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Matches 701 - 750 out of 6,422

Document Document Title
JP3911124B2  
JP2007510709A  
JP2007106684A
To provide a pharmaceutical preparation containing cefditoren pivoxil, having improved wettability with water and improved dissolution property and exhibiting high initial dissolution rate.The pharmaceutical composition comprises 0.1-10 ...  
JP2007077137A
To provide an industrial method for directly converting cefepime being a cephalosporin having a wide action spectrum into sterilized cefepime dihydrochloride monohydrate.The method for producing sterilized cefepime dihydrochloride monohy...  
JP2007077123A
To provide a cefdinir which solves a problem that conventional crystalline cefdinir is slightly soluble in water, and has high solubility in water.The present invention relates to amorphous cefdinir which does not contain crystalline cef...  
JP2007505895A  
JP3927262B2
To produce a specific new cephem compound capable of manifesting excellent antimicrobial activities against Gram-positive and Gram-negative bacteria including methicillin-resistant Staphylococcus aureus(MRSA) and useful as an antimicrobi...  
JP3920939B2
To obtain a new crystalline cephem acid addition salt with long half- life in the blood and excellent medicinal sustainability, useful for the treatment of bacterial infectious diseases. This compound is shown by formula I [(n) is 1 or 2...  
JP2007503447A  
JP3884063B2  
JP3914276B2
To obtain a specific new cephalosporin derivative having a substituted sulfonylmethyl group bonded to the 3-site of cephem ring, having a broad antibacterial spectrum and strong antibacterial action and useful for an antibacterial agent,...  
JP2007023046A
To provide new cepham compounds having antimicrobial activities, their production method, intermediates and a pharmaceutical composition containing the cepham compounds.The antibacterial compounds are expressed by formula I [in the formu...  
JP3872955B2  
JP2006528970A  
JP3863915B2  
JP3860750B2  
JP3852946B2  
JP2006525340A  
JP3836675B2  
JP3868008B2
PURPOSE: To obtain a new temp. and moisture stable compd. useful as a compsn. for injection. CONSTITUTION: This dihydrate of 7-[α-(2-aminothiazol-4-yl)-α-(Z)- methoxyiminoacetamide)-3-[(1-methyl-1-pyrrolidino)methyl]-3- cephem-4- carbo...  
JP3856807B2
To provide a beta-lactamase as a reporter gene, a beta-lactamase substrate compound and uses thereof for particularly monitoring expression from a pair of expression control sequences to screen a biochemical activity. Disclosed is a reco...  
JP2006521309A  
JP3850692B2
To provide a method of preparing a cephalosporin compound and an intermediate for preparation of these compound. This method cyclizes a compound of formula (III) to obtain a compound expressed by formula (II). [R1 is H, a methoxy or form...  
JP3837439B2
To obtain a new cephem compound having an excellent antibacterial power, especially exhibiting a storing antibacterial activity against MRSA, high in solubility in water, low in toxicity and high in safety. For this cephen compound, a ce...  
JP2006206529A
To provide a method for producing a compound represented by formula (1).The compound represented by formula (2) and its salts are found out as efficient synthetic intermediates of the above-mentioned compound. [Wherein, R is H, an alkyl ...  
JP2006515633A  
JP3777191B2  
JP2006514629A  
JP3791941B2
PURPOSE: To obtain the subject high-purity compound important as an intermediate for cephem-based antibiotic substances useful as an oral agent in high yield according to safe and simple operations by using a specific arenyl β-lactam co...  
JP2006096679A
To provide a new inexpensive manufacturing method of cefditoren.The manufacturing method of 7-[2-methoxyimino-2-(2-aminothiazol-4-yl)acetamide]-3-[2-(4- methylthiazol-5-yl)vinyl]-3-cefem-4-carboxylic acid (cefditoren) represented by form...  
JP2006511561A  
JP2006508984A  
JP2006508985A  
JP2006508093A  
JP3775819B2
PURPOSE: To obtain the subject high-purity compound useful as an antimicrobial agent having a wide range of antimicrobial spectra in high yield according to simple operations by using a specific halomethylcephem compound as a starting ra...  
JP3775836B2
To safely and easily produce a compound useful as a production intermediate for cephem antibiotics for oral administration in high yield and purity by reacting a specific allenyl β-lactam compound with a halogenation reagent in the pres...  
JP2006507289A  
JP2006507290A  
JP3751880B2  
JP2006506459A  
JP2006506337A  
JP3747328B2  
JP2006034950A
To provide a method and an agent for efficiently cleaning an institution and/or facilities used for manufacturing a substance capable of chemically reacting with a nucleophilic agent and/or a medicine.This is a method for cleaning an ins...  
JP3743680B2  
JP2006022042A
To provide a new crystal of cefcapene pivoxil, and to provide a method for producing an antibacterial agent using the same.This crystal of a compound (I) represented by the formula or its solvate. The crystal, wherein the solvent of the ...  
JP2006501305A  
JP3755908B2
PURPOSE: To obtain crystals of the subject compound excellent in fluidity, filling property and pressure resistance regardless of origin of raw materials, its producing method, existence or absence, or king of an impurity and difference ...  
JP2006500356A  
JP2005343854A
To provide an economically excellent method for producing 7-amino-3-[(Z)-2-(4-methylthiazol-5-yl)vinyl]-3-cephem-4-car boxylic acid having very low E type content and the salt thereof.The method for producing 7-amino-3-[(E/Z)-2-(4-methyl...  
JP2005343838A
To provide a 3-alkenylcephem compound useful as an intermediate for producing cefditoren pivoxil widely applied as an excellent antimicrobial agent, and to provide a method economically excellent, suitable for industrial production and f...  

Matches 701 - 750 out of 6,422