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Matches 551 - 600 out of 6,434

Document Document Title
WO/2008/028667
The present invention relates to adjuvants of the glycolipid type and their uses in pharmaceutical compositions, like in vaccines. In particular, the present invention provides new uses of compounds useful as adjuvants for prophylactic a...  
WO/2008/030121
The invention relates to sweetening compositions obtained from the Luo Han Guo fruit, a member of the Cucurbiticeae family. The compositions are free of bitter-tasting impurities, have a light colour and contain about 16-75% mogroside V ...  
WO/2008/028966
The novel crystalline and polymorphic forms of 1,6-Bis [3-(3-carboxymethylphenyl)-4-(2-α-D-mannopyranosyloxy)-phen yl] hexane have advantageous properties and can be used in pharmaceutical and dermatological compositions.  
WO/2008/030112
The invention relates to methods of preparing compounds of formula (II) wherein Z represents -OR1 or -N(R2)R2a-, where R1 is lower alkylene (C1-C6), R2 is lower alkyl or H and R2a is lower alkylene (C1-C6) or H;Q is absent when R2a is H ...  
WO/2008/028667
The present invention relates to adjuvants of the glycolipid type and their uses in pharmaceutical compositions, like in vaccines. In particular, the present invention provides new uses of compounds useful as adjuvants for prophylactic a...  
WO/2008/029294
The present invention relates to methods of synthesizing anthracycline derivatives. Among other advantages, these methods offer simple and efficient manipulation of substituents on the sugar ring of anthracyclines. For example, the C-3 '...  
WO/2008/028060
This invention provides a method for treating cancer by blocking the migration, metastasis of cancer cells, growth of cancers wherein the cancers comprise breast cancer, leukocyte cancer, liver cancer, ovarian cancer, bladder cancer, pro...  
WO/2008/028060
This invention provides a method for treating cancer by blocking the migration, metastasis of cancer cells, growth of cancers wherein the cancers comprise breast cancer, leukocyte cancer, liver cancer, ovarian cancer, bladder cancer, pro...  
WO/2008/028050
The present invention relates to methods of use of glycosyltransferases and related novel compounds. The invention exploits the reversibility of glycosyltransferases to generate new sugars, unnatural biomolecules and numerous one-pot rea...  
WO/2008/028050
The present invention relates to methods of use of glycosyltransferases and related novel compounds. The invention exploits the reversibility of glycosyltransferases to generate new sugars, unnatural biomolecules and numerous one-pot rea...  
WO/2008/020490
Disclosed is a substance having an ability of inhibiting a testosteron-5α-reductase activity, an ability of inhibiting or reducing the proliferation of a cancer cell, an ability of inhibiting a cyclooxygenase, an ability of inhibiting a...  
WO/2008/018448
At least one kind of a biosurfactant, in particular, a mannosyl alditol lipid (MEL, MML or the like) or a triacyl derivative of the same is used as an active ingredient. Thus, it becomes possible to provide an activator or an anti-aging ...  
WO/2008/016132
Disclosed is a benzyl phenyl glucopyranoside derivative having excellent inhibitory effect on human SGLT1 and/or SGLT2 activity. Specifically disclosed is a compound represented by the general formula (I) or a pharmacologically acceptabl...  
WO/2008/016007
A phthalic acid derivative represented by the general formula (1) has an inhibitory activity on metallo-β-lactamase. Therefore, when used in combination with a β-lactam antibiotic, the derivative can inhibit the deactivation of the β-...  
WO/2008/010324
The invention relates to a fusicoccin derivative and a cell differentiation-inducing agent containing the same as an active ingredient, an anti-hematologic malignancy agent, an antitumor agent, an agent for enhancing an antitumor effect,...  
WO/2008/011588
Bromoglufosfamide and related compounds are useful in the treatment of cancer and other hyperproliferative diseases. Glufosfamide and bromoglufosfamide are synthesized by reacting the corresponding tetracetyl derivatives with MeOH and a ...  
WO/2008/007003
Composition (C) comprising for 100% of its mass: from 0.5% to 30% of one or more alcohols having the formula (IV): R1-OH (IV) wherein R1 represents a saturated or unsaturated, linear or branched aliphatic group, having from 8 to 36 carbo...  
WO/2008/007003
Composition (C) comprising for 100% of its mass: from 0.5% to 30% of one or more alcohols having the formula (IV): R1-OH (IV) wherein R1 represents a saturated or unsaturated, linear or branched aliphatic group, having from 8 to 36 carbo...  
WO/2008/003314
The present invention provides a method of preparing a glycoside of a mono- or diacylglycerol product from a plant material. The method comprises the steps of: (i) optionally milling the plant material, (ii) extracting the optionally mil...  
WO/2007/148631
The object is to provide a composition which can significantly promote the production of an equol. When added to a pharmaceutical agent or a beverage/food, the composition can exerts an effect of preventing a vascular disease because of ...  
WO/2007/145362
It is intended to provide a novel glyceroglycolipid produced by Mycoplasma pneumoniae. This glyceroglycolipid can be used as a diagnostic marker for a disease caused by Mycoplasma pneumoniae.  
WO/2007/143052
Compositions and methods are provided related to Pseudomonas bacteria. The compositions and methods may be used for diagnosis and therapy of medical conditions involving infection with Pseudomonas bacteria. Such infections include Pseudo...  
WO/2007/142150
Disclosed are: a novel aminoglycoside antibiotic which has an excellent anti-bacterial activity against an infection-inducing bacterium, particularly MRSA, and also has low renal toxicity; and a process for production of the antibiotic. ...  
WO/2007/139556
A method of treating cancer in a subject comprising administering to the subject in need of the treatment a therapeutically effective amount of an alkylating agent such as temozolomide and a substituted anthracycline compound.  
