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Patent Searching and Data


Matches 201 - 250 out of 2,778

Document Document Title
WO/2015/118498A1
The present invention relates to a stabilized kit for the preparation of a radiopharmaceutical. In particular, the present invention relates to the use of a non-aqueous solvent for the stabilisation of the ligand component of the kit.  
WO/2015/111627A1
The purpose of the present invention is to provide an amino acid precursor capable of improving the properties (especially water solubility, stability in water, bitterness, and the like) of an amino acid and being converted into an amino...  
WO/2015/112016A1
The present invention relates to a cycloaddition process comprising the step of reacting a halogenated aliphatic 1,3-dipole compound with a (hetero)cycloalkyne according to Formula (1): Preferably, the (hetero)cycloalkyne according to Fo...  
WO/2015/093929A1
The present invention relates to the synthesis of bioconjugate molecules, from among two or more of the following functional groups: sugars, prebiotics, oligosaccharides, polysaccharides, triglycerides, fatty acids, fatty acid esters, an...  
WO/2015/092374A1
There is provided a method for the chlorination of a sucrose-6-acylate to produce a 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose-6-acylate, wherein said method comprises the following steps (i) to (v): (i) providing a first compone...  
WO/2015/092720A1
Provided herein are metabolites of N-(6-((2R,6S)-2,6-dimethylmorpholino)pyridin-3-yl)- 2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide (Sonidegib, LDE225) that modulate the activity of the Hedgehog signaling pathway and tha...  
WO/2015/070571A1
The present invention relates to a disaccharide intermediate and a synthesis method thereof, relates to the chemical pharmaceutical field, and more specifically relates to a method for preparing a disaccharide segment of a key intermedia...  
WO/2015/063500A1
A glycan having the structure galβ1-3GLc Nacβ1-3Galβ1-4(Fucα1-3)Glc NAc (LecLex) which is attached to a lipid or protein backbone, and isolated binding members capable of binding thereto.  
WO/2015/020073A1
Provided is a method for producing sucrose fatty acid ester having suppressed coloration and a negligible amount of residual organic solvent. A method for producing sucrose fatty acid ester that acquires sucrose fatty acid ester from a r...  
WO/2014/196887A1
Derived for the first time are individual (without the addition of penta- and hexa-acyl derivatives) di-, tri- and tetra-acyl S-LPS of endotoxic bacteria and combinations thereof, and the immunobiological, physicochemical and chemical...  
WO/2014/182966A1
Methods are provided herein for preventing, delaying the onset of or reducing the progression of colorectal tumorigenesis in a subject identified as at risk of colorectal tumorigenesis, comprising adjusting the composition of gut microbi...  
WO/2014/177771A1
The invention relates to a glycoprotein-toxic pay- load molecule conjugate, a toxic payload molecule- glycan conjugate, and a pharmaceutical composi- tion.The invention further relates to a method for preparing the glycoprotein-toxic pay...  
WO/2014/161960A1
Isotopically-labelled glycans and their synthesis and use as internal standards in the analysis by mass spectrometry of glycan mixtures is described. The methods of synthesis described herein may be used conveniently to prepare libraries...  
WO/2014/147168A1
It was the object to perform surface functionalization with as low as possible a procedural effort and without deleterious side effects, wherein the functionalized surface is to have a permanent chemical activity and a high degree of sub...  
WO/2014/143620A1
The invention provides compounds, formulations and methods for improving plant emergence, growth and yield. More specifically, the present invention relates to compositions comprising the synthetic lipoamino acid glucosamine compounds of...  
WO/2014/138490A1
Compounds that are related to natural synthetic lipochitooligosaccharide analogs were chemically synthesized and found to be effective as plant performance enhancers. The compounds of general formula (I) are amine-oligosaccharides with a...  
WO/2014/132940A1
Provided is a method for producing α-halo-tetraacyl glucose, the efficiency of which is excellent and suited to industrial production. The present invention is a method for producing α-halo-tetraacyl glucose represented by general form...  
WO/2014/124214A1
Naturally-derived compounds having various structures elicit the perception of salty taste, enhance the perception of salty taste of a salt, or act at one or more sodium channels. Food products may include such naturally-derived compound...  
WO/2014/106856A1
The present invention relates to the mannose - receptor selective lysinylated cationic amphiphile and a process for preparation thereof. The compounds of the present invention can target DNA vaccines to antigen presenting cells (APCs) su...  
WO/2014/086373A1
The present invention relates to a method of obtaining a non-acidic human milk oligosaccharide (HMO) or a precursor in crystalline form from an aqueous medium, such as a fermentation broth, by drying the aqueous medium and then treating ...  
WO/2014/077960A1
The present invention provides carbohydrate-based surfactants and methods for producing the same. Methods for producing carbohydrate -based surfactants include using a glycosylation promoter to link a carbohydrate or its derivative to a ...  
WO/2014/053603A1
The invention relates to compounds of formula (I); wherein A and L are as defined in the description. The invention also relates to immunogens obtained from said compounds, and to antibodies raised against said immunogens. The compounds ...  
WO/2014/032188A1
The invention provides compounds for inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and d...  
WO/2014/032187A1
The invention provides compounds of Formula (I) for inhibiting gh cosidases, prodrugs of the compounds, and pharmaceutical compositions comprising the compounds or prodrugs of the compounds. The invention also provides method of treating...  
