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Matches 1 - 50 out of 13,312

Document Document Title
WO/2020/104335A1
The present invention relates to a compound of the general formula (1). The compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal...  
WO/2020/102910A1
Herein, we describe the development of non-β-lactam-based potentiator molecules that synergize with β-lactam antibiotics and β-lactam-β-lactamase inhibitor combinations against MDR/XDR P. aeruginosa phenotypes. The compound comprises...  
WO/2020/106636A1
Provided are 13-membered macrolides for the treatment of infectious diseases. The 13- membered macrolides described herein are azaketolides. Also provided are methods for preparing the 13-membered macrolides, pharmaceutical compositions ...  
WO/2020/105054A1
Modified aminoglycoside compounds represented by Formula I as defined and described in the specification are provided. The modified aminoglycosides feature a diamine-containing functional moiety at one or more of positions 3', 4' and 6'....  
WO/2020/072834A9
The invention provides compositions and methods for treating asthma in a subject in need thereof comprising administering chemically synthesized secoisolaricirecinol diglucoside (SDG), and in particular, a racemic mixture of the SDG (LGM...  
WO/2020/057605A3
Disclosed are a glucose compound, a pharmaceutical composition, and an application thereof. The present invention provides the glucose compound as shown in formula (I) or a pharmaceutically acceptable salt thereof, which has almost no ac...  
WO/2020/084094A1
The present invention relates to a process for preparing a nitrated compound, comprising the step of reacting a compound (A) comprising at least one substituted or unsubstituted aromatic or heteroaromatic ring, wherein said heteroaromati...  
WO/2020/086559A1
Methods of isolating dihydrochalcone compounds of Formula (I) from Balanophora harlandii are provided herein. Compositions and consumables comprising at least one sweetener and at least one dihydrochalcone compound described herein are a...  
WO/2020/078807A1
The present invention relates to a prodrug compound of the general formula I or II. The prodrug compound of formula I or II is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3...  
WO/2020/078808A1
The present invention relates to a compound of the general formula I or II. The compound of formula I or II is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in ...  
WO/2020/077970A1
Provided in the present invention is a highly efficient stevioside mixture preparation method, the preparation method comprising the following steps: (1) placing crude stevioside into a sealed pressure-resistant system or apparatus, and ...  
WO/2020/072834A1
The invention provides compositions and methods for treating asthma in a subject in need thereof comprising administering chemically synthesized secoisolaricirecinol diglucoside (SDG), and in particular, a racemic mixture of the SDG (LGM...  
WO/2020/070732A1
The present invention relates to a field of treatment and prevention of overweight and obesity. In particular the present invention is directed to an oral composition comprising (beta)-escin (beta-escin) for use in prevention of extracel...  
WO/2020/063894A1
An industrialization method for comprehensive utilization of stevia rebaudiana. The major improvement is in that the stevia rebaudiana is extracted by using a high-concentration alcohol solution, then the extracted solution is purified b...  
WO/2019/125879A3
The present disclosure provides conjugates which comprise an insulin molecule conjugated via a conjugate framework to one or more separate ligands that include a first saccharide, and wherein the conjugate framework also comprises a fatt...  
WO/2020/069091A1
A method of suspending elemental sulfur in water includes the steps of providing water including elemental sulfur and hydrogen sulfide and adding from about 1 to about 100 parts by weight of a sulfur suspension additive to the water base...  
WO/2020/065309A1
The present invention provides a therapeutic combination for use in treating an infection with a pathogen. The therapeutic combination comprises an aminoglycoside antibiotic; and a nucleic acid monoalkylating agent that substitutes a sin...  
WO/2020/063892A1
Disclosed is an industrial method for simultaneously preparing stevia rebaudiana chlorogenic acid and stevioside. The industrial method includes carrying out alcohol extraction on stevia rebaudiana which is used as a raw material, and th...  
WO/2020/057605A2
Disclosed are a glucose compound, a pharmaceutical composition, and an application thereof. The present invention provides the glucose compound as shown in formula (I) or a pharmaceutically acceptable salt thereof, which has almost no ac...  
WO/2020/058322A1
The present invention provides glucose sensitive insulin derivatives comprising a macrocycle, a glucose mimetic and human insulin or an analogue thereof, and their pharmaceutical use. Furthermore, the invention relates to pharmaceutical ...  
WO/2020/053207A1
The invention relates to an improved method for producing isomalt from a carbohydrate mix containing isomaltulose and saccharose.  
WO/2020/050462A1
The present invention relates to a naphthopyrone derivative and a composition comprising, as an active ingredient, a Cassia obtusifolia shoot extract including the naphthopyrone derivative. A composition according to an aspect of the pre...  
WO/2020/050865A1
A method of treating a triterpene-responsive condition, disease or disorder in a subject by administration of an improved triterpene-based composition is provided. An improved triterpene-based composition comprising at least two or at le...  
WO/2020/034987A1
Disclosed are a compound of formula I of a prodrug of a JAK inhibitor, a pharmaceutical composition thereof, a method for treating inflammatory diseases and tumors by using the compound, as well as a method and an intermediate for prepar...  
WO/2020/032152A1
Current synthesis methods for 4'-substituted nucleoside derivatives include a step in which stereoisomers are produced and therefore have problems such as decreased yield and complication of a refinement step. Thus, a synthesis method ha...  
