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Patent Searching and Data


Matches 501 - 550 out of 13,188

Document Document Title
WO/2014/124245A1
The invention is directed to compositions and methods related to proteins that are physically associated with ceramide-like glycolipids for use as activators of NKT cells. The compositions and methods of the present invention are useful ...  
WO/2014/070991A3
Provided herein are E-selectin antagonist therapeutic agents and improvements thereto and compositions comprising these E-selectin antagonists. Methods are also provided for using these E-selectin antagonist therapeutic agents to treat a...  
WO/2014/100158A1
The present invention relates to compounds useful for the treatment or prevention of bacteria infections. These compounds have formula (I). The invention also provides pharmaceutically acceptable compositions containing the compounds and...  
WO/2014/100700A1
Disclosed herein are cytoprotective derivatives of avicin D of formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising these derivative compounds. Meth...  
WO/2014/096331A1
The invention relates to a method for making an N-substituted D-mannosamine derivative of the following formula 1 and its salts wherein R1 is a non-electron-withdrawing group,and wherein R2 is -OH or R2 is –NHR3 wherein R3 is a group r...  
WO/2014/096377A1
New hydroxy aliphatic substituted phenyl aminoalkyi ether compounds of formula (I), compositions thereof and their use as a medicament in the treatment of nervous system diseases and/or the treatment of developmental, behavioral and/or m...  
WO/2014/098833A1
Polymorphic and amorphous forms of Rebaudioside X and methods for preparing the same are provided herein. Also provided herein are Rebaudioside X complexes and methods for preparing the same. Sweetener compositions and sweetened composit...  
WO/2014/089226A1
With the rise in resistance to antibiotics such as methicillin, there is a need for new drugs. The invention provides small molecules that inhibit cellular drug targets such as UPPS and FPPS by interacting with binding pockets, thereby p...  
WO/2014/088432A1
The invention relates to sphingoglycolipid analogues and peptide derivatives thereof, which are useful in treating or preventing diseases or such as those relating to infection, atopic disorders, autoimmune diseases or cancer.  
WO/2014/084744A1
The invention relates to dendritic compounds, the use of these compounds as pharmaceuticals, pharmaceutical compositions containing the compounds, processes for preparing the compounds, and methods of treating diseases or conditions in w...  
WO/2014/079300A1
The present invention relates to a method for preparing highly pure doxorubicin. The method comprises the following steps: (1) chromatographing a prepurified doxorubicin solution by using macroporous resin, pre-washing the chromatographe...  
WO/2014/077960A1
The present invention provides carbohydrate-based surfactants and methods for producing the same. Methods for producing carbohydrate -based surfactants include using a glycosylation promoter to link a carbohydrate or its derivative to a ...  
WO/2014/076425A1
The subject matter of the invention is a method for obtaining polyphenols from a vegetable raw material containing same, characterised in that it comprises at least the following steps: - optionally drying the raw material containing the...  
WO/2014/070988A1
Compounds and methods are provided for enhancing the oral availability of glycomimetics. More specifically, in an embodiment, a glycomimetic is modified to decrease the polar surface area of the glycomimetic in order to increase absorpti...  
WO/2014/070991A2
Provided herein are E-selectin antagonist therapeutic agents and improvements thereto and compositions comprising these E-selectin antagonists. Methods are also provided for using these E-selectin antagonist therapeutic agents to treat a...  
WO/2014/067995A1
The present invention relates to a method of preparation of α-galactosyl ceramides compounds of formula (I) comprising a step a) of glycosylation of a compound of formula (II) with a compound of formula (III).  
WO/2014/070709A1
Adjuvants comprising chitosan cross-linked with, an aldehyde or mannosylated chitosan are provided herein. Methods of making the adjuvants and methods of combining or linking the adjuvants with antigens are also provided. The adjuvant-an...  
WO/2014/066274A1
The present invention related to low-chloride alkylated cyclodextrin compositions, along with processes for preparing and using the same. The processes of the present invention provide alkylated cyclodextrins with low levels of drug-degr...  
WO/2014/064161A1
The present invention concerns a process for the purification of tritium markedparomomycin ([3H]paromomycin), highly pure tritiated paromomycin obtained by said process and a composition comprising said paromomycin. The present invention...  
WO/2014/063441A1
The present invention relates to a use of a triterpene derivative of formula (I) for producing drugs which can be used for the prevention or treatment of influenza diseases, wherein the substituents are as defined in the specification. T...  
WO/2014/059740A1
Disclosed are a compound as shown in formula (I) and pharmaceutically acceptable salts thereof. R1, R2, R3, R4, R5, W, and n are defined as in the description of the present application.  
WO/2014/060408A1
The invention relates to compounds of the general formula (I) in which R1 is a hydrogen atom, a hydroxy or methoxy group, a halogen atom, or an NO2 group; R2 is a hydrogen atom, a hydroxy or methoxy group, or an acyl or aroyl group; R3 i...  
WO/2014/056038A1
The present disclosure provides a compound of the following formula, racemates, enantiomers, prodrugs and salts thereof: Formula (I). Also provided is the use of these compounds for the treatment of ischemia and reperfusion injuries. Fur...  
WO/2014/059220A1
The invention provides, inter alia, immunoinhibitory glycosphingolipids and immunoinhibitory alpha-galactosylceramides and compositions and preparations thereof, and methods of use thereof including in the treatment of conditions charact...  
WO/2014/055474A1
The present invention relates to compounds useful for the treatment or prevention of bacteria infections. The invention also provides pharmaceutically acceptable compositions containing the compounds and methods of using the compositions...  
