Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 701 - 750 out of 6,886

Document Document Title
WO/2011/100380A1
Provided are 4'-arylmethoxy isoindoline compounds, and pharmaceutically acceptable salts, solvates, clathrates, stereoisomers, and prodrugs thereof. Methods of use, and pharmaceutical compositions of these compounds are disclosed. The co...  
WO/2011/094890A1
Provided herein are non-peptide GLP-1 receptor modulator compounds, for example, of Formula (I), pharmaceutical compositions comprising such compounds, and processes of preparation thereof. Also provided are methods of their use for the ...  
WO/2011/095050A1
Disclosed are C-glycoside sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors containing saturated 6-member rings shown as following general formula I, preparation methods, compositions containing such compounds and uses thereof ...  
WO/2011/095434A1
The present invention relates to a compound of general formula (I) wherein X is -O- or -CH2-; X' is -O- or -CH2-; with the proviso that one of X or X' is always -O- and the other is -CH2-.It has been found that the compounds of general f...  
WO/2011/085886A1
The present invention relates to compounds of formula (I) or to a pharmaceutically active salt thereof. It has been found that the present compounds are high potential NK-3 receptor antagonists for the treatment of depression, pain, psyc...  
WO/2011/084985A1
The present invention relates to compounds of formula I and pharmaceutically acceptable salts thereof, wherein R1 to R3, A, B, X, and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these com...  
WO/2011/033265A8
The invention relates to a series of compounds with particular activity as inhibitors of the serine-threonine kinase AKT. Also provided are pharmaceutical compositions comprising same as well as methods for treating cancer.  
WO/2011/080264A1
New tertiary 8-hydroxyquinoiine-7-carboxamide derivatives of general formula (I) and pharmaceutically acceptable salts thereof are disclosed. These compounds are useful as antifungal agents. Specifically, these compounds were tested agai...  
WO/2011/080445A1
The invention relates to (heterocycle/tetrahydropyridine)-(piperazinyl)-1-alcanone and (heterocycle/dihydropyrrolidine)-(piperazinyl)-1-alcanone derivatives of the general formula (I), where A, W, n, and R2 are as defined in claim 1. The...  
WO/2011/080265A1
The present invention provides secondary 8-hydroxyquinoiine-7-carboxamide derivatives of general formula (I) and pharmaceutically acceptable salts thereof. These compounds are useful as antifungal agents. Specifically, these compounds we...  
WO/2011/080266A1
The present invention provides new secondary 8-hydroxyquinoline-7-carboxamide derivatives of general formula (I) and pharmaceutically acceptable salts thereof. These compounds are useful as antifungal agents. Specifically, these compound...  
WO/2011/079091A1
Provided are (methylsulfonyl)ethyl benzene isoindoline compounds, and pharmaceutically acceptable salts, solvates, or stereoisomers thereof. Methods of use and pharmaceutical compositions of these compounds are also disclosed.  
WO/2011/079034A1
The present invention relates to novel compounds of formulae (I) and (II) and pharmaceutically acceptable salts thereof that are useful in the treatment and/or prevention of human and animal bacterial infections and associated diseases a...  
WO/2011/048148A3
This invention relates to compounds represented by formula (I) wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes...  
WO/2011/073376A1
The present invention is directed to novel compounds of formula (I) and their use in treating and/or preventing metabolic diseases.  
WO/2011/073269A1
Compounds of the formula (I) or pharmaceutically acceptable salts thereof, wherein m, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases assoc...  
WO/2011/073277A1
Compounds of the formula (I), or pharmaceutically acceptable salts thereof, wherein m, n, p, X, R1, R2, R3, R4 R5 and R6 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of d...  
WO/2011/075607A1
The embodiments provide compounds of the general Formulae I, II, III, IV, or V as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including me...  
WO/2011/075634A1
The present invention is directed to novel bicyclic derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by DPP-1.  
WO/2011/073845A1
The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections. Formula (I).  
WO/2011/022679A3
Furanopyridine cannabinoid analog compounds of the formula I are disclosed. The compounds are useful to modify the activity of CB 1 and CB2 receptors and treat conditions mediated by these receptors.  
WO/2011/021726A3
The present invention provides a novel diazepine compound that blocks the IKur current or the Kv1.5 channel potently and more selectively than other K+ channels. The present invention relates to a diazepine compound represented by Genera...  
WO/2011/011721A9  
WO/2011/064249A1
The invention belongs to the field of organic chemistry and relates to a new synthesis of acetoxyacetaldehyde. Comprising the steps of providing monoacetyl ethylene glycol and converting it by oxidation using an N-oxyl compound in the pr...  
WO/2010/111634A3
The invention relates to compounds having the formula: wherein the variables are as defined herein. The invention further relates to methods of making and using these compounds, intermediates which can be used to make the compounds, and ...  
WO/2011/058193A1
The present invention relates to compounds of formula (I) compositions, in particular pharmaceutical compositions, and medicaments comprising at least one compound of formula (I). The invention also relates to the use of such a compound ...  