WO/2007/131444
The present invention provides two kinds of new crystallographic form of the compound 3,4',5-trihydroxyl-stilbene-3-beta-D-glucoside, their manufature and medication combination comprising II-crystallographic form or III- crystallographi...  
WO/2007/128480
The present invention relates to thioglycosides and stereoisomeric forms, solvates, hydrates and/or pharmaceutically acceptable salts of these compounds, as well as pharmaceutical compositions containing at least one of these thioglycosi...  
WO/2007/128480
The present invention relates to thioglycosides and stereoisomeric forms, solvates, hydrates and/or pharmaceutically acceptable salts of these compounds, as well as pharmaceutical compositions containing at least one of these thioglycosi...  
WO/2007/126117
The object is to provide a novel phenyl 5-thioglucoside compound which can control IGT (impaired glucose tolerance) by inhibiting the SGLT1 activity and inhibiting the absorption of glucose through a digestive tract. Provided is a phenyl...  
WO/2007/125176
The invention relates to an improved process for the production of a sugar alcohol from the corresponding sugar through catalytic hydrogenation. Especially, the invention relates to a process for reducing the interference of sugar-derive...  
WO/2007/123403
The present invention discloses a therapeutic target for the treatment of cyst ic fibrosis. It was found that inhibition of non-lysosomal glucosylceramidase (GBA2) sufficiently restores chloride current in cells from CF patients carrying...  
WO/2007/124102
The present invention concerns the isolation of phlorizin from plants of the genus Lithocarpus, phlorizin-containing compositions and their uses.  
WO/2007/124102
The present invention concerns the isolation of phlorizin from plants of the genus Lithocarpus, phlorizin-containing compositions and their uses.  
WO/2007/118947
Compounds derived from α-C-phenyl-N-tert-butylnitrone, a process for the preparation thereof and use thereof for the preparation of medicaments for use in preventing or treating oxidative stress-related diseases.  
WO/2007/117500
Processes for the synthesis of lipochitooligosaccharides were developed. A fully acylated oligoglucosamine precursor is prepared and reacted with a glucosamine monomer that has an amine protecting phthaloyl group. With removal of the pht...  
WO/2007/118143
A method for producing isolated limonoid glucoside compounds is disclosed which includes extracting a quantity of defatted citrus seed powder with a solvent, filtering the resulting extract to yield a particle free extract and concentrat...  
WO/2007/117500
Processes for the synthesis of lipochitooligosaccharides were developed. A fully acylated oligoglucosamine precursor is prepared and reacted with a glucosamine monomer that has an amine protecting phthaloyl group. With removal of the pht...  
WO/2007/112567
Archaeal lipid adjuvants are synthesized by chemically coupling various carbohydrates or anionic polar groups to the free hydroxyl(s) of archaeal lipid cores. Chemically stable lipid cores such as saturated archaeol and caldarchaeol are ...  
WO/2007/111214
Disclosed is a novel trehalose compound having a high affinity to an adenosine A3 receptor. The trehalose compound is represented by the general formula (1): (1) wherein X and X’ independently represent a hydrogen atom or the like; Y a...  
WO/2007/107285
The present invention relates to compounds of general formula (I), wherein R1-R4 are as defined in the description, to processes for their preparation and to their use as medicaments. The compounds of formula (I) inhibit the effect of li...  
WO/2007/104311
The present invention provides novel lactosamine derivatives and related methods suitable for the preparation, including large-scale production, of N-acetyllactosamine, lactosamine, numerous lactosamine salts and a number of lactosamine-...  
WO/2007/105094
Disclosed is a method for producing new leads for drug candidates. The method employs a combinatorial approach for identifying high affinity ligands. The target may be unknown and/or may include one or more unknown binding sites. A metho...  
WO/2007/102396
Disclosed is a method for production of a labeled sphingolipid, comprising reacting a sphingolipid or lysosphingolipid with an aliphatic carboxylic acid having a label selected from the group consisting of a substance capable of forming ...  
WO/2007/099557
A process for controlling the emission of gaseous by-products in the preparation of a Vilsmeier reagent, and its use as a chlorinating reagent in the production of high intensity sweeteners, such as trichlorogalactosucrose, from partiall...  
WO/2007/100080
[PROBLEMS] To provide a method by which the benzyl position in an -O-benzyl group formed by introducing benzyl, benzyloxymethyl, or the like as a hydroxy-protecting group is efficiently and industrially deuterized. [MEANS FOR SOLVING PRO...  
WO/2007/099999
It is intended to provide a compound represented by the following general formula (1) or its salt: (1) wherein each symbol is as defined in the description. The above-described compound or its salt can preferentially induce the productio...  
WO/2007/099981
To provide a novel and useful galactose derivative, which is a component of a drug carrier enabling the improvement in the liver-targeting properties and the efficient achievement of drug efficacy, a drug carrier containing this derivati...  
WO/2007/099557
A process for controlling the emission of gaseous by-products in the preparation of a Vilsmeier reagent, and its use as a chlorinating reagent in the production of high intensity sweeteners, such as trichlorogalactosucrose, from partiall...  
WO/2007/098124
This invention describes processes for the convergent synthesis of calicheamicin derivatives of Formula (I)1 and similar analogs using bifunctional and trifunctional linker intermediates.  
WO/2007/096367
A process of forming a polyol includes the steps of providing an alkylene oxide, providing an initiator composition having an average functionality of at least four, and providing an alkaline earth metal hydroxide and an amine. The proce...  
WO/2007/096367
A process of forming a polyol includes the steps of providing an alkylene oxide, providing an initiator composition having an average functionality of at least four, and providing an alkaline earth metal hydroxide and an amine. The proce...  

Matches 551 - 600 out of 6,434