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Matches 401 - 450 out of 6,885

Document Document Title
WO/2014/157009A1
The purpose of the present invention is to provide a photoelectric conversion element which exhibits excellent responsivity and heat resistance. A photoelectric conversion element of the present invention is obtained by sequentially lami...  
WO/2013/082345A9
The present invention provides compounds of Formula (I), or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyltransferase type 2 (M...  
WO/2014/153214A1
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting arginine methyltransferase activity. Methods of using...  
WO/2014/146553A1
The present invention belongs to the field of pharmaceutical chemistry, and, in particular, disclosed therein are a flavonoid derivative and use thereof. Disclosed is a flavonoid derivative having the structure of general formula (I) or ...  
WO/2014/145713A2
This disclosure relates generally to aminoglycoside derivatives of Formula (I) as described herein. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating bacterial infection...  
WO/2014/140081A1
This invention relates to bicyclic 1-carboxylic-acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and their use in methods of treatment and/or prev...  
WO/2014/135355A1
The invention relates to an isononyl ester or isononyl ester mixture of an epoxidized fatty acid or an epoxidized fatty acid mixture, the fatty acid or fatty acid mixture being extracted from tall oil or linseed oil and the average numbe...  
WO/2014/138302A1
A new class of antibiotics effective against methicillin-resistant Staphylococcus aureus (MRSA) is disclosed. Compounds of this class can impair cell-wall biosynthesis by binding to both the allosteric and the catalytic domains of penici...  
WO/2014/135674A1
The present invention relates to substituted chroman-6-yloxy-cycloalkanes of the formula (I) in which Ar, R1 to R4, p and q are as defined in the claims. The compounds of the formula (I) are inhibitors of the sodium-calcium exchanger (NC...  
WO/2013/134085A8
The present invention relates to spirocyclic acylguanidines and their use as inhibitors of the β-secretase enzyme (BACEl) activity, pharmaceutical compositions containing the same, and methods of using the same as therapeutic agents in ...  
WO/2014/128612A1
The invention relates to quinazolin-4-one compounds of the formula (I) and/or pharmaceutically acceptable salts and/or solvates thereof, Formula (I) wherein R1, R2, R3, R5, R6 and L are as defined in the description. Such compounds are s...  
WO/2014/129701A1
Provided are a monomer for a hardmask composition which is represented by chemical formula 1, a hardmask composition comprising the monomer and a pattern forming method using the hardmask composition.  
WO/2014/126070A1
Provided is a novel herbicide having a significant herbicidal activity on undesirable plants. A compound represented by general formula (I) [wherein R1 represents a C1-6 alkyl group, a C2-6 alkenyl group, a C2-6 alkynyl group, a C3-6 cyc...  
WO/2014/124220A1
Naturally-derived compounds having various structures elicit the perception of salty taste, enhance the perception of salty taste of a salt, or act at one or more sodium channels. Food products may include such naturally-derived compound...  
WO/2014/122530A1
Embodiments of the present invention relate to 4-(phenoxymethyl)-1,3-dioxolane analogs and pharmaceutical compositions thereof having a disease-modifying action in the treatment of diseases associated with the overproduction of Cortisol ...  
WO/2014/124207A1
Naturally-derived compounds having various structures elicit the perception of salty taste, enhance the perception of salty taste of a salt, or act at one or more sodium channels. Food products may include such naturally-derived compound...  
WO/2014/124191A1
Naturally-derived compounds having various structures elicit the perception of salty taste, enhance the perception of salty taste of a salt, or act at one or more sodium channels. Food products may include such naturally-derived compound...  
WO/2014/124214A1
Naturally-derived compounds having various structures elicit the perception of salty taste, enhance the perception of salty taste of a salt, or act at one or more sodium channels. Food products may include such naturally-derived compound...  
WO/2014/119892A1
The present disclosure relates to a novel method for preparing an arylnaphthalene lignan compound. In synthesis of arylnaphthalene lignan compounds and derivatives according to the present disclosure, a naphthalene backbone may be constr...  
WO/2014/116669A1
Epoxy containing phosphonate monomers, polymers, copolymers, oligomers and co-oligomers and methods for making the same are describes herein. These materials can be used to make polymers, and can be combined with other polymers, oligomer...  
WO/2014/113427A2
The present invention is directed to irciniastatin analogues. Uses of these analogues also described.  
WO/2014/108011A1
The present invention relates to important intermediate 2 of entecavir and a method for preparing entecavir intermediate compound 1 through ring-closing reaction of compound 2 under the condition of free radicals with transition metals a...  
WO/2014/104720A1
The present invention relates to an organic electroluminescent compound and an organic electroluminescent device comprising the same. By using the organic electroluminescent compound according to the present invention, an organic electro...  
WO/2014/094544A1
Provided are a phenyl C-glucoside derivative containing a deoxyglucose structure as represented by formula I, preparation method thereof, pharmaceutical composition containing same, and uses thereof in the preparation of drugs for treati...  
WO/2014/096864A1
The present subject matter relates generally to compounds having the formula (I): wherein each of X, Y, R1, R2, R3, R4, and n are as defined herein. Compounds of formula (I) may act as inhibitors of the thioredoxin reductase enzyme syste...  
