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Matches 551 - 600 out of 1,794

Document Document Title
WO/1993/001839A1
A radiopharmaceutical product having in particular a cerebral tropism comprising a transition metal nitride complex, and a preparation method therefor, are provided. Said complex has formula (I): (M N)L1L2, wherein M is a transition meta...  
WO/1993/002090A1
The present invention is directed to low molecular weight mimics of superoxide dismutase (SOD) represented by formula (I), wherein R, R', R¿1?, R'¿1?, R¿2?, R'¿2?, R¿3?, R'¿3?, R¿4?, R'¿4?, R¿5?, R'¿5?, R¿6?, R'¿6?, R¿7?, R'...  
WO/1993/001813A1
Indole compounds substituted at the 3-position by a 7-carbonyl(pyridin-3-yl)pyrrolo[1,2-c]thiazole, 7-carbonyl(pyridin-3-yl)pyrrolo[1,2-c]oxazoline, or 7-carbonyl(pyridin-3-yl)pyrrolo[1,2-c]pyrrole group are potent antagonists of PAF and...  
WO1992019573A3  
WO/1992/021017A1
Novel complexes of paramagnetic ions and compounds bearing long acyl chains have been synthesized as magnetic resonance imaging contrast agents. These novel liposoluble contrast agents may be administered alone, or with lipids, suspendin...  
WO/1992/019235A2
A compound and method of making a compound for use as a diagnostic or therapeutic pharmaceutical comprises either a phosphorous or germanium core and at least two hydrazine groups forming a ligand for bonding to a metal extending from th...  
WO/1992/019573A2
A compound and method of making a compound for use as a diagnostic or therapeutic pharmaceutical comprises either a phosphorous or germanium core and at least two hydrazine groups forming a ligand for bonding to a metal extending from th...  
WO/1992/019274A1
The invention relates to a technetium chelate of general formula (I), wherein X is a sulphur atom or an imino group, Z is a hydrogen atom, a carboxy group, an alkoxycarbonyl group having 1-4 carbon atoms, an aminocarbonyl group, a sulpho...  
WO/1992/014492A1
The present invention relates to a process of making radiopharmaceuticals in situ, i.e. wherein a radionuclide and an acyclic ligand react with constituents of the complex forming reaction solution to produce an administratable radiophar...  
WO1992007860A3  
WO/1992/010465A1
The present invention relates particularly to novel preorganized hexadentate ligands that are suitable for complexing with a radionuclide, and are useful as general imaging agents for diagnostic purposes.  
WO/1992/010466A1
The present invention relates particularly to novel preorganized hexadentate ligands that are suitable for complexing with a radionuclide, and are useful as general imaging agents for diagnostic purposes. They have general formula (I), w...  
WO/1992/010460A1
The present invention relates to a process for preparing platinum group metal and rhenium salts of organic carboxylic acids and products obtained using the disclosed process. The process comprises reacting an alkali or alkaline earth met...  
WO/1992/007859A1
The present invention relates to novel technetium-99m complexes and to methods of preparing the complexes. The present invention further relates to radiopharmaceutical compositions comprising the complexes, to the use of the compositions...  
WO/1992/007860A2
The present invention relates to novel technetium-99m complexes and to methods of preparing the complexes. The present invention further relates to a radiopharmaceutical composition comprising the complexes, to the use of the composition...  
WO/1992/005154A1
The present invention relates particularly to novel aminothiol ligands that are suitable for complexing with a radionuclide, and are useful as general imaging agents for diagnostic purposes.  
WO/1992/000982A1
Process for the preparation of transition metal nitrido complexes for use as radiopharmaceutical products or for the synthesis of novel pharmaceutical products. The process consists in reacting an oxygenic transition metal compound such ...  
WO1991010645A3  
WO/1991/019516A1
The invention relates to a metal-radionuclide complex comprising isonitrile ligands, said complex having general formula (I), wherein M is a metal-radionuclide selected from radioisotopes of Tc, Ru, Fe, Cr, Mn, Cu, Pb, Ga, As and In; R1 ...  
WO/1991/018908A1
The invention concerns ?99m�Tc cyclopentadienyl carbonyl complexes of general formula (I), in which -XR can have various meanings. These new technetium-99m complexes can be used in the field of medical diagnosis. The invention also con...  
WO/1991/017999A1
The invention relates to a method for labelling substances, including cells such as blood cells, which contain one or more amino groups, with a radioisotope, the substance to be labelled being combined in the presence of a reductor with ...  
WO1991015466A3  
WO/1991/016076A1
The invention relates to a method of preparing a radiolabeled technetium complex by bringing together a pertechnetate solution in a complex-forming reaction with a compound of general formula (I) wherein R1-R12 independently represent H,...  
WO/1991/015466A2
Chelants of formula (I) (as given in claim 1) are disclosed. The chelants are of particular use in producing therapeutic, diagnostic and detoxification agents.  
WO/1991/015467A1
Aminopolycarboxylic acid chelating agents and the metal chelates thereof, which may be useful in producing agents for radiotherapy, diagnostic imaging or heavy metal detoxification are described.  
