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Matches 301 - 350 out of 2,519

Document Document Title
WO2002036641A3
Improved Group 3-11 transition metal based catalysts and processes for the polymerization of olefins are described. Some of the ligands are characterized by a preferred substitution pattern which allows for higher productivities of highl...  
WO2002074738A3
The present application describes novel spiro-cyclic beta -amino acid derivatives of formula (I) or pharmaceutically acceptable salt forms thereof, wherein ring B is a 3-13 membered carbocycle or heterocycle, ring C forms a 3-11 membered...  
WO2002091993A3
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for t...  
WO/2003/016265A1
A compound represented by the following formula, which has excellent PPAR agonistic activity: (I) wherein a, b, and c each is 0 to 4&semi R1 to R6 each represents hydrogen, hydroxy, cyano, halogeno, etc.&semi A1 and A2 each represents a ...  
WO/2003/011852A1
The invention relates to novel modifications of the trometamol salt of R-thioctic acid of formula (I), to methods for producing the same, to pharmaceutical preparations containing said modifications, and to the medical application thereof.  
WO/2003/008404A2
The present invention relates to sulfonium salts, to methods for their preparation and to radiation curable compositions containing them as photoinitiators.  
WO2002044163A3
The invention relates to a method for producing R- and S-lipoic acid and R-dihydrolipoic acid comprising the following steps: (a) reaction of the compound of formula (2) with sodium sulphide and sulphur in methanol, whereby Ms represents...  
WO/2003/005960A2
Novel bicyclic-cannabinoids and hexahydrocannabinol analogs are presented. These compounds, when administered in a therapeutically effective amount to an individual or animal, results in a sufficiently high level of that compound in the ...  
WO/2003/002557A1
Asymmetric compounds of formula (I): [in which: R?1¿, R?2¿ and R?3¿ each represents a direct bond, an oxygen atom, a group >CH¿2?, a sulphur atom, a group >C=O or a group (CH¿2?)¿2?-; R?4¿, R?5¿, R?6¿, R?7¿, R?8¿, R?9¿, R?10...  
WO/2002/103340A2
A piezoelectric crystal element and a sensor utilizing the same are presented for use in a sensor device for identifying at least one foreign material from environment. The crystal element comprises at least one crystal resonator in the ...  
WO2002036585A3
Processes for the preparation of 4,5-bisimino-[1,3]dithiolanes and 2,3-bisimino-[1,4]dithianes are described. The processes involve conversion of an oxalamide to a dithiooxalamide, followed by conversion of the dithiooxalamide to either ...  
WO/2002/091993A2
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for t...  
WO/2002/092591A1
Acrylic esters represented by the general formula (I); polymerizable compositions containing the esters; and cured articles and optical elements, produced by polymerizing the compositions; wherein a is an integer of 0 to 4; R¿1? is a si...  
WO/2002/090314A1
Certain known and novel pyruvate derivatives are particularly active in restoring or preserving metabolic integrity in oxidatively competent cells that have been subjected to oxygen deprivation. These pyruvate-derived compounds include, ...  
WO2002010151A3
The invention relates to a method for producing R-lipoic acid and S-lipoic acid comprising a step selected from the following: (a) distillation of dihydrolipoic acid, (b) reaction of (2) or the stereoisomer thereof, wherein Ms represents...  
WO/2002/089578A1
A hydrophobic-solvent solution or dispersion of a dithiol compound such as 4,5-dichloro-1,2-dithiol-3-one or of DBNPA is microencapsulated with a melamine resin wall material. Thus, the antibacterial ingredient is stabilized by being pro...  
WO/2002/081447A1
This invention relates to novel compounds of 3-cyclopentyloxy-4-methoxyphenyl-isothiazolinone derivatives having the activity to inhibit tumor necrosis factor-&agr (TNF-$g(a)) or cyclic AMP phosphodiesterase IV (PDE 4). In more detail, t...  
WO2002064583A3
The invention relates to bis(alkylthio)carbenium salts of formula (I) wherein R<1>, R<2>, R<3> and Y<-> have the cited designations, and a method for the production of the same. The inventive compounds are advantageously suitable as elec...  
WO/2002/074738A2
The present application describes novel spiro-cyclic $g(b)-amino acid derivatives of formula (I) or pharmaceutically acceptable salt forms thereof, wherein ring B is a 3-13 membered carbocycle or heterocycle, ring C forms a 3-11 membered...  
WO2002032377A3
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for t...  
WO/2002/064583A2
The invention relates to bis(alkylthio)carbenium salts of formula (I) wherein R?1¿, R?2¿, R?3¿ and Y?-¿ have the cited designations, and a method for the production of the same. The inventive compounds are advantageously suitable as ...  
WO2002030918A3
Process for the synthesis of R(+) alpha -lipoic acid comprising the following stages: a) Salifying of racemic thioctic acid with R(+) alpha -methylbenzylamine; b) separation by filtration of the crystallized diastereoisomeric salt of R(+...  
WO2002030917A3
Process for the synthesis of racemic thiotic acid comprising the following stages: a) reaction of the alkyl ester of 6,8-di-halo-octanoic acid in an organic solvent with an aqueous solution of alkali disulfide in presence of a compound f...  
WO2001093865A3
The invention relates to the use of -lipoic acid in reduced or oxidised form, or derivatives thereof which have an intact dithiolane structure in the form of enantiomers, or pharmaceutically acceptable salts, amides, esters, thioesters, ...  
WO/2002/053522A2
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant inventive are ligands for estrogen receptors and as such may be useful for t...  
