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Matches 1 - 50 out of 29,946

Document Document Title
WO/2018/002847A1
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, aza-substituted triterpenoid compounds that possess unique antiviral activity are provided as HIV matu...  
WO/2018/006077A1
The invention provides novel chemical compounds useful for treating pain or a related disease or disorder thereof, and pharmaceutical composition and methods of preparation and use thereof.  
WO/2018/003924A1
Provided is a novel pest control agent, especially a bactericide or a nematicide. An alkynylpyridine-substituted amide compound represented by formula (I) or a salt thereof; and a pest control agent which contains the compound or the sal...  
WO/2018/004095A1
The present invention relates to a compound, for an organic optoelectronic device, expressed by chemical formula (1), a composition for an organic optoelectronic device, an organic optoelectronic device having applied same, and a display...  
WO/2018/004096A1
The present invention relates to a compound, for an organic optoelectronic device, expressed by chemical formula (1), a composition for an organic optoelectronic device, an organic optoelectronic device having applied same, and a display...  
WO/2018/002848A1
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, azadecaline derivatives that possess unique antiviral activity are provided as HIV maturation inhibito...  
WO/2018/003842A1
The present invention addresses the problem of providing a novel electro-optic polymer. The present invention also addresses the problem of providing a novel electro-optic polymer in which the blended proportion of an alicyclic methacryl...  
WO/2017/222915A1
This invention is directed to novel heterocyclic prolinamide derivatives of Formula (I), and pharmaceutically acceptable salts, solvates, solvates of the salt and prodrugs thereof, useful in the prevention (e.g., delaying the onset of or...  
WO/2017/223407A1
The present invention is a conjugated polymer that contains both Unit (I) and Unit (II) is shown below: X, in each occurrence, is independently selected from S or Se. M1 and M2 are independently selected from H or F. R1 and R2 are indepe...  
WO/2017/221163A1
The present invention provides novel crystalline polymorphic form of DL-lactate salt of Panobinostat of Formula-I. This invention also provides process for preparation of crystalline forms of Panobinostat DL-lactate. Further, the present...  
WO/2017/216168A1
The present invention concerns a composition comprising at least one crystalline organic semiconductor and at least one compound of formula wherein R1R2, R3, R4, R5, R6, R7 and R8, which may be the same or different, represent H or a C1-...  
WO/2017/216661A1
The present invention relates to a process for the preparation of 7-{4-[4-(1-benzothiophen-4-yl)piperazin-1-yl]butoxy} quinolin-2(1H)-one (brexpiprazole) from 7-(4-chlorobutoxy)quinolin-2(1H)-one and 1-(benzo[b]thiophen-4-yl)piperazine. ...  
WO/2017/218633A1
The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.  
WO/2017/217792A1
The present invention relates to an improved method for producing a diphenylmethane derivative which is effective as a sodium-dependent glucose cotransporter (SGLT) inhibitor, the method being carried out by means of a convergent synthes...  
WO/2017/218843A1
The present disclosure relates generally to LRRK2 inhibitors, or a pharmaceutically acceptable salt, deuterated analog, prodrug, tautomer, stereoisomer, or mixture of stereoisomers thereof, and methods of making and using thereof. (Formu...  
WO/2017/208965A1
The present invention provides an organic compound characterized by being represented by general formula [1] set forth in the claims. In general formula [1], Ar1 and Ar2 are each independently selected from among aryl groups having 6-18 ...  
WO/2017/208251A1
The present invention relates to a new crystalline polymorph of brexpiprazole. More specifically, the invention relates to novel Form M of brexpiprazole, process for preparing the novel form of brexpiprazole and pharmaceutical formulatio...  
WO/2017/210545A1
Provided are novel compounds of Formula (I): and pharmaceutically acceptable salts thereof, which are useful for treating a variety of diseases, disorders or conditions which can be affected by potassium channel modulation. Also provided...  
WO/2017/205536A2
The present invention relates to compounds of formula (I) and formula (II): and to salts thereof, wherein R1-R4 of formula (I) and R5-R6 of formula (II) have any of the values defined herein, and compositions and uses thereof. The compou...  
WO/2017/205536A3
The present invention relates to compounds of formula (I) and formula (II): and to salts thereof, and compositions and uses thereof. The compounds are useful as inhibitors of CBP and/or EP300. Also included are pharmaceutical composition...  
WO/2017/202798A1
The present invention provides novel compounds having the general formula (I) wherein R1 to R6, X, Y, A1 and A2 are as described herein, compositions including the compounds and methods of using the compounds.  
WO/2017/202291A1
The present invention discloses a thiophene used as a uric acid transporter (URAT1) inhibitor and application of the thiophene in preparing a pharmaceutical product for treating a disease related to abnormal uric acid levels, specificall...  
WO/2017/205610A1
The invention relates to a new use of compounds that are angiotensin II receptor agonists, more particularly selective agonists of the angiotensin II type 2 receptor (the AT2 receptor), and especially agonists that bind selectively to th...  
WO/2017/203456A1
The present invention relates to stable topical compositions comprising Luliconazole. Further the present invention also relates to stable topical compositions comprising combination of luliconazole with a corticosteroid such as betameth...  
