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Matches 551 - 600 out of 1,815

Document Document Title
WO/1993/011801A1
Complexes of bicyclopolyazamacrocyclophosphonic acid compounds with a metal ion, e.g. 153Sm, 177Lu, 159Gd, 149Pm, 140La, 175Yb, 166Ho, 90Y, 47Sc, 186Re, 188Re, 142Pr, 99mTc, 67Ga, 68Ga, 105Rh, 97Ru, 111In, 113mIn or 115mIn ion, are discl...  
WO/1993/012256A1
This invention relates to a new electrochemiluminescent (ECL) label for oligonucleotides using phosphoramidite chemistry.  
WO/1993/011800A1
Complexes of bicyclopolyazamacrocyclocarboxylic acid with Gd, Mn or Fe ions are disclosed. The complexes can be covalently attached to a biologically active molecule, e.g. an antibody or antibody fragment, to form conjugates. The complex...  
WO/1993/010747A2
The invention relates to radiolabeled imaging of a mammalian body. The invention in particular provides for reagents labeled with technetium-99m for such imaging. The invention provides peptides which bind Tc-99m and which can be targete...  
WO/1993/010822A1
Disclosed are cationic complexes of Tc-99m and ligands having structure (A), wherein: R1 is hydrogen or is selected from the group consisting of C1 to C20 alkyl; C3 to C12 cycloalkyl; C7 to C24 aralkyl; C2 to C16 alkyl ethers, thioethers...  
WO/1993/010823A1
The present invention relates particularly to novel aminothiol ligands that are suitable for complexing with a radionuclide, and are useful as general imaging agents for diagnostic purposes.  
WO/1993/008839A1
A class of diagnostic and therapeutic compounds derived from phosphinimines that include ligands containing either a single phosphinimine functionality or both a phosphinimine group and a phosphine or arsine group, or an aminato group, o...  
WO/1993/003838A1
Chiral catalysts for enantioselectively epoxidizing a prochiral olefin and for enantioselectively oxidizing a prochiral sulfide are disclosed, together with methods of using such catalysts. In accordance with one aspect of the invention,...  
WO/1993/003351A1
The present invention relates to the preparation of amino acid containing compounds which also have multiple carboxylic acid functional groups. Paramagnetic metal (II) or (III) ion chelate complexes are formed using these compounds for u...  
WO/1993/001839A1
A radiopharmaceutical product having in particular a cerebral tropism comprising a transition metal nitride complex, and a preparation method therefor, are provided. Said complex has formula (I): (M N)L1L2, wherein M is a transition meta...  
WO/1993/002090A1
The present invention is directed to low molecular weight mimics of superoxide dismutase (SOD) represented by formula (I), wherein R, R', R¿1?, R'¿1?, R¿2?, R'¿2?, R¿3?, R'¿3?, R¿4?, R'¿4?, R¿5?, R'¿5?, R¿6?, R'¿6?, R¿7?, R'...  
WO/1993/001813A1
Indole compounds substituted at the 3-position by a 7-carbonyl(pyridin-3-yl)pyrrolo[1,2-c]thiazole, 7-carbonyl(pyridin-3-yl)pyrrolo[1,2-c]oxazoline, or 7-carbonyl(pyridin-3-yl)pyrrolo[1,2-c]pyrrole group are potent antagonists of PAF and...  
WO1992019573A3  
WO/1992/021017A1
Novel complexes of paramagnetic ions and compounds bearing long acyl chains have been synthesized as magnetic resonance imaging contrast agents. These novel liposoluble contrast agents may be administered alone, or with lipids, suspendin...  
WO/1992/019235A2
A compound and method of making a compound for use as a diagnostic or therapeutic pharmaceutical comprises either a phosphorous or germanium core and at least two hydrazine groups forming a ligand for bonding to a metal extending from th...  
WO/1992/019573A2
A compound and method of making a compound for use as a diagnostic or therapeutic pharmaceutical comprises either a phosphorous or germanium core and at least two hydrazine groups forming a ligand for bonding to a metal extending from th...  
WO/1992/019274A1
The invention relates to a technetium chelate of general formula (I), wherein X is a sulphur atom or an imino group, Z is a hydrogen atom, a carboxy group, an alkoxycarbonyl group having 1-4 carbon atoms, an aminocarbonyl group, a sulpho...  
WO/1992/014492A1
The present invention relates to a process of making radiopharmaceuticals in situ, i.e. wherein a radionuclide and an acyclic ligand react with constituents of the complex forming reaction solution to produce an administratable radiophar...  
WO1992007860A3  
WO/1992/010465A1
The present invention relates particularly to novel preorganized hexadentate ligands that are suitable for complexing with a radionuclide, and are useful as general imaging agents for diagnostic purposes.  
WO/1992/010466A1
The present invention relates particularly to novel preorganized hexadentate ligands that are suitable for complexing with a radionuclide, and are useful as general imaging agents for diagnostic purposes. They have general formula (I), w...  
WO/1992/010460A1
The present invention relates to a process for preparing platinum group metal and rhenium salts of organic carboxylic acids and products obtained using the disclosed process. The process comprises reacting an alkali or alkaline earth met...  
WO/1992/007859A1
The present invention relates to novel technetium-99m complexes and to methods of preparing the complexes. The present invention further relates to radiopharmaceutical compositions comprising the complexes, to the use of the compositions...  
