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Matches 601 - 650 out of 6,434

Document Document Title
WO/2007/096317
A process of forming a polyol includes the steps of p roviding an alkylene oxide, providing an initiator composition having an average functionality of at least four, and providing an alkaline earth metal hydroxide and an amine. The proc...  
WO/2007/098124
This invention describes processes for the convergent synthesis of calicheamicin derivatives of Formula (I)1 and similar analogs using bifunctional and trifunctional linker intermediates.  
WO/2007/097643
This invention relates to compounds that are analogues of coformycin, pharmaceutical compositions containing the compounds, and methods of using the compounds for treating protozoan parasite infections, especially malaria.  
WO/2007/091040
A process for the preparation of a thiosaccharide represented by Saccharide-S-H wherein Saccharide comprises at least 4 sugar units, comprises subjecting a corresponding compound of the formula (P)Saccharide-S-(P) wherein (P) represents ...  
WO/2007/091040
A process for the preparation of a thiosaccharide represented by Saccharide-S-H wherein Saccharide comprises at least 4 sugar units, comprises subjecting a corresponding compound of the formula (P)Saccharide-S-(P) wherein (P) represents ...  
WO/2007/091393
[PROBLEMS] To provide a compound which has a novel structure and is effective against an influenza bacterium and an erythromycin-resistant bacterium (e.g., an erythromycin-resistant pneumococcal or streptococcal bacterium), as well as a ...  
WO/2007/085962
This invention relates to compositions and methods of preparing stable adjuvant diluent stock solutions and final adjuvant solutions comprising glycolipids, weak acids, alcohols, nonionic surfactants and buffers.  
WO/2007/085962
This invention relates to compositions and methods of preparing stable adjuvant diluent stock solutions and final adjuvant solutions comprising glycolipids, weak acids, alcohols, nonionic surfactants and buffers.  
WO/2007/086884
The invention describes novel organic nitric oxide donor salts of a antimicrobial . compounds, and novel compositions and kits comprising at least one organic nitric oxide donor salt of an antimicrobial compound, and, optionally, at leas...  
WO/2007/083594
It is intended to provide a laxative with a gentle cathartic action and reduced diarrhea episodes and a food containing the same. A laxative containing genkwanin 5-O-β-primeveroside as an active ingredient. A laxative containing iriflop...  
WO/2007/084856
This invention relates to improved methods for purifying polysaccharides from cellular components, such as a cell wall. The method relates to hydrolyzing and separating the polysaccharides, thereby resulting in purified polysaccharides u...  
WO/2007/077770
The object is to provide a 4-alkylresorcinol derivative in which defects inherent to a 4-alkylresorcinol are overcome and which is excellent in solubility in water and stability, has substantially no taste and no odor, is not irritative,...  
WO/2007/076704
Aryl dihydro-naphthalene lignan derivatives of the following formula with Akt inhibiting activity, and the method of the said compounds and the pharmaceutical composition containing the compounds for treating cancer by inhibiting Akt act...  
WO/2007/075094
The present invention relates to novel derivatives of epirubicin, pharmaceutical composition comprising these derivatives, and uses of epirubicin and its derivative for treating HCV.  
WO/2007/076345
A method of preparing an anthracyclin such as epirubicin from a starting material comprising 13-dihydrodaunorubicine (13-daunorubicinol). The method comprises producing N-Trifluoroacetyl-13-daunorubicinol from 13-daunorubicinol by acylat...  
WO/2007/076345
A method of preparing an anthracyclin such as epirubicin from a starting material comprising 13-dihydrodaunorubicine (13-daunorubicinol). The method comprises producing N-Trifluoroacetyl-13-daunorubicinol from 13-daunorubicinol by acylat...  
WO/2007/075876
A process is provided for the preparation of a key intermediate in the preparation of 2'-branched nucleoside compounds. The process includes contacting a protected precursor 3,4-O-isopropylidene-2-C-substituted-D-arabinono-l,5-lactone w...  
