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Matches 551 - 600 out of 6,894

Document Document Title
WO/2013/041652A1
The invention relates to compounds of formula (I), wherein m, n, R 1, T 0 and T 1 have the meaning as cited in the description and the claims. Said compounds are useful as inhibitors of mTOR for the treatment or prophylaxis of mTOR relat...  
WO/2013/042124A1
Compound of formula X wherein P1 is a fused-ring system comprising one 6-membered and two 5- membered rings; v indicates an S or R configuration; or individual isomers or pharmaceutically acceptable salts thereof, or mixtures thereof, in...  
WO/2012/052491A3
The present invention relates to fungicidal 1-(heterocyclic carbonyl)-2-substituted pyrrolidines and their thiocarbonyl derivatives, their process of preparation and intermediate compounds for their preparation, their use as fungicides, ...  
WO/2013/037896A1
The present invention relates to disubstituted 5-fluoro-pyrimidines of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of ...  
WO/2013/037753A1
The present invention relates to novel non-steroidal brassinosteroid mimetic derivatives, to processes and intermediates for preparing them, to plant growth regulator compositions comprising them and to methods of using them for controll...  
WO/2013/036671A1
The present invention provides compounds of formula I: or a pharmaceutically acceptable salt thereof, wherein L and Ring A are as defined and described herein, compositions thereof, and methods of using the same.  
WO/2013/033901A1
The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, ...  
WO/2013/033900A1
The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, ...  
WO/2013/032278A1
The present invention relates to a novel compound and an organic electroluminescent device containing the same. Since the compounds according to the present invention have high efficiency in transporting electrons, crystallization could ...  
WO/2013/032297A1
The present invention relates to novel organic electroluminescence compounds and an organic electroluminescence device containing the same. The compounds according to the present invention have high luminous efficiency and long operation...  
WO/2013/032960A2
Described herein are compounds, pharmaceutical compositions and methods for inhibiting the expression of a vitamin D receptor target gene, inhibiting interactions between the vitamin D receptor and at least one vitamin D receptor coactiv...  
WO/2013/029479A1
Disclosed in the present invention is a mycophenolic acid derivative shown by the following general formula (V) and the pharmaceutically acceptable salts thereof, wherein L1 is -O-R2, -QCOOR2 or -QCONR2R3, Q is C1~C10. Alkylidene or C1~C...  
WO/2013/026724A1
The present invention relates to compounds of formula (IA) wherein QA is QA1 or QA2 P is P1, heterocyclyl or heterocyclyl substituted by one to five Z; and wherein A1, A2, A3, A4, G1, Z, R1, R2, R3 and R4 are as defined in claim 1; or a ...  
WO/2013/027000A1
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1 and R2 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them an...  
WO/2013/027001A1
The present invention provides compounds of formula (1) and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, m, n, p, q, Q1, Q2, Q3, Q4, Q5, Q6,...  
WO/2012/173842A3
The present invention relates to a process for the purification of para-methallylpyrocatechol and to the preparation of flavor and fragrance compounds from para-methallylpyrocatechol.  
WO/2013/028045A2
The present invention relates to an epoxy compound having an alkoxysilyl group, a method for preparing same, a composition and cured material comprising same, and usage thereof. A composite comprising the epoxy compound exhibits superior...  
WO/2013/026726A1
The present invention provides compounds of formula I wherein Q is Q1 or Q2; A1, A2, A3 and A4 are independently of each other C-H, C-R7, or nitrogen; R1 is C1-C8haloalkyl; R2 is aryl or aryl substituted by one to five R11, or heteroaryl...  
WO/2012/149157A3
Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for t...  
WO/2013/025074A2
The present invention relates to an anticancer or antioxidant composition containing, as an active ingredient, a Quamoclit pennata extract or a novel compound derived from Quamoclit pennata. The composition according to the present inven...  
WO/2013/024968A1
The present invention relates to a novel compound isolated from quamoclit, and to a composition containing the compound as an active ingredient, and more particularly, to a novel compound isolated from quamoclit, and to a composition for...  
WO/2013/020930A1
The present invention relates to aminochromane, aminothiochromane and 1,2,3,4-tetrahydroquinoline derivatives of the formula (I), or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprisin...  
WO/2013/020370A1
Provided is a PIM kinase inhibitor as represented by formula (I), wherein E, J, Q, X, Y, Z, and m are defined in claim 1. The PIM kinase inhibitor of the present invention is used for preparing medicines for treating and preventing cance...  
WO/2013/018053A1
The present invention relates to a novel process of synthesis of epoxides, 6-fluoro-2- (oxiran-2-yl) chroman (Figure 1), intermediates for the synthesis of nebivolol, depicted in Scheme (1), enabling to obtain the above- mentioned epoxid...  
WO/2013/019662A1
Provided herein are glycosidic aryl naphthalide lignans compounds, such as justiprocumin A isolated from the plant Justicia gendarussa Burm.f. (Acanthaceae), which are effective in the treatment of AIDS and HIV infections.  
