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Matches 1 - 50 out of 30,469

Document Document Title
WO/2018/164214A1
The purpose of the present invention is to provide an auxin derivative capable of efficiently exerting a desired effect while reducing undesired effects. A compound represented by general formula (1) which has specific substituent(s) at ...  
WO/2018/164192A1
The present invention provides a substituted pyrrolidine compound having orexin-2 receptor agonistic activity. A compound represented by formula (I) (wherein the symbols are as described in the description) or a salt thereof has orexin-2...  
WO/2018/164545A1
The present invention provides a novel compound and an organic light emitting element using the same.  
WO/2018/162581A1
The present invention relates to desmethylanethole trithione ( AOX ) and derivatives thereof, especially derivatives of formula (I), for the prevention and treatment of diseases whose initiation and/or evolution relates to the production...  
WO/2018/162880A1
The present invention relates to a 1, 4 bidentate ligand comprising first and second ligand centres, wherein the first ligand centre is an sp2-hybridised carbon or a nitrogen atom; wherein the second ligand centre is a nitrogen atom in a...  
WO/2018/160022A1
The present disclosure relates to an organic electroluminescent device. The organic electroluminescent device of the present disclosure comprises a specific combination of a light-emitting layer and an electron transport zone, thereby pr...  
WO/2018/159964A1
The present disclosure relates to an organic electroluminescent compound and an organic electroluminescent device comprising the same. By comprising the organic electroluminescent compound of the present disclosure, it is possible to pro...  
WO/2018/159970A1
The present disclosure relates to an organic electroluminescent device comprising a light-emitting layer and a hole transport zone. By comprising a specific combination of a light-emitting layer and a hole transport zone, it is possible ...  
WO/2018/161033A1
Described herein are IRE1-alpha inhibitors, compositions containing such inhibitors, and methods of treatment of cancer that include administration of such compounds. Exemplary compounds are provided throughout the application.  
WO/2018/160944A1
Method and compounds for treating cancer by, for example, modulating immune system activity, are provided.  
WO/2018/157981A1
The present invention relates to triarylamine compounds of general formula (I). The present invention further relates to methods for producing said compounds, oligomers, polymers or dendrimers and to formulations containing said compound...  
WO/2018/159796A1
Provided is a novel diarylethene compound which is discolored when irradiated with ultraviolet light, and which does not change color much under visible light after the discoloration. A diarylethene compound according to the present inve...  
WO/2018/154578A1
Compounds represented by general Formulae I to IV as described herein are disclosed. Further disclosed are composition utilizing the herein disclosed compounds and using the same for the treatment of glycogen storage disorders.  
WO/2018/153767A1
Process for the preparation of methyl-4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-tri azole-1-yl)carbonyl)sulphamoyl]-5-methylthiophene-3-carboxyl ate. The invention relates to a process for the preparation of methyl-4-[(4,5-dihydr...  
WO/2018/149857A1
The present invention relates to novel 2-oxo-2H-chromen compounds, particularly to compounds comprising a photoactive unit, said novel compounds being particularly suitable for compositions and ophthalmic devices as well as to compositio...  
WO/2018/149856A1
The present invention relates to novel compounds, particularly to compounds comprising a photoactive unit, said novel compounds being particularly suitable for compositions and ophthalmic devices as well as tocompositions and ophthalmic ...  
WO/2018/151520A1
The present disclosure relates to an organic electroluminescent compound and an organic electroluminescent device comprising the same. The organic electroluminescent compound of the present disclosure has a high glass transition temperat...  
WO/2018/150421A1
The invention provides efficient cyclization processes of hydroxyalkenoic acids and products produced therefrom. The following reactions are claimed: Formula (I), (II), (V) and (VI).  
WO/2018/149853A1
The present invention relates to novel compounds, particularly to compounds comprising a photoactive unit, said novel compounds being particularly suitable for compositions and ophthalmic devices as well as to compositions and ophthalmic...  
WO/2018/149991A1
The present invention relates to particular sulfonamide derivatives, the pharmaceutically acceptable addition salts thereof, the hydrates thereof and/or the solvates thereof, and also the use thereof as inverse agonists of retinoid-relat...  
WO/2018/149852A1
The present invention relates to novel compounds (I) particularly to compounds comprising a photoactive unit, said novel compounds being particularly suitable for compositions and ophthalmic devices as well as to compositions and ophthal...  
WO/2018/149327A1
Disclosed is a method for preparing a canagliflozin form. The method comprises the following steps: adding canagliflozin into an organic solvent and dissolving same, then distilling into a certain amount of an oil; then, adding an anti-s...  
WO/2018/150347A1
The present invention relates to novel compounds of formula (I), its pharmaceutically acceptable salts, and isomers, stereoisomers, atropisomers, conformers, tautomers, atropisomers, polymorphs, hydrates, solvates, N-oxide or S-oxide the...  
WO/2018/146010A1
The present invention covers 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamide compounds of general formula (I), in which X, R1, R2, R3, R4 and R5 are as defined herein, methods of preparing said compounds, intermediate compounds us...  
WO/2018/145550A1
Disclosed is an aza-spirobifluorene derivative characterized by the following structural formula: formula (1), where only one of X1, X2, X3, and X4 is a nitrogen atom while the other three are carbon atoms, R is an aromatic or heteroarom...  
