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WO/1991/018616A1 |
The invention concerns a composite molecular system for use in restitutive chemotherapy against viral infections, the system being obtained as follows: (I) preparing lignin units high in polysaccharides (PLP) by: extraction, in weakly ac...
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WO/1991/015496A1 |
An essentially pure substance has a structure of a Nod factor or one of its analogues. The Nod factor is characterized by the fact that its biosynthesis is controlled by at least one nodulation gene (nodA,B,C) common to the Rhizobiaceae,...
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WO/1991/006547A1 |
Alkaloid dimers formed by reacting either Castanospermine or Swainsomine with a compound of formula (1) in the presence of beta cyclo-dextrin glucosyl transferase. The novel dimers are useful as antiviral agents. Pharmaceutical compositi...
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WO/1991/001741A1 |
The invention relates to an aqueous extract of the Acanthospermum hispidum plant and its use as a medicament. The extract is effective as an immunomodulator, in the remedy of radiation sickness, in the prophylaxis and therapy of virus di...
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WO/1991/000319A1 |
Low particles size colloidal overbased calcium sulphonates in admixture with polymeric materials are formed into high solids content coating compositions for corrosion protection.
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WO/1991/000328A1 |
Basic calcium sulphonate is produced by carbonating a substantially oil free mixture of a sulphonic acid and/or an alkaline earth metal sulphonate, a hydrocarbon solvent, an alcohol containing from 1 to 5 carbon atoms and an excess relat...
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WO/1990/015525A1 |
Aqueous solutions of partial hydrolysates of algae, optionally labelled with stable isotopes, are used as growth media for cells.
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WO/1990/015062A1 |
This invention relates to novel acidic polycyclic ether antibiotics CP-91,243 and CP-91,244 of formula (III) wherein R is H in CP-91,243 and R is CH3 in CP-91,244. The invention also relates to novel Actinomadura roseorufa microorganisms...
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WO/1990/013607A1 |
A liquid composition is described which comprises (A) a major amount of at least one fluorine containing hydrocarbon containing one or two carbon atoms; and (B) a minor amount of at least one soluble organic lubricant comprising at least...
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WO/1990/003178A1 |
This application relates to an anti-inflammatory and analgesic compound, a method for its preparation, a pharmaceutical composition including it and a method of treating auto-immune diseases. The anti-inflammatory and analgesic compound ...
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WO/1990/002132A1 |
Constituents of the non-protein-nitrogen fraction of untreated raw milk or fresh milk have a characteristic pharmacological activity.
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WO/1990/001487A1 |
A dibenzocyclooctadiene type lignan can be effectively obtained by extracting a plant containing the same with a solvent having a low polarity, subjecting the extract to partition extraction at least once using a water-insoluble solvent ...
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WO/1989/012626A1 |
Ozonides of terpenes are disclosed. Terpenes which are believed to be pharmacologically active when prepared in accordance with the present invention include: limonene, citronella, alpha-carotene, beta-carotene, Vitamin A, linalool, lina...
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WO/1989/009608A1 |
A variety of hypoglycemic compositions for use in the management of maturity onset non-insulin dependent diabetes mellitus (NIDDM) are disclosed. Suitable hypoglycemic compositions include a polar solvent extract of at least one part of ...
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WO/1989/009602A1 |
The invention relates to a substantially pure anti-inflammatory factor isolated from milk collected from a milk producing animal, to the purification, identification, and characterization of said factor, and to a method for treating infl...
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WO/1989/009059A1 |
Method of treating retrovirus infection by administering extract of Phyllanthus niruri.
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WO/1989/007608A1 |
A calcium channel composition is isolated from neuronal cell membranes by hydrophobic affinity chromatography. The affinity adsorbent used in the isolation technique is a calcium channel blocking factor derived from the venom of funnel w...
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WO/1989/006682A1 |
Sulfurized mixtures which include (A) at least one partial fatty acid ester of a polyhydric alcohol, and (B) at least one member of the group consisting of (1) at least one fatty acid ester of a polyhydric alcohol, which fatty acid ester...
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WO/1989/006539A1 |
A process is described for extracting a pharmaceutically active polysaccharidic substance from the aloe plant. The pharmaceutically active polysaccharidic substance and its characteristic properties are described.
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WO/1989/006683A1 |
Mixtures of partial fatty acid esters of polyhydric alcohols and sulfurized compositions. Compositions comprising these mixtures are useful as additives for a wide variety of lubricants.
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WO/1988/010297A1 |
Recombinant DNA expression vectors or cloning vehicles capable of expressing a polypeptide displaying the antigenicity of an allergen of house dust mites of the genus Dermatophagoides. A synthetic protein or polypeptide displaying the an...
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WO/1988/009336A1 |
Substantially pure saponins are disclosed. The saponins of the present invention are useful as immune adjuvants. Disclosed as well are immune response-provoking compositions comprising an antigen in admixture with the substantially pure ...
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WO/1988/009372A1 |
A recombinant DNA molecule comprising a nucleotide sequence which codes an expression for a fusion protein in which a foreign protein or peptide is fused with the enzyme glutathione-S-transferase, is disclosed, as well as expression vect...
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WO/1988/007031A2 |
A process for producing a sulfurized olefin product substantially free of ash containing waste is disclosed. The process involves dehydrohalogenation of an olefin/sulfur halide complex by contacting the complex with a protic solvent in t...
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WO/1988/004685A2 |
A process of preparing an overbased composition by the reaction of oil soluble organic acids with oxides or hydroxides of, e.g., zinc, copper, cadmium, transition metals, etc. to form a salt. Additional oxides or hydroxides are added alo...
