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Matches 551 - 600 out of 6,401

Document Document Title
WO/2007/139556
A method of treating cancer in a subject comprising administering to the subject in need of the treatment a therapeutically effective amount of an alkylating agent such as temozolomide and a substituted anthracycline compound.  
WO/2007/131444
The present invention provides two kinds of new crystallographic form of the compound 3,4',5-trihydroxyl-stilbene-3-beta-D-glucoside, their manufature and medication combination comprising II-crystallographic form or III- crystallographi...  
WO/2007/128480
The present invention relates to thioglycosides and stereoisomeric forms, solvates, hydrates and/or pharmaceutically acceptable salts of these compounds, as well as pharmaceutical compositions containing at least one of these thioglycosi...  
WO/2007/128480
The present invention relates to thioglycosides and stereoisomeric forms, solvates, hydrates and/or pharmaceutically acceptable salts of these compounds, as well as pharmaceutical compositions containing at least one of these thioglycosi...  
WO/2007/126117
The object is to provide a novel phenyl 5-thioglucoside compound which can control IGT (impaired glucose tolerance) by inhibiting the SGLT1 activity and inhibiting the absorption of glucose through a digestive tract. Provided is a phenyl...  
WO/2007/125176
The invention relates to an improved process for the production of a sugar alcohol from the corresponding sugar through catalytic hydrogenation. Especially, the invention relates to a process for reducing the interference of sugar-derive...  
WO/2007/123403
The present invention discloses a therapeutic target for the treatment of cyst ic fibrosis. It was found that inhibition of non-lysosomal glucosylceramidase (GBA2) sufficiently restores chloride current in cells from CF patients carrying...  
WO/2007/124102
The present invention concerns the isolation of phlorizin from plants of the genus Lithocarpus, phlorizin-containing compositions and their uses.  
WO/2007/124102
The present invention concerns the isolation of phlorizin from plants of the genus Lithocarpus, phlorizin-containing compositions and their uses.  
WO/2007/118947
Compounds derived from α-C-phenyl-N-tert-butylnitrone, a process for the preparation thereof and use thereof for the preparation of medicaments for use in preventing or treating oxidative stress-related diseases.  
WO/2007/117500
Processes for the synthesis of lipochitooligosaccharides were developed. A fully acylated oligoglucosamine precursor is prepared and reacted with a glucosamine monomer that has an amine protecting phthaloyl group. With removal of the pht...  
WO/2007/118143
A method for producing isolated limonoid glucoside compounds is disclosed which includes extracting a quantity of defatted citrus seed powder with a solvent, filtering the resulting extract to yield a particle free extract and concentrat...  
WO/2007/117500
Processes for the synthesis of lipochitooligosaccharides were developed. A fully acylated oligoglucosamine precursor is prepared and reacted with a glucosamine monomer that has an amine protecting phthaloyl group. With removal of the pht...  
WO/2007/112567
Archaeal lipid adjuvants are synthesized by chemically coupling various carbohydrates or anionic polar groups to the free hydroxyl(s) of archaeal lipid cores. Chemically stable lipid cores such as saturated archaeol and caldarchaeol are ...  
WO/2007/111214
Disclosed is a novel trehalose compound having a high affinity to an adenosine A3 receptor. The trehalose compound is represented by the general formula (1): (1) wherein X and X’ independently represent a hydrogen atom or the like; Y a...  
WO/2007/107285
The present invention relates to compounds of general formula (I), wherein R1-R4 are as defined in the description, to processes for their preparation and to their use as medicaments. The compounds of formula (I) inhibit the effect of li...  
WO/2007/104311
The present invention provides novel lactosamine derivatives and related methods suitable for the preparation, including large-scale production, of N-acetyllactosamine, lactosamine, numerous lactosamine salts and a number of lactosamine-...  
WO/2007/105094
Disclosed is a method for producing new leads for drug candidates. The method employs a combinatorial approach for identifying high affinity ligands. The target may be unknown and/or may include one or more unknown binding sites. A metho...  
WO/2007/102396
Disclosed is a method for production of a labeled sphingolipid, comprising reacting a sphingolipid or lysosphingolipid with an aliphatic carboxylic acid having a label selected from the group consisting of a substance capable of forming ...  
WO/2007/099557
A process for controlling the emission of gaseous by-products in the preparation of a Vilsmeier reagent, and its use as a chlorinating reagent in the production of high intensity sweeteners, such as trichlorogalactosucrose, from partiall...  
WO/2007/100080
[PROBLEMS] To provide a method by which the benzyl position in an -O-benzyl group formed by introducing benzyl, benzyloxymethyl, or the like as a hydroxy-protecting group is efficiently and industrially deuterized. [MEANS FOR SOLVING PRO...  
WO/2007/099999
It is intended to provide a compound represented by the following general formula (1) or its salt: (1) wherein each symbol is as defined in the description. The above-described compound or its salt can preferentially induce the productio...  
WO/2007/099981
To provide a novel and useful galactose derivative, which is a component of a drug carrier enabling the improvement in the liver-targeting properties and the efficient achievement of drug efficacy, a drug carrier containing this derivati...  
WO/2007/099557
A process for controlling the emission of gaseous by-products in the preparation of a Vilsmeier reagent, and its use as a chlorinating reagent in the production of high intensity sweeteners, such as trichlorogalactosucrose, from partiall...  
WO/2007/098124
This invention describes processes for the convergent synthesis of calicheamicin derivatives of Formula (I)1 and similar analogs using bifunctional and trifunctional linker intermediates.  
WO/2007/096367
A process of forming a polyol includes the steps of providing an alkylene oxide, providing an initiator composition having an average functionality of at least four, and providing an alkaline earth metal hydroxide and an amine. The proce...  
