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Matches 501 - 550 out of 6,449

Document Document Title
WO/2008/123070A1
Lactosylceramide can be produced by heat-treating ganglioside GD3 and/or ganglioside GM3 for at 70 to 100˚C and pH 3 to 5 for 30 to 180 minutes, adjusting the pH value of the reaction solution to pH 4.5 to 5.0, and concentrating the rea...  
WO/2008/124821A1
The present invention is directed to analogs of aminoglycoside compounds as well as their preparation and use as prophylactic or therapeutics against microbial infection.  
WO/2008/118784A1
The invention relates to derivatives of glycopeptide and lipoglycopeptide antibiotics possessing one or more polyethylene glycol moieties. These compounds are useful as antibiotics for the prevention and/or the treatment of infections an...  
WO/2008/109121A1
An aqueous, alkaline cleaning composition for use on hard-to-clean soils, encountered in pharmaceutical, personal care, food and cosmetic manufacturing, comprising a source of alkalinity, a biodegradable surfactant system further compris...  
WO/2008/108262A1
The object is to find a novel mechanism of action of ganglioside GD3 on an immune function and a use application of ganglioside GD3 for medical purposes utilizing the mechanism, and to provide a pharmaceutical agent which is effective fo...  
WO/2008/109735A3
Disclosed are inactivators of O6-alkylguanine-DNA alkyltransferase (AGT) having the formula:(I) wherein R, R1 and R3 are as described herein. The inactivators are highly water soluble. Also disclosed are pharmaceutical compositions compr...  
WO/2008/108486A1
The invention provides compounds having excellent cholesterol -lowering effect as well as therapeutic agents, sideration -preventive agents, or evolution-preventive agents for disturbed lipid metabolism, hyperlipidemia, or atherosclerosi...  
WO/2008/108163A1
Disclosed is a novel gadolinium compound having the following characteristic properties (1) to (4): (1) the compound has a high T1-relaxing capability and enables the imaging even when used in a small quantity; (2) the compound is superi...  
WO/2008/108001A1
Disclosed are: a novel monogalactosyldiacylglycerol or digalactosyldiacylglycerol compound or a derivative thereof; a process for production of the compound or the derivative; and a food containing the compound.  
WO/2008/109735A2
Disclosed are inactivators of O6-alkylguanine-DNA alkyltransferase (AGT) having the formula:(I) wherein R, R1 and R3 are as described herein. The inactivators are highly water soluble. Also disclosed are pharmaceutical compositions compr...  
WO/2008/104486A1
The present invention refers to diagnostically or radiotherapeutically useful compounds which are able to selectively bind to lectins, having formula (I) wherein R, R', R1, R2 and R3 are as defined in the specification; the process for t...  
WO/2008/102669A1
Disclosed is a novel sugar-linked chlorin derivative which is useful as a substance for photo-dynamic therapy, is stable, and can act as a photosensitizing substance having high phototoxicity even when used in a small quantity. Also disc...  
WO/2008/099560A1
[PROBLEMS] To provide a simple process by which 5-deoxy-L-arabinose can be efficiently produced. [MEANS FOR SOLVING PROBLEMS] The process includes a step in which a compound represented by the formula (5) is hydrolyzed to obtain an aldos...  
WO/2008/096904A1
Disclosed are: a compound which can impart a high accumulation property in the blood, high stability in the blood and excellent target cell tropism to a substance of interest; a complex of the compound and a substance of interest; and an...  
WO/2008/096239A1
This invention pertains to gaseous analytes sensor devices comprising organic thin film transistor and, in particular, sensors able to perform the enantiomeric discrimination of gaseous analytes. The organic thin films are characterized ...  
WO/2008/096028A1
The present invention provides compounds characterised by the formula (l), where each of the substituent radicals is described in the report. The invention also describes the use of said compounds in the treatment of various diseases, in...  
