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Matches 1 - 50 out of 9,710

Document Document Title
WO/2019/165810A1
Disclosed is a method for preparing a thiazoloquinazolinone derivative. The invention adopts a 1-thiazolyl indole compound as a starting material that reacts in air to prepare the product. The raw material is easily available and widely ...  
WO/2019/166206A1
The present invention relates to an organic material and to an electronic device comprising the organic material, particularly to an electroluminescent device, particularly to an organic light emitting diode (OLED), wherein the semicondu...  
WO/2019/165073A1
The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of SHP2 phosphatase with the compounds and compositions of the disclosure. The present disclosure further ...  
WO/2019/086141A8
The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV rep...  
WO/2019/161078A1
Compounds of Formula (I), pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treat...  
WO/2019/158550A1
The present invention relates to a method for preparing tert-butyl N- ((1R,2S,5S)-2-((2-((5-chloropyridin-2-yl)amino)-2-oxoacetyl) amino) -5-(dimethylcarbamoyl)cyclohexyl)carbamate of formula (I), or a salt or solvate thereof,characteriz...  
WO/2019/158731A1
The invention relates to 6,5 heterobicyclic ring derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use for the treatment of inflammatory conditions driven by STING activation,...  
WO/2019/156987A1
Provided herein are compounds, compositions and methods of using the compounds and compositions for the treatment of diseases modulated, as least in part, by AhR. The compounds are represented by formulae: (I) wherein the letters and sym...  
WO/2019/126253A8
Disclosed are compounds of Formula (I) or salts thereof, wherein A, G, R1, R5, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmace...  
WO/2019/149205A1
The present invention relates to a benzoheteroaryl derivative and a preparation method and medical application thereof. In particular, the present invention relates to a novel benzoheteroaryl derivative represented by general formula (I)...  
WO/2019/146739A1
Provided is a novel compound which has D3 receptor antagonism. A compound represented by formula (IA)' (wherein: A represents S or O; R1a represents optionally substituted alkyloxy, etc.; R2a to R2d independently represent a hydrogen ato...  
WO/2019/141980A1
The present invention relates to picolinic acid derivatives that are useful in treating fungal diseases ofplants.  
WO/2019/138107A1
The present invention relates to compounds of Formula (I) inhibiting indoleamine 2,3-dioxygenase (IDO) and/or tryptophan 2,3-dioxygenase (TDO) enzymes. Further, their synthesis and their use as medicaments in inter alia the treatment of ...  
WO/2019/130274A1
An electro-optic cell for an electrochromic device includes an electrochromic medium including an electrochromic compound M having at least one reduced state and at least one oxidized state. The electrochromic compound M can act as both ...  
WO/2019/129025A1
The present invention discloses a tetrahydropyrrole compound, a preparation method therefor, a pharmaceutical composition containing the same, and a use thereof. The tetrahydropyrrole compound of the present invention is represented by g...  
WO/2019/133634A1
The present disclosure relates to chemical compounds that modulate pantothenate kinase (PanK) activity for the treatment of metabolic disorders (such as diabetes mellitus type II), neurologic disorders (such as pantothenate kinase-associ...  
WO/2019/126731A1
The invention relates to inhibitors of PI5P4K inhibitors useful in the treatment of cancers, neurodegenerative diseases, inflammatory disorders, and metabolic diseases, having the Formula: (I) where A, B, R1, X1, X2, and W are described ...  
WO/2019/126253A1
Disclosed are compounds of Formula (I) or salts thereof, wherein A, G, R1, R5, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmace...  
WO/2019/122320A1
The present disclosure relates to fungicidal active compounds, more specifically to heterocyclic benzosultams and analogues thereof, processes and, intermediates for their preparation and use thereof as fungicidal active compound, partic...  
WO/2019/119207A1
Provided are compounds of formula (I) which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.  
WO/2019/124548A1
The present invention provides a compound having an excellent control effect against harmful arthropods. The compound is represented by formula (I) [in the formula, Q represents a group or the like represented by formula Q1, Het represen...  
WO/2019/126567A1
Disclosed are heterocyclic-pyridinone analogs that are capable of inhibiting Nef-Hck and methods of treating viral infections such as, for example, HIV-1. This abstract is intended as a scanning tool for purposes of searching in the part...  
WO/2019/118851A1
Disclosed herein are protein-targeting chimeric molecules (PROTACs) that recruit a specific ubiquitin ligase, such as CRL4DCAFL\ to a chosen target protein, causing its degradation. Also disclosed herein are compositions and methods of u...  
WO/2019/116256A1
A compound of formula (I) wherein R1, R2, R3, R4 χ γ anc| A are as defined herein. The compounds of the present invention are inhibitors of hematopoietic prostaglandin D synthase (H-PGDS) and can be useful in the treatment of Duchenne ...  
WO/2019/115292A1
The present invention relates to 2-oxo-1-pyrrolidinyl imidazothiadiazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals. (I)  
WO/2019/113173A1
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, thereof: (I) which inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV life cycle of the hepa...  