WO/2002/051774A1
The invention relates to a method for producing disubstituted tetrafluoroethylene derivatives of general formula (I), wherein R?1¿ is a linear or branched, cyclic or acyclic, saturated or unsaturated, aromatic or aliphatic hydrocarbon w...  
WO2002024613A3
The present invention relates to certain resorcinol derivatives and their use as skin lightening agents.  
WO/2002/048073A1
The invention relates to a method for producing compounds having at least one -CF¿2?-O bridge per molecule, according to which: a) an acid is added to at least one ketene dithioketal; b) the obtained bis(alkylthio)carbenium salt is reac...  
WO/2002/048081A1
The invention relates to liquid crystalline compounds of formula (I) wherein R?1¿, R?2¿, A?1¿, A?2¿, A?3¿, A?4¿, Z?1¿, Z?2¿, a, b and c have the designations cited in claim 1. The invention also relates to liquid crystalline medi...  
WO/2002/046150A2
Compounds which mimic the chemical and/or biological activity of discodermolide are provided and intermediates useful in their preparation.  
WO/2002/044163A2
The invention relates to a method for producing R- and S-lipoic acid and R-dihydrolipoic acid comprising the following steps: (a) reaction of the compound of formula (2) with sodium sulphide and sulphur in methanol, whereby Ms represents...  
WO/2002/044111A1
A catalytic transfer hydrogenation process is provided. The catalyst employed in the process is a metal hydrocarbyl complex which is coordinated to defined bidentate ligands substituted with at least one group selected from an optionally...  
WO2001068643A3
The invention concerns novel heterocyclic or benzene derivatives comprising a lateral chain derived from lipoic acid, having an activity inhibiting NO-synthase enzymes producing NO nitrogen monoxide and/or are agents enabling regeneratio...  
WO2001083571A3
Catalyst compositions useful for the polymerization or oligomerization of olefins are disclosed. Certain of the catalyst compositions comprise N-pyrrolyl substituted nitrogen donors. Also disclosed are processes for the polymerization or...  
WO/2002/036585A2
Processes for the preparation of 4,5-bisimino-[1,3]dithiolanes and 2,3-bisimino-[1,4]dithianes are described. The processes involve conversion of an oxalamide to a dithiooxalamide, followed by conversion of the dithiooxalamide to either ...  
WO/2002/036533A1
Monomers having electron-withdrawing groups, as represented by the general formula (a), (b) or (c), wherein A?1¿, A?2¿, and A?3¿ are each a ring; R?a¿, R?b¿, R?c¿, and R?u¿ are each independently hydrogen or an organic group; at l...  
WO/2002/036641A2
Improved Group 3-11 transition metal based catalysts and processes for the polymerization of olefins are described. Some of the ligands are characterized by a preferred substitution pattern which allows for higher productivities of highl...  
WO/2002/034740A1
The invention relates to a method for producing cyclic carboxylic orthoester fluorides, comprising the following steps: a) reacting at least one bis(alkylthio)carbenium salt in the presence of at least one base with at least one organic ...  
WO2001085165A3
The invention relates to the use of lipoic acid and C1 donors, especially S-adenosylmethionine and/or 5-methyltetrahydrofolate, for treating disorders of the central nervous system. The invention also relates to agents containing a corre...  
WO/2002/032377A2
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for t...  
WO/2002/030919A1
Process for the synthesis of R(+)$g(a)-lipoic acid comprising the following stages: a) Salifying of racemic 6,8-halo-octanoic acid with S(-)$g(a)-methylbenzylamine; b) separation by filtration of the crystallized diastereoisomeric salt o...  
WO/2002/030918A2
Process for the synthesis of R(+)$g(a)-lipoic acid comprising the following stages: a) Salifying of racemic thioctic acid with R(+)$g(a)-methylbenzylamine; b) separation by filtration of the crystallized diastereoisomeric salt of R(+)$g(...  
WO/2002/030917A2
Process for the synthesis of racemic thiotic acid comprising the following stages: a) reaction of the alkyl ester of 6,8-di-halo-octanoic acid in an organic solvent with an aqueous solution of alkali disulfide in presence of a compound f...  
WO/2002/026909A1
Compositions and methods for using these compositions to produce high yields of thionated compounds are provided.  
WO/2002/024613A2
The present invention relates to certain resorcinol derivatives and their use as skin lightening agents.  
WO/2002/022694A1
Catalyst compositions useful for the polymerization of olefins are disclosed. These compositions comprise a Group 8-10 metal complex comprising a bidentate or variable denticity ligand comprising two nitrogen donor atoms independently su...  
WO/2002/010151A2
The invention relates to a method for producing R-lipoic acid and S-lipoic acid comprising a step selected from the following: (a) distillation of dihydrolipoic acid, (b) reaction of (2) or the stereoisomer thereof, wherein Ms represents...  
WO/2002/010113A1
The invention relates to a method for producing compounds of general formula (I) wherein R?1¿ represents a C¿1?-C¿20? alkyl group, a C¿3?-C¿12? cycloalkylgroup, a C¿7?-C¿12? aralkyl group, or a mono or bicyclic aryl group. A keton...  
WO/2002/002533A1
Medicinal compositions, in particular, GnRH receptor antagonists comprising propane-1,3-dione derivatives represented by the following general formula (1) as the active ingredient; and novel propane-1,3-dione derivatives having a GnRH an...  
WO2001049250A3
Active acne and acneiform scars are treated by topical application of a composition containing lipoic acid and/or a lipoic acid derivative such as dihydrolipoic acid, a lipoic or dihydrolipoic acid ester, a lipoic or dihydrolipoic acid a...  

Matches 301 - 350 out of 2,519