WO/2008/096880A1
It is intended to develop a method of effectively synthesizing a glycolipid that has never been established so far. Thus, a method for synthesizing a glycolipid is provided. This method comprises the following steps: (a) the step wherein...  
WO/2008/092690A8
The present invention relates to paromamine-based compounds according to formula (I) having selective antimicrobial activity directed at ribosomal 16S RNA. Furthermore, the invention is directed to the use of said compounds for preparing...  
WO/2008/093678A1
[PROBLEMS] To provide: a novel agent having an inhibitory activity on hyaluronidase; and an anti-aging agent for the skin, an anti-inflammatory agent and others each of which comprises the agent. [MEANS FOR SOLVING PROBLEMS] Disclosed is...  
WO/2008/092690A1
The present invention relates to paromamine-based compounds according to formula (I) having selective antimicrobial activity directed at ribosomal 16S RNA. Furthermore, the invention is directed to the use of said compounds for preparing...  
WO/2008/089602A1
The present invention provides aminoside tetracyclic anthraquinones represented by formula I or II, wherein the piptides are introduced to connect tetracyclic anthraquinones and fatty acid saturated or unsaturated in order to make the an...  
WO/2008/088047A1
Disclosed is a method for producing a glycoside of a flavonoid, which comprises the step of reacting the flavonoid and a sugar donor with an enzymatic agent having a glycosylation activity and derived from a bacterium belonging to the ge...  
WO/2008/088806A1
Compounds, compositions and methods for the treatment of HIV/HSP/HPV, in particular, compositions and methods for a 3 part combination therapy for HIV/HSV/HPV, comprising a viral attachment inhibitor, a viral sequence integration inhibit...  
WO/2008/086857A1
5-[4-(2-Methyl-phenyl)-3-hydroxy-4H-[1,2,4]triazol-5-yl]-2,4 -dihydroxy-Λ/- methyl-Λ/-butyl-benzamide is an HSP90 inhibitor and can be used for producing a medicament for treating diseases in which the inhibition, regulation and/or mod...  
WO/2008/089403A3
The invention provides methods for the synthesis of oligosaccharides comprising an aminooxy group. The invention further provides oligosaccharides comprising an aminooxy group, methods for coupling oligosaccharides comprising an aminooxy...  
WO/2008/089403A2
The invention provides methods for the synthesis of oligosaccharides comprising an aminooxy group. The invention further provides oligosaccharides comprising an aminooxy group, methods for coupling oligosaccharides comprising an aminooxy...  
WO/2008/083461A1
There is provided a method of producing a plant composition comprising dehydrosoyasaponin I (D-I), the method comprising the steps of extracting a plant flour with a solvent capable of extracting soyasaponins to produce an extract, and t...  
WO/2008/082156A1
Disclosed are novel α-galactosylceramide derivatives, pharmaceutically acceptable salts thereof, preparation methods thereof, and pharmaceutical compositions for use in an immune adjuvant containing the same as an active ingredient. The...  
WO/2008/078362A1
An antitumor agent containing at least one compound selected from the group consisting of nerigoside, oleandrigenin, sarmentoside, oleaside A, oleandrin, 8β-hydroxy odoroside A, narciclasine, trans-dihydronarciclasine and bisdeoxynarcic...  
WO/2008/075983A2
The invention relates to compounds which are immunomodulatory compounds and, in particular, can induce IL-12 secretion. The invention also relates to compositions containing the compounds, precursors, and prodrugs of these compounds, use...  
WO/2008/075983A3
The invention relates to compounds which are immunomodulatory compounds and, in particular, can induce IL-12 secretion. The invention also relates to compositions containing the compounds, precursors, and prodrugs of these compounds, use...  
WO/2008/075959A1
The present invention is in the field of Fabry disease and concerns a pathogenic factor allowing diagnosis of Fabry disease. In particular lyso-ceramide trihexosamide (lyso-CTH) has been found to function as a diagnostic marker for Fabry...  
