Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 1 - 50 out of 8,852

Document Document Title
WO/2018/013655A1
Solid state forms of Crisaborole and salts thereof, processes for preparation thereof and pharmaceutical compositions thereof are disclosed.  
WO/2018/013682A1
Covalent organic frameworks (COFs) usually crystallize as insoluble powders and their processing for suitable devices has been thought to be limited. Here, it is demonstrated that COFs can be mechanically pressed into shaped objects havi...  
WO/2018/000402A1
An application of a bis(β-diimide) rare earth amide for catalyzing a hydroboration reaction between a ketone and a borane. The molecular formula of a catalyst is [2‑Me‑C6H4‑NC(Me)CHC(Me)N‑C6H4‑2‑Me]2LnN(SiMe3)2 , wherein Ln ...  
WO/2018/000401A1
An application of a trisilicon amine rare earth complex for catalyzing hydroboration reaction between an aldehyde and a borane. The trisilicon amine complex La[N(SiMe3)2]3 can provide, under mild conditions, a highly catalytic effect for...  
WO/2018/005732A1
Provided herein are curcumin analogues that are able to interact with amyloid beta (Aβ) and to attenuate the copper-induced crosslinking of Aβ. Also provided herein are methods of using the compounds as imaging agents of amyloid beta a...  
WO/2018/003470A1
Because a sulfonium salt that does not contain a toxic metal and that exhibits polymerization performance and crosslinking reaction performance equal to or greater than those of a tetrakis (pentafluorophenyl) borate salt, a photoacid gen...  
WO/2018/005662A1
Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the method of use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents, for example, β-l...  
WO/2018/000400A1
Provided is an application of a β-diimide bivalent rare earth borohydride complex for catalyzing a hydroboration reaction between a borane and a ketone. A β-diimide rare earth dichloride is reacted with NaBH4 in a tetrahydrofuran solut...  
WO/2017/222819A2
The present disclosure encompasses solid state forms of Ixazomib Citrate and pharmaceutical compositions thereof. Also disclosed are processes for preparation of Ixazomib Citrate.  
WO/2017/220660A1
The present invention relates to a compound comprising at least one phosphepine ring and having the phosphorus atom of the phosphepine ring substituted with at least one monovalent substituent R, a semiconducting material comprising the ...  
WO/2017/223406A1
Disclosed herein are borazine complexes and use of the same in perfluoroalkylation reactions.  
WO/2017/218460A1
Metal coordination complexes comprising a metal atom coordinated to at least one aza-allyl ligand having the structure represented by formula (I) where each R1-R4 are independently selected from the group consisting of H, branched or unb...  
WO/2017/216816A1
The present invention is directed to a novel tumor-selective boron- comprising compound and to pharmaceutical compositions comprising such compound. The invention also regards such compound for medical use in diagnosis and/or treating tu...  
WO/2017/207913A1
The invention relates to functionalised dioxaborolane or dioxaborinane derivatives of formula (I), wherein R1 is covalently bonded to the boron atom by a carbon atom; one of R2 , R3 ,R'3 or R4 is a radical of formula –X; or one of R1 ,...  
WO/2017/208258A1
The present invention discloses a novel process for the preparation of gadolinium complex of (4S)-4-(4-Ethoxybenzyl)-3,6,9-tris(carboxylatomethyl)-3,6,9- triazaundecanedioic acid disodium of formula 1 and novel intermediates thereof.  
WO/2017/207358A1
The present invention relates to the use of the compounds of formula (I) wherein the variables are defined according to the description, for controlling unwanted vegetation Further the invention relates to novel compounds of the formula ...  
WO/2017/207534A1
The present invention covers substituted heteroarylbenzimidazole compounds of general formula (I) : in which R1, R2, R3, R4, R5, R6a and R6b are as defined herein, methods of preparing said compounds, intermediate compounds useful for pr...  
WO/2017/202701A1
Process to prepare alkylaluminoxane by reacting, in the absence of solvent, 1 molar equivalent of alkylaluminium with 0.1 to 0.8 molar equivalent of a substituted allylic alcohol of the formula (I) wherein R1 and R2 are independently sel...  
WO/2017/202379A1
A water soluble, simple, stable tris(N-(tert-butyl) acetamide) cyclen-based europium complex HGEU001 which exhibits the specific subcellular localization in the primary cilium with a quantum yield as high as 10% in water and a lifetime o...  
WO/2017/203514A9
Provided are crisaborole polymorphs, e.g., crystalline Form A, crystalline Form B, crystalline Form C, crystalline Form D, crystalline Form E, crystalline Form F and processes for producing these polymorphs.  
WO/2017/203514A1
Provided are crisaborole polymorphs, e.g., crystalline Form A, crystalline Form B, crystalline Form C, crystalline Form D, crystalline Form E, crystalline Form F and processes for producing these polymorphs.  
WO/2017/199056A1
The invention relates to BODIPY derivatives of Formula (I) that bear one or more functional groups which in the photochemical reaction upon irradiation with visible light undergo deamination and deliver quinone methides. Furthermore, the...  
WO/2017/197604A1
A method for preparing a crizotinib intermediate, the method comprising: (1) synthesizing a compound 1 and a compound 2 into a compound 3 by means of flow chemical reaction; (2) synthesizing the compound 3 obtained in step (1) and a bori...  
WO/2017/198194A1
Disclosed is a compound as represented by formula (I). Also provided in the present invention are a pharmaceutically acceptable salt of the compound, a preparation method for same, uses of same, and a pharmaceutical composition thereof. ...  
