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Matches 451 - 500 out of 6,401

Document Document Title
WO/2008/153394
The present invention relates to compounds according to formula (I) : wherein R2 is absent or a linking moiety and R3 is selected from the group consisting of anti- inflammatory agents and pharmaceutically acceptable salts thereof, pharm...  
WO/2008/153394
The present invention relates to compounds according to formula (I) : wherein R2 is absent or a linking moiety and R3 is selected from the group consisting of anti- inflammatory agents and pharmaceutically acceptable salts thereof, pharm...  
WO/2008/151615
The invention relates to a method for producing biosurfactants, according to which micro-organisms producing biosurfactants are moved in a nutrient substrate. According to the invention, the nutrient substrate is used in excess and a mec...  
WO/2008/146917
Compounds represented by the general formula (1) [wherein A is aryl; R1 is N-(optionally substituted C1-6 alkyl)-N-(optionally substituted C1-6 alkyl)amino-C1-6 alkyl; R2 is hydrogen or optionally substituted C1-6 alkyl; R3 is optionally...  
WO/2008/146919
Disclosed is a compound represented by the formula (I) or a pharmacologically acceptable salt or solvate thereof [in the formula (I), A represents an aryl group and R1 represents a 5- or 6-membered monocyclic heterocyclic group, or A rep...  
WO/2008/147725
Exemplary embodiments of this invention encompass a method for purifying a substantially crude stevioside, methods for preparing polymorphic and amorphous forms of stevioside, and the polymorphic and amorphous forms prepared therefrom.  
WO/2008/143677
Stable solid, crystalline forms of elsamitrucin salts are provided that are useful in preparing anti-neoplastic parenteral formulations. Also provided are methods for treating neoplastic diseases in humans using parenteral formulations t...  
WO/2008/142155
The present invention concerns a method for preparing C-6 phosphorylated D- aldohexoses and C-6 phosphorylated D-aldohexose derivatives, new C-6 phosphorylated D-aldohexoses derivatives and uses thereof. The method comprises incubating p...  
WO/2008/142155
The present invention concerns a method for preparing C-6 phosphorylated D- aldohexoses and C-6 phosphorylated D-aldohexose derivatives, new C-6 phosphorylated D-aldohexoses derivatives and uses thereof. The method comprises incubating p...  
WO/2008/134828
The present invention provides isolated or essentially pure diterpenoic tetrahydropyran, such as steviol-19-glucuronide, steviol, stevioside and rebaudioside processes for obtaining the same and methods for obtaining stable pharmaceutica...  
WO/2008/134828
The present invention provides isolated or essentially pure diterpenoic tetrahydropyran, such as steviol-19-glucuronide, steviol, stevioside and rebaudioside processes for obtaining the same and methods for obtaining stable pharmaceutica...  
WO/2008/137010
The present invention relates to dentifrices in general and dentifrices free of chemically-derived foaming agents in particular. Particularly, the present invention relates to an all-natural dentifrice (e.g., toothpaste) comprising a con...  
WO/2008/134828
The present invention provides isolated or essentially pure diterpenoic tetrahydropyran, such as steviol-19-glucuronide, steviol, stevioside and rebaudioside processes for obtaining the same and methods for obtaining stable pharmaceutica...  
WO/2008/133766
This invention provides methods, processes, compounds and compositions for modulating the gene expression or secretion of adhesion proteins or their receptors to cure disease, wherein the modulating comprises positive and negative regula...  
WO/2008/133534
Carbohydrate-lipid constructs and their use in inhibiting viral infections in cells.  
WO/2008/131552
Clonal strains of bacteria derived from Pseudopterogorgia elisabethae are capable of making pseudopterosins in in vitro cultures without requiring the presence of other bacteria, algae, or animal cells that are normally present in P. eli...  
WO/2008/131024
Methods of treating glioblastoma and pancreatic cancer are provided by the administration of a therapeutically effective amount of a iodo-hexose compound to a subject in need thereof. The subject invention includes methods of treating gl...  