WO/2018/143591A2
A compound according to various embodiments of the present invention is expressed by chemical formula 1 below. In chemical formula 1, X is O or S; R1 and R2 each are independently selected from the group consisting of aryl, heteroaryl, a...  
WO/2018/141886A1
The present invention relates to crystalline brexpiprazole having a particle size distribution (PSD) characterized by a d(90) of 30 μm to 100 μm, by a d(10) of at least 1.0 μm, and by a d(4,3) of at least 15.0 μm. The present inventi...  
WO/2018/139174A1
A fluoroether compound represented by formula (1). R1-R2-CH2-R3-CH2-R4-R5 (1) (In formula (1), R1 and R5 may be the same or different and are each a group having a heteroring, R2 and R4 may be the same or different and are each a divalen...  
WO/2018/140809A1
The present disclosure relates to bifunctional compounds, which find utility as modulators of estrogen receptor (target protein). In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a cer...  
WO/2018/138028A1
The present invention relates to compounds of general formula (I), wherein the groups R, R1, R2, R3, m and n are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate...  
WO/2018/138039A1
The present invention relates to carbazole derivatives, particularly for use in electronic devices. The invention further relates to a method for producing the compounds according to the invention and to electronic devices comprising the...  
WO/2018/138027A1
The present invention relates to compounds of general formula (I), wherein the groups R, R1, R2, R3, m and n are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate...  
WO/2018/140578A1
Described herein are molecules for use in organic photovoltaic devices. Example molecules comprise at least one core moiety, two spacer moieties, and two terminal moieties. Values and preferred values of the core, spacer, and terminal mo...  
WO/2018/138246A1
The invention relates to dimer diol dilipoate, to the method for the production thereof, to the use of same as an anti-wear additive, a friction modifier additive and/or an extreme pressure additive, and to the compositions comprising sa...  
WO/2018/137639A1
The invention relates to a histone methyltransferase EZH2 inhibitor, a preparation method and pharmaceutical use thereof. In particular, the invention relates to a compound represented by the general formula (I), a preparation method the...  
WO/2018/139767A1
The present invention provides a novel amine-based compound and an organic light emitting device using the same.  
WO/2018/138026A1
The present invention relates to compounds of general formula (I) wherein the groups R, R1, R2, R3, m and n are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate ...  
WO/2018/134510A1
The present invention relates to a method for the preparation of substituted thiolactones of formula (I), substituted thiolactones of formula (I') that can be obtained by implementing said method, the use of substituted thiolactones of f...  
WO/2018/133795A1
An inhibitor of a wild type and Y641F mutant of human histone methyltransferase EZH2. Particularly, the inhibitor is a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. The inhibitor can be used to treat ...  
WO/2018/133579A1
Provided in the present invention are a ruthenium metal complex of which the molecular formula is L3Ir, applications thereof, and an organic electroluminescent component, where Ir is the center metal atom, L is a ligand, and the structur...  
WO/2018/135798A1
The present invention provides a novel heterocyclic compound and an organic light emitting element using the same.  
WO/2018/131866A1
The present disclosure relates to an organic electroluminescent device. The organic electroluminescent device of the present disclosure can exhibit low driving voltage, high efficiency and/or long lifespan by comprising a specific combin...  
WO/2018/130184A1
The present invention relates to a 1,2,4-triazine-3-amine derivative, a preparation therefor, and use thereof in medicine. Specifically, the present invention relates to a 1,2,4-triazine-3-amine derivative as represented by general formu...  
WO/2018/130207A1
The present invention pertains to the field of pharmaceutical chemicals, and discloses a 4,4-diphenyl piperidine compound or a pharmaceutically acceptable salt thereof, a pharmaceutical composition using the same, and a use thereof. Spec...  
WO/2018/130625A1
The present invention relates to novel substituted benzene disulfonamides, as well as pharmaceutical compositions containing at least one of these substituted benzene disulfonamides together with at least one pharmaceutically acceptable ...  
WO/2018/132636A1
The present invention provides a compound having the structure: (Formula I), and a method of inhibiting Glycogen synthase kinase-3 β (GSK-3β) in a subject comprising administering to the subject said compound, so as to thereby inhibit ...  
WO/2018/121434A1
Disclosed is an aryl hydrocarbon receptor modulator as represented by formula (I) and a pharmaceutically acceptable salt. R' is H, CN, CH2(OH)R0, CmH2m+1, CnH2n-1, CnH2n-3, formula (A), formula (B), or formula (C); two Ra are independent...  
WO/2018/121607A1
Disclosed are a benzo[b]thiophene amide derivative and the use thereof. In particular, the present invention relates to a benzo[b]thiophene amide derivative having a structure of formula (I) or a pharmaceutically acceptable salt thereof,...  
WO/2018/124088A1
Provided are novel pest control agents, in particular, a bactericide and a nematicide. An alkylphenyl-substituted amide compound represented by formula (I) [wherein: G1 stands for a structure represented by G1-2, G1-3, G1-4, etc.; X1 sta...  
WO/2018/122317A1
New Antiviral Drugs and Uses thereof. The present invention relates to a new class of compounds of formula (I) having an antiviral effect and the uses thereof.  

Matches 1 - 50 out of 30,469