WO/2017/193951A1
Disclosed are a class of compounds as a caspase inhibitor, and in particular the compound as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the use of the compound in treating caspase-related diseases.  
WO/2017/194002A1
Disclosed are a crystal form of Brexpiprazole and a preparation method therefor. The X-ray powder diffraction pattern, which is detected with Cu-K α radiation, of the crystal form of Brexpiprazole has characteristic peaks at the positio...  
WO/2017/195113A1
Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infect...  
WO/2017/191098A1
Compounds of Formula (I): and salts thereof, and methods of use as Janus kinase inhibitors are described herein.  
WO/2017/192485A1
Compounds of Formula I and Formula II, pharmaceutically acceptable salts thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other condition...  
WO/2017/192929A1
The invention provides substituted pyrrolo[1,2-α]triazine compounds, related compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gauche...  
WO/2017/192304A1
The present disclosure is directed to compounds of formula (I): or a pharmaceutically acceptable salt, solvate or solvate of the salt thereof. Compounds of formula (I) are inhibitors of NOX4 and are useful in the treatment of fibrotic di...  
WO/2017/191562A1
The present invention is directed to process for preparation of Olaparib of formula (I). The present invention further relates to novel polymorphic forms of Olaparib, pharmaceutical compositions containing them, and method of treatment u...  
WO/2017/181973A1
The invention provides a 5-member heterocycle and a manufacturing method, pharmaceutical composition, and application thereof. Specifically, the invention provides a compound represented by formula (I). Various radicals are as defined in...  
WO/2017/181974A1
Provided are a five-membered heterocyclic compound, a preparation method therefor, a pharmaceutical composition and a use. Specifically, provided is a compound having formula (I), the definitions of the various groups being laid out in t...  
WO/2017/182464A1
The present invention relates to compounds of formula (I); which are capable of inhibiting the 11-beta-hydroxysteroid dehydrogenase type 1 (11- beta-HSD1), to processes for preparing these compounds, to pharmaceutical compositions compri...  
WO/2017/184658A1
The present disclosure relates to compounds of formula I which inhibit NaV1.7, and include pharmaceutically acceptable salts, compositions comprising such compounds, and methods using and making such compounds and compositions.  
WO/2017/178510A1
The present invention relates to arylamide derivatives having dual pharmacological activity towards both the α2δ subunit, in particular the α2δ-1 subunit,of the voltage-gated calcium channel and the µ-opioid receptor, to processes o...  
WO/2017/180571A1
Disclosed are substituted benzothiophenyl derivatives, compositions and methods for treating of disorders that are affected by the modulation of the GPR40 receptor such as Type II diabetes mellitus. Such compounds are represented by Form...  
WO/2017/181004A1
The disclosure of a compound of Formula (I) or a pharmaceutically acceptable salt thereof (I) The variables W, R1, R2, R3, and R4 are defined in the disclosure. The disclosure provides a compound or salt of Formula (I) together with a ph...  
WO/2017/179926A1
The present invention relates to a novel benzothiophene derivative, a pharmaceutically acceptable salt thereof or an optical isomer thereof, a method for preparing same, and a pharmaceutical composition, containing same as an active ingr...  
WO/2017/178311A1
The present invention relates to dibenzofuran and dibenzothiophene derivatives which are substituted with electron-transporting groups, in particular for use as triplet matrix materials in electronic devices. The invention also relates t...  
WO/2017/177974A1
Disclosed is a compound for treating fibrosis-related diseases, and specifically disclosed are the compound represented by formula (I) and a pharmaceutically acceptable salt thereof.  
WO/2017/174995A1
There are provided compounds of formula I, (I) wherein T, A, Q, Z, G, R4, R5a, R5b and n have meanings given in the description, which compounds have antiinflammatory activity (e.g. through inhibition of one or more of members of: the fa...  
WO/2017/176981A1
Small molecule regulators of steroid receptor coactivator (SRC) family proteins are provided, as well as methods for their use in treating or preventing SRC-related diseases. The SRC-related diseases can include cancer, metabolic disorde...  
WO/2017/174620A1
The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.  
WO/2017/175842A1
Provided are a compound and a pharmaceutical composition pertaining to the modification of splicing, the use of these, or a method for preventing, improving, suppressing the advance of, and/or treating a genetic disease in which the comp...  
WO/2017/167182A1
The present invention provides a compound represented by formula (I), or a pharmaceutically acceptable salt, a solvate, an ester, an acid, a metabolite or a prodrug thereof. The compound itself in the present invention or in combination ...  
WO/2017/169355A1
Provided is an organic EL element which is low voltage while exhibiting high light-emission efficiency and high drive stability. Thus, an organic electroluminescent element obtained by layering a positive electrode, an organic layer and ...  
WO/2017/171421A1
The present invention relates to a novel pyrimidine-4-carboxylic acid derivative having an anticancer activity, and the compound of the present invention is useful as a drug for treating and preventing tumor diseases.  
WO/2017/169785A1
Provided is an organic EL element which is low voltage and has practical use utility while exhibiting high light emission efficiency and drive stability. Thus, an organic electroluminescent element obtained by layering a positive electro...  

Matches 1 - 50 out of 29,946