WO/2014/032185A1
The invention provides compounds for inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and d...  
WO/2014/027203A1
An imaging agent comprising a conjugate of an oligosaccharide moiety with an imaging moiety. The oligosaccharide is Lewis A or Lewis B or a mimetic thereof, or a pharmaceutically acceptable salt or PEGylated form of Lewis A or Lewis B or...  
WO/2014/019855A1
The present invention concerns a method for preparing a creatine fatty ester or derivative thereof comprising at least one step consisting in reacting a diprotected creatinine with a molecule bearing at least one alcohol functional group...  
WO/2014/013495A1
The present invention relates to amphiphilic aminoglycoside (AG) derivatives, especially derivatives of tobramycin, kanamycin A and paromomycin comprising hydrophobic side chains linked to the AG moiety by various linkers. These novel de...  
WO/2013/172436A1
The invention pertains to glycosylated crocin compounds obtained by condensing glucose or glucose oligomer to one or more hydroxyl groups of crocin represented by formula (1) as novel glycosylated compounds of crocin, or a mixture thereo...  
WO/2013/157267A1
[Problem] To provide a novel method for producing an acyl glucuronide which is an ester compound of a compound containing a carboxy group and a glucuronic acid. [Solution] An acyl glucuronide is obtained, for example, by reacting 1-chlor...  
WO/2013/151697A1
The present invention provides moenomycin-based probe compounds of Formula (I) for use in screening inhibitors of bacterial glycosyltransferases. The present invention also provides bacterial glycosyltransferase screening assays using co...  
WO/2013/133271A1
The present invention relates to a trehalose fatty acid ester composition that contains trehalose fatty acid esters, wherein a fatty acid residue having 8 to 22 carbon atoms makes up more than 50 mass% of the total amount of all of fatty...  
WO/2013/115817A1
The present invention relates to a process for the synthesis of the Factor Xa anticoagulent Fondaparinux and related compounds. The invention relates, in addition, to efficient and scalable processes for the synthesis of various intermed...  
WO/2013/100105A1
Provided are: a Maillard reaction inhibitor which can inhibit the progress of a Maillard reaction in a living body effectively, does not cause any adverse side effect, can be applied safely, and can be produced without requiring any comp...  
WO/2013/089792A1
Compositions resulting from the dehydration and esterification of a sugar alcohol (i.e., an alditol). In some particular embodiments, the composition comprises mono-acylated sorbitan and/or mono-acylated isosorbide.  
WO/2013/011098A9
The present disclosure relates to iminosugar derivatives and processes for the preparation thereof. The disclosed compounds have glycosidase inhibiting properties, and are useful in the treatment of various diseases, such as type 2 diabe...  
WO/2013/071409A1
A novel lipoteichoic acid (LTA) was isolated from C. difficile, the structure of which is illustrated below wherein n is an interger between 1 and 20, R3 and R4 are independently selected from C 14:0, C 16:0, C 16: l, C 18:0 or C18: l fa...  
WO/2013/059927A1
The present application relates to the compounds of formula I (I) as well as their use for inhibiting at least one of AKT-1, FAK and PKCα and in the treatment and/or prevention of metastatic diseases.  
WO/2013/050377A1
The present invention relates to the use of a compound of formula (1): wherein - R represents a linear or branched alkyl group comprising from 3 to 27 carbon atoms, said alkyl group being replaced by at least two hydroxyl groups, and opt...  
WO/2013/046180A1
A method that can be used to make a precursor of L-fiicose from D-glucose, that comprises the steps of: a) making a compound of formula (1) from D-glucose, formula (1) wherein R1 is acyloxy, and Q is a group (a), (b), (c) or (d), Formula...  
WO/2013/022985A2
The present invention relates to compounds involved in nematode signaling.  
WO/2013/017254A1
The invention relates to a synthetic oligosaccharide representing part of the repeating unit of the Clostridium difficile glycopolymer PS-I and having the sequence of the pentasaccharide a-L-Rhap- ( 1→3 ) -β-D-Glcp- ( 1→4 ) - [a-L-R...  
WO/2013/004669A1
Helicobacter pylori infects over half of the world's population and thought to be a leading cause of chronic gastritis, peptic ulcer, and gastric cancer. Campylobacterjejuni is another enteric and gastric bacteria which is the most commo...  
WO/2012/160337A1
Compounds which interact with HlsTONES Compounds of Formula I : • 4"'-Sulfo-Fucose [alpha]1-3 (4"-sulfo)-Fucose [alpha]1-3 (4'-Sulfo-Fu- cose [alpha]1-4-Glucuronic acid [beta]1-0-Methyl or • 4" "-Sulfo-Fucose [alpha]1-3 (4"-sulfo)-Fu...  
WO/2012/153128A1
A method of removing a carboxylic acid from a liquid including a tertiary amide solvent includes the steps of: A) forming an extraction medium comprising an acid-extracting tin species and an extraction solvent that is immiscible with th...  
WO/2012/140596A1
The present invention provides a compound of formula I; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a ph...  
WO/2012/137604A1
Provided is a method for producing a diester of a polyhydric alcohol and a fatty acid, the method being provided with a step of obtaining a diester of a polyhydric alcohol and a fatty acid by reacting a monoester of a polyhydric alcohol ...  
WO/2012/129651A1
The invention provides compounds of formula (I) with substituents as specified in claim 1 for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceuticals compositions including the compounds or prodrugs of the com...  
WO/2012/126091A1
The invention provides compounds for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating di...  
WO/2012/103990A1
The present invention relates novel phosphorainidates of monosaccharides of formula (I), wherein R1 is a monosaccharide group selected from A and B: R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16 and X are as defined h...  

Matches 201 - 250 out of 2,778