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Matches 1 - 50 out of 61,166

Document Document Title
WO/2018/130443A1
The invention relates to novel compounds of formula (I), wherein X, R1, R2, R3 and n have the meanings indicated in the description, to the use thereof as acaricides and/or insecticides for controlling animal pests, and to methods and in...  
WO/2018/131557A1
Provided are: a dicyano N-heterocyclic compound represented by formula (I) (in the formula, R3 represents an electron-donating group, and n represents the number of repetitions of the content in brackets and is 0 or 1), the compound havi...  
WO/2018/130838A1
The present invention relates to 2-thiobenzimidazoles of formula (I) which are of use as fungicides.  
WO/2018/131866A1
The present disclosure relates to an organic electroluminescent device. The organic electroluminescent device of the present disclosure can exhibit low driving voltage, high efficiency and/or long lifespan by comprising a specific combin...  
WO/2018/130184A1
The present invention relates to a 1,2,4-triazine-3-amine derivative, a preparation therefor, and use thereof in medicine. Specifically, the present invention relates to a 1,2,4-triazine-3-amine derivative as represented by general formu...  
WO/2018/131690A1
[Problem] To provide a novel agrochemical, especially a novel herbicide. [Solution] A ketone or oxime compound represented by formula (1), and a herbicide which contains this compound. (In the formula, B represents B-1 or B-2; Q represen...  
WO/2018/132279A1
The invention relates generally to compounds of formula (I) that modulate the activity of TGFβR-l and TGFβR-2, pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysre...  
WO/2018/130625A1
The present invention relates to novel substituted benzene disulfonamides, as well as pharmaceutical compositions containing at least one of these substituted benzene disulfonamides together with at least one pharmaceutically acceptable ...  
WO/2018/132636A1
The present invention provides a compound having the structure: (Formula I), and a method of inhibiting Glycogen synthase kinase-3 β (GSK-3β) in a subject comprising administering to the subject said compound, so as to thereby inhibit ...  
WO/2018/130227A1
Disclosed are an aromatic ring-containing compound, a preparation method therefor, a pharmaceutical composition, and use. The present invention provides an aromatic ring-containing compound as represented by formula (1), a pharmaceutical...  
WO/2018/127801A1
Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infect...  
WO/2018/129557A1
The present disclosure is directed to compounds (Ι') and to their use in methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic k...  
WO/2018/129556A1
The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-sta...  
WO/2018/127800A1
Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infect...  
WO/2018/125961A1
The present invention is related to a pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent and a compound represented by the following structural formula: The present invention is also related a method o...  
WO/2018/124000A1
The present invention addresses the problem of providing a compound that, when used in the treatment of cystic fibrosis, which is caused by a mutation of a cystic fibrosis transmembrane conductance regulator (CFTR), which is a kind of ch...  
WO/2018/120978A1
The present invention relates to an organic electroluminescence device containing a 1,2,4-triazine based bipolar main material, comprising: a cathode, an anode, and an organic layer; the original layer is one or more of a hole transport ...  
WO/2018/123918A1
Provided is a compound or a salt thereof, represented by the formula shown, which has a RORγt inhibitory effect and is useful as a preventive or therapeutic agent for autoimmune diseases, allergies, and the like.  
WO/2018/121434A1
Disclosed is an aryl hydrocarbon receptor modulator as represented by formula (I) and a pharmaceutically acceptable salt. R' is H, CN, CH2(OH)R0, CmH2m+1, CnH2n-1, CnH2n-3, formula (A), formula (B), or formula (C); two Ra are independent...  
WO/2018/124001A1
The present invention pertains to novel, exceptional low-molecular compounds that specifically antagonize the BMP signaling pathway, and because these compounds can be used to modulate cell growth, differentiation, proliferation, and apo...  
WO/2018/122775A1
The application is directed to compounds of formula (I): and their salts and solvates, wherein R1, R2, R3, A1, A2, A3, and n are as set forth in the specification, as well as to a method for their preparation, pharmaceutical compositions...  
WO/2018/122746A1
The application is directed to compounds of formula (I) : (I), and formula (IA): (IA) and their salts and solvates, wherein R1, R2, R3, R4, R5, n, A1, A2, A3, and Y are as set forth in the specification, as well as to a method for their ...  
WO/2018/121551A1
The present invention relates to an azabicyclo-substituted triazole derivative, a preparation method thereof, and an application of the same in medicine. In particular, the present invention relates to a novel azabicyclo-substituted tria...  
