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Matches 551 - 600 out of 13,371

Document Document Title
WO/2014/187464A1
The present application discloses a synthetic mixture of oligosaccharides for treating a microbiota of a mammal, preferably a human, to reduce or eliminate the activity and/or the proportion of a microbe in the microbiota that is associa...  
WO/2014/183630A1
The present invention provides a compound as represented by formula I, which has a structure as follows: R1 and R2 are glycosyl, R3 is H, hydroxyl or methoxyl; R4 is hydroxyl or methoxyl; and R5 is H, hydroxyl or methoxyl. The present in...  
WO/2014/186027A1
Aryl or heteroaryl 1-substituted triazoles are prepared by cyclizing aryl or heteroaryl hydrazines with urea and alkyl orthoformates.  
WO/2014/178195A1
The present invention provides an immunity inducer and an immunity inducing method using same. The immunity inducer has an immunopotentiation effect on any target oligosaccharide antigen, in particular oligosaccharide antigens included i...  
WO/2014/140626A3
The present invention relates to a process for the preparation of polysaccharides of 8 or more monosaccharide residues in length and polysaccharides accessible by these processes, the process comprising coupling a chain extending polysac...  
WO/2014/145713A3
This disclosure relates generally to aminoglycoside derivatives of Formula (I) as described herein. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating bacterial infection...  
WO/2014/106826A3
The invention relates to purified compound of Formula 1. The invention includes all isomeric forms and tautomeric forms of the compound of Formula 1 and pharmaceutically acceptable salts and derivatives thereof. The present invention fur...  
WO/2014/173957A2
A compound of formula (I) wherein R is a C9-23 polyunsaturated alkenyl group; X is SO3R3, SO2R3, PO3R3, PO2R3, COCHal3, or COOR3; R1 and R2 are each independently H, a C1-6 a iky I group optionally substituted with OH, C6-10 aryl group o...  
WO/2014/167537A1
This invention relates to a chemo-enzymatic synthesis of oligosaccharidesof formula 1 wherein R is selected from -OH, -N3 and -OR6 wherein R6 is selected from allyl optionally substituted by one or more methyl, propargyl optionally subst...  
WO/2014/166139A1
The present invention relates to a method for synthesizing dibekacin and arbekacin. The method comprises: using kanamycin B as an initial raw material, protecting five amino groups of the kanamycin B by using t-butyloxycarboryl, protecti...  
WO/2014/165107A2
The present invention relates to compounds useful for the treatment or prevention of bacteria infections. These compounds have formula (I) The invention also provides processes for making the compounds described herein. Furthermore, the ...  
WO/2014/159211A1
An alkenyl glycoside is prepared by reacting a metathesis-derived unsaturated fatty alcohol containing 10 to 30 carbon atoms with either (1 ) a reducible monosaccharide or composition hydrolyzable to a reducible monosaccharide, or (2) a ...  
WO/2014/157635A1
The purpose of the present invention is to provide a drug that demonstrates a pharmaceutical effect by having high mobility to the mid-brain and converting to bumetanide in the mid-brain, which is the primary site of epilepsy. The presen...  
WO/2014/154958A1
Process for preparing a composition (C1) represented by the formula (I): HO-CH2-(CHOH)n-CH2-O-(G)x-H, in which G represents the remainder of a reducing sugar, n is an integer equal to 2, 3 or 4 and x, which indicates the mean degree of p...  
WO/2014/148718A1
The present invention provides a spirostenol derivative, a composition for inducing a bone formation and/or promoting an osteoblast differentiation which includes the spirostenol derivative as an active ingredient, a biomaterial for indu...  
WO/2014/146875A1
The current invention is directed towards compounds of the general formula (I), wherein the integers are defined as follows: R1 is -(CH2)nCH(CH3)2, R2 is -(CH2)n+2CH(CH3)2, G1 selected from monosaccharides with 4 to 6 carbon atoms, x in ...  
WO/2014/146135A2
The present invention relates generally to steviol glycosides, as well as compositions comprising such steviol glycosides. The present invention further extends to methods of preparing and purifying such steviol glycosides and methods fo...  
WO/2014/140626A2
The present invention relates to a process for the preparation of polysaccharides of 8 or more monosaccharide residues in length and polysaccharides accessible by these processes, the process comprising coupling a chain extending polysac...  
WO/2014/133268A1
Disclosed are a method for preparing coumestrol and a method for preparing coumestrin preparation, wherein chitosan is treated for a predetermined amount of time during a bean growth period. Additionally, disclosed is the method for prep...  
WO/2014/086775A3
The present invention relates to binder compositions with improved amine components, and a method of manufacturing a collection of matter bound by said binder compositions.  
WO/2014/128660A1
The invention relates to methods for making an α-amino-aldehyde, preferably a 2-amino-2-deoxy sugar derivative, from an α-hydroxy-aldehyde, preferably an aldose. Intermediary 1-amino-1-deoxy-ketose derivatives, and their use as synthet...  
WO/2014/124245A1
The invention is directed to compositions and methods related to proteins that are physically associated with ceramide-like glycolipids for use as activators of NKT cells. The compositions and methods of the present invention are useful ...  
WO/2014/070991A3
Provided herein are E-selectin antagonist therapeutic agents and improvements thereto and compositions comprising these E-selectin antagonists. Methods are also provided for using these E-selectin antagonist therapeutic agents to treat a...  
WO/2014/100158A1
The present invention relates to compounds useful for the treatment or prevention of bacteria infections. These compounds have formula (I). The invention also provides pharmaceutically acceptable compositions containing the compounds and...  
WO/2014/100700A1
Disclosed herein are cytoprotective derivatives of avicin D of formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising these derivative compounds. Meth...  