WO/1991/014685A1
Technetium-99m complexes of crown thioethers having 3 to 6 donor sulphur atoms joined into a macrocyclic ring by C2 or C3 groups, for example 1,4,7-trithiacyclononane (9S3); and of tripodal ligands having more than 3 donor sulphur atoms ...  
WO/1991/014694A1
Chiral catalysts for enantioselectively epoxidizing a prochiral olefin are disclosed, together with methods of using such catalysts. In accordance with one aspect of the invention, the catalyst is a salen derivative which has general str...  
WO/1991/012822A1
Preparations for MR diagnosis containing complexes of compounds of general formula (I), where R1 stands for hydrogen and C1-C4 alkyl, R2 stands for -PO(OH)2, -OPO(OH)2 and -SO3H and X is a single bond and -(CH2)n, where n stands for 1 an...  
WO1990014106A3  
WO/1991/010645A2
There are provided novel chelating agents useful in the preparation of contrast media for diagnostic imaging or of radiotherapeutic or detoxification compositions.  
WO/1991/009825A1
The invention pertains to rhenium (VII) compounds which are catalysts for metathesis of ordinary olefins (hydrocarbons) and functionalized olefins in a homogeneous phase and to methods of synthesizing these compounds. The rhenium compoun...  
WO/1991/003261A1
Novel magnetic resonance imaging agents comprise complexes of paramagnetic ions with aminoalkylamide derivatives of diethylenetriaminepentaacetic acid (''DTPA'') or ethylenediaminetetraacetic acid (''EDTA'') or other polyaminocarboxylic ...  
WO/1991/003262A1
Novel complexes of technetium (99Tc or 99mTc) which contain the moiety Tc=NR, Tc-N=NY or Tc(-N=NY)2, and a ligand which confers biological target-seeking properties on the complex, wherein R represents an aryl group, a substituted or uns...  
WO/1991/001806A1
Novel oxidation catalysts of functional organic compounds consisting of synthetic metalloporphyrins fixed on a substrate. These novel catalysts involve the use of polymer-type substrates which are insoluble in the liquid phase comprising...  
WO1990014881A3  
WO/1990/015808A1
Chelating compounds of specified structure are useful for radiolabeling targeting proteins such as antibodies. The radiolabeled antibodies, or catabolites thereof, demonstrate improved biodistribution properties, including reduced locali...  
WO/1990/014881A2
A new series of bifunctional chelating agents useful for attaching metal ions to proteins, polypeptides and other polymers and methods for their preparation are described. These reagents are unique in their ability to bind a variety of m...  
WO/1990/014106A2
A myocardial imaging agent for humans is a technetium(III) complex ligated in the planar positions by a tetradentate ligand such as (acac)2en and in the axial positions by an ether containing phosphine ligand such as tris(3-methoxy-1-pro...  
WO/1990/013530A1
The process of the present invention includes preparing a first aqueous solution of rhenium in the form of radioactive perrhenate, wherein the concentration of rhenium in said solution is within the range of about 5 x 10-6 M to about 2 x...  
WO/1990/010633A1
The present invention involves a novel tripyrroledimethine-derived "expanded porphyrin" (texaphyrin), the synthesis of such compounds, their analogs or derivatives and their uses. These expanded porphyrin-like macrocycles are efficient c...  
WO/1990/009987A1
Polynitrogenous derivatives comprising four or five coordinating functions capable of bonding with a metal atom, especially with cobalt. The invention concerns, more particularly, the use of metal complexes comprising said derivatives fo...  
WO/1990/008138A1
There are provided heterocyclic chelating agents particularly useful for the preparation of diagnostic and therapeutic agents for magnetic resonance imaging, scintigraphy, ultrasound imaging, radiotherapy and heavy metal detoxification, ...  
WO/1990/007342A1
The present invention is directed to a novel process for preparing isothiocyanate functionalized chelates by reacting amino functionalized chelates with thiophosgene.  
WO/1990/006137A1
The invention concerns a radiopharmaceutical product having, in particular, a cardiac tropism, comprising a nitruro complex of a transition metal, and process for preparation thereof. The complex has the formula (M=N)L1L2 in which M is a...  
WO/1990/005733A1
The present invention relates to a technetium-99m complex of general formula (I), wherein Z is a sulphur atom or an amino group of the general formula R17-N-(R18)k, in which k is 0 or 1 and R17 and R18 have the same meanings as the symbo...  
WO/1990/003975A1
A process is provided for the preparation of Mn(II) chelates for use as contrast agents in magnetic resonance imaging, said process comprising reacting insoluble manganese (II) oxide with an aqueous suspension comprising a molar equivale...  
WO1989011877A3  
WO/1990/001024A1
Novel magnetic resonance imaging agents comprise complexes of paramagnetic ions with alkoxyalkylamide derivatives of diethylenetriaminepentaacetic acid (''DTPA'') or ethylenediaminetetyraacetic acid (''EDTA''). These novel imaging agents...  
WO/1990/000854A1
Complexes useful as radiopharmaceutical imaging agents comprise technetium bonded to a ligand which generally can be described by formula (I), wherein Z is N, C, B or P; the three Y groups can be the same or different, each characterized...  
WO1989012058A3  

Matches 551 - 600 out of 1,794