WO/2014/054601A1
The present invention aims at providing: a sugar derivative capable of producing a blue fluorescent color, which can be used for the imaging of a cell or an intracellular molecule; and a method for imaging a cell using the derivative. Th...  
WO/2014/053603A1
The invention relates to compounds of formula (I); wherein A and L are as defined in the description. The invention also relates to immunogens obtained from said compounds, and to antibodies raised against said immunogens. The compounds ...  
WO/2014/052457A1
Sweetener compositions comprising particular glycoside blends are described in this paper. The glycoside blends comprise any or all of rebaudioside A, rebaudioside B, and rebaudioside D together with stevioside in various proportions. Th...  
WO/2014/048439A1
The invention relates to a method for producing a glycoconjugate comprising an oligosaccharide part covalently linked to a non-sugar moiety selected from the group consisting of amino acids, peptides, proteins, lipids, longer alkyl group...  
WO/2014/044645A1
The patent application relates to compounds of formula (I) below: formula (I) to a process for preparing them and to the therapeutic use thereof.  
WO/2014/042087A1
Provided is a diarylethene compound having excellent water solubility. The diarylethene compound is represented by formula (I). [In formula (I), Sg is a monovalent saccharide residue formed by removing a hydroxy group from a saccharide c...  
WO/2014/043708A1
Methods and compositions of the invention relate to the enhancement of specific immunotherapies in cancer treatment. In particular, aspects of the invention relate to novel approaches to boost immune function using a complex carbohydrate...  
WO/2014/034190A1
The present invention is a radiation-sensitive resin composition, which contains an acid-cleavable group-containing polymer, a radiation-sensitive acid generator and a solvent, and wherein the radiation-sensitive acid generator contains ...  
WO/2014/003950A3
Nutritional supplements are described comprising selenium containing nucleosides. Methods of making the nutritional supplements and using the nutritional supplements are also described.  
WO/2014/027203A1
An imaging agent comprising a conjugate of an oligosaccharide moiety with an imaging moiety. The oligosaccharide is Lewis A or Lewis B or a mimetic thereof, or a pharmaceutically acceptable salt or PEGylated form of Lewis A or Lewis B or...  
WO/2014/020285A1
The invention concerns novel glycosidase substrates of formula (I); in which R0, R1, R2, R3 and R4 are as defined in claim 1, and a method for detecting the presence of a catalytically active glycosidase by means of one of said substrates.  
WO/2014/021464A1
The purpose of the present invention is to provide: a novel KRN7000 analogue which is expected to have an immunosuppressive effect and is biased toward type-Th2;and a medicinal agent comprising the KRN7000 analogue. A compound represente...  
WO/2014/016361A1
The present invention relates to multimeric mannosides, a process for preparing the same and their uses in medicine for treating Escherichia Coli infections. Exemplary compounds are:  
WO/2014/016374A1
The present invention provides methods for purifying at least one saponin in a solution comprising the steps of: (a) providing at least one saponin in a first solvent comprising a solubilizing component; (b) replacing at least a portion ...  
WO/2014/017928A1
This invention relates to sphingoglycolipid analogues, compositions comprising these compounds, processes for preparing the compounds, and methods of treating or preventing diseases or conditions using the compounds, such as diseases or ...  
WO/2014/016317A1
The present invention relates to the synthesis of GPI-related surface antigens of the parasite Toxoplasma gondii (T. gondii) and the resulting products obtained. These synthetic compounds are suitable for diagnosis of toxoplasmosis, as w...  
WO/2014/013495A1
The present invention relates to amphiphilic aminoglycoside (AG) derivatives, especially derivatives of tobramycin, kanamycin A and paromomycin comprising hydrophobic side chains linked to the AG moiety by various linkers. These novel de...  
WO/2013/114223A3
The present invention relates to a process for producing a syrup which is rich in maltitol. The process is comprising the successive steps of liquefaction of a starch milk and saccharification of the liquefied starch milk in the presence...  
WO/2014/007362A1
Provided is a method whereby a target cyclic macrolide compound can be separated without using a silver compound even from a mixture that contains a compound having a double bond similar to the target cyclic macrolide compound. The metho...  
WO/2014/003950A2
Nutritional supplements are described comprising selenium containing nucleosides. Methods of making the nutritional supplements and using the nutritional supplements are also described.  
WO/2014/001204A1
This invention relates to carbamate-containing or thiocarbamate-containing galacto-pyranosyl compounds useful as therapeutic agents and being represented by the structural formula (II), wherein: X is O or S, R is selected from the group ...  
WO/2013/189237A1
Disclosed are a novel andrographolide derivative and analogue as well as a preparation method of the novel andrographolide derivative and analogue and an application to the treatment, the prevention and the relief on human viruses and ne...  
WO/2013/191550A1
The invention relates to the field of chemical derivatization. In particular, it relates to modified aminoglycosides, such as antibiotics, and methods for producing them. Provided is a method for the regioselective diazotation of a desox...  
WO/2013/191549A1
The invention relates to the field of carbohydrate chemistry. Provided is a process for the regioselective oxidation of a single secondary hydroxy function of a carbohydrate substrate comprising two or more secondary hydroxy functions, c...  
WO/2013/190103A1
The invention relates to a sialic acid derivative of formula (I), wherein the symbols have the meanings specified in the description, which is suitable for linking to a cargo for regulating metabolic processes, immune reactions, immuniza...  

Matches 501 - 550 out of 13,188