Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 451 - 500 out of 6,433

Document Document Title
WO/2009/060086
The present invention relates to compounds consisting of glycolipids covalently bound to an antigen or a drug via a linker. The said compounds are able to induce a stronger immune response than a composition comprising separated glycolip...  
WO/2009/060305
The invention provides analogs of alpha-galactosyl ceramide that increase the immune response elicited by various antigens. It also provides methods of using such compounds to increase the effectiveness of vaccines.  
WO/2009/060086
The present invention relates to compounds consisting of glycolipids covalently bound to an antigen or a drug via a linker. The said compounds are able to induce a stronger immune response than a composition comprising separated glycolip...  
WO/2009/055677
Synthetically-derived S,S-heterodisubstituted disulfides that exhibit potent in vitro antibacterial activity against a variety of bacteria, including Staphylococcus aureus, methicillin-resistant Staphylococcus aureus and Francisella tula...  
WO/2009/049428
Particular naturally occurring glycosylated acyl-flavonols, e.g. montbretm A (of the formula below wherein R1, R2, R3, R5, R5', and R7 is OH each, X is β-D-glucopyranosyl), are now shown to be effective mammalian α-amylase inhibitors S...  
WO/2009/049370
The invention relates to novel compounds that have utility as inhibitors of heparan sulfate-binding proteins; compositions comprising the compounds, and use of the compounds and compositions thereof for the antiangiogenic, antimetastatic...  
WO/2009/052088
Fire extinguishing compositions and methods of extinguishing a fire comprising compounds of formula (I) where Rf is a fluorocarbon group. The compounds and compositions described herein are useful as intermediates in the preparation of o...  
WO/2009/048343
The invention relates to methods for effecting qualitative and quantitative changes in the functional moieties expressed at the surface of cells and multi-cellular structures, and functional lipid constructs for use in such methods. In p...  
WO/2009/047792
The invention provides carbohydrate based compounds of formula (I), methods of preparation, and compositions useful for modulating signaling through Toll -like receptors. The methods involve contacting a TLR -express ing cell with a carb...  
WO/2009/047792
The invention provides carbohydrate based compounds of formula (I), methods of preparation, and compositions useful for modulating signaling through Toll -like receptors. The methods involve contacting a TLR -express ing cell with a carb...  
WO/2009/044886
The invention aims to provide a process for producing 1,2,3-tri-O-acetyl-5-deoxyribofuranose by an industrially suitable means. The invention provides a process for the production of 1,2,3-tri-O-acetyl-5-deoxyribofuranse which comprises ...  
WO/2009/038978
Steviol glycoside isomers are provided having the formula (II): wherein R1may be hydrogen, 1-β-D-glucopyranosyl, or 2-(1-β-D-glucopyranosyl)-1-β-D- glucopyranosyl, and R2 may be hydrogen, 1-β-D-glucopyranosyl, 2-(1-β-D-glucopyranosy...  
WO/2009/036754
The invention relates to a composition having the general structure (formula), wherein R1 is a hydrophobic group, R2 is hydrogen (H), a cation or an alkyl ester, R3 is hydrogen (H) or a group that can be converted into the hydroxy group ...  
WO/2009/038978
Steviol glycoside isomers are provided having the formula (II): wherein R1may be hydrogen, 1-β-D-glucopyranosyl, or 2-(1-β-D-glucopyranosyl)-1-β-D- glucopyranosyl, and R2 may be hydrogen, 1-β-D-glucopyranosyl, 2-(1-β-D-glucopyranosy...  
WO/2009/035107
Disclosed is a transformant produced by introducing a keto reductase gene involved in the biosynthesis of L-epivancosamine into a ray fungus originally capable of producing daunorubicin. Also disclosed is a method for efficiently produci...  
WO/2009/030073
Provided is a dTDP-β-D-fucofuranose, which is also referred to as dTDP-β-6-deoxy-D-galactofuranose. The dTDP-β-D-fucofuranose is synthesized by using reductase Fcf1 and mutase Fcf2 in the gram-negative bacteria. Also provided are the ...  
