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WO/2022/078487A1 |
The present disclosure provides a zolinose compound represented by formula (I), a preparation method therefor and a use thereof, wherein definitions of substituents are provided in the description. The zolinose compound has application p...
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WO/2022/077923A1 |
The present invention relates to the technical field of radiopharmaceutical chemistry and clinical nuclear medicine, in particular to a benzene ring-containing glucose derivative and an application thereof. The benzene ring-containing gl...
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WO/2022/056840A1 |
The present application provides a post-treatment method of a sucrose-6-carboxylic ester chlorination reaction liquid. The method comprises: adding ammonia water or water into the sucrose-6-carboxylic ester chlorination reaction liquid t...
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WO/2022/056913A1 |
Provided is a preparation method for sucrose-6-carboxylate. The method of the present application comprises: passing a mixed solution containing sucrose, a mixed solvent and an organotin compound through a gas-liquid exchange reactor, an...
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WO/2022/051988A1 |
The present application provides a method for preparing sucrose-6-ester, comprising: preparing a reaction solution of sucrose and an organotin compound; atomizing the reaction solution to form small droplets; fully mixing and contacting ...
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WO/2022/015917A1 |
Provided are methods of detecting a biomolecule of interest in a sample. In certain embodiments, the methods comprise contacting the sample with a biolayer interferometry (BLI) sensor, the BLI sensor comprising a capture antigen specific...
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WO/2021/248696A1 |
A separation and purification method for N-acetylglucosamine of the present invention relates to the technical field of bioengineering. In the present invention, a raw material liquid containing N-acetylglucosamine is obtained by means o...
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WO/2021/205631A9 |
The present invention addresses the problem of providing a pharmaceutical having, as an active ingredient, a compound having agonistic activity on STING. As a result of having performed thoroughgoing studies, the inventors discovered, ...
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WO/2021/245587A1 |
The present invention relates to a method for producing a cellulose-based product having lipid resistance, said method comprising - providing an aqueous mixture comprising cellulose pulp, said mixture having a solid content between 0.1- ...
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WO/2021/232932A1 |
A method for preparing high-purity granatin A: by means of a combination of low-temperature liquid phase chromatography and an isomerisation conversion purification method, using pomegranate peel extract as a source material, granatin A ...
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WO/2021/231751A1 |
The invention provides compositions and methods for utilizing oligosaccharides, such as isolated human milk oligosaccharides, to attenuate a respiratory pathogen infection and/or to promote recovery from a respiratory pathogen infection ...
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WO/2021/213500A1 |
A compound of Formula (I) : (I) or a pharmaceutically acceptable salt thereof, in which Ring X is a 3 to 7 membered monocyclic ring, at least one of R1, R2, R3, and R4 is OR5 or CH2OR5 and the other R1, R2, R3, and R4 each independently ...
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WO/2021/211201A1 |
The present disclosure provides to a novel flame retardant resin, wherein the resin is a reaction product of an epoxy material, a curing agent, and a partially esterified tannic acid of formula (I), wherein TA represents a tannic acid mo...
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WO/2021/207858A1 |
Methods of diagnosing COVID-19 infection in a subject comprising: (a) obtaining a test sample from the subject (b) comparing levels of a biomarker in the test sample with known normal reference levels of the biomarker, wherein an increas...
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WO/2021/198160A1 |
The present invention relates to a process for preparing a compound of formula (X), wherein said process is suitable for large scale synthesis.
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WO/2021/143194A1 |
The present invention relates to a catalyst for a phosgenation reaction and a phosgenation reaction method. The catalyst for a phosgenation reaction of the present invention is a phosphinyl ionic liquid as represented by general formula ...
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WO/2021/143812A1 |
The present invention relates to a method for preparing compound I, N-(β-L-rhamnopyranosyl)ferulamide, and the use of compound I in the preparation of a medicament for alleviating or treating mitochondrial dysfunction and Aβ-induced mi...
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WO/2021/115380A1 |
Disclosed is a compound having a neuroprotective effect, a preparation method therefor and a use thereof. Specifically, the compound has the structure shown by formula A, the definition of each group and substituent being as described in...
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WO/2021/114200A1 |
A preparation method for sugar esters, wherein sucrose and hydrogenated palm oil undergo a transesterification reaction without the addition of a solvent to obtain a crude products of sugar esters. The preparation method does not use sol...
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WO/2021/094459A1 |
The present invention relates to a method for drying human milk oligosaccharides (HMOs). More specifically, the present invention is related to a method of roller drying or drum drying of human milk oligosaccharides in a simple and econo...
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WO/2021/083735A1 |
Method for synthesizing 1,6-anhydro sugars – in particular sugars that may be used as intermediates for making fondaparinux.
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WO/2021/056324A1 |
Provided is a green chemical preparation method for alpha-tri-O-acetyl glucuronic acid methyl ester bromo compound. The method uses sodium bromide, sulfuric acid and methyl tertiary ether system to replace the traditional hydrobromic aci...
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WO/2021/056382A1 |
Provided is a preparation method for alpha-penta-O-acetyl mannose. A study is performed using natural mannose as a raw material on the basis of the conventional acetic anhydride acetylation process. A catalytic amount of cesium fluoride ...
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WO/2021/055933A1 |
The present disclosure relates to disaccharides with defined sulfation patterns, and oligosaccharide mimetics comprising the disaccharides as repeating units linked in a head to tail fashion. The present disclosure further relates to met...
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WO/2021/050778A1 |
The present disclosure provides compositions and methods for enhancing immune response in a subject. In an embodiment, this disclosure provides modified LPS molecules and compositions comprising the modified LPS molecules. The disclosure...
