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Matches 1 - 50 out of 1,813

Document Document Title
WO/2020/179420A1
Provided is a novel compound capable of efficiently introducing CO into cells. The novel compound is represented by formula (A). In the formula, R represents hydrogen or an alkyl group which has 1-8 carbon atoms and optionally has a subs...  
WO/2020/144476A1
The invention provides a method comprising hydrogenating a ketone in the presence of (i) a base, (ii) hydrogen gas and (iii) a catalyst comprising a charged or neutral complex of formula (I): (I) wherein: Mn is a manganese atom or a mang...  
WO/2020/094789A1
Inventors have shown that sub-lethal concentrations of H2O2-exposure initiated a DNA damage response illustrated by increased ϒH2AX and 53BP1 expression and foci formation mainly in sensory hair cells, together with increased levels of ...  
WO/2020/088187A1
Disclosed are a novel organometallic complex, an organic electronic device thereof and the uses thereof, particularly in organic phosphorus light emitting diodes. Also disclosed are an electronic device thereof containing the organometal...  
WO/2020/074142A1
Catechol metal complex compounds of formula (I), wherein R1 and R2 independently of one another represent a hydrocarbon radical having 1 to 20 carbon atoms which is optionally substituted with at least one radical selected from hydroxyl,...  
WO/2020/034164A1
Through the use of a rhodamine appended chelate, a versatile strategy has been demonstrated to generate mitochondria-targeting photosensitizers via the incorporation of variety of luminescent transition metal systems. The generation of t...  
WO/2020/037166A1
A composition comprising the following structure: (1) wherein Re represents a rhenium ion having a +1 charge; (I) represents an uncharged bidentate ligand containing at least one ring containing a ring nitrogen atom bound to the rhenium ...  
WO/2019/218275A1
Disclosed are a polyacid hybrid compound guided by metal ions and functionalized by a carboxylate ligand, a preparation method therefor and the use thereof in the catalytic degradation of chemical warfare agent simulants. In the method, ...  
WO/2019/177449A1
The invention relates to a new lutetium-177 therapeutic radiopharmaceutical as an inhibitor of prostate-specific membrane antigen (iPSMA), wherein 1,4,7,10-tetraazacyclododecane-N,N´,N´´,N´´´´-tetraac etic acid (DOTA) bonded to th...  
WO/2019/123409A1
Multinuclear complexes and methods for preparing them are provided. The discrete multinuclear complexes include a one or more transition metals and a radioisotope having the same coordination geometry as the transition metal. A bridging ...  
WO/2019/097101A1
The present invention describes a new method for functionalising proteins by incorporating a metal fragment of high-performance rhenium, thus producing coordinated iminopyridines having three carbonyl groups in the fac position which pro...  
WO/2019/091898A1
The present invention relates to a process for preparing 5-substituted imidazole compounds of formula (I), by reacting a ketone of formula (II) (II), and a manganese compound of formula (III), (III), wherein R1, R2, R3, R4, R5, Q, X, Y, ...  
WO/2019/039509A1
A composition comprising: a substance (A) (excluding a metal-organic framework) comprising atoms of at least one metal selected from the group consisting of zinc, cobalt, niobium, zirconium, cadmium, copper, nickel, chromium, vanadium, t...  
WO/2019/027059A1
The purpose of the present invention is to produce a radiolabeled aryl compound by a simple method in which labeling can be carried out in a short time in high radiochemical yield and which renders the radiolabeled aryl compound usable i...  
WO/2019/007664A1
The invention relates to an N-heterocyclic carbene (NHC) Re(I) complex having an unsubstituted or substituted benzimidazol-2-ylidene ligand and the use thereof, in particular in a pharmaceutical composition, as a medication and for treat...  
WO/2018/227977A1
Disclosed are a 99mTc-labelled isonitrile-containing glucose derivative of the structural general formula [99mTc-(CNDG)6]+ and a preparation method and the use. The derivative takes 99mTc+ as a central core, and the isonitrile carbon ato...  