WO/2009/016647
The present invention provides novel pyrrolo[2,1-c][1, 4]benzodiazepine- glycoside prodrug of general formula (1a-b), useful as selective anticancer agents. The present invention also provides a process for the preparation of novel pyrro...  
WO/2009/014101
Disclosed is a sulfoquinovosyl acyl propanediol derivative represented by the general formula (I) or a pharmaceutically acceptable salt thereof. (I) wherein R1 represents an acyl residue of a fatty acid; and M represents a hydrogen ion o...  
WO/2009/014970
Methods of synthesizing sodium glucose co-transporter 2 inhibitors, as well as compounds useful therein, are disclosed. Particular inhibitors are compounds of formula (I).  
WO/2009/004899
It is intended to provide a novel sialidase inhibitor capable of inhibiting the activity of sialidase present in Trypanosoma cruzi or the like. An N-acylneuraminic acid derivative in which an aromatic ring has been introduced at the 9-po...  
WO/2009/005129
Disclosed are: a non-digestible hydroxypropyl starch hydrolysate which can be used as a novel water-soluble dietary fiber; a method for producing the non-digestible hydroxypropyl starch hydrolysate; and a beverage or food comprising the ...  
WO/2008/151615
The invention relates to a method for producing biosurfactants, according to which micro-organisms producing biosurfactants are moved in a nutrient substrate. According to the invention, the nutrient substrate is used in excess and a mec...  
WO/2008/153394
The present invention relates to compounds according to formula (I) : wherein R2 is absent or a linking moiety and R3 is selected from the group consisting of anti- inflammatory agents and pharmaceutically acceptable salts thereof, pharm...  
WO/2008/153394
The present invention relates to compounds according to formula (I) : wherein R2 is absent or a linking moiety and R3 is selected from the group consisting of anti- inflammatory agents and pharmaceutically acceptable salts thereof, pharm...  
WO/2008/151615
The invention relates to a method for producing biosurfactants, according to which micro-organisms producing biosurfactants are moved in a nutrient substrate. According to the invention, the nutrient substrate is used in excess and a mec...  
WO/2008/146917
Compounds represented by the general formula (1) [wherein A is aryl; R1 is N-(optionally substituted C1-6 alkyl)-N-(optionally substituted C1-6 alkyl)amino-C1-6 alkyl; R2 is hydrogen or optionally substituted C1-6 alkyl; R3 is optionally...  
WO/2008/146919
Disclosed is a compound represented by the formula (I) or a pharmacologically acceptable salt or solvate thereof [in the formula (I), A represents an aryl group and R1 represents a 5- or 6-membered monocyclic heterocyclic group, or A rep...  
WO/2008/147725
Exemplary embodiments of this invention encompass a method for purifying a substantially crude stevioside, methods for preparing polymorphic and amorphous forms of stevioside, and the polymorphic and amorphous forms prepared therefrom.  
WO/2008/143677
Stable solid, crystalline forms of elsamitrucin salts are provided that are useful in preparing anti-neoplastic parenteral formulations. Also provided are methods for treating neoplastic diseases in humans using parenteral formulations t...  
WO/2008/142155
The present invention concerns a method for preparing C-6 phosphorylated D- aldohexoses and C-6 phosphorylated D-aldohexose derivatives, new C-6 phosphorylated D-aldohexoses derivatives and uses thereof. The method comprises incubating p...  
WO/2008/142155
The present invention concerns a method for preparing C-6 phosphorylated D- aldohexoses and C-6 phosphorylated D-aldohexose derivatives, new C-6 phosphorylated D-aldohexoses derivatives and uses thereof. The method comprises incubating p...  
WO/2008/134828
The present invention provides isolated or essentially pure diterpenoic tetrahydropyran, such as steviol-19-glucuronide, steviol, stevioside and rebaudioside processes for obtaining the same and methods for obtaining stable pharmaceutica...  