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WO/2021/042922A1 |
Disclosed is a preparation method for tetragalloylglucose. The method comprises: using Camellia ptilophylla Chang as a raw material for extraction, purifying the Camellia ptilophylla Chang extract by using a macroporous adsorption resin,...
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WO/2021/022565A1 |
A sucrose fatty acid ester, a preparation method and a quantitative analysis method therefor, and an application thereof. The preparation method comprises the following steps: (1) adding sucrose, a fatty acid methyl ester, a catalyst, an...
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WO/2021/022819A1 |
The present invention relates to an isomerization feature-based purification and preparation method of punicalagin. The method uses a pomegranate peel extract as a raw material, avoids impurities contained in punicalagin on the basis of ...
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WO/2021/019509A1 |
The present document relates to a process for the preparation of the crystalline form II of sotagliflozin from compound of formula (A), said process being continuously performed and comprising at least the steps of: a) performing in a re...
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WO/2021/019507A1 |
The present document relates to a process for the preparation of the crystallineform II of sotagliflozin, wherein said crystalline form II of sotagliflozin is directly obtained from the following compound of formula (A) and by using tolu...
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WO/2021/013155A1 |
Disclosed are a new glycosyl donor, a preparation method therefor, and an application thereof. Specifically, a glycosyl donor represented by formula (I), a preparation method therefor, and a use of the glycosyl donor represented by formu...
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WO/2021/000041A1 |
The present document describes compounds, or pharmaceutically acceptable salt thereof, of a core formula (I) Wherein R1 includes an amino group. These compounds are particularly useful in the formulation and in vivo and ex vivo delivery ...
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WO/2020/248068A1 |
The present application provides a synthetic method for production of 3-azido-3-deoxy-D-galactopyranose. Also provided are methods of using the 3-azido-3-deoxy-D-galactopyranose in the manufacture of galactoside galectin antagonists, suc...
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WO/2020/228436A1 |
The present invention relates to aromatic ring or heteroaromatic ring derivatives, a preparation method therefor and applications thereof in medicine. Specifically, the present invention relates to aromatic ring or heteroaromatic ring de...
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WO/2020/211668A1 |
Disclosed are compounds that are inhibitors of CD73 and are useful in treating CD73-associated diseases or conditions, and compositions containing the compounds.
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WO/2020/202790A1 |
The purpose of the present invention is to provide: a novel compound which has an antioxidative effect; and use of the compound. The present invention achieves the above-described purpose by providing a compound represented by formula (1...
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WO/2020/183442A2 |
The present disclosure relates to phenylpropanoid saccharide esters, methods for the synthesis of libraries of phenylpropanoid saccharide esters with different degree and place of substitution in the sugar core, and their use as antimicr...
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WO/2020/178798A1 |
The present disclosure describes acyl halide liquid dispersions and tunable methods of treating cellulosic materials with compositions that provide increased hydrophobicity and/or lipophobicity to such materials without sacrificing the b...
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WO/2020/140559A1 |
Provided is a 5-deoxy-D-ribose derivative (III), when the derivative (III) is used for preparing capecitabine, the stereoselectivity is good and the yield is high. Further provided is a preparation method of the derivative, wherein the p...
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WO/2020/132625A1 |
Methods for the preparation of oligosaccharide products from polysaccharide starting materials are disclosed. The methods include: hydrolyzing a glucosamine-containing polysaccharide starting material, such as heparin or heparosan, under...
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WO/2020/132096A1 |
The invention provides methods for preparing antibodies and antibody derivatives with controlled levels of core fucosylation. In one aspect, provided herein is a method of controlling the level of afucosylation of an antibody or antibody...
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WO/2020/106870A2 |
Provided herein are genetically modified yeast cells capable of producing one or more human milk oligosaccharides. The yeast cells include one or more heterologous nucleic acids that encode enzymes of a human milk oligosaccharide biosynt...
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WO/2020/087499A1 |
Disclosed is a method for preparing a flame retardant silk, the method comprising the following steps: soaking silk in a tannic acid solution with a pH value of 3-4, and raising the temperature to 80-90℃ for a temperature holding treat...
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WO/2020/083733A1 |
The present invention relates to the compounds of formula (I), and the N-oxides, stereoiso- mers, tautomers and agriculturally or veterinarily acceptable salts thereof wherein the variablesare defined according to the description, (I) Th...
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WO/2020/082162A1 |
An adjuvant formulation includes a monophosphoryl Lipid A (MPLA) analogue, a Pam3CSK4 analogue, or a muramyldipeptide (MDP) analogue, or combinations thereof. The adjuvant may be formulated in soluble form or in a nanoparticle, such as p...
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WO/2020/078807A1 |
The present invention relates to a prodrug compound of the general formula I or II. The prodrug compound of formula I or II is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3...
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WO/2020/078808A1 |
The present invention relates to a compound of the general formula I or II. The compound of formula I or II is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in ...
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WO/2020/064787A1 |
The present disclosure relates generally to terpene glycosides, such as certain such compounds extracted from Stevia rebaudiana Bertoni, Rubus suavissimus, or Siraitia grosvenorii. The disclosure also provides for the use of such compoun...
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WO/2020/068235A1 |
A method of treating cellulosic materials with a barrier coating comprising at least two polyol and/or saccharide fatty acid ester, having different HBL values, that provides increased water, oil and grease resistance to such materials w...
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WO/2020/068582A1 |
An alkyd polymer composition for fast-drying, low VOC applications is provided. The alkyd polymer incorporates a minimum required level of a cyclic ether- and hydroxyl-containing composition formed from a sugar alcohol during the alcohol...
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