have a variety of uses and applications. The sulfide-containing polythiols of the present invention can be ...  
WO/2004/060951A1
The present invention relates to a sulfur-containing polyureaurethane and a method of preparing said polyureaurethane. In an embodiment, the sulfur-containing polyureaurethane adapted to have a refractive index of at least 1.57, an Abbe ...  
WO/2004/055000A1
Compounds of formula (I): [where: R1 is a direct bond, oxygen, a group >CH2, sulphur, a group >C=O, a group-(CH2)2- or a group-N-Ra, where Ra is hydrogen or alkyl; R3, R4, R5 and R6 are hydrogen or substituents&agr ; R8, R9, R10 and R11 ...  
WO2004024681A3
The invention relates to compounds having general formula (I), the preparation method thereof and the use of same in radical organic synthesis. The invention also relates to compounds having formula (II), the preparation method thereof a...  
WO/2004/052316A2
Compounds of formula (I), process for making the same, and cosmetic compositions and methods of skin lightening using compounds of formula (I) as skin lightening agents: (I) wherein each A1 and/or A2 independently is = H or COR, CO2R, CO...  
WO/2004/050084A2
Multifonctional ACE inhibitor compounds are provided, that combine ACE-inhibiting activity with capability to scavenge superoxide and other reactive oxygen species, and that may further function as nitric oxide donors. The compounds are ...  
WO/2004/050594A1
The invention relates to a method for producing a compound of general formula (I): R-(A1-Z-)mB-CF2O-A2-(A3)n-R', in which R represents alkyl, in which one or more CH2 groups can be substituted, independently of one another, by O, CF2, CH...  
WO/2004/048362A1
The invention relates to a method for the purification of liponic acid wherein at least O.1 times the amount of an adsorption agent is added to a solution of liponic acid in relation to the mass of liponic acid to be purified and the ads...  
WO2004018481A3
The invention relates to derivatives of gossypol and, more specifically, thioderivatives, such as 1,3-dithiolane and 1,3-dithiane, of gossypol, gossypolone and methyl ethers of gossypol. The invention also relates to the methods of produ...  
WO2003088927A3
The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agent...  
WO/2004/024681A2
The invention relates to compounds having general formula (I), the preparation method thereof and the use of same in radical organic synthesis. The invention also relates to compounds having formula (II), the preparation method thereof a...  
WO2002103340A3
A piezoelectric crystal element and a sensor utilizing the same are presented for use in a sensor device for identifying at least one foreign material from environment. The crystal element comprises at least one crystal resonator in the ...  
WO/2004/022583A1
A linker compound having a structure represented by the following general formula (1): (1) wherein n is an integer of 1 to 6, and wherein X has a structure being a multi-branched structure moiety comprising three or four hydrocarbon chai...  
WO/2004/018481A2
The invention relates to derivatives of gossypol and, more specifically, thioderivatives, such as 1,3-dithiolane and 1,3-dithiane, of gossypol, gossypolone and methyl ethers of gossypol. The invention also relates to the methods of produ...  
WO2003055852A3
The invention relates to compounds of formula (I), wherein Z represents a hydrocarbon with 2 to 28 C atoms, wherein Z can also comprise elements N, O, P, S, Si and halogen as heteroatoms, R<1> and R<2> are identical or different sulfur p...  
WO2002053522A3
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant inventive are ligands for estrogen receptors and as such may be useful for t...  
WO/2004/002944A1
The present invention provides compounds of Formula I, compositions and methods that are useful for treating viral infections and associated diseases, particularly HCV infections and associated diseases.  
WO/2004/002940A1
The present invention provides compounds of Formula I, compositions and methods that are useful for treating viral infections and associated diseases, particularly HCV infections and associated diseases.  
WO/2003/099806A1
A novel creatine salt and the compositions containing same as active principle, such as dietary supplements, dietetic products, nutraceuticals, cosmetic and drugs, are disclosed.  
WO/2003/098347A1
Triarylsulfonium salts of formula I or II are useful as initiators for cationic photopolymerizations: (FI + FII) wherein Ar1 and Ar2 are independently polycyclic aryl, substituted aryl, heteroaryl, substituted heteroaryl, or aryl or hete...  