WO/2007/075092
New derivatives of 7-O-(3'amino-2',3',6'-trideoxy-α,β,L- arabinoheksopiranosyl)-adriamycinone (epirubicin) presented at Formula 1, where R1, R2, R3 and R4 are the same and indicate hydrogen atom, alkyl group, isopropyl, alkenyl or alki...  
WO/2007/076345
A method of preparing an anthracyclin such as epirubicin from a starting material comprising 13-dihydrodaunorubicine (13-daunorubicinol). The method comprises producing N-Trifluoroacetyl-13-daunorubicinol from 13-daunorubicinol by acylat...  
WO/2007/074788
[PROBLEMS] To provide a pharmaceutical composition comprising a ceramide-related substance having little adverse side effects as an active ingredient by using a raw material that is highly safe to a human body and is inexpensive. [MEANS ...  
WO/2007/070820
A method of preparing the anthracyclin carminomycin using a starting material comprising daunorubicin. The method comprises reacting daunorubicin or N-protected daunorubicin with soft Lewis acids for the demethylation of the 4-methoxy gr...  
WO/2007/068578
The current invention relates to a continuous process for preparing heat an alkali stable polyol composition. Alkali is added to the feed of the anion exchange resin and is allowing running the resin battery in full service mode.  
WO/2007/068578
The current invention relates to a continuous process for preparing heat an alkali stable polyol composition. Alkali is added to the feed of the anion exchange resin and is allowing running the resin battery in full service mode.  
WO/2007/069733
[PROBLEMS] To provide a method for production of a ceramide-related substance from a biological tissue without the need of using an organic solvent such as ethanol which is absolutely necessary in a conventional extraction process and an...  
WO/2007/068171
The present invention relates to a new crystalline form of 3,4',5-trihydroxy-stilbene-3-β-D-glucoside, its preparation method and the use, as well as a pharmaceutical composition containing the same. The form I of 3,4',5-trihydroxy-stil...  
WO/2007/070820
A method of preparing the anthracyclin carminomycin using a starting material comprising daunorubicin. The method comprises reacting daunorubicin or N-protected daunorubicin with soft Lewis acids for the demethylation of the 4-methoxy gr...  
WO/2007/068745
The invention concerns novel polyunsaturated compounds of formula (I) wherein: R1 represents a R'1, -A-R'1 group, R'1 being selected among - COOH, -COOR3, -CONH2, -CONHR3, -CONR3 R4, -CHO, -CH2OH, -CH2OR5, and A represents a C2-C16 alkyl...  
WO/2007/066805
According to the invention, a compound represented by the formula (I) (wherein A represents an aryl group or a monocyclic or dicyclic heterocyclic group, R1 represents a halide, a nitro group, a substituted C1-6 alkyl group, an amino gro...  
WO/2007/064954
The present invention is directed to analogs of aminoglycoside compounds as well as their preparation and use as prophylactic or therapeutics against microbial infection.  
WO/2007/064954
The present invention is directed to analogs of aminoglycoside compounds as well as their preparation and use as prophylactic or therapeutics against microbial infection.  
WO/2007/063356
The present invention relates to monosaccharide derivatives as anti-inflammatory agents. The compounds of this invention can be useful for inhibition and prevention of inflammation and associated pathologies, including inflammatory and a...  
WO/2007/063356
The present invention relates to monosaccharide derivatives as anti-inflammatory agents. The compounds of this invention can be useful for inhibition and prevention of inflammation and associated pathologies, including inflammatory and a...  
WO/2007/061796
The present invention relates generally to pharmaceutical compositions comprising non-caloric or low-caloric high-potency sweeteners and methods for making and using them, in particular, the present invention relates to different pharmac...  
WO/2007/061796
The present invention relates generally to pharmaceutical compositions comprising non-caloric or low-caloric high-potency sweeteners and methods for making and using them, in particular, the present invention relates to different pharmac...  
WO/2007/056525
The invention relates to high affinity Siglec ligands that are useful for isolating cells that express Siglecs and for delivering agents to cells that express Siglecs. In one embodiment, the invention provides a method for treating cance...  