WO/2008/134828
The present invention provides isolated or essentially pure diterpenoic tetrahydropyran, such as steviol-19-glucuronide, steviol, stevioside and rebaudioside processes for obtaining the same and methods for obtaining stable pharmaceutica...  
WO/2008/137010
The present invention relates to dentifrices in general and dentifrices free of chemically-derived foaming agents in particular. Particularly, the present invention relates to an all-natural dentifrice (e.g., toothpaste) comprising a con...  
WO/2008/134828
The present invention provides isolated or essentially pure diterpenoic tetrahydropyran, such as steviol-19-glucuronide, steviol, stevioside and rebaudioside processes for obtaining the same and methods for obtaining stable pharmaceutica...  
WO/2008/133766
This invention provides methods, processes, compounds and compositions for modulating the gene expression or secretion of adhesion proteins or their receptors to cure disease, wherein the modulating comprises positive and negative regula...  
WO/2008/133534
Carbohydrate-lipid constructs and their use in inhibiting viral infections in cells.  
WO/2008/131552
Clonal strains of bacteria derived from Pseudopterogorgia elisabethae are capable of making pseudopterosins in in vitro cultures without requiring the presence of other bacteria, algae, or animal cells that are normally present in P. eli...  
WO/2008/131024
Methods of treating glioblastoma and pancreatic cancer are provided by the administration of a therapeutically effective amount of a iodo-hexose compound to a subject in need thereof. The subject invention includes methods of treating gl...  
WO/2008/130263
The invention relates to molecular biology and bioorganic chemistry, in particular to hydrogels based on cross-linked polymers with oligonucleotides, proteins, nucleic acids or any other biologically significant compounds which are immob...  
WO/2008/127086
This invention relates to the use of palm phenolics as natural antioxidants and food preservatives. In particular, the present invention relates to antioxidant compounds derived from a plant material, wherein the said antioxidant compoun...  
WO/2008/126752
A skin-lightening agent containing a novel skin-lightening ingredient as an active ingredient. The active ingredient comprises equol and/or an equol glycoside formed by bonding one or more glycosyl groups to one or more of the hydroxy gr...  
WO/2008/128062
This invention relates to immunogenic compounds which serve as ligands for NKT (natural killer T) cells and to methods of use thereof in modulating immune responses.  
WO/2008/123070
Lactosylceramide can be produced by heat-treating ganglioside GD3 and/or ganglioside GM3 for at 70 to 100˚C and pH 3 to 5 for 30 to 180 minutes, adjusting the pH value of the reaction solution to pH 4.5 to 5.0, and concentrating the rea...  
WO/2008/124821
The present invention is directed to analogs of aminoglycoside compounds as well as their preparation and use as prophylactic or therapeutics against microbial infection.  
WO/2008/118784
The invention relates to derivatives of glycopeptide and lipoglycopeptide antibiotics possessing one or more polyethylene glycol moieties. These compounds are useful as antibiotics for the prevention and/or the treatment of infections an...  
WO/2008/109121
An aqueous, alkaline cleaning composition for use on hard-to-clean soils, encountered in pharmaceutical, personal care, food and cosmetic manufacturing, comprising a source of alkalinity, a biodegradable surfactant system further compris...  
WO/2008/108262
The object is to find a novel mechanism of action of ganglioside GD3 on an immune function and a use application of ganglioside GD3 for medical purposes utilizing the mechanism, and to provide a pharmaceutical agent which is effective fo...  
WO/2008/109735
Disclosed are inactivators of O6-alkylguanine-DNA alkyltransferase (AGT) having the formula:(I) wherein R, R1 and R3 are as described herein. The inactivators are highly water soluble. Also disclosed are pharmaceutical compositions compr...  
WO/2008/108486
The invention provides compounds having excellent cholesterol -lowering effect as well as therapeutic agents, sideration -preventive agents, or evolution-preventive agents for disturbed lipid metabolism, hyperlipidemia, or atherosclerosi...  

Matches 451 - 500 out of 6,433