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WO/1988/004689A1 |
A synthetic peptide or polypeptide displaying the antigenicity of all or a portion of the 70kd mitochondrial autoantigen of primary biliary cirrhosis, or an antigenically active fragment thereof, is produced by recombinant DNA techniques...
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WO/1988/004661A1 |
The antibiotic is obtained by culturing microorganisms belonging to the genus Pseudomonas, has antibacterial and oncostatic activities, and has the following physical and chemical properties: (1) molecular weight: 469; (2) melting point:...
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WO/1988/004175A1 |
A biologically active agent extracted from female breast cyst fluids displays anti-hypertensive activity in mammals. The agent is also useful in the treatment of congestive heart disease, atrial fibrillation and idiopathic edema in mammals.
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WO/1988/003133A1 |
Novel compositions of matter comprising monoalkylphenols prepared by selectively alkylating the olefin component of a thermally cracked sulfur-containing petroleum distillate derived from residua. The monoalkylphenols have certain ortho ...
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WO/1988/002755A1 |
Antibiotic A 40926 complex or a factor thereof are microbially deacylated to produce novel de-acyl A 40926 antibiotics of formula (I) wherein A represents a 2-amino-2-deoxy-beta-D-glucopyranosiduronic acid group and B represents hydrogen...
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WO/1988/002771A1 |
Sulfur-containing composition comprising the combination of: (A) at least one first sulfur-containing material which comprises the reaction product of a sulfur source and at least one Diels-Alder adduct in a molar ratio of at least 1.7:1...
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WO/1988/001639A1 |
Remarkably good surfactancy characteristics are exhibited by alkylene oxide (e.g., ethylene oxide, propylene oxide, etc.) adducts of relatively low degree of polymerization (D.P.), long chain glycoside compositions of the sort which are ...
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WO/1988/000200A2 |
Novel process for the preparation of the antibiotics 10381b and to a method of using antibiotics 10381b to promote growth in meat-producing animals. These antibiotics are obtained by the fermentation of a nutrient medium with the novel m...
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WO/1987/007610A2 |
Novel compounds ecteinascidins 729, 743, 745, 759A, 759B, and 770 having antibacterial and antitumor properties.
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WO/1987/006838A1 |
An immunogenic conjugate which is the reductive amination product of an immunogenic capsular polymer fragment having at least one reducing group and derived from a bacterial capsular polymer of a bacterial pathogen, and a bacterial toxin...
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WO/1987/006265A1 |
These compounds are prepared by culturing bacteria belonging to the genus Streptomyces. They have antibacterial and oncostatic activities and are useful as medicines.
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WO/1987/005939A1 |
Variant xanthan gums, including non-acetylated, non-pyruvylated, non-acetylated and non-pyruvylated, and fully-acetylated xanthan gums and other gums which are structurally-related to xanthan gum such as acetylated polytetramer and non-a...
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WO/1987/003200A1 |
A glucose tolerance factor which reduces blood sugar in mammals and is derived from yeast. The glucose tolerance factor can be isolated from autolyzed brewer's yeast extract by sequential fractionation on Sephadex G-75, Biogel P-6, Bioge...
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WO/1987/002588A1 |
A novel recovery process for obtaining the small molecular weight, digitalis-like factor, and purification of the digitalis-like factor. This invention also relates to the identification and characterization of the factor and to therapeu...
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WO/1987/000833A1 |
Sulfur-containing compositions which are prepared by sulfurizing (A) at least one fatty acid ester of a polyhydric alcohol, or (B) at least one fatty acid, fatty acid ester of a monohydric alcohol, or a mixture thereof, or (C) at least o...
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WO/1986/006371A1 |
Sulfur-containing compositions which are prepared by sulfurizing (A) at least one fatty acid ester of a polyhydric alcohol, or (B) at least one fatty acid, fatty acid ester of a monohydric alcohol, or a mixture thereof, or (C) at least o...
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WO/1986/005689A1 |
A novel drug comprises as active ingredient an extract extractable from plant material of plants belonging to the genus Caesalpinia, one or several components of this extract and/or several substances present in this extract or derived t...
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WO/1986/003410A1 |
A new method of cloning large fragments of DNA by inserting the fragment into a cloning vehicle which also contains a high copy plasmid and a partition locus. The process of the invention is particularly useful for producing 987P fimbria...
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WO/1986/002638A1 |
A sulfurized composition prepared by sulfurizing a mixture of at least one terpene and at least one other olefinic compound. More particularly, sulfurized compositions prepared by sulfurizing a mixture of pine oil and at least one other ...
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WO/1986/001981A1 |
An insecticidal fraction is obtained from black pepper by means of a process which consists of the following steps: a) extraction of black pepper, in ground form, by means of CO2 at 30o-70oC and at 150-500 bar; b) separation of the stron...
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WO/1986/001802A1 |
DNA molecules comprising artificially constructed polynucleotide sequences substantially corresponding to all or a portion of the base sequence coding for an antigen of Plasmodium falciparum selected from the group consisting of the RESA...
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WO/1985/005122A1 |
A material being a dsRNA gene segment coding for the major outer capsid glycoprotein of a rotavirus.
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WO/1985/004408A1 |
Antibiotic TAN-588 produced by bacteria belonging to genus Empedobacter, and its salts have an anti-bacterial effect on gram-positive and negative bacteria, and can be used for treating bacteria-induced diseases of mammals and poultry.
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WO/1985/004188A1 |
DNA sequence coding for a mammalian granulocyte macrophage colony stimulating factor (GM-CSF), a method of obtaining same, vectors and hosts harboring same. The sequence is useful as a probe for identifying related sequences, selecting G...
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WO/1985/003441A1 |
An erection and fertility promoting agent which contains as its active component such lipid fractions derived from Cowper's and/or Bartholin's glands as those which contract gerbil colon. The invention also relates to a method for produc...
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