WO/2017/201377A1
Improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalky and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridi ne-2-carboxylates and arylalkyl and alkyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-...  
WO/2017/199870A1
In the first aspect of the present invention, aluminum oxide is produced using an aluminum-oxide-forming agent containing: a partially hydrolyzed aluminum alkyl compound (obtained by hydrolyzing, in water having a molar ratio of 0.5–1....  
WO/2017/193914A1
The present invention relates to four crystal forms of crisaborole in free form and the preparation method thereof. The present invention also relates to the pharmaceutical composition containing the crystal forms and the use thereof.  
WO/2017/195069A1
The present invention provides oxaborole ester compounds and compositions thereof which are useful to treat diseases associated with parasites, such as Chagas Disease and African Animal Trypanosomosis.  
WO/2017/195669A1
The present invention addresses the problem of providing an organic electroluminescence element material that presents excellent performance and improves drive voltage and emission luminance, whether it is used for a host material, an el...  
WO/2017/192991A1
The present disclosure relates to orally bioavailable selective estrogen receptor down-regulators (SERDs) and the synthesis of the same. Further, the present disclosure teaches the utilization of the orally bioavailable selective estroge...  
WO/2017/191130A3
Disclosed are small molecule therapeutic compounds that are potent inhibitors of arginase 1 and arginase 2 activity. Also disclosed are pharmaceutical compositions comprising the compounds, and methods for using the compounds for treatin...  
WO/2017/191467A1
Solid-phase supported materials are described for use in supporting metallocene catalytic compounds. The supported metallocene catalytic compositions are efficient olefin polymerisation catalysts, which show notably higher catalytic acti...  
WO/2017/191795A1
The present invention is a rare-earth complex polymer including a trivalent rare-earth ion and a phosphine oxide bidentate ligand. In the present invention, a single phosphine oxide bidentate ligand is coordinated with two rare-earth ion...  
WO/2017/191130A2
Disclosed are small molecule therapeutic compounds that are potent inhibitors of arginase 1 and arginase 2 activity. Also disclosed are pharmaceutical compositions comprising the compounds, and methods for using the compounds for treatin...  
WO/2017/188485A1
Provided is a compound represented by formula (A-V), wherein Y represents a p-valent anion; R1A to R8A each independently represent a hydrogen atom or an alkyl group having 1-10 carbon atoms; R9A and R10A each independently represent a h...  
WO/2017/188111A1
Provided is an organic EL element having optimum light emission characteristics using a light-emitting layer material comprising a novel polycyclic aromatic compound (1) in which a plurality of aromatic rings are linked by a boron atom a...  
WO/2017/183043A1
The invention relates to novel process for preparation of Tavaborole. The invention also relates to novel polymorphic forms of Tavaborole and process for preparation of those polymorphic forms. The invention also relates to process for p...  
WO/2017/181791A1
Provided is an application of a compound comprising 10B for preparing a pharmaceutical product specifically binding an amyloid β-protein. After the pharmaceutical product specifically binding the amyloid β-protein binds the amyloid β-...  
WO/2017/184431A1
Complexes, compositions, articles of manufacture, and method for making the same are provided herein. In one embodiment, a borate-polyol complex may be prepared by reacting a boron-containing compound and a polyol to form a reaction mixt...  
WO/2017/181897A1
The present invention discloses a novel broad-spectrum β-lactamase inhibitor compound. The structure of the compound is represented by formula (I). An investigation studying the effects of the compound provided by the invention on the a...  
WO/2017/176085A1
The present invention relates to an aluminum precursor synthesization system and an aluminum precursor preparation method using the same and, more specifically, to a novel aluminum precursor synthesization system and an aluminum precurso...  
WO/2017/173668A1
The present invention discloses a method for preparing a phenylboronic acid neopentyl glycol ester. A mixed nickel(II) complex with a formula of Ni[P(OR1)3][(R2NCH2CH2NR2)C]X2 is used as a catalyst. The method comprises: in the presence ...  
WO/2017/174868A1
The present invention relates to a diborane-free method for producing borane complexes, such as borane dimethyl sulfide. The method includes reacting boron trifluoride and a Lewis base with a certain tertiary amines, such as 1,2,2,6,6- p...  
WO/2017/176841A1
Described herein are molecules for use in organic light emitting diodes. Example compounds include molecules represented by structural formula (I). Values and example value of in the structural formula (I) are defined herein.  
WO/2017/170976A1
The purpose of the present invention is to provide a highly practical electrolyte solution which is easily prepared and has a high oxidative decomposition potential, and wherein dissolution and precipitation of magnesium repeatedly proce...  
WO/2017/162204A1
The present invention discloses a manufacturing method of a benzofuran analog and an intermediate and crystalline form of same.  
WO/2017/164093A1
The present invention addresses the problem of providing a novel π-conjugated boron compound in which the bonding between a boron atom and a carbon atom is enhanced. The present invention also addresses the problem of providing an elect...  
WO/2017/164172A1
Provided are a compound that is bioapplicable and amyloid-selective, and is useful as an amyloid oxidation catalyst applicable not only to aβ peptides but to other amyloids as well, and a preventive/therapeutic agent for amyloid-related...  
WO/2017/164334A1
The purpose of the present invention is to provide a novel boron-containing compound which exhibits excellent accumulation in cancers due to the EPR effect, which does not take nanoparticle form and therefore exhibits high penetration in...  
WO/2017/164268A1
The purpose of the present invention is to provide an excellent composition for a charge transport film and an electron-accepting compound with which it is possible to obtain an organic electroluminescent device which has excellent heat ...  

Matches 1 - 50 out of 8,852