WO/2011/056652A1
Presently provided are IDO inhibitors of general formulae (VII), (VIII) as shown below and pharmaceutical compositions thereof, useful for modulating an activity of indoleamine 2,3-dioxygenase; treating indoleamine 2,3-dioxygenase (IDO) ...  
WO/2011/051380A1
The present invention relates to a polyketide molecule of the following formula (I): or a pharmaceutically acceptable salt thereof, where R1 is a hydrogen atom or a (C1-C7) group, as well as the method of preparation and use thereof, in ...  
WO/2011/048148A2
This invention relates to compounds represented by formula (I) wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes...  
WO/2011/009084A3
Compounds represented by formula (I) or pharmaceutically acceptable salts and solvates thereof, wherein A, B, B', X, Y, R1, R1 ', R2, R2', R3, R3', R5, R5', R6, m, n, or p are as defined herein, are useful for treating flaviviridae viral...  
WO/2011/048112A1
This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabete...  
WO/2008/087558A3
The present invention comprises compounds useful as antiviral or antitumor agents. The compounds comprise nucleotide analogues that comprise tetrahydrofuranyl or tetrahydrothienyl moeities with quaternary centers at the 3' position. The ...  
WO/2008/080988A3
The present invention relates to cyclopentanone derivatives of formula (I), their method of synthesis and uses thereof. Also, the present invention relates to the use of cyclopentanone derivatives of formula (Ia). Concretely, the compoun...  
WO/2010/135427A3
Monomeric and dimeric trioxane fluoroaryl amides, 5-carbon-linked, C-10 non-acetal trioxane dimer esters; trioxane silylamides; and trioxane dimer orthoesters and methods of their use for treating subjects infected with malaria or other ...  
WO/2011/045240A1
The invention relates to novel amides and thioamides, to a method for the production thereof, and to the use thereof for combating animal pests, primarily arthropods and in particular insects.  
WO/2011/016050A3
The present invention relates to novel compounds of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvat...  
WO/2011/036074A1
The invention relates to aminoquinazoline compounds or the enantiomers or veterinarily acceptable salts thereof which are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention ...  
WO/2010/142663A8
The present invention relates to a compound with the following general formula (I): in which: R1 is a hydrocarbon chain of an unsaturated fatty acid from C12 to C24 including at least one unsaturation; and R2 and R3 are, independently or...  
WO/2011/033265A1
The invention relates to a series of compounds with particular activity as inhibitors of the serine-threonine kinase AKT. Also provided are pharmaceutical compositions comprising same as well as methods for treating cancer.  
WO/2011/034202A1
Disclosed is a photochromic chromene compound which is a compound (formula (1)) having an indeno(2,1-f)naphtho(1,2-b)pyran structure as a basic skeleton, wherein the structure has an aryl group or heteroaryl group (R1 group) bonded to th...  
WO/2011/034078A1
Disclosed is a compound which is useful as the active ingredient of a medicinal composition, in particular, a medicinal composition for preventing and/or treating a VAP-1 associated disease. As the results of intensive studies on compoun...  
WO/2011/030992A1
The present invention relates to a curable bicyclic compound derived from biomass, to a solvent-free curable composition, and to a method for preparing same, wherein the curable compound derived from biomass according to the present inve...  
WO/2011/030068A1
The invention relates to a compound derived from indole, especially useful in therapy, characterised in that it is selected from i) the compounds of formula (I), and ii) the pharmaceutically acceptable salts of said compounds of formula ...  
WO/2011/028741A1
A compound of formula (I) wherein A, X, Y, Z, R1 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other d...  
WO/2011/028927A1
Described herein are compounds of the formula useful as antagonists of sphingosine-1- phosphate receptors. Further described herein is the use of these compounds and related pharmaceutical compositions to treat disorders associated with ...  
WO/2011/027289A1
The present invention relates to chromone derivatives, their preparation, their pharmaceutical compositions and their application as D3 dopaminergic ligands as a medicament for disorders of the central nervous system.  
WO/2010/121226A3
The present disclosure relates generally to compositions and methods for treating cancer. In some aspects, novel spirohexenolides and methods of using and producing them are described.  
WO/2011/023722A1
The present invention relates to novel hepcidin antagonists of the general formula (I), to pharmaceutical compositions comprising them and to the use thereof as medicaments, especially for treatment of iron metabolism disorders, such as ...  
WO/2011/023812A1
A compound of formula (I): as well as pharmaceutically acceptable salts thereof, and a pharmaceutical composition comprising the compound. The compound is useful for the treatment of disorder selected from inflammatory diseases, nocicept...  
WO/2011/026153A2
Optimal compositions of derivatives of 5-methyl-3(2H)-furanone compounds and phenylpropanoid polyketides related to inotilone, that exert biological response modification in health and disease, and their method of preparation, are disclo...  

Matches 701 - 750 out of 6,886