WO/2018/225466A1
Provided are: a curing accelerator for an oxidatively polymerized unsaturated resin, having high curing acceleration characteristics; and a printing ink and paint using same. Specifically, provided are: a curing accelerator for an oxidat...  
WO/2018/192686A1
The invention relates to a method for producing, amongst other things, amino-acid and/or hydroxycarboxylic-acid metal chelates, a solvent-free mixture of at least one metal oxide, metal hydroxide, metal carbonate or oxalate, and the soli...  
WO/2018/189060A1
The invention comprises novel chiral metal complex compounds of the formula (I) wherein M, PR2, R3 and R4 are outlined in the description, its stereoisomers, in the form as a neutral complex or a complex cation with a suitable counter io...  
WO/2018/170553A1
This invention provides rhenium tricarbonyl complexes and their use in the treatment of cancer and inhibition of Aurora kinase. The rhenium tricarbonyl complexes comprise a C-donor N-heterocyclic carbene (NHC) ligand. Also provided are p...  
WO/2018/153333A1
The present invention provides a biflavonoid-manganese complex and a preparation method and application thereof. The present invention uses amentoflavone as a ligand and a manganese ion as a central ion for reaction to obtain an amentofl...  
WO/2018/121465A1
Diphosphino metallic complexes, methods of making and using are described. The complexes display cytotoxicity against a panel of cancer cell lines, and optionally display luminescent properties. They have improved solubility and are stab...  
WO/2018/115314A1
The invention provides compounds of formula (I) representing a polyaza-macrocycle with carboxylic acid side arms complexing Manganese as core metal. The complexes are suitable for use as contrast agents in magnetic resonance imaging (MRI).  
WO/2018/107526A1
The invention provides a method for preparing a tricarbonyl technetium-99m intermediate. The method comprises reacting a carbonyl manganese compound used as a carbon monoxide donor with pertechnetate and water to obtain the tricarbonyl t...  
WO/2018/109164A1
The present invention relates to a labeling procedure for the incorporation, in mild reaction conditions, of sensitive and thermosensitive targeting molecules into a [99m Tc(N)(PNP)]-based compound suitable for a kit formulation.  
WO/2017/050970A8
The present invention relates to highly efficient Nrf2 activators-CO-releasing molecules of formula (I) and (II) capable of increasing HO-1 protein expression and simultaneously releasing CO, their synthesis and their use in therapeutic ...  
WO/2018/046391A1
Metal complexes containing substituted allyl ligands and methods of using such metal complexes to prepare metal-containing films are provided.  
WO/2018/028312A1
A method of preparing luminescent nano-sheets includes preparing a precursor emulsion solution containing a metal halide and RNH 3X, with the molar ratio of metal halide to RNH 3X in a range of approximately 0.6 to approximately 0.8; dem...  
WO/2018/000984A1
A manganese (II) complex, a preparation method therefor and an application thereof, a structure of the complex being: (R1 R2 R 3 R4 A)2[MnX4], wherein, R1, R2, R3 and R4 are identical or different, and are independently selected from alk...  
WO/2017/223428A1
A composition comprising the following structure: (formula I) wherein Re represents a rhenium ion having a +1 charge; (formula II) represents an uncharged bidentate bicyclic ligand bonded to the rhenium (Re) by two ring nitrogen (N) atom...  
WO/2017/222362A1
The invention relates to a novel radiopharmaceutical that inhibits the prostate-specific membrane antigen (iPSMA), containing hydrazinonicotinamide (HYNIC) as a critical chemical group in increasing in the lipophilicity of the molecule f...  
WO/2017/180136A1
Provided herein are cross-linked graphene platelet polymers, compositions thereof, filtration devices comprising the cross-linked graphene platelet polymers and/or compositions thereof and method is using and making the same.  
WO/2017/137984A1
The present invention relates to novel manganese complexes and their use, inter alia, for homogeneous catalysis in (1) the preparation of imine by dehydrogenative coupling of an alcohol and amine; (2) C-C coupling in Michael addition rea...  
