| Document |
Document Title |
|
WO/2005/072765 |
A method to synthesize benzyl group protected alpha-pentagalloylglucose (&agr -PGG) and related compounds. The method comprises the steps of: suspending a highly reactive acylation agent and an acylating catalyst in a donor solvent; addi...
|
|
WO/2005/070945 |
A compound represented by, e.g., the general formula (I) or a pharmacologically acceptable salt or solvate thereof. They have excellent antibacterial activity against bacteria causative of severe infectious diseases such as pneumonia and...
|
|
WO/2005/066193 |
A compound having the excellent function of inhibiting macrophage activity and represented by the following general formula: (I) [wherein Q is oxygen, C1-3 alkylene, -O-Alk-, or -O-Alk-O- (wherein Alk is C1-3 alkylene); R1 is optionally ...
|
|
WO/2005/063785 |
The invention relates to glucopyranosyloxy-substituted aromates of general formula (I), wherein R1 to R6 and R7a, R7b, R7c are defined according to patent claim 1. The invention also relates to the tautomers, stereoisomers, mixtures and ...
|
|
WO/2005/063848 |
A modified polyol having alkoxylation and amine capping units, uses of the modified polyol having alkoxylation and amine capping units, and leaning compositions having the modified polyol having alkoxylation and amine capping units.
|
|
WO/2005/063847 |
A modified polyol compound having alkoxylation and having at least one anionic capping unit, uses of the modified polyol compound having alkoxylation and having at least one anionic capping unit and cleaning compositions comprising the s...
|
|
WO/2005/063784 |
The present invention relates to synthetic compounds that are active on plants, especially as legume nodulation factors, and also as plant growth stimulators, and to methods for preparing such compounds, which are of formula (I):'Veuille...
|
|
WO/2005/063263 |
The invention relates to novel derivatives of morphine-6-glucuronide, the preparation method thereof and the uses of same in therapy, for example, as analgesics.
|
|
WO/2005/062748 |
Bicyclic carbohydrates for the treatment of infections caused by herpseviridae, and in particular cytomegalovirus. The invention consists of the novel bicyclic carbohydrates the generic structure of which is formula I: wherein R1 is eith...
|
|
WO/2005/063797 |
The present invention provides novel nonnatural C-linked carbo-β-peptides with robust secondary structures, which comprises the synthesis of a new class of β-peptides called C-linked carbo-β-peptides, most of which are favorably dispo...
|
|
WO/2005/062824 |
This invention provides cholesterol absorption inhibitors of formula (I), and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and fo...
|
|
WO/2005/061523 |
The invention relates to compounds that are designed to mimic the structure of GAGs; methods for the preparation of the compounds; compositions comprising the compounds; and use of the compounds and compositions thereof for the anti-angi...
|
|
WO/2005/060573 |
The present invention relates to methods and compositions pertaining to conjugates composed of a peptide nucleic acid (PNA) moiety and a neamine derivative moiety. Methods for using such conjugates for modulating the activity of a target...
|
|
WO/2005/056572 |
The present invention provides novel clustered multi-antigenic; constructs having the structure (I) and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, prefe...
|
|
WO/2005/054264 |
Compounds and methods are provided for modulating in vivo and in vivo processes mediated by selectin biniding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g. inhibi...
|
|
WO/2005/054264 |
Compounds and methods are provided for modulating in vivo and in vivo processes mediated by selectin biniding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g. inhibi...
|
|
WO/2005/051969 |
Various compounds obtained from plants of the Barringtonia species which are derived from Barringtoside A and Barringtoside C as precursor compounds which especially have an arabinopyranosyl substituent at the 21 position which may optio...
|
|
WO/2005/051920 |
Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhib...
|
|
WO/2005/048921 |
Novel bicyclic carbohydrate compounds are effective for the prophylaxis and treatment of diseases caused by infections of the alphaherpesvirinae HSV-1 and HSV-2.
|
|
WO/2005/049598 |
The invention relates to novel hydrosoluble yellow colouring agents of general formula (I), wherein n is equal to 0 or 1, R1 is H or an alkyl group, R2 is H, a glucose group or a xyloglucose group. A method for preparing and using the in...
|
|
WO/2005/049631 |
The present invention is directed to synthetic molecules having biological activity similar to PIM (acyl glycerol phosphatidylinositol manno-oligosaccharide) activity, for use in the treatment and prevention of inflammatory or immune cel...
|
|
WO/2005/044256 |
The instant invention provides novel cholesterol absorption inhibitors of Formula I and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholester...
