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Matches 1 - 50 out of 4,400

Document Document Title
WO/2019/140147A1
Methods for identifying or monitoring or treating HIV persistence or the development of an HIV-comorbidity in an HIV+ subject involve certain selected glycan dysregulations. In certain embodiments, hyposialylation in the total IgG glycom...  
WO/2019/136399A1
A synthetic dystroglycan oligosaccharide comprising Formula (I) wherein a repeating disaccharide motif consists of Glucuronic Acid (ClcA) and Xylose (Xyl) having a defined glycosyl connection GlcA-β-(1→3)-Xyl-α-(1→3)-GlcA; wherein ...  
WO/2019/128410A1
The present invention relates to the preparation of various xylan esterification products, and an application thereof in a drug for preventing, alleviating and/or treating inflammatory diseases. The application of a xylan esterification ...  
WO/2019/127004A1
The present invention falls within the field of biomedical technology, and in particular relates to modified oligonucleotides and a compound that can be used for synthesizing same, and a method for modifying oligonucleotides. The present...  
WO/2019/119134A1
An immunogenic glycan compound has a poly-β-1,4-ManNAc repeating-unit structure variably modified with 6-linked phosphoethanolamine and 6-linked phosphoglycerol.  
WO/2019/120299A1
Provided are a liver specific delivery (LSD)-based anticancer prodrug nucleoside cyclic phosphate compound and an application thereof, and in particular, a compound represented by formula (I) as well as isomers, pharmaceutically acceptab...  
WO/2019/119628A1
Disclosed in the present invention is a method for preparing tulathromycin.  
WO/2019/122084A1
It relates to a process for the preparation of nicotinamide riboside chloride of formula (I) wherein R1-R4 are as defined herein, comprising the following steps: a) reacting a riboside precursor wherein the hydroxyl groups at positions 1...  
WO/2019/118476A1
The presently disclosed subject matter relates to processes for isolating xylose from an aqueous solution. A representative process can comprise providing an aqueous solution comprising xylose; combining a boron compound with the aqueous...  
WO/2019/114406A1
An absorbable iron-based implantable device, comprising an iron-based substrate and a hydrophobically-modified high polysaccharide attached to the iron-based substrate. The solubility of the modified high polysaccharide in an organic sol...  
WO/2019/110804A1
Disclosed is a method for the manufacture of a spray-dried powder consisting essentially of LNT and/or LNn T, the spray-dried powder, its use for the manufacture of nutritional compositions, and nutritional compositions containing the sp...  
WO/2019/110806A1
Disclosed is a method for the manufacture of a spray-dried powder consisting essentially of at least one lacto-N-fucopentaose, the spray-dried powder, its use for the manufacture of nutritional compositions, and nutritional compositions ...  
WO/2019/110803A1
Disclosed is a method for the manufacture of a spray-dried powder consisting essentially of 3'-SL and/or 6'-SL, the spray-dried powder, its use for the manufacture of nutritional compositions, and nutritional compositions containing the ...  
WO/2019/109300A1
Improved enrichment methods for preparing tannic acid compositions that have superior potency in inhibiting D-amino acid oxidase, and superior purity and safety profiles. The tannic acid compositions (e.g., pharmaceutical compositions, n...  
WO/2019/110801A1
Disclosed is a method for the manufacture of a spray-dried powder consisting essentially of 3-fucosyllactose, the spray-dried powder, its use for the manufacture of nutritional compositions, and nutritional compositions containing the sp...  
WO/2019/109833A1
The present utility model provides a device for continuously producing sugar by hydrolyzation using a lignocellulosic raw material. The device comprises: an acid liquid outputting unit, a raw material mixing unit, a feeding unit, a main ...  
WO/2019/113032A1
High surface area metal catalysts, and methods of making and using the same, are described.  
WO/2019/110800A1
Disclosed are spray-dried powders containing a mixture of structurally distinct human milk oligosaccharides, methods for the production of said spray-dried powder, its use for the manufacture of nutritional compositions, and nutritional ...  
WO/2019/106192A1
Saponin extracts containing at least 93% QS-21 main peak and 0.25-3% 2018 component by UV absorbance at 214 nm, methods for making said extracts, their use as vaccine adjuvants and related aspects.  
WO/2019/106564A1
Methods and systems are disclosed for selectively removing naturally-occurring sugars in beverages in an effective, affordable and scalable manner.  
WO/2019/101629A1
The present invention concerns an efficient way to isolate L-fucose from a fermentation broth. The L-fucose contained in the fermentation broth is produced by microbial fermentation (bacterial or yeasts). The inventive process comprises ...  
WO/2019/100920A1
Disclosed is a method for the rapid preparation of an oligosaccharide from a biomass sugar as a raw material. In the method, biomass sugar is placed in a quartz tube tubular reactor, and under the protection of nitrogen, the quartz tube ...  
WO/2019/104253A1
Novel cultivars of Stevia rebaudiana plant, with a novel genetic trait of self-compatibility, and the advantageous use of this genetic trait in Stevia rebaudiana crossing breeding for increasing steviol glycosides production, including f...  
WO/2019/101489A1
The present invention describes an efficient way to isolate a sialic acid from a fermentation broth. The sialic acid contained in the fermentation broth is produced by bacterial fermentation. The inventive process comprises a step of rem...  
WO/2019/067624A9
Provided is a method comprising (a) providing a hydrolysis composition of at least 20 wt% of sugar equivalents, wherein the hydrolysis composition comprises a first oligosaccharide, water, optionally a soluble aromatic compound, (b) cont...  
WO/2019/097233A1
The invention relates to the use of an amine masked moiety in a method of enzymatic nucleic acid synthesis. The invention also relates to said amine masked moieties per se and a process for preparing nucleotide triphosphates comprising s...  