WO/2013/016120A1
Compounds that include a pederin, psymberin or pederin/psymberin chimera scaffold. The pederin scaffold includes a substituent at the C10 and/or C13 position that may include a linker that may be conjugated to a targeting moiety. The psy...  
WO/2013/012298A1
The present invention relates to a novel organic luminescent compound and an organic electroluminescent device containing the same. The compounds according to the present invention have high luminous efficiency and long operation lifetim...  
WO/2013/012829A1
The present invention provides compounds of Formula (I) or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are agonists, partial agonists and modulators o...  
WO/2012/092484A3
This invention is directed to novel compounds of formula (I) having the structure (I) wherein U, V, W, Z, R 1, X1, X2, and Y are defined herein. The compounds of formula (I) and pharmaceutical compositions containing these compounds are ...  
WO/2012/151142A3
Compounds having chemiluminescent flash and glow properties. Also disclosed are methods using the compounds to generate light, detect and/or quantify enzymes, antigens, and/or nucleic acids. Also disclosed are kits relating to these comp...  
WO/2013/001352A2
The present invention provides a method for preparing Cleistanthin A, a diphyllin glycoside, derivatives thereof and intermediates thereto. In particular the present invention provides in one of the aspect a method for synthesis of compo...  
WO/2012/089349A3
The present invention relates to novel polyketide compounds and to enzymes and production organisms for obtaining such novel polyketide compounds. Polyketides of the present invention include non-natural, chemically active extender units...  
WO/2012/176918A1
Specifically provided is a chromene compound represented by formula (1), which has a short fading half-life even at low temperatures in a common polymer solid matrix. (In formula (1), R1 represents a hydroxyl group or the like; each of R...  
WO/2012/128530A3
The present invention relates to novel 2-methyl-2-alkyl-6-amido-2H-benzopyran derivatives having an excellent NF-ĸB target gene expression inhibitory activity and pharmaceutically acceptable salts thereof, a preparation method of the co...  
WO/2012/171175A1
The present invention relates to the use of Formula (I) where Y represents * denoting the point at which the moiety bonds to the bicyclic ring, in any one of its stereoisomenc forms or mixtures thereof to confer, enhance, impart and/or m...  
WO/2012/173842A2
The present invention relates to a process for the purification of para-methallylpyrocatechol and to the preparation of flavor and fragrance compounds from para-methallylpyrocatechol.  
WO/2012/170554A1
The invention provides molecular entities that bind with high affinity to PPARG (PPARƴ), inhibit kinase-mediated, e.g., cdk5-mediated, phosphorylation of PPARG, but do not exert an agonistic effect on PPARG. Compounds of the invention c...  
WO/2012/162115A2
The present invention is directed to a novel process for the preparation of compounds having inhibitory activity against sodium-dependent glucose transporter (SGLT) being present in the intestine or kidney.  
WO/2012/161877A1
Compounds of the formula (I) in which R, R1 and X have the meanings indicated in Claim 1, are inhibitors of TBK1 and IKKε and can be employed, inter alia, for the treatment of cancer and inflammatory diseases  
WO/2012/162113A1
The present invention is directed to a novel process for the preparation of compounds having inhibitory activity against sodium-dependent glucose transporter (SGLT) being present in the intestine or kidney.  
WO/2012/157832A1
The present invention relates to a photocurable isosorbide derivative, a manufacturing method thereof, and a photocurable composition including the same, more specifically to an environmentally friendly biomass-derived photocurable compo...  
WO/2012/150826A1
An organic electroluminescent compound of formula 1 and an organic electroluminescent device comprising the same is disclosed. The organic luminescent compound provides an organic electroluminescent device which has high luminous efficie...  
WO/2012/151142A2
Compounds having chemiluminescent flash and glow properties. Also disclosed are methods using the compounds to generate light, detect and/or quantify enzymes, antigens, and/or nucleic acids. Also disclosed are kits relating to these comp...  
WO/2012/149157A2
Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for t...  
WO/2011/116177A8
A process for preparing a divinylarene dioxide including reacting (a) at least one divinylarene; (b) at least one oxidant, wherein the at least one oxidant includes a peroxomonosulfate triple salt oxidant, and wherein the at least one ox...  
WO/2012/143340A1
The present invention relates to ethynyl derivatives of formula (I), wherein, Y is N or C-R3;and R3 is hydrogen, methyl, halogen or nitrile; R1 is phenyl or pyridinyl, which are optionally substituted by halogen, lower alkyl or lower alk...  
WO/2012/140642A1
Biologically active compounds, which are useful for treating a sexual disorder, are provided herein. Further provided are pharmaceutical compositions formulated for transdermal composition, which comprise a biologically active compound u...  
WO/2012/142513A1
The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutic...  
WO/2012/140596A1
The present invention provides a compound of formula I; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a ph...  
WO/2012/140243A1
The present invention relates to compounds, their use in the treatment or the prevention of viral disorders, including HIV.  

Matches 551 - 600 out of 6,894