WO/2014/097041A1
This invention relates to compounds of general Formula (I) in which R1, R2, U, V, L, M, R5, m, X, Y and Z are as defined herein, and the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds ...  
WO/2014/098597A1
The invention relates to novel bis-chromone derivatives, methods for their preparation and their therapeutic application, especially in the treatment or prevention of disease involving mast cell activation, such as allergic disease. Prov...  
WO/2014/100734A1
Described herein are compounds of formula (A), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compound...  
WO/2014/088290A1
The present invention relates to a novel organic electroluminescent compound and an organic electroluminescent device comprising the same. Using the organic electroluminescent compound according to the present invention, an organic elect...  
WO/2014/086712A1
The present invention relates to compounds of general formula I, wherein the groups (Het)Ar and R1 are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activ...  
WO/2014/062733A3
The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutic...  
WO/2014/086865A1
The present invention relates to inhibitors of the phosphodiesterase 4 (PDE4) enzyme. More particularly, the invention relates to 1-phenyl-2-pyridinyl alkyl alcohol derivatives, to processes for the preparation thereof, compositions comp...  
WO/2014/086284A1
Disclosed in the invention are a deuterated 3-cyano quinoline compound or pharmaceutically acceptable salts, solvates, prodrugs, stereoisomers, tautomers, polymorphic substances, metabolites etc., and a pharmaceutical composition contain...  
WO/2014/086894A1
The present invention relates to novel retinoid-related orphan receptor gamma (RORϒ) modulators and their use in the treatment of diseases mediated by RORϒ.  
WO/2014/082889A1
Disclosed are compounds of Formula I or pharmaceutically acceptable salts thereof, wherein X1, X2, X3, R1, R2 and R3 are as described in this application, methods for making said compounds as well as methods of using them in the treatmen...  
WO/2014/084407A1
The present invention provides a compound having an excellent efficacy for controlling weeds. A dihydropyrone compound of formula (I): wherein m is 1, 2 or 3; n is an integer of any one of 1 to 5; X represents O, S, S(O) or S(O)2; R1 rep...  
WO/2014/079803A1
The present invention relates to compounds of formula (la) or (lb) or pharmaceutically acceptable salts thereof for use in the treatment or prevention of hairloss, formula (Ia), (Ib) wherein Ra, Rb, Rc, Rd, Y1, Y2, Y3, Y4, Y5, Z, R1, R2,...  
WO/2014/074675A1
Compounds having the following formula (I) or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R2 is a monocyclic heteroaryl group, and R1, R3, R4, R5 and R6 are as defined herein, are useful as kinase modulators, in...  
WO/2014/044488A3
The invention relates to an ester and ester mixtures with at least one epoxide group and at least one carbonate group on the acid chain. The invention also relates to a method for producing said type of ester and to the use of the ester ...  
WO/2014/071044A1
The invention relates to compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein R', R1 through R7 and Ar are as defined herein. These compounds are useful as inhibitors of phosphodiesterase 10 (PDE10A) which are ...  
WO/2014/065209A1
Provided are: a pyridine compound or a salt thereof that has excellent insecticidal activity and/or acaricidal activity, is highly safe, and can be synthesized industrially advantageously; and a pest control agent including the same as a...  
WO/2014/064149A1
There are provided substituted 4-carboxamido-isoindolinone derivatives which selectively inhibit the activity of poly (ADP-ribose) polymerase PARP-1 with respect to poly (ADP-ribose) polymerase PARP-2. The compounds of this invention are...  
WO/2014/062732A1
The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutic...  
WO/2014/061764A1
A compound having an exceptional blood-sugar-reducing effect and represented by general formula (I), and a pharmaceutically acceptable salt thereof. In the formula, X is =C(R8)-, -CH(R8)-, =N-, or -O-; Y is =C(R9)-, -CH(R9)-, or =N-; Z i...  
WO/2014/058037A1
The present invention provides a compound having an excellent efficacy for controlling weeds. A pyrone compound of formula (I): wherein m is 1, 2 or 3; n is an integer of any one of 1 to 5; X represents O, S, S(O) or S(O)2; R1 represents...  
WO/2014/058078A1
Disclosed is a process for preparing dihydro-2H-pyran derivatives of formula I: wherein R1 and R2 are defined herein. The process of the invention provides the compound of formula I in concise cascade reactions and in one pot. The compou...  
WO/2013/061004A8
The present invention relates to novel disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds corresponding to the following general formula (I): , to the pharmaceutical compositions containing these compounds and also to the use of...  
WO/2014/056938A1
The present invention relates to pyrrolidinone derivatives of formula (I). The pyrrolidinone derivatives of formula (I) are GPR119 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related d...  
WO/2014/049488A1
This invention relates to compounds of general formula (I), in which R1, R2, R6, U, V, W, X, Y and Z are as defined herein, and the pharmaceutically acceptable salts thereof, pharmaceutical compositions containing such compounds and salt...  
WO/2014/050894A1
The present invention provides the compound represented by formula (1) (in the formula: X1 and X2 each independently represent -OR1, -NR2R3, -CR4R5R6, or the like; R1, R2, R3, R4, R5, and R6 each independently represent a glycosyl group ...  

Matches 401 - 450 out of 6,885