WO/2003/088961A1
The present invention relates to multifunctional β-agonist compounds comprising a reactive oxygen species scavenger group and a nitric oxide donor, and their use for the treatment of respiratory diseases involving airway obstruction, su...  
WO/2003/088927A2
The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agent...  
WO/2003/086388A1
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for t...  
WO/2003/087073A1
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for t...  
WO/2003/084532A1
This invention comprises administering to a human or animal in need of treatment an effective amount of an antioxidant lipoic acid derivative and/or pharmaceutically acceptable salts, solvates or stereoisomers thereof for the treatment o...  
WO/2003/079403A2
The present invention provides biotechnologically useful oligo(ethylene glycol)-terminated 1,2-dithiolane compositions and conjugates of these compositions with biological or non-biological receptor, ligand, sequestering, or reporter moi...  
WO/2003/074510A1
The invention relates to dithiolane derivatives of the formula (A), and to conjugates from said dithiolane derivatives with organochemical or biological-chemical molecules. The invention further relates to a method for producing said dit...  
WO/2003/072567A1
Compounds of formula (I) [in which: R1 represents a direct bond, an oxygen atom, a group >CH2, a sulphur atom, a group >C=O, a group -(CH2)2- or a group of formula -N-Ra, where Ra is hydrogen or an alkyl; R4, R5, R6 and R7 are each hydro...  
WO2003008404A3
The present invention relates to sulfonium salts, to methods for their preparation and to radiation curable compositions containing them as photoinitiators.  
WO/2003/070714A1
The present invention relates to a method for the synthesis of highly fluorinated compounds and to novel highly fluorinated compounds. In particular, the present invention relates to the synthesis of highly fluorinated acetals and ketals...  
WO/2003/068219A1
The present invention relates to the use of 5-(p-methoxyphenyl)-1,2-dithiole-3-thione or of a pharmaceutical derivative thereof for the preparation of a medicament for preventing lung cancer in a mammalian subject, especially for prevent...  
WO/2003/066578A1
A pinene derivative represented by the general formula (I) or a salt thereof; and a process for producing the derivative or salt or a process for producing from the derivative or salt an optionally active 2-(t-butoxycarbonyl)amino-3-hydr...  
WO/2003/061651A1
The invention provides non-steroidal ligands for the glucocorticoid receptor, methods for making non-steroidal ligands of the glucocorticoid receptor and methods of using non-steroidal ligands and compositions of non-steroidal ligands of...  
WO/2003/059902A1
The invention relates to a method for producing pure racemic R- or S-thioctic acid or the mixtures thereof by transesterification of 6,8-disubstituted octanoic acids, to the salts or esters thereof with sulfides, sulfur and sulfites. In ...  
WO/2003/055852A2
The invention relates to compounds of formula (I), wherein Z represents a hydrocarbon with 2 to 28 C atoms, wherein Z can also comprise elements N, O, P, S, Si and halogen as heteroatoms, R1 and R2 are identical or different sulfur prote...  
WO2003005960A3
Novel bicyclic-cannabinoids and hexahydrocannabinol analogs are presented. These compounds, when administered in a therapeutically effective amount to an individual or animal, results in a sufficiently high level of that compound in the ...  
WO/2003/048102A1
The invention relates to a method for the production of dihydroxycarboxylate esters and a total synthesis for the production of R-(+)-&agr lipoic acid.  
WO/2003/035885A1
The invention relates to a method for the production of (R)- or (S)-8-chloro-6-hydroxy-octanic acid alkyl esters of general formula (R)-II or (S)-II, wherein R is C¿1-4?-alkyl, from 8-chloro-6-oxo-octanic acid alkyl esters of general fo...  
WO/2003/035078A1
A method for improving the safety and efficacy of catalytic antioxidant salen-metal complexes, such as salenMn(III) complexes, for possible clinical applications comprises combining them with a compound that enhances intracellular thiol ...  
WO2001080856A3
The invention concerns the use of anethole-dithiolethione for producing a medicine for preventing drug-induced tendon toxicity.  

Matches 251 - 300 out of 2,518