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Patent Searching and Data


Matches 501 - 550 out of 6,401

Document Document Title
WO/2008/075983
The invention relates to compounds which are immunomodulatory compounds and, in particular, can induce IL-12 secretion. The invention also relates to compositions containing the compounds, precursors, and prodrugs of these compounds, use...  
WO/2008/075983
The invention relates to compounds which are immunomodulatory compounds and, in particular, can induce IL-12 secretion. The invention also relates to compositions containing the compounds, precursors, and prodrugs of these compounds, use...  
WO/2008/075959
The present invention is in the field of Fabry disease and concerns a pathogenic factor allowing diagnosis of Fabry disease. In particular lyso-ceramide trihexosamide (lyso-CTH) has been found to function as a diagnostic marker for Fabry...  
WO/2008/071009
This application relates to micelle-forming poly(ethylene oxide)-block-poly(ester) block copolymers having reactive groups on both the poly(ethylene oxide) block and the poly(ester) block therein. The biodegradability of these copolymers...  
WO/2008/069303
Disclosed is a method for producing a β-anomer of a ribofuranose derivative with high selectivity, in high yield, and in an industrially proper manner. Specifically disclosed is a method for producing a ribofuranose derivative, which is...  
WO/2008/067039
Colchicine neoglycosides, method for their synthesis and methods for their use are disclosed. The invention provides analogs of colchicine glycosylated to include a sugar moiety on a colchicine scaffold that is generally unglycosylated i...  
WO/2008/067039
Colchicine neoglycosides, method for their synthesis and methods for their use are disclosed. The invention provides analogs of colchicine glycosylated to include a sugar moiety on a colchicine scaffold that is generally unglycosylated i...  
WO/2008/062842
Disclosed are a sodium salt represented by the average formula (I) below, and a method for producing such a sodium salt. (In the formula, m1, n1, m2 and n2 independently represent 0 or a positive number not more than 2, while satisfying ...  
WO/2008/060378
Compounds and methods are provided for obtaining oligosaccharide mimics. More specifically, compounds and methods are described wherein oligosaccharide mimics are obtained by incorporating or substituting in a cyclohexane derivative.  
WO/2008/060632
The invention provides substituted 5'-bi- tri- or tetraphosphate ribose analog compounds that act at P2Y receptors, e.g., the P2Y2 receptor, including pharmaceutical compositions; and uses thereof to treat or prevent diseases associated ...  
WO/2008/060378
Compounds and methods are provided for obtaining oligosaccharide mimics. More specifically, compounds and methods are described wherein oligosaccharide mimics are obtained by incorporating or substituting in a cyclohexane derivative.  
WO/2008/059035
The present invention relates to a novel process for the chemical synthesis of β-(1->6)-linked glucosamine disaccharides of the fomula (1) and (intermediate) compounds relating to the process. According to further aspects the invention ...  
WO/2008/059035
The present invention relates to a novel process for the chemical synthesis of β-(1->6)-linked glucosamine disaccharides of the fomula (1) and (intermediate) compounds relating to the process. According to further aspects the invention ...  
WO/2008/054892
A composition and method for the preparation of micro-particles of chitin (a naturally occurring polymer of N-acetyl-D-glucosamine), the characterization of chitin micro-particles as an immune adjuvant and the use of chitin micro-particl...  
WO/2008/052077
One embodiment of the present inventionis a process of making sucrose-6-ester from sucrose by transesterification in the presence of a solid super acid catalyst such as SO4 2---TiO2/Al2O3 or SO4 2---TiO2. The sucrose-6-acetate is then ch...  
WO/2008/049974  
WO/2008/046463
The invention relates to the subject matters characterized in the claims, namely metal chelates having a perfluorinated PEG group, a method for the production thereof, and the use thereof, a method for the production thereof, and the use...  
WO/2008/047658
An object is to provide a safe and convenient means for preventing or treating a disease in an avian or mammal, particularly a farm animal, specifically to provide a means for preventing or treating an inflammatory disease in a farm anim...  
WO/2008/047249
The invention relates to α -galactoceramide analogs, their methods of manufacture, intermediate compounds useful in these methods. It also relates to pharmaceutical compositions containing the α-galactoceramide analogs. The methods of ...  
WO/2008/047174
The invention relates to α-galactoceramide analogs, their methods of manufacture, intermediate compounds useful in these methods. It also relates to pharmaceutical compositions containing the α-galactoceramide analogs. The methods of m...  
WO/2008/047249
The invention relates to α -galactoceramide analogs, their methods of manufacture, intermediate compounds useful in these methods. It also relates to pharmaceutical compositions containing the α-galactoceramide analogs. The methods of ...  
WO/2008/047249
The invention relates to α -galactoceramide analogs, their methods of manufacture, intermediate compounds useful in these methods. It also relates to pharmaceutical compositions containing the α-galactoceramide analogs. The methods of ...  
WO/2008/037923
The invention relates to new compounds of 5-thioxilose, preferably derivatives of the 5-thioxilopyranose type, and to a method for preparing the same and their use as the active ingredient of drugs mainly intended for treating or prevent...  
WO/2008/039492
Provided are polymorphic forms of valrubicin and processes for their preparation.  
WO/2008/039492
Provided are polymorphic forms of valrubicin and processes for their preparation.  
WO/2008/032817
It is intended to provide a novel sugar chain which has an activity against Helicobacter pylori and a method of producing the same. Namely, a compound represented by the following general formula (1) is provided: (1)wherein Ac represents...  
