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Patent Searching and Data


Matches 701 - 750 out of 7,152

Document Document Title
WO/2012/138776A1
The present invention relates to compounds of formula I or II, or pharmaceutically acceptable salts thereof, that interact with glucokinase regulatory protein. In addition, the present invention relates to methods of treating type 2 diab...  
WO/2012/137181A1
The present invention relates to compounds of formula (1) as claimed in claim 1, their use in the treatment or the prevention of viral disorders, including HIV. (Formula I)  
WO/2012/128530A2
The present invention relates to novel 2-methyl-2-alkyl-6-amido-2H-benzopyran derivatives having an excellent NF-ĸB target gene expression inhibitory activity and pharmaceutically acceptable salts thereof, a preparation method of the co...  
WO/2012/120018A1
The process of the invention relates to a compound of formula (I), the process for preparing same from reduced sugar and aldehyde and the uses of these compounds in particular as surfactant.  
WO/2012/065116A3
Disclosed herein is a polyhydroxy ketal adduct obtained by forming an ester between of a hydrocarbon polyol and at least 1.5 equivalents of a ketocarboxy to produce an intermediate ketocarboxylic ester. The intermediate polyketocarboxyli...  
WO/2012/110470A1
The present invention is concerned with novel dual modulators of the 5-HT2A and D3 receptors of formula (I) wherein n, Y, R1, R2, R3, and R4 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. Furthe...  
WO/2012/088266A3
The present invention relates to substituted imidazopyridazines and substituted benzimidazoles, as well as pharmaceutical compositions comprising the same, which are FGFR3 inhibitors useful in the treatment of cancer and other diseases.  
WO/2012/101043A1
The present invention relates to pyrazole compounds of formula (1a) or (1b) and pharmaceutically acceptable salts thereof, wherein Ra, Rb, Rc, Rd, Y1, y2, y3, y4, y5, Z, R1, R2, n and R3 have one of the meanings as indicated in the speci...  
WO/2012/102357A1
The purpose of the present invention is to provide a compound having a potent and sustained activity of decreasing an intraocular pressure and having no adverse side effect on eyes. A compound represented by general formula (I) (wherein ...  
WO/2012/032534A3
The present invention relates to compounds of formula XXII and their synthesis from furanose derivatives as shown hereunder. Compounds of formula XXII are of use in the synthesis of statins.  
WO/2012/074675A3
Grafted triglycerides comprising an acrylated triglyceride grafted with a fatty acid residue containing 4 to 28 carbon atoms. Also described are methods for making a grafted triglyceride and for curing a material selected from vinyl este...  
WO/2012/098217A1
The present invention relates to compounds of general formula (I), wherein the groups R1, LP, LQ, X1, X2, X3, A, n and m are as defined in the application, which have valuable pharmacological properties, and in particular bind to the GPR...  
WO/2012/061012A3
Compounds of Formula I are described, along with methods of using such compounds for the treatment of cancer and pharmaceutical formulations thereof.  
WO/2012/095858A1
The present invention is directed to a process for the preparation of l,3:2,4-bis (4- methylbenzylidene) sorbitol (MDBS) and 1,3:2,4-bis (4-dimethylbenzylidene) sorbitol (DMDBS) by dehydrocondensating an aldehyde and an alditol using a h...  
WO/2012/065114A3
Disclosed herein is a polyketal adduct obtained by forming an ester between a hydrocarbon polyol and a ketocarboxylic acid to produce an intermediate polyketocarboxylic ester. The intermediate polyketocarboxylic ester can be purified via...  
WO/2012/095857A1
This invention is directed to a process for preparation of acetal derivatives, 1,3:2,4-bis (3,4-dimethylbenzylidene) sorbitol (DMDBS) and 1,3:2,4-bis (4-methylbenzylidene) sorbitol (MDBS) by carrying out a dehydrocondensation reaction by...  
WO/2012/070015A9
The present invention relates to compounds which are inhibitors of the activity of Complex III of the mitochondrial electron transport chain and pharmaceutical compositions comprising said compounds alone or in combination with other act...  
WO/2012/097270A1
The present application is directed to solid forms of compounds of formula (I): and pharmaceutically acceptable salts thereof, that inhibit bacterial gyrase and/or Topo IV and pharmaceutical compositions comprising said compounds and sal...  
WO/2012/092484A2
This invention is directed to novel compounds of formula (I) having the structure (I) wherein U, V, W, Z, R 1, X1, X2, and Y are defined herein. The compounds of formula (I) and pharmaceutical compositions containing these compounds are ...  
WO/2012/089349A2
The present invention relates to novel polyketide compounds and to enzymes and production organisms for obtaining such novel polyketide compounds. Polyketides of the present invention include non-natural, chemically active extender units...  
WO/2012/090220A1
The present invention relates to compounds of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use ...  
WO/2012/087007A1
Provided are novel organic electroluminescent compounds and organic electroluminescent devices using the same. Since the organic electroluminescent compound exhibits good luminous efficiency and excellent life property, it may be used to...  
WO/2012/080476A1
The present invention relates to compounds of general formula (I), wherein the groups R1, LP, LQ, X1, X2, X3, Ar and n are as defined in the application, which have valuable pharmacological properties, and in particular bind to the GPR11...  
WO/2012/082513A1
The present invention relates to lactone compounds represented by following Formulas I and II, and methods of making such lactone compounds. Formula (I): and formula (II). The present invention also relates to methods of making other mat...  