WO/2008/071009A1
This application relates to micelle-forming poly(ethylene oxide)-block-poly(ester) block copolymers having reactive groups on both the poly(ethylene oxide) block and the poly(ester) block therein. The biodegradability of these copolymers...  
WO/2008/069303A1
Disclosed is a method for producing a β-anomer of a ribofuranose derivative with high selectivity, in high yield, and in an industrially proper manner. Specifically disclosed is a method for producing a ribofuranose derivative, which is...  
WO/2008/067039A2
Colchicine neoglycosides, method for their synthesis and methods for their use are disclosed. The invention provides analogs of colchicine glycosylated to include a sugar moiety on a colchicine scaffold that is generally unglycosylated i...  
WO/2008/067039A3
Colchicine neoglycosides, method for their synthesis and methods for their use are disclosed. The invention provides analogs of colchicine glycosylated to include a sugar moiety on a colchicine scaffold that is generally unglycosylated i...  
WO/2008/062842A1
Disclosed are a sodium salt represented by the average formula (I) below, and a method for producing such a sodium salt. (In the formula, m1, n1, m2 and n2 independently represent 0 or a positive number not more than 2, while satisfying ...  
WO/2008/060378A2
Compounds and methods are provided for obtaining oligosaccharide mimics. More specifically, compounds and methods are described wherein oligosaccharide mimics are obtained by incorporating or substituting in a cyclohexane derivative.  
WO/2008/060632A3
The invention provides substituted 5'-bi- tri- or tetraphosphate ribose analog compounds that act at P2Y receptors, e.g., the P2Y2 receptor, including pharmaceutical compositions; and uses thereof to treat or prevent diseases associated ...  
WO/2008/060378A3
Compounds and methods are provided for obtaining oligosaccharide mimics. More specifically, compounds and methods are described wherein oligosaccharide mimics are obtained by incorporating or substituting in a cyclohexane derivative.  
WO/2008/059035A2
The present invention relates to a novel process for the chemical synthesis of β-(1->6)-linked glucosamine disaccharides of the fomula (1) and (intermediate) compounds relating to the process. According to further aspects the invention ...  
WO/2008/059035A3
The present invention relates to a novel process for the chemical synthesis of β-(1->6)-linked glucosamine disaccharides of the fomula (1) and (intermediate) compounds relating to the process. According to further aspects the invention ...  
WO/2008/054892A2
A composition and method for the preparation of micro-particles of chitin (a naturally occurring polymer of N-acetyl-D-glucosamine), the characterization of chitin micro-particles as an immune adjuvant and the use of chitin micro-particl...  
WO/2008/052077A2
One embodiment of the present inventionis a process of making sucrose-6-ester from sucrose by transesterification in the presence of a solid super acid catalyst such as SO4 2---TiO2/Al2O3 or SO4 2---TiO2. The sucrose-6-acetate is then ch...  
WO/2008/049974A2  
WO/2008/046463A1
The invention relates to the subject matters characterized in the claims, namely metal chelates having a perfluorinated PEG group, a method for the production thereof, and the use thereof, a method for the production thereof, and the use...  
WO/2008/047658A1
An object is to provide a safe and convenient means for preventing or treating a disease in an avian or mammal, particularly a farm animal, specifically to provide a means for preventing or treating an inflammatory disease in a farm anim...  
WO/2008/047249A3
The invention relates to α -galactoceramide analogs, their methods of manufacture, intermediate compounds useful in these methods. It also relates to pharmaceutical compositions containing the α-galactoceramide analogs. The methods of ...  
WO/2008/047174A1
The invention relates to α-galactoceramide analogs, their methods of manufacture, intermediate compounds useful in these methods. It also relates to pharmaceutical compositions containing the α-galactoceramide analogs. The methods of m...  
WO/2008/047249A9
The invention relates to α -galactoceramide analogs, their methods of manufacture, intermediate compounds useful in these methods. It also relates to pharmaceutical compositions containing the α-galactoceramide analogs. The methods of ...  

Matches 501 - 550 out of 6,449