WO/2008/029294
The present invention relates to methods of synthesizing anthracycline derivatives. Among other advantages, these methods offer simple and efficient manipulation of substituents on the sugar ring of anthracyclines. For example, the C-3 '...  
WO/2008/028667
The present invention relates to adjuvants of the glycolipid type and their uses in pharmaceutical compositions, like in vaccines. In particular, the present invention provides new uses of compounds useful as adjuvants for prophylactic a...  
WO/2008/030121
The invention relates to sweetening compositions obtained from the Luo Han Guo fruit, a member of the Cucurbiticeae family. The compositions are free of bitter-tasting impurities, have a light colour and contain about 16-75% mogroside V ...  
WO/2008/028966
The novel crystalline and polymorphic forms of 1,6-Bis [3-(3-carboxymethylphenyl)-4-(2-α-D-mannopyranosyloxy)-phen yl] hexane have advantageous properties and can be used in pharmaceutical and dermatological compositions.  
WO/2008/030112
The invention relates to methods of preparing compounds of formula (II) wherein Z represents -OR1 or -N(R2)R2a-, where R1 is lower alkylene (C1-C6), R2 is lower alkyl or H and R2a is lower alkylene (C1-C6) or H;Q is absent when R2a is H ...  
WO/2008/028667
The present invention relates to adjuvants of the glycolipid type and their uses in pharmaceutical compositions, like in vaccines. In particular, the present invention provides new uses of compounds useful as adjuvants for prophylactic a...  
WO/2008/029294
The present invention relates to methods of synthesizing anthracycline derivatives. Among other advantages, these methods offer simple and efficient manipulation of substituents on the sugar ring of anthracyclines. For example, the C-3 '...  
WO/2008/028060
This invention provides a method for treating cancer by blocking the migration, metastasis of cancer cells, growth of cancers wherein the cancers comprise breast cancer, leukocyte cancer, liver cancer, ovarian cancer, bladder cancer, pro...  
WO/2008/028060
This invention provides a method for treating cancer by blocking the migration, metastasis of cancer cells, growth of cancers wherein the cancers comprise breast cancer, leukocyte cancer, liver cancer, ovarian cancer, bladder cancer, pro...  
WO/2008/028050
The present invention relates to methods of use of glycosyltransferases and related novel compounds. The invention exploits the reversibility of glycosyltransferases to generate new sugars, unnatural biomolecules and numerous one-pot rea...  
WO/2008/028050
The present invention relates to methods of use of glycosyltransferases and related novel compounds. The invention exploits the reversibility of glycosyltransferases to generate new sugars, unnatural biomolecules and numerous one-pot rea...  
WO/2008/020490
Disclosed is a substance having an ability of inhibiting a testosteron-5α-reductase activity, an ability of inhibiting or reducing the proliferation of a cancer cell, an ability of inhibiting a cyclooxygenase, an ability of inhibiting a...  
WO/2008/018448
At least one kind of a biosurfactant, in particular, a mannosyl alditol lipid (MEL, MML or the like) or a triacyl derivative of the same is used as an active ingredient. Thus, it becomes possible to provide an activator or an anti-aging ...  
WO/2008/016132
Disclosed is a benzyl phenyl glucopyranoside derivative having excellent inhibitory effect on human SGLT1 and/or SGLT2 activity. Specifically disclosed is a compound represented by the general formula (I) or a pharmacologically acceptabl...  
WO/2008/016007
A phthalic acid derivative represented by the general formula (1) has an inhibitory activity on metallo-β-lactamase. Therefore, when used in combination with a β-lactam antibiotic, the derivative can inhibit the deactivation of the β-...  
WO/2008/010324
The invention relates to a fusicoccin derivative and a cell differentiation-inducing agent containing the same as an active ingredient, an anti-hematologic malignancy agent, an antitumor agent, an agent for enhancing an antitumor effect,...  
WO/2008/011588
Bromoglufosfamide and related compounds are useful in the treatment of cancer and other hyperproliferative diseases. Glufosfamide and bromoglufosfamide are synthesized by reacting the corresponding tetracetyl derivatives with MeOH and a ...  
WO/2008/007003
Composition (C) comprising for 100% of its mass: from 0.5% to 30% of one or more alcohols having the formula (IV): R1-OH (IV) wherein R1 represents a saturated or unsaturated, linear or branched aliphatic group, having from 8 to 36 carbo...  
WO/2008/007003
Composition (C) comprising for 100% of its mass: from 0.5% to 30% of one or more alcohols having the formula (IV): R1-OH (IV) wherein R1 represents a saturated or unsaturated, linear or branched aliphatic group, having from 8 to 36 carbo...  
WO/2008/003314
The present invention provides a method of preparing a glycoside of a mono- or diacylglycerol product from a plant material. The method comprises the steps of: (i) optionally milling the plant material, (ii) extracting the optionally mil...  
WO/2007/148631
The object is to provide a composition which can significantly promote the production of an equol. When added to a pharmaceutical agent or a beverage/food, the composition can exerts an effect of preventing a vascular disease because of ...  
WO/2007/145362
It is intended to provide a novel glyceroglycolipid produced by Mycoplasma pneumoniae. This glyceroglycolipid can be used as a diagnostic marker for a disease caused by Mycoplasma pneumoniae.  
WO/2007/143052
Compositions and methods are provided related to Pseudomonas bacteria. The compositions and methods may be used for diagnosis and therapy of medical conditions involving infection with Pseudomonas bacteria. Such infections include Pseudo...  
WO/2007/142150
Disclosed are: a novel aminoglycoside antibiotic which has an excellent anti-bacterial activity against an infection-inducing bacterium, particularly MRSA, and also has low renal toxicity; and a process for production of the antibiotic. ...  

Matches 501 - 550 out of 6,401