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Matches 1 - 50 out of 35,652

Document Document Title
WO/2018/187652A1
The present invention relates to 2,4-diaminopyrimidines of formula (I) and pharmaceutically acceptable salts thereof, purification methods for the same, pharmaceutical compositions containing them, methods of obtaining and using them for...  
WO/2018/184985A1
Compounds of the formula (I): wherein the substituents are as defined in claim 1, useful as a pesticides, especially as fungicides.  
WO/2018/184988A1
Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as pesticides, especially as fungicides.  
WO/2018/184890A1
Described are substituted pyrrolidinones of general formula (I) and the use thereof as herbicides, in particular for controlling weeds and/or weed grasses in crops of useful plants and/or as plant growth regulators for influencing the gr...  
WO/2018/184392A1
The present invention provides formula I and formula II IDO inhibitors and preparation methods therefor, wherein R1, R2, and X groups are as defined in the specification. The present invention also provides a pharmaceutical composition c...  
WO/2018/184984A1
Compounds of the formula (I): wherein the substituents are as defined in claim 1, useful as pesticides, especially as fungicides.  
WO/2018/186365A1
The present invention relates to a novel read-through inducing agent, and also relates to a compound represented by general formula (I) (symbols in the formula are as described in the specification) or a pharmaceutically accepted salt th...  
WO/2018/181345A1
Provided is a compound which has an Nrf2-activating activity and is expected to be useful as a prophylactic or therapeutic agent for diseases associated with oxidative stress, particularly hepatitis (e.g., non-alcoholic steatohepatitis (...  
WO/2018/181847A1
The purpose of the present invention is to provide a novel aromatic compound capable of having GPR40 agonistic activity and activity in accelerating GLP-1 secretion. A compound represented by formula (I) (wherein the symbols are as defin...  
WO/2018/178304A1
Inhibitors of ALCAT1 are described having the general formula: (I). These compounds offer a treatment for aging and age-related diseases.  
WO/2018/178134A1
The present invention relates to a pharmaceutical formulation of (S)-[2-chloro-4-fluoro- -(7-morpholin-4-ylquinazolin-4-yl)phenyl]-(6-methoxy-pyridaz in-3-yl)methanol or pharmaceutically acceptable salt thereof, as well as a method of ma...  
WO/2018/183964A1
Isoquinoline compounds and their use as inhibitors of HPK1 (hematopoietic kinase 1) are described. The compounds are useful in treating HPK1 -dependent disorders and enhancing an immune response. Also described are methods of inhibiting ...  
WO/2018/175185A1
The present invention relates to oxazolidinone Compounds of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein A, E, and R1 are as defined herein. The present invention also relates to compositions which comprise at ...  
WO/2018/172480A1
Compounds of formula (I) wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, and their uses as insecticides.  
WO/2018/172471A1
The present invention relates to compounds of formula (I) wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds; to intermediate...  
WO/2018/172423A1
The invention relates to a compound which is an indane derivative according to Formula (I), or a pharmaceutically acceptable salt thereof, [FORMULA (I)] wherein R1, R2, R3, n, R4, p¸ q, L, ׇ, X and m are as defined herein. The compound...  
WO/2018/173058A1
The present invention provides processes for the preparation of diverse heterocyclic scaffolds from alpha-enaminone building bloc of formula (I).  
WO/2018/170664A1
Disclosed are oxazolidinone compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein A, E, and R1 are as defined herein. Disclosed herein also are compositions which comprise at least one oxazolidinone compound and...  
WO/2018/174170A1
A compound represented by formula (I) has an excellent controlling effect on arthropod pests. (In the formula, Q represents a group represented by formula Q1 or the like; A1 represents CR7 or the like; A2 represents NR8A or the like; A4 ...  
WO/2018/172997A1
A compound of Formula (I)) or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating hearing loss or balance disorder: Formula (I) wherein R1 through R3, and L are as defined herein.  
WO/2018/172477A1
The present invention relates to compounds of formula (I) wherein A1, A2, A3, A4, R1, R2, R3, R4 and n are as defined in claim 1; or a tautomer, isomer, enantiomer, salt or N-oxide thereof; to intermediates for preparing compounds of for...  
WO/2018/171173A1
The present invention relates to a method for synthesis of Eliglustat and intermediate compounds thereof. Specifically, the present invention relates to the field of synthesis of organic compounds, to a method for synthesis of Eliglustat...  
WO/2018/174288A1
To provide a useful novel compound exhibiting antimicrobial activity on the basis of inhibitory action of DNA gyrase GyrB and topoisomerase IV ParE. Provided is a 2(1h)-quinolinone derivative represented by formula (1), or a pharmaceutic...  
WO/2018/166934A1
The present invention relates to dibenzofuran and dibenzothiophene derivatives, in particular for use as triplet matrix materials in organic electroluminescent devices. The invention further relates to a method for producing the compound...  