WO/2008/130263
The invention relates to molecular biology and bioorganic chemistry, in particular to hydrogels based on cross-linked polymers with oligonucleotides, proteins, nucleic acids or any other biologically significant compounds which are immob...  
WO/2008/127086
This invention relates to the use of palm phenolics as natural antioxidants and food preservatives. In particular, the present invention relates to antioxidant compounds derived from a plant material, wherein the said antioxidant compoun...  
WO/2008/126752
A skin-lightening agent containing a novel skin-lightening ingredient as an active ingredient. The active ingredient comprises equol and/or an equol glycoside formed by bonding one or more glycosyl groups to one or more of the hydroxy gr...  
WO/2008/128062
This invention relates to immunogenic compounds which serve as ligands for NKT (natural killer T) cells and to methods of use thereof in modulating immune responses.  
WO/2008/123070
Lactosylceramide can be produced by heat-treating ganglioside GD3 and/or ganglioside GM3 for at 70 to 100˚C and pH 3 to 5 for 30 to 180 minutes, adjusting the pH value of the reaction solution to pH 4.5 to 5.0, and concentrating the rea...  
WO/2008/124821
The present invention is directed to analogs of aminoglycoside compounds as well as their preparation and use as prophylactic or therapeutics against microbial infection.  
WO/2008/118784
The invention relates to derivatives of glycopeptide and lipoglycopeptide antibiotics possessing one or more polyethylene glycol moieties. These compounds are useful as antibiotics for the prevention and/or the treatment of infections an...  
WO/2008/109121
An aqueous, alkaline cleaning composition for use on hard-to-clean soils, encountered in pharmaceutical, personal care, food and cosmetic manufacturing, comprising a source of alkalinity, a biodegradable surfactant system further compris...  
WO/2008/108262
The object is to find a novel mechanism of action of ganglioside GD3 on an immune function and a use application of ganglioside GD3 for medical purposes utilizing the mechanism, and to provide a pharmaceutical agent which is effective fo...  
WO/2008/109735
Disclosed are inactivators of O6-alkylguanine-DNA alkyltransferase (AGT) having the formula:(I) wherein R, R1 and R3 are as described herein. The inactivators are highly water soluble. Also disclosed are pharmaceutical compositions compr...  
WO/2008/108486
The invention provides compounds having excellent cholesterol -lowering effect as well as therapeutic agents, sideration -preventive agents, or evolution-preventive agents for disturbed lipid metabolism, hyperlipidemia, or atherosclerosi...  
WO/2008/108163
Disclosed is a novel gadolinium compound having the following characteristic properties (1) to (4): (1) the compound has a high T1-relaxing capability and enables the imaging even when used in a small quantity; (2) the compound is superi...  
WO/2008/108001
Disclosed are: a novel monogalactosyldiacylglycerol or digalactosyldiacylglycerol compound or a derivative thereof; a process for production of the compound or the derivative; and a food containing the compound.  
WO/2008/109735
Disclosed are inactivators of O6-alkylguanine-DNA alkyltransferase (AGT) having the formula:(I) wherein R, R1 and R3 are as described herein. The inactivators are highly water soluble. Also disclosed are pharmaceutical compositions compr...  
WO/2008/104486
The present invention refers to diagnostically or radiotherapeutically useful compounds which are able to selectively bind to lectins, having formula (I) wherein R, R', R1, R2 and R3 are as defined in the specification; the process for t...  
WO/2008/102669
Disclosed is a novel sugar-linked chlorin derivative which is useful as a substance for photo-dynamic therapy, is stable, and can act as a photosensitizing substance having high phototoxicity even when used in a small quantity. Also disc...  
WO/2008/099560
[PROBLEMS] To provide a simple process by which 5-deoxy-L-arabinose can be efficiently produced. [MEANS FOR SOLVING PROBLEMS] The process includes a step in which a compound represented by the formula (5) is hydrolyzed to obtain an aldos...  