WO/2007/054977
The present invention relates to a compound of formula I: [(C)-(L')]n-(A)-[(L)-(B)]mwherein (A) is a thioglycosylated cysteine of formula IIa or IIb: IIa IIb; (B) is a melanogenosis-inhibiting peptide comprising peptide sequence selected...  
WO/2007/049819
Disclosed is a therapeutic agent for a disease in which an NKT cell or the stimulation of an NKT cell is involved in the aggravation of a morbid condition thereof. The therapeutic agent comprises a chemically synthesized glycolipid deriv...  
WO/2007/050668
There are disclosed compound of formula I, in which R1 represents a hydrophobic moiety adapted to occupy the C’ channel of human CDId, R2 represents a hydrophobic moiety adapted to occupy the A' channel of human CDId, such that R1 fill...  
WO/2007/048974
The invention concerns novel glycoside oligomers, monomers useful for preparing same, as well as a method for preparing such oligomers and in particular D-glucosamine and N-acétyl-D-glucosamine heterooligomers, enabling the size, the de...  
WO/2007/048974
The invention concerns novel glycoside oligomers, monomers useful for preparing same, as well as a method for preparing such oligomers and in particular D-glucosamine and N-acétyl-D-glucosamine heterooligomers, enabling the size, the de...  
WO/2007/045469
The present invention relates to new adjuvants and the uses in pharmaceutical compositions, like in vaccines. In particular, the present invention provides new compounds useful as adjuvants for prophylactic and/or therapeutic vaccination...  
WO/2007/042469
The present invention relates compounds of the formula: oligosaccharide-spacer-(GpIIb/IIIa antagonist), wherein the oligosaccharide is a negatively charged oligosaccharide residue comprising four to twenty five monosaccharide units, the ...  
WO/2007/042470
The present invention relates compounds of the formula I : oligosaccharide-spacer-GpIIb/IIIa antagonist I, wherein the oligosaccharide is a negatively charged pentasaccharide residue of the structure (I), the charge being compensated by ...  
WO/2007/042469
The present invention relates compounds of the formula: oligosaccharide-spacer-(GpIIb/IIIa antagonist), wherein the oligosaccharide is a negatively charged oligosaccharide residue comprising four to twenty five monosaccharide units, the ...  
WO/2007/041514
A process is described for selectively extracting cocoa procyanidins from an aqueous mixture of cocoa polyphenols by using a particular sequence of solvents to extract selected procyanidin monomers and/or oligomers. The solvents are n-bu...  
WO/2007/038829
The invention provides a method of identifying biologically active compounds comprising: (a) designing a first library of compounds of formula (1) to scan molecular diversity wherein each compound of the library has at least two pharmaco...  
WO/2007/033292
Compositions that include combinations of agents that inhibit carbohydrate degradation, decrease formation or severity of intestinal gas, and/or modulate insulin signalling or blood glucose levels are described. Methods of administering ...  
WO/2007/028812
The invention relates to the CGRP antagonists of general formula (I) in which R1, R2 and R3 have the definitions given in claim 1, the tautomers, isomers, diastereomers, enantiomers, anomers, hydrates, mixtures, salts, and the hydrates o...  
WO/2007/028812
The invention relates to the CGRP antagonists of general formula (I) in which R1, R2 and R3 have the definitions given in claim 1, the tautomers, isomers, diastereomers, enantiomers, anomers, hydrates, mixtures, salts, and the hydrates o...  
WO/2007/026675
Discloses is a process for producing α-D-glucopyranose, 3-O-decyl-2-deoxy-6-O-[2-deoxy-3-O-[(3R)-3-methoxydecyl]-6-O -methyl-2-[(11Z)-1-oxo-11-octadecenyl]amino]-4-O-phosphono- -D-glucopyranosyl]-2-[(1,3-dioxotetradecyl)amino]- or 1-(...  

Matches 601 - 650 out of 6,434