WO/2019/110398A1
The invention relates to 3-amino-[1,2,4]-triazole derivatives of general formula (I) and the agrochemically compatible salts (I) thereof, and to the use thereof for controlling undesired plant growth.  
WO/2019/110006A1
Disclosed are a compound represented by the general formula (I), or a stereisomer, a tautomer, a derivative, a prodrug or a pharmaceutically acceptable salt thereof, and a method for preparing the compound and the use of the compound in ...  
WO/2019/106004A1
The invention concerns compounds having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns pharmaceutical compositions comprising t...  
WO/2019/105887A1
The invention relates to the technical field of herbicides and/or plant growth regulators. Specifically, the invention relates to isothiazolo-azepinone bicycles of formula (Gl), and compositions comprising said novel isothiazolo-azepinon...  
WO/2019/107412A1
The present invention pertains to a solid dispersion containing a compound represented by general formula (I) (wherein R1 represents an unsubstituted phenyl group or a phenyl group substituted with a substituent; the substituent represen...  
WO/2019/108591A1
The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof (1) wherein each of R1, R2, R3, R4, L1, and L2, are as defined herein. The present invention also contempl...  
WO/2019/106693A1
The compounds of Formula I and Formula (B) are described herein along with their stereoisomers, pharmaceutically acceptable salts, complexes, hydrates, solvates, tautomers, polymorphs, racemic mixtures, optically active forms, and pharma...  
WO/2019/107987A1
The present invention relates to a compound, 4-amino-N-(1-((3-chloro-2-fluoro-4-hydroxyphenyl)amino)-6-me thylisoquinolin-5-yl)thieno[3,2-d]pyrimidine-7-carboxamide, and pharmaceutically acceptable salts thereof having inhibitory activit...  
WO/2019/101551A1
The present invention relates to phenylethers of formula (I) or their agriculturally acceptable salts or derivatives, wherein the variables are defined according to the description, processes and intermediates for preparing the phenyleth...  
WO/2019/101132A1
Disclosed in the present invention are a fluorosulfonyl-containing compound, an intermediate thereof, a preparation method therefor and use thereof. The fluorosulfonyl-containing compound disclosed in the present invention comprises a ca...  
WO/2019/100914A1
Disclosed are a spherical organic photoelectric material and method for fabrication thereof and application thereof; said material has a non-conjugated spherical shape; the left and right edges are donor units, and the middle is a recept...  
WO/2019/099336A1
Disclosed are compounds of Formula (I) or salts thereof, wherein Ring Het, R1, R2, R3, R4, R5, m, n, and p are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or...  
WO/2019/095116A1
The invention relates to the technical field of polyurethane polymeric materials, and particularly to induced light-emitting polyurethane and a preparation method of the induced light-emitting polyurethane. The polyurethane takes a hydro...  
WO/2019/096911A1
The present invention relates to macrocyclic indole derivatives of general formula (I), in which R1, R2, R3, R4, R5, R6, A and L are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said...  
WO/2019/086141A1
The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV rep...  
WO/2019/090076A1
Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.  
WO/2019/085978A1
The present invention relates to heteroaryl amide compounds, a preparation method therefor, pharmaceutical compositions thereof and applications thereof, and specifically, relates to a type of compounds having broad-spectrum tumor resist...  
WO/2019/089580A1
The present invention provides methods of treating hematological disorders and solid malignant tumors, using substituted indazole compounds and pharmaceutically acceptable salts thereof. The compounds inhibit IRAK4 and BCL-2 kinases.  
WO/2019/089422A1
Compounds of Formula I as IRAK4 inhibitors are disclosed. The pharmaceutical compositions comprising compounds of formula I, methods of synthesis of these compounds, methods of treatment for diseases associated with IRAK-4 such as inflam...  
WO/2019/082808A1
This pest control agent contains, as an active ingredient, a compound represented by formula (I) or a salt thereof, and at least one selected from the group consisting of the compound and a salt thereof. In formula (I), Ar represents a p...  
WO/2019/080941A1
This invention relates to certain novel tricyclic compounds as bromodomain and extra-terminal (BET) inhibitors, their synthesis and their use for treating diseases. More particularly, this invention is directed to fused heterocyclic deri...  
WO/2019/076343A1
Disclosed are a PD-1/PD-L1 small-molecule inhibitor and a preparation method therefor and use thereof. In particular, disclosed are a compound which has a structure as shown in formula L, a stereoisomer or a tautomer thereof, or a pharma...  
WO/2019/074007A1
A polymerizable liquid crystal compound which is represented by general formula (1). (In general formula (1), the symbols are as defined in the description.)  
WO/2019/072906A1
The invention relates to compounds of formula (I): wherein the variables are defined in the specification. The invention also relates to a pesticidal mixture comprising a compound of formula (I), and another agrochemically active ingredi...  

Matches 1 - 50 out of 9,710