WO/2018/124088A1
Provided are novel pest control agents, in particular, a bactericide and a nematicide. An alkylphenyl-substituted amide compound represented by formula (I) [wherein: G1 stands for a structure represented by G1-2, G1-3, G1-4, etc.; X1 sta...  
WO/2018/120977A1
A spiro-[fluorine-9,2'-imidazole] based bipolar main material, a synthesis method therefor, and an application thereof, relating to the field of organic electronic materials. The bipolar main material has a compound having the structure ...  
WO/2018/120979A1
The present application relates to a 1,2,4-triazine based bipolar main material and an application thereof. The 1,2,4-triazine based bipolar main material has a compound having the structure of formula (I), wherein R1-R6 represent substi...  
WO/2018/124179A1
The present invention provides a compound represented by general formula (I) (in the formula, X is as described in the description and claims) or a pharmacologically acceptable salt thereof, and provides a pharmaceutical composition cont...  
WO/2018/125820A1
The disclosure relates to efficient and economical synthetic chemical processes for the preparation of pesticidal thioethers. Further, the disclosure relates to certain novel compounds useful in the preparation of pesticidal thioethers.  
WO/2018/124236A1
Provided is a medicinal composition to be used for treating an intractable heart tissue fibrosis disease accompanying chronic heart failure. The medicinal composition, which is to be used for treating an intractable heart tissue fibrosis...  
WO/2018/125818A1
This application relates to efficient and economical synthetic chemical processes for the preparation of pesticidal thioethers. Further, the present application relates to certain novel compounds useful in the preparation of pesticidal t...  
WO/2018/125983A1
The present invention is related to a compound represented by the following structural formula: The present invention is also related a method of treating a subject with a disease which can be ameliorated by inhibition of aminocarboxymuc...  
WO/2018/121550A1
The present invention relates to a quinazoline compound and a preparation method, an application, and a pharmaceutical compostion thereof. The present quinazoline compound is represented by the formula (I), is a phosphatidylinositol 3-ki...  
WO/2018/122559A1
The present invention relates to compounds which are of use in the field of agriculture as herbicides. The invention also relates to methods of using said compounds and compositions comprising said compounds.  
WO/2018/122232A1
Disclosed are sulfonamide compounds with GPR17 modulating properties, which are useful for treating or preventing a variety of CNS and other diseases, in particular for preventing and treating myelinating diseases or disorders.  
WO/2018/114910A1
The invention provides amidine compounds of Formula (I) for the treatment of neurodegenerative or cognitive diseases, including Alzheimer's Disease.  
WO/2018/114648A1
The present invention relates to solid forms of the insecticide of formula (I): (I) compositions comprising the solid forms and methods of their use as insecticides.  
WO/2018/118109A1
Disclosed is a composition which is BA-1049 (R).  
WO/2018/119208A1
The present disclosure provides certain angular tricyclic compounds that are histone methyltransi erases G9a and/or GLP inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of G9a and/or GLP such as c...  
WO/2018/115218A1
The present invention provides compounds which are selective allosteric inhibitors of T790M and C797S containing EGFR mutants, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substan...  
WO/2018/119286A1
Disclosed are compounds of Formula (I), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders...  
WO/2018/116260A1
The invention relates to a pharmaceutical composition for treating tuberculosis, containing an active ingredient and at least one pharmaceutically acceptable excipient, wherein the active ingredient contains a compound of formula I.  
WO/2018/119221A1
Disclosed are compounds of Formula (I), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders...  
WO/2018/119448A1
The present disclosure relates to bifunctional compounds, which find utility as modulators of Rapidly Accelerated Fibrosarcoma (RAF, such as c-RAF, A-RAF and/or B-RAF; the target protein). In particular, the present disclosure is directe...  
WO/2018/118848A1
The present disclosure generally relates to compounds useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical composit...  
WO/2018/113900A1
Compounds of formula (I) wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides and can be pre...  
WO/2018/114783A1
The present invention relates to tetrazole containing compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufa...  
WO/2018/119036A1
Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT1. Such compounds are represented by Formula (I) wherein R1, R2, R3, R4, R5, R6, ...  
WO/2018/118735A1
The present invention is directed to 6,6-fused heteroarylpiperidine ether compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described he...  
WO/2018/113694A1
The present invention relates to a condensed ring group azacyclobutyl triazole derivative, a preparation method therefor and use thereof in medicine. In particular, the present invention relates to a novel condensed ring group azacyclobu...  
WO/2018/119357A1
The present disclosure relates to bifunctional compounds, which find utility as modulators of enhancer of zeste homolog 2 (target protein). In particular, the present disclosure is directed to bifunctional compounds, which contain on one...  

Matches 1 - 50 out of 61,166