WO/2012/079203A1
Disclosed are puerarin hydrates, preparation methods and uses thereof, which belong to the field of pharmaceutical chemistry. Specifically, the formula of puerarin hydrates is C21H20O9·nH2O, wherein n is selected from the value of 0.8-1...  
WO/2012/082506A1
Described herein are compounds generally comprising an indeno[2',3':3,4]naptho[1,2-b] pyran structure. Such compounds may be useful for their photochromic properties, and be used in certain photochromic compositions. Such compositions ma...  
WO/2012/082633A1
The present invention relates to novel bis-sulfonamide derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of chemokine receptors.  
WO/2012/082566A1
The present invention relates to novel sulfur derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of chemokine receptors.  
WO/2012/082560A1
The present invention relates to methods of making fused ring compounds, such as indeno-fused naphthols, and fused ring indenopyran compounds, such as indeno-fused naphthopyrans, that each employ an unsaturated compound represented by th...  
WO/2012/078545A1
The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected w...  
WO/2012/033631A3
Embodiments of the invention relate to compounds and methods for controlling algal growth, for example, in bodies of water or surfaces exposed to algae. Provided are compounds having algicidal activities and methods of use of these compo...  
WO/2012/072691A1
The present invention relates to compounds defined by formula (I) wherein the variables R1, R2, R3, m, and n are defined as in claim 1, possessing valuable pharmacological activity. Particularly, the compounds are activators of the recep...  
WO/2012/074675A2
Grafted triglycerides comprising an acrylated triglyceride grafted with a fatty acid residue containing 4 to 28 carbon atoms. Also described are methods for making a grafted triglyceride and for curing a material selected from vinyl este...  
WO/2012/070437A1
[Problem] To provide a practical production method by which an optically active fluorine-containing oxeten, which can be an important intermediate for pharmaceuticals and agrochemicals, is able to be stably isolated. [Solution] This meth...  
WO/2012/069601A1
Compounds of formula I (I) wherein the other substituents R1, R2, R3, R4, R5 and R6 are as defined in claim 1, and their use as microbicides.  
WO/2012/070015A1
The present invention relates to compounds which are inhibitors of the activity of Complex III of the mitochondrial electron transport chain and pharmaceutical compositions comprising said compounds alone or in combination with other act...  
WO/2012/067425A1
Provided are a novel compound for an organic electronic material and an organic electroluminescent device using the same. The compound for an organic electronic material according to the present invention has high electron transport effi...  
WO/2012/067965A1
Disclosed are compounds of formula (1c) which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed. Disclosed are compounds which inhibit the activity of RO...  
WO/2012/065904A2
The present invention relates to cyanoenamine derivatives, their process of preparation, intermediate compounds, their use as fungicide active agents, particularly in the form of fungicide compositions, and methods for the control of phy...  
WO/2012/065114A2
Disclosed herein is a polyketal adduct obtained by forming an ester between a hydrocarbon polyol and a ketocarboxylic acid to produce an intermediate polyketocarboxylic ester. The intermediate polyketocarboxylic ester can be purified via...  
WO/2012/064559A1
Compounds of Formula (IA) and Formula (IB) are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorder...  
WO/2012/065116A2
Disclosed herein is a polyhydroxy ketal adduct obtained by forming an ester between of a hydrocarbon polyol and at least 1.5 equivalents of a ketocarboxy to produce an intermediate ketocarboxylic ester. The intermediate polyketocarboxyli...  
WO/2012/061012A2
Compounds of Formula I are described, along with methods of using such compounds for the treatment of cancer and pharmaceutical formulations thereof.  
WO/2012/019428A8
Benzohydrol derivatives of formula (I), a preparation method, pharmaceutical compositions and pharmaceutical use thereof are disclosed in the invention. The derivatives can be used as rennin inhibitors to prepare the drugs for the treatm...  
WO/2012/020966A3
The present invention relates to a theanine derivative which selectively inhibits Propionibacterium acnes in the skin, a preparation method thereof, and a use thereof for alleviating acne.  
WO/2012/055942A1
Compounds are disclosed which modulate the α7 nicotinic acetyl choline receptor (nAChR), having the formula (I) wherein the variables are as specified in the description and claims.  
WO/2012/054315A1
The present invention provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof. Also, the present invention provides a pharmaceutical composition comprising a compound of Formula (I) or a pharmaceutically accepta...  
WO/2012/051666A1
An organic electroluminescent device comprising: a pair of electrodes comprising an anode and a cathode, and one or more layers arranged between the anode and the cathode; wherein at least one of the one or more layers is a light emittin...  
WO/2012/052491A2
The present invention relates to fungicidal 1-(heterocyclic carbonyl)-2-substituted pyrrolidines and their thiocarbonyl derivatives, their process of preparation and intermediate compounds for their preparation, their use as fungicides, ...  
WO/2012/049190A1
The present invention relates to compounds of the formula I wherein A, R1 to R7 are defined in the description, and to pharmaceutically acceptable salts thereof, their manufacture, pharmaceutical compositions containing them and their us...  

Matches 701 - 750 out of 7,152