WO/2007/096367
A process of forming a polyol includes the steps of providing an alkylene oxide, providing an initiator composition having an average functionality of at least four, and providing an alkaline earth metal hydroxide and an amine. The proce...  
WO/2007/096317
A process of forming a polyol includes the steps of p roviding an alkylene oxide, providing an initiator composition having an average functionality of at least four, and providing an alkaline earth metal hydroxide and an amine. The proc...  
WO/2007/098124
This invention describes processes for the convergent synthesis of calicheamicin derivatives of Formula (I)1 and similar analogs using bifunctional and trifunctional linker intermediates.  
WO/2007/097643
This invention relates to compounds that are analogues of coformycin, pharmaceutical compositions containing the compounds, and methods of using the compounds for treating protozoan parasite infections, especially malaria.  
WO/2007/091040
A process for the preparation of a thiosaccharide represented by Saccharide-S-H wherein Saccharide comprises at least 4 sugar units, comprises subjecting a corresponding compound of the formula (P)Saccharide-S-(P) wherein (P) represents ...  
WO/2007/091040
A process for the preparation of a thiosaccharide represented by Saccharide-S-H wherein Saccharide comprises at least 4 sugar units, comprises subjecting a corresponding compound of the formula (P)Saccharide-S-(P) wherein (P) represents ...  
WO/2007/091393
[PROBLEMS] To provide a compound which has a novel structure and is effective against an influenza bacterium and an erythromycin-resistant bacterium (e.g., an erythromycin-resistant pneumococcal or streptococcal bacterium), as well as a ...  
WO/2007/085962
This invention relates to compositions and methods of preparing stable adjuvant diluent stock solutions and final adjuvant solutions comprising glycolipids, weak acids, alcohols, nonionic surfactants and buffers.  
WO/2007/085962
This invention relates to compositions and methods of preparing stable adjuvant diluent stock solutions and final adjuvant solutions comprising glycolipids, weak acids, alcohols, nonionic surfactants and buffers.  
WO/2007/086884
The invention describes novel organic nitric oxide donor salts of a antimicrobial . compounds, and novel compositions and kits comprising at least one organic nitric oxide donor salt of an antimicrobial compound, and, optionally, at leas...  
WO/2007/083594
It is intended to provide a laxative with a gentle cathartic action and reduced diarrhea episodes and a food containing the same. A laxative containing genkwanin 5-O-β-primeveroside as an active ingredient. A laxative containing iriflop...  
WO/2007/084856
This invention relates to improved methods for purifying polysaccharides from cellular components, such as a cell wall. The method relates to hydrolyzing and separating the polysaccharides, thereby resulting in purified polysaccharides u...  
WO/2007/077770
The object is to provide a 4-alkylresorcinol derivative in which defects inherent to a 4-alkylresorcinol are overcome and which is excellent in solubility in water and stability, has substantially no taste and no odor, is not irritative,...  
WO/2007/076704
Aryl dihydro-naphthalene lignan derivatives of the following formula with Akt inhibiting activity, and the method of the said compounds and the pharmaceutical composition containing the compounds for treating cancer by inhibiting Akt act...  
WO/2007/075094
The present invention relates to novel derivatives of epirubicin, pharmaceutical composition comprising these derivatives, and uses of epirubicin and its derivative for treating HCV.  
WO/2007/076345
A method of preparing an anthracyclin such as epirubicin from a starting material comprising 13-dihydrodaunorubicine (13-daunorubicinol). The method comprises producing N-Trifluoroacetyl-13-daunorubicinol from 13-daunorubicinol by acylat...  
WO/2007/075876
A process is provided for the preparation of a key intermediate in the preparation of 2'-branched nucleoside compounds. The process includes contacting a protected precursor 3,4-O-isopropylidene-2-C-substituted-D-arabinono-l,5-lactone w...  
WO/2007/075092
New derivatives of 7-O-(3'amino-2',3',6'-trideoxy-α,β,L- arabinoheksopiranosyl)-adriamycinone (epirubicin) presented at Formula 1, where R1, R2, R3 and R4 are the same and indicate hydrogen atom, alkyl group, isopropyl, alkenyl or alki...  
WO/2007/076345
A method of preparing an anthracyclin such as epirubicin from a starting material comprising 13-dihydrodaunorubicine (13-daunorubicinol). The method comprises producing N-Trifluoroacetyl-13-daunorubicinol from 13-daunorubicinol by acylat...  
WO/2007/074788
[PROBLEMS] To provide a pharmaceutical composition comprising a ceramide-related substance having little adverse side effects as an active ingredient by using a raw material that is highly safe to a human body and is inexpensive. [MEANS ...  
WO/2007/070820
A method of preparing the anthracyclin carminomycin using a starting material comprising daunorubicin. The method comprises reacting daunorubicin or N-protected daunorubicin with soft Lewis acids for the demethylation of the 4-methoxy gr...  
WO/2007/068578
The current invention relates to a continuous process for preparing heat an alkali stable polyol composition. Alkali is added to the feed of the anion exchange resin and is allowing running the resin battery in full service mode.  
WO/2007/069733
[PROBLEMS] To provide a method for production of a ceramide-related substance from a biological tissue without the need of using an organic solvent such as ethanol which is absolutely necessary in a conventional extraction process and an...  
WO/2007/068171
The present invention relates to a new crystalline form of 3,4',5-trihydroxy-stilbene-3-β-D-glucoside, its preparation method and the use, as well as a pharmaceutical composition containing the same. The form I of 3,4',5-trihydroxy-stil...  

Matches 551 - 600 out of 6,401