WO/2018/170492A1
Compounds are provided that antagonize the kappa-opioid receptor (KOR) and products containing such compounds, as well as to methods of their use and synthesis. Such compounds have the structure of Formula (I), or a pharmaceutically acce...  
WO/2018/167695A1
The present invention relates to compounds of Formula (I) or pharmaceutically acceptable salts or solvates thereof. It further discloses a pharmaceutical composition comprising the compounds of Formula (I) and their uses, in particular t...  
WO/2018/168991A1
[Problem] The purpose of the present invention is to provide an organic EL element in which various materials for an organic EL element, which excel in hole injection/transport performance, electron injection/transport performance, elect...  
WO/2018/166855A1
The invention relates to novel compounds of formula I, wherein the variables are as defined in the specification, to compositions comprising them, to active compound combinations comprising them, and to their use for protecting growing p...  
WO/2018/166899A1
Provided are processes for the production of PF1022A derivative compounds, including incubating a microorganism strain capable of producing such compounds in a culture medium to produce a resulting culture, said culture medium containing...  
WO/2018/167019A1
The present invention encompasses compounds of formula (I), wherein the groups R1 to R, A1 to A4 and n have the meanings given in the claims and specification, their use as inhibitors of PHGDH, pharmaceutical compositions which contain c...  
WO/2018/169038A1
A plant disease control agent which contains a compound represented by formula (1) as an active ingredient.  
WO/2018/164191A1
The present invention provides a substituted pyrrolidine compound having orexin receptor type 2 agonist activity. A compound represented by the formula (in the formula, each symbol is as described in the specification) or a salt thereof ...  
WO/2018/162643A1
Compounds of the formula (I), wherein the substituents are as defined in claim 1, useful as pesticides, especially as fungicides.  
WO/2018/165501A1
The invention provides aryl indolinyl sulfonamide and related compounds, pharmaceutical compositions, methods of promoting RORγ activity and/or increasing the amount of IL-17 in a subject, and therapeutic uses of the indolinyl sulfonami...  
WO/2018/162581A1
The present invention relates to desmethylanethole trithione ( AOX ) and derivatives thereof, especially derivatives of formula (I), for the prevention and treatment of diseases whose initiation and/or evolution relates to the production...  
WO/2018/163077A1
The invention relates to indanyl compounds, their pharmaceutically acceptable salts thereof, processes for their preparation and pharmaceutical compositions comprising the same for the treatment, management and /or lessening severity of ...  
WO/2018/161876A1
The present invention relates to a dihydroquinoxaline bromodomain recognition protein inhibitor, a preparation method and a use thereof. The inhibitor of the present invention is a compound represented by general formula (I), or a stereo...  
WO/2018/165266A1
Described herein are pharmaceutical compositions adapted for the topical administration of macrolide antibiotics, and uses thereof in the treatment of dry eye diseases.  
WO/2018/162880A1
The present invention relates to a 1, 4 bidentate ligand comprising first and second ligand centres, wherein the first ligand centre is an sp2-hybridised carbon or a nitrogen atom; wherein the second ligand centre is a nitrogen atom in a...  
WO/2018/165520A1
Provided are compounds having HDAC6 modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by HDAC6.  
WO/2018/160022A1
The present disclosure relates to an organic electroluminescent device. The organic electroluminescent device of the present disclosure comprises a specific combination of a light-emitting layer and an electron transport zone, thereby pr...  
WO/2018/159835A1
The present invention provides a strigolactone receptor inhibitor for plants, which contains, as effective component, at least one triazole urea compound represented by formula (I); an agricultural composition; a method for using this ag...  
WO/2018/158210A1
The present invention is directed to pyridyl derivatives which are bromodomain inhibitors, pharmaceutical compositions comprising the compounds and the use of the compounds or the compositions in the treatment of various diseases or cond...  
WO/2018/157843A1
The preparation method provides 2-(substituted benzene matrix) aromatic formate FTO inhibitor, a preparation method therefor, and applications thereof. Specifically, disclosed in the present invention are a 2-(substituted benzene matrix)...  
WO/2018/158212A1
The present invention is directed to pyrazole derivatives, pharmaceutical compositions comprising the compounds and the use of the compounds or the compositions in the treatment of various diseases  
WO/2018/158365A1
Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as pesticides, especially as fungicides.  
WO/2018/159841A1
The purpose of the present invention is to develop an optical resolution reagent for which quenching does not occur in the analysis of a chiral amino acid. The problem is solved by providing a novel compound for optical resolution that d...  
WO/2018/155942A1
The present disclosure relates to a plurality of host materials and an organic electroluminescent device comprising the same. The organic electroluminescent device of the present disclosure can exhibit excellent lifespan characteristics ...  
WO/2018/153508A2
Compounds of formula (I) wherein A, R, W, Q, n and m have the meaning according to the claims can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.  
WO/2018/156684A1
Provided herein are compositions and methods for inhibiting the sublimation of solid compounds, such as 3,5-disubstituted-1,2,4-oxadiazoles, from the surface of a substrate (e.g., seeds).  

Matches 1 - 50 out of 35,652