WO/2019/090802A1
Disclosed are a diglycosylated benzophenoxazine photosensitizer and a preparation method and the use thereof. The present invention greatly improves the enriched concentration of the photosensitizer in tumor cells by taking full advantag...  
WO/2019/092572A1
The present invention relates to new synthetic molecules with agonist activity of human Toll-like Receptor 4 (TLR4), compositions comprising them and uses thereof for the treatment of diseases in which it is useful to induce or increase ...  
WO/2019/092546A1
The present invention relates to a process for the preparation of Cangrelor in salt form of formula (V) by preparation and subsequent hydrolysis of an intermediate of formula (IV). The process is characterised by the high yield and purit...  
WO/2019/087810A1
The present invention is capable of producing a 1,3,4,6-tetra-O-acyl-2-deoxy-2-fluoroglucose in high yield by reacting a 1,3,4,6-tetra-O-acyl-2-O-(trifluoromethylsulfonyl)-β-D­man opyranose with hydrogen fluoride in the presence of a s...  
WO/2019/083204A1
The present invention relates to a method for preparing a DNA oligomer into which a single nucleotide is incorporated using a terminal deoxynucleotidyl transferase. According to the present invention, by using a base hydrolysis reaction ...  
WO/2019/080724A1
Disclosed are a nucleoside phosphate compound, a pharmaceutical composition comprising same, and a preparation method therefor and the use thereof. Such a compound can be successfully metabolized within liver cells, and can produce an ac...  
WO/2019/079613A1
The present disclosure relates to novel methods for preparing antibacterial sisomicin-type aminoglycoside compounds, as well as to related intermediates, and crystal forms thereof, useful in such methods.  
WO/2019/072005A1
The present invention relates to an azacitidine disaccharide impurity, a preparation method therefor and use thereof. A compound of formula III is obtained by reacting a compound represented by formula IV as a start raw material with a t...  
WO/2019/072045A1
A high-affinity CD169 anti-tumor compound and a preparation method therefor, and an application thereof. The high-affinity CD169 anti-tumor compound is a 9-benzopyran thiophene N-acetylneuraminic acid monosaccharide (TCC-Neu5Ac) or a hom...  
WO/2018/053135A9
The present disclosure provides a novel sweetener composition of improved taste of the sweetener (e.g., reduced bitterness and/or astringency, and improved overall sweet quality of the composition); food and beverage products containing ...  
WO/2019/036029A4
Compounds and methods for purifying oligonucleotides such as RNA and DNA. A target oligonucleotide is reacted with an orthoester linker comprising an affinity tag to form an orthoester oligonucleotide-orthoester linker conjugate which is...  
WO/2019/068583A1
The presently claimed invention is directed to a process for preparing D-glucaro-6,3-lactone monoamide from D-glucaro-6,3-lactone.  
WO/2019/067812A1
Methods of preparing steviol glycosides, including Rebaudioside D, Rebaudioside E, Rebaudioside M, Rebaudioside N and Rebaudioside O are provided herein. Sweetener and sweetened consumables containing Rebaudioside D, Rebaudioside E, Reba...  
WO/2019/063757A1
The invention relates to a process for the purification of a neutral human milk oligosaccharide (HMO) from a fermentation broth, the process comprising the steps of: (i) separating biomass from the fermentation broth to provide a crude s...  
WO/2019/067624A1
Provided is a method comprising (a) providing a hydrolysis composition of at least 20 wt% of sugar equivalents, wherein the hydrolysis composition comprises a first oligosaccharide, water, optionally a soluble aromatic compound, (b) cont...  
WO/2019/063803A1
The present invention relates to new methods and reagents for coupling molecules by a so-called click reaction in the presence of a suitable catalyst and a metal cation. Further, the invention relates to an activator composition for such...  
WO/2018/236184A3
The present application relates to a method for producing D-psicose, the method comprising the steps of: putting a composition containing a D-psicose borate complex into chromatography comprising a divalent cation; and separating the com...  
WO/2019/055331A1
Methods and compositions for extracting nucleic acids such as microRNAs (miRNAs) from biological samples are provided. Aspects of the methods include contacting a biological sample with proteinase K followed by contact with ferric oxide ...  
WO/2019/052359A1
The aim of the present invention is to provide a compound containing a diheterocyclic ribavirin analog, a stereoisomer, a prodrug, a pharmaceutically acceptable salt, a compound salt and/or a solvated compound with structural general for...  
WO/2019/053659A1
The present disclosure relates to compounds and compositions containing 5'-phosphoramidite nucleoside monomers of formulae (I) and (II), and methods of making and use, wherein the substituents are as defined in the appended claims.  
WO/2019/053476A1
The present invention relates to a process for the preparation of floxuridine, said process comprising reacting a compound of Formula la with a compound of Formula lla in the presence of an acid Al to provide a compound of Formula Ilia i...  
WO/2019/047848A1
The invention belongs to the field of quality analysis and control of traditional Chinese medicine, and provides a method for separating eighteen components in a traditional Chinese medicine composition, comprising: (1) preparing the tra...  
WO/2019/048881A1
The present invention relates to a process for preparing oligonucleotides or oligonucleotide analogues comprising triazole and (phosphor)amidate internucleoside linkages. The present invention also relates to the oligonucleotides and oli...  
WO/2019/043029A1
Disclosed is a method for purifying sialylated oligosaccharides from a fermentation broth, cell-lysate or biocatalytic reaction mixture for obtaining high amounts of desired sialylated oligosaccharides in high purity. The method is parti...  

Matches 1 - 50 out of 4,400