WO/1992/007860A2
The present invention relates to novel technetium-99m complexes and to methods of preparing the complexes. The present invention further relates to a radiopharmaceutical composition comprising the complexes, to the use of the composition...  
WO/1992/005154A1
The present invention relates particularly to novel aminothiol ligands that are suitable for complexing with a radionuclide, and are useful as general imaging agents for diagnostic purposes.  
WO/1992/000982A1
Process for the preparation of transition metal nitrido complexes for use as radiopharmaceutical products or for the synthesis of novel pharmaceutical products. The process consists in reacting an oxygenic transition metal compound such ...  
WO1991010645A3  
WO/1991/019516A1
The invention relates to a metal-radionuclide complex comprising isonitrile ligands, said complex having general formula (I), wherein M is a metal-radionuclide selected from radioisotopes of Tc, Ru, Fe, Cr, Mn, Cu, Pb, Ga, As and In; R1 ...  
WO/1991/018908A1
The invention concerns ?99m�Tc cyclopentadienyl carbonyl complexes of general formula (I), in which -XR can have various meanings. These new technetium-99m complexes can be used in the field of medical diagnosis. The invention also con...  
WO/1991/017999A1
The invention relates to a method for labelling substances, including cells such as blood cells, which contain one or more amino groups, with a radioisotope, the substance to be labelled being combined in the presence of a reductor with ...  
WO1991015466A3  
WO/1991/016076A1
The invention relates to a method of preparing a radiolabeled technetium complex by bringing together a pertechnetate solution in a complex-forming reaction with a compound of general formula (I) wherein R1-R12 independently represent H,...  
WO/1991/015466A2
Chelants of formula (I) (as given in claim 1) are disclosed. The chelants are of particular use in producing therapeutic, diagnostic and detoxification agents.  
WO/1991/015467A1
Aminopolycarboxylic acid chelating agents and the metal chelates thereof, which may be useful in producing agents for radiotherapy, diagnostic imaging or heavy metal detoxification are described.  
WO/1991/014685A1
Technetium-99m complexes of crown thioethers having 3 to 6 donor sulphur atoms joined into a macrocyclic ring by C2 or C3 groups, for example 1,4,7-trithiacyclononane (9S3); and of tripodal ligands having more than 3 donor sulphur atoms ...  
WO/1991/014694A1
Chiral catalysts for enantioselectively epoxidizing a prochiral olefin are disclosed, together with methods of using such catalysts. In accordance with one aspect of the invention, the catalyst is a salen derivative which has general str...  
WO/1991/012822A1
Preparations for MR diagnosis containing complexes of compounds of general formula (I), where R1 stands for hydrogen and C1-C4 alkyl, R2 stands for -PO(OH)2, -OPO(OH)2 and -SO3H and X is a single bond and -(CH2)n, where n stands for 1 an...  
WO1990014106A3  
WO/1991/010645A2
There are provided novel chelating agents useful in the preparation of contrast media for diagnostic imaging or of radiotherapeutic or detoxification compositions.  
WO/1991/009825A1
The invention pertains to rhenium (VII) compounds which are catalysts for metathesis of ordinary olefins (hydrocarbons) and functionalized olefins in a homogeneous phase and to methods of synthesizing these compounds. The rhenium compoun...  
WO/1991/003261A1
Novel magnetic resonance imaging agents comprise complexes of paramagnetic ions with aminoalkylamide derivatives of diethylenetriaminepentaacetic acid (''DTPA'') or ethylenediaminetetraacetic acid (''EDTA'') or other polyaminocarboxylic ...  
WO/1991/003262A1
Novel complexes of technetium (99Tc or 99mTc) which contain the moiety Tc=NR, Tc-N=NY or Tc(-N=NY)2, and a ligand which confers biological target-seeking properties on the complex, wherein R represents an aryl group, a substituted or uns...  
WO/1991/001806A1
Novel oxidation catalysts of functional organic compounds consisting of synthetic metalloporphyrins fixed on a substrate. These novel catalysts involve the use of polymer-type substrates which are insoluble in the liquid phase comprising...  
WO1990014881A3  
WO/1990/015808A1
Chelating compounds of specified structure are useful for radiolabeling targeting proteins such as antibodies. The radiolabeled antibodies, or catabolites thereof, demonstrate improved biodistribution properties, including reduced locali...  
WO/1990/014881A2
A new series of bifunctional chelating agents useful for attaching metal ions to proteins, polypeptides and other polymers and methods for their preparation are described. These reagents are unique in their ability to bind a variety of m...  
WO/1990/014106A2
A myocardial imaging agent for humans is a technetium(III) complex ligated in the planar positions by a tetradentate ligand such as (acac)2en and in the axial positions by an ether containing phosphine ligand such as tris(3-methoxy-1-pro...  
WO/1990/013530A1
The process of the present invention includes preparing a first aqueous solution of rhenium in the form of radioactive perrhenate, wherein the concentration of rhenium in said solution is within the range of about 5 x 10-6 M to about 2 x...  
WO/1990/010633A1
The present invention involves a novel tripyrroledimethine-derived "expanded porphyrin" (texaphyrin), the synthesis of such compounds, their analogs or derivatives and their uses. These expanded porphyrin-like macrocycles are efficient c...  
WO/1990/009987A1
Polynitrogenous derivatives comprising four or five coordinating functions capable of bonding with a metal atom, especially with cobalt. The invention concerns, more particularly, the use of metal complexes comprising said derivatives fo...  

Matches 551 - 600 out of 1,815