WO/2008/096904
Disclosed are: a compound which can impart a high accumulation property in the blood, high stability in the blood and excellent target cell tropism to a substance of interest; a complex of the compound and a substance of interest; and an...  
WO/2008/096239
This invention pertains to gaseous analytes sensor devices comprising organic thin film transistor and, in particular, sensors able to perform the enantiomeric discrimination of gaseous analytes. The organic thin films are characterized ...  
WO/2008/096028
The present invention provides compounds characterised by the formula (l), where each of the substituent radicals is described in the report. The invention also describes the use of said compounds in the treatment of various diseases, in...  
WO/2008/096880
It is intended to develop a method of effectively synthesizing a glycolipid that has never been established so far. Thus, a method for synthesizing a glycolipid is provided. This method comprises the following steps: (a) the step wherein...  
WO/2008/092690
The present invention relates to paromamine-based compounds according to formula (I) having selective antimicrobial activity directed at ribosomal 16S RNA. Furthermore, the invention is directed to the use of said compounds for preparing...  
WO/2008/093678
[PROBLEMS] To provide: a novel agent having an inhibitory activity on hyaluronidase; and an anti-aging agent for the skin, an anti-inflammatory agent and others each of which comprises the agent. [MEANS FOR SOLVING PROBLEMS] Disclosed is...  
WO/2008/092690
The present invention relates to paromamine-based compounds according to formula (I) having selective antimicrobial activity directed at ribosomal 16S RNA. Furthermore, the invention is directed to the use of said compounds for preparing...  
WO/2008/089602
The present invention provides aminoside tetracyclic anthraquinones represented by formula I or II, wherein the piptides are introduced to connect tetracyclic anthraquinones and fatty acid saturated or unsaturated in order to make the an...  
WO/2008/088047
Disclosed is a method for producing a glycoside of a flavonoid, which comprises the step of reacting the flavonoid and a sugar donor with an enzymatic agent having a glycosylation activity and derived from a bacterium belonging to the ge...  
WO/2008/088806
Compounds, compositions and methods for the treatment of HIV/HSP/HPV, in particular, compositions and methods for a 3 part combination therapy for HIV/HSV/HPV, comprising a viral attachment inhibitor, a viral sequence integration inhibit...  
WO/2008/086857
5-[4-(2-Methyl-phenyl)-3-hydroxy-4H-[1,2,4]triazol-5-yl]-2,4 -dihydroxy-Λ/- methyl-Λ/-butyl-benzamide is an HSP90 inhibitor and can be used for producing a medicament for treating diseases in which the inhibition, regulation and/or mod...  
WO/2008/089403
The invention provides methods for the synthesis of oligosaccharides comprising an aminooxy group. The invention further provides oligosaccharides comprising an aminooxy group, methods for coupling oligosaccharides comprising an aminooxy...  
WO/2008/089403
The invention provides methods for the synthesis of oligosaccharides comprising an aminooxy group. The invention further provides oligosaccharides comprising an aminooxy group, methods for coupling oligosaccharides comprising an aminooxy...  
WO/2008/083461
There is provided a method of producing a plant composition comprising dehydrosoyasaponin I (D-I), the method comprising the steps of extracting a plant flour with a solvent capable of extracting soyasaponins to produce an extract, and t...  
WO/2008/082156
Disclosed are novel α-galactosylceramide derivatives, pharmaceutically acceptable salts thereof, preparation methods thereof, and pharmaceutical compositions for use in an immune adjuvant containing the same as an active ingredient. The...  
WO/2008/078362
An antitumor agent containing at least one compound selected from the group consisting of nerigoside, oleandrigenin, sarmentoside, oleaside A, oleandrin, 8β-hydroxy odoroside A, narciclasine, trans-dihydronarciclasine and bisdeoxynarcic...  

Matches 451 - 500 out of 6,401