WO/2020/018474A2
The present invention provides compounds isolated from avocado seeds for use as a natural colorant in edible materials. The compounds of the invention are useful for coloring edible materials red, orange, or yellow. The invention also pr...  
WO/2020/014409A1
Provided herein are senolytic agents for selectively killing senescent cells that are associated with numerous pathologies and diseases, including age-related pathologies and diseases. As disclosed herein, senescent cell-associated disea...  
WO/2020/007760A1
The present invention relates to novel pharmaceutically acceptable salts of TLR4 agonist compounds and forms thereof, corresponding pharmaceutical compositions or formulations, processes or methods of compound preparation and uses or tre...  
WO/2020/001166A1
Disclosed are a glycoside compound represented by formula (III) and a preparation method therefor, a composition, an application, and an intermediate. The provided glycoside compound is simple in preparation method, can remarkably improv...  
WO/2020/001516A1
Rebaudioside A1G, a preparation method therefor, a purification method therefor and a use thereof in food. The preparation method comprises: providing rebaudioside A and a glucose-based donor, and producing rebaudioside A1G by means of t...  
WO/2020/006194A1
Systems and apparatuses for producing microbe-based compositions that can be used in the oil and gas industry, environmental cleanup, as well as for other applications are provided. More specifically, apparatuses comprising two vessels f...  
WO/2019/243825A1
The present invention relates to conjugates of small molecule modulators of the Stimulator of Interferon Genes (STING) protein.  
WO/2018/102447A3
The invention relates to a process for producing food ingredients from Stevia rebaudiana plant and their use in food products, beverages and other consumables. Obtained compositions are useful as flavors, sweeteners, antioxidants, and ot...  
WO/2019/238965A1
The present invention relates to several novel 1-O-glycosylated sphingoid bases and to a production method thereof, as well as to uses of the 1-O-glycosylated sphingoid bases. Sphingoid bases carrying a vinylogous amide-type protecting g...  
WO/2019/234763A1
The present invention discloses lincomycin sustained release tablets. More particularly, the invention discloses sustained release tablets of lincomycin 1000mg for once a day administration.  
WO/2019/230863A1
Disclosed are: a method for manufacturing a compound (5-epi-4"-N-(L-isoceryl)apramycin) and 5-epiapramycin; and an intermediate used for said method. The method of the present invention is useful in that the compound (5-epi-4"-N-(L-isoce...  
WO/2019/227228A1
The present disclosure relates to analogs of N-acetyl glucosamine fluorinated at 4- and/or 6-position(s) and derivatives of xylose at anomeric position for the treatment of a neurological disease, inflammation, cancer and a central nervo...  
WO/2019/222269A1
Provided are biaryl amides and coumarin-based compounds with modified sugar groups for treatment of diseases associated with heat shock protein pathway. The compounds having the following formulas, wherein variables are as defined herein...  
WO/2019/222424A1
Disclosed are cationic lipids which are compounds of Formula (I'). Cationic lipids provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly...  
WO/2019/222601A1
Methods of preparing concentrated solutions of crystalline steviol glycoside compositions having relatively high rebaudioside M content are provided herein. The concentrated solutions are stable and can be used to prepared beverage syrup...  
WO/2019/196920A1
The present application falls within the field of medical technology, and relates to crystals of glycyrrhizic acid derivatives, crystalline compositions, pharmaceutical compositions and uses thereof, in particular relates to type A cryst...  
WO/2019/194858A1
The present disclosure relates to novel methods for preparing antibacterial aminoglycoside compounds and the compounds used in such preparations.  
WO/2019/178116A8
The present disclosure relates to the production of steviol glycosides rebaudioside J and rebaudioside N through the use of rebaudioside A as a substrate and a biosynthetic pathway involving various 1,2 RhaT-rhamnosyltransferases.  
WO/2019/189422A1
A method for separating steviol glycoside(s), said method involving separation step 55 for performing continuous liquid chromatography wherein a liquid to be separated, which contains multiple kinds of steviol glycosides, is passed throu...  
WO/2019/190986A1
Disclosed is a compound of the formula (I) or (II): wherein a f are as described herein. The compounds are useful in the activation of Type II NKT cells and in treating cancer.  
WO/2019/178699A1
The present description relates to glycoconjugates, glycoconjugate immunogens and glycoconjugate vaccines comprising carbohydrate antigens coupled to immunogenic carrier proteins, or materials used for detection and screening of resultin...  
WO/2019/178980A1
A method for preparing gynostemma pentaphylla makino saponin LVI, XLVI, L, LI, Damulin A or Damulin B. In said method, Gynostemma cardiospermum Cogn.ex Oliv is used as a raw material to prepare a high content of target product by means o...  
WO/2019/183159A1
Provided are variants of saponins that are found in Quillaja saponaria (QS) Molina tree bark that are chemically modified to distinguish them from naturally occurring parent saponins. The modified saponins have increased adjunctive activ...  
WO/2019/177634A1
Methods of preparing highly purified steviol glycosides, particularly steviolmonoside, steviolmonoside A, steviolbioside, steviolbioside A, steviolbioside B, rubusoside, stevioside, stevioside A (rebaudioside KA), stevioside B, steviosid...  
WO/2019/178541A1
Methods of using highly purified rebaudioside AM are described. The methods include utilizing enzyme preparations and recombinant microorganisms for converting various staring compositions to target steviol. glycosides. The highly purifi...  

Matches 1 - 50 out of 13,312