WO/2017/093283A1
The present invention is in the field of processes for the generation of thin inorganic films on substrates, in particular atomic layer deposition processes. The present invention relates to a process comprising bringing a compound of ge...  
WO/2017/089230A1
The present invention is in the field of processes for the generation of thin inorganic films on substrates, in particular atomic layer deposition processes. The present invention relates to a process comprising bringing a compound of ge...  
WO/2017/031173A8
Disclosed herein are novel amine-functionalized porphyrin compounds, as wells as pharmaceutically acceptable salts or esters thereof. The disclosed compounds can be used to impart antioxidant, antiinflammatory, anti-microbial, and/or cel...  
WO/2017/059130A2
The disclosure provides for diamine-appended metal-organic frameworks (MOFs), methods of making thereof, and methods of use thereof.  
WO/2017/027728A9
Aspects of the present disclosure relate to compounds which have enhanced oral bioavailability. A transition metal complex includes a transition metal coordinated by a macrocycle comprising the pentaaza 15-membered macrocyclic ring corre...  
WO/2017/050970A1
The present invention relates to highly efficient Nrf2 activators-CO-releasing molecules of formula (I) and (II) capable of increasing HO-1 protein expression and simultaneously releasing CO, their synthesis and their use in therapeutic ...  
WO/2017/031173A1
Disclosed herein are novel amine-functionalized porphyrin compounds, as wells as pharmaceutically acceptable salts or esters thereof. The disclosed compounds can be used to impart antioxidant, antiinflammatory, anti-microbial, and/or cel...  
WO/2017/027834A1
Provided herein are examples of metal chelating ligands that have high affinity for manganese. The resultant metal complexes can be used as MRI contrast agents, and can be functionalized with moieties that bind to or cause relaxivity cha...  
WO/2017/027728A1
Aspects of the present disclosure relate to compounds which have enhanced oral bioavailability. A transition metal complex includes a transition metal coordinated by a macrocycle comprising the pentaaza 15-membered macrocyclic ring corre...  
WO/2017/015722A1
The present disclosure relates to complexes for intracellular imaging and also to methods and kits for intracellular imaging or cell labelling. Certain embodiments of the present disclosure provide a complex comprising a transition metal...  
WO/2017/005822A1
The present invention relates to a X-ray fluorescence molecular probe of formula I or a salt thereof, wherein X, Het 1, R1, Y1, Y2, L and R2 are as defined in the claims. The invention also relates to the use of the probes of the inventi...  
WO/2016/191424A3
The present invention includes novel compounds and compositions including heteroaromatic Silicon-Fluoride- Acceptors, which are useful for PET scanning. The present invention further includes a novel method of 18F imaging for PET scannin...  
WO/2016/203887A1
This novel compound is characterized by being represented by general formula (I) or (II). [In the formula, R1 and R2 each independently represent a hydrocarbon group having 1 to 12 carbon atoms, and a hydrogen atom in the hydrocarbon gro...  
WO/2016/205113A1
A number of new classes of polymers with the potential for electrical conduction are introduced sharing a common theme, having metal atoms in direct contact with each other, bound in one and two-dimensional structures guided by steric, d...  
WO/2016/189109A1
The present invention relates to a polyoxomolybdate-bisphosphonate complex containing a bisphosphonate ligand, wherein it further contains a heterometallic ion different from molybdenum, for use in treating cancer. It further relates to ...  
WO/2016/191424A2
The present invention includes novel compounds and compositions including heteroaromatic Silicon-Fluoride- Acceptors, which are useful for PET scanning. The present invention further includes a novel method of 18F imaging for PET scannin...  
WO/2016/181918A1
The present invention relates to a chemical vapor deposition starting material represented below that comprises a heterogeneous polynuclear complex in which cyclopentadienyl and a carbonyl are coordinated to a first transition metal and ...  

Matches 1 - 50 out of 1,813