WO/2014/096331A1
The invention relates to a method for making an N-substituted D-mannosamine derivative of the following formula 1 and its salts wherein R1 is a non-electron-withdrawing group,and wherein R2 is -OH or R2 is –NHR3 wherein R3 is a group r...  
WO/2014/096377A1
New hydroxy aliphatic substituted phenyl aminoalkyi ether compounds of formula (I), compositions thereof and their use as a medicament in the treatment of nervous system diseases and/or the treatment of developmental, behavioral and/or m...  
WO/2014/098833A1
Polymorphic and amorphous forms of Rebaudioside X and methods for preparing the same are provided herein. Also provided herein are Rebaudioside X complexes and methods for preparing the same. Sweetener compositions and sweetened composit...  
WO/2014/089226A1
With the rise in resistance to antibiotics such as methicillin, there is a need for new drugs. The invention provides small molecules that inhibit cellular drug targets such as UPPS and FPPS by interacting with binding pockets, thereby p...  
WO/2014/088432A1
The invention relates to sphingoglycolipid analogues and peptide derivatives thereof, which are useful in treating or preventing diseases or such as those relating to infection, atopic disorders, autoimmune diseases or cancer.  
WO/2014/084744A1
The invention relates to dendritic compounds, the use of these compounds as pharmaceuticals, pharmaceutical compositions containing the compounds, processes for preparing the compounds, and methods of treating diseases or conditions in w...  
WO/2014/079300A1
The present invention relates to a method for preparing highly pure doxorubicin. The method comprises the following steps: (1) chromatographing a prepurified doxorubicin solution by using macroporous resin, pre-washing the chromatographe...  
WO/2014/077960A1
The present invention provides carbohydrate-based surfactants and methods for producing the same. Methods for producing carbohydrate -based surfactants include using a glycosylation promoter to link a carbohydrate or its derivative to a ...  
WO/2014/076425A1
The subject matter of the invention is a method for obtaining polyphenols from a vegetable raw material containing same, characterised in that it comprises at least the following steps: - optionally drying the raw material containing the...  
WO/2014/070988A1
Compounds and methods are provided for enhancing the oral availability of glycomimetics. More specifically, in an embodiment, a glycomimetic is modified to decrease the polar surface area of the glycomimetic in order to increase absorpti...  
WO/2014/070991A2
Provided herein are E-selectin antagonist therapeutic agents and improvements thereto and compositions comprising these E-selectin antagonists. Methods are also provided for using these E-selectin antagonist therapeutic agents to treat a...  
WO/2014/067995A1
The present invention relates to a method of preparation of α-galactosyl ceramides compounds of formula (I) comprising a step a) of glycosylation of a compound of formula (II) with a compound of formula (III).  
WO/2014/070709A1
Adjuvants comprising chitosan cross-linked with, an aldehyde or mannosylated chitosan are provided herein. Methods of making the adjuvants and methods of combining or linking the adjuvants with antigens are also provided. The adjuvant-an...  
WO/2014/066274A1
The present invention related to low-chloride alkylated cyclodextrin compositions, along with processes for preparing and using the same. The processes of the present invention provide alkylated cyclodextrins with low levels of drug-degr...  
WO/2014/064161A1
The present invention concerns a process for the purification of tritium markedparomomycin ([3H]paromomycin), highly pure tritiated paromomycin obtained by said process and a composition comprising said paromomycin. The present invention...  
WO/2014/063441A1
The present invention relates to a use of a triterpene derivative of formula (I) for producing drugs which can be used for the prevention or treatment of influenza diseases, wherein the substituents are as defined in the specification. T...  
WO/2014/059740A1
Disclosed are a compound as shown in formula (I) and pharmaceutically acceptable salts thereof. R1, R2, R3, R4, R5, W, and n are defined as in the description of the present application.  
WO/2014/060408A1
The invention relates to compounds of the general formula (I) in which R1 is a hydrogen atom, a hydroxy or methoxy group, a halogen atom, or an NO2 group; R2 is a hydrogen atom, a hydroxy or methoxy group, or an acyl or aroyl group; R3 i...  
WO/2014/056038A1
The present disclosure provides a compound of the following formula, racemates, enantiomers, prodrugs and salts thereof: Formula (I). Also provided is the use of these compounds for the treatment of ischemia and reperfusion injuries. Fur...  
WO/2014/059220A1
The invention provides, inter alia, immunoinhibitory glycosphingolipids and immunoinhibitory alpha-galactosylceramides and compositions and preparations thereof, and methods of use thereof including in the treatment of conditions charact...  
WO/2014/055474A1
The present invention relates to compounds useful for the treatment or prevention of bacteria infections. The invention also provides pharmaceutically acceptable compositions containing the compounds and methods of using the compositions...  
WO/2014/054601A1
The present invention aims at providing: a sugar derivative capable of producing a blue fluorescent color, which can be used for the imaging of a cell or an intracellular molecule; and a method for imaging a cell using the derivative. Th...  
WO/2014/053603A1
The invention relates to compounds of formula (I); wherein A and L are as defined in the description. The invention also relates to immunogens obtained from said compounds, and to antibodies raised against said immunogens. The compounds ...  
WO/2014/052457A1
Sweetener compositions comprising particular glycoside blends are described in this paper. The glycoside blends comprise any or all of rebaudioside A, rebaudioside B, and rebaudioside D together with stevioside in various proportions. Th...  
WO/2014/048439A1
The invention relates to a method for producing a glycoconjugate comprising an oligosaccharide part covalently linked to a non-sugar moiety selected from the group consisting of amino acids, peptides, proteins, lipids, longer alkyl group...  

Matches 551 - 600 out of 13,371