|
|
WO/2005/041983 |
The invention relates to a medicament comprising at least one reducing alkyl-sugar monomer having a hydroxyl function which is substituted by an alkoxy radical at C2-C40, said medicament being preferably intended to regulate inflammatory...
|
|
WO/2005/042539 |
Tocopherol-modified therapeutic drug compounds; emulsion, microemulsion, and micelle formulations that include the compounds; methods for making the compounds and formulations; methods for administering the compounds and formulations; an...
|
|
WO/2005/042553 |
The invention relates to a method of preparing oligorhamnosides, comprising a one-pot reaction in acetonitrile without any rhamnose protection or deprotection reaction. The invention also relates to a composition comprising a mixture of ...
|
|
WO/2005/037849 |
The present invention relates to a process for preparing solidified maltitol. The solidified maltitol is prepared by turbulating a maltitol powder with gas and contacting it with a maltitol containing syrup wherein the quantity of the po...
|
|
WO/2005/037711 |
Herein are disclosed substituted fullerenes, comprising a fullerene core (Cn), wherein n is an even integer greater than or equal to 60; 3 or 5 dihydrocarbylmalonate (>C(COOR1)(COOR2)) groups bonded to the fullerene core; and 1 or 3 pola...
|
|
WO/2005/037187 |
The present invention relates to long branched poly-N-acetyllactosamines and analogous spacer modified divalent sialosides binding to the large binding site of influenza hemagglutinin. The invention further relates to the method for eval...
|
|
WO/2005/033122 |
A process for selectively and easily producing a glycerol glycoside in which the hydroxy group in the 1-position of the glycerol has been glycosylated and which is useful as a glyceroglycolipid precursor, humectant, etc. Provided are: a ...
|
|
WO/2005/033652 |
The invention relates to techniques for measuring and comparing relative molecular flux rates of different biological molecules by administering isotope-labeled water to one or more tissues or individuals and comparing the molecular flux...
|
|
WO/2005/033100 |
The present invention relates to novel hypocholesterolemic compounds of formula (I) useful in the treatment and prevention of atherosclerosis and for the reduction of cholesterol levels as well as to pharmaceutical compositions comprisin...
|
|
WO/2005/027828 |
This invention features a compound of the following formula: T-(-L-C)m, T is a transportophore, L is a bond or a linker having a molecular weight up to 240 dalton, C is a non-antibiotic therapeutic agent, and m is 1, 2, 3, 4, 5, 6, 7, or...
|
|
WO/2005/028491 |
This invention relate to a Epimeredi Glycoside A of formula 1, and the formulation containing thereof and their preparation method. The formulations are various oral formulations comprising of extracts from. the roots of Epimeredi indica...
|
|
WO/2005/025513 |
Reagents and methods useful for the synthesis of conjugates comprising guanidinylated cyclic acetals are provided. Also provided are methods for increasing the cellular uptake of various therapeutic compounds and treatment modalities usi...
|
|
WO/2005/026183 |
The present invention is related to novel ascorbic acid derivatives compound showing improved stability to oxidation and the preparation method prepared by linking fructosyl moiety to ascorbic acid using by levan fructotransferase or inu...
|
|
WO/2005/021565 |
A method of synthesizing 4-R-substituted anthracyclines and their corresponding salts from 4-demethyldaunorubicin includes the steps of treating 4-demethyldaunorubicin with a sulfonylating agent to form 4-demethyl-4-sulfonyl-R 3 -daunoru...
|
|
WO/2005/021497 |
Derivatives of 1,4-diphenylazetidin-2-ones useful for the treatment of hypercholesterolemia are disclosed. The compounds are of the general Formula (I).
|
|
WO/2005/021501 |
Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the ...
|
|
WO/2005/019236 |
Sulfenamide oxide compounds of general formula (I) are disclosed wherein A, R1, R2, X1, X1’, X2, X2’, X3, X3’, X4, X4’, X5 and X5’ define a variety of variables and wherein q is 0 or 1 and p is 1 or 2. The compounds disclosed i...
|
|
WO/2005/019237 |
Sulfenamide compounds of general formula (I) are disclosed wherein A, R1, R2, X1, X1’, X2, X2’, X3, X3’, X4, X4’, X5 and X5’ define a variety of variables and q is 0 or 1. The compounds of the examples are galactofuranosyl and ...
|
|
WO/2005/019238 |
Compounds represented by the general formula (1) or pharmaceutically acceptable salts thereof, effective in the prevention and/or treatment of infections with microbes: (1) (a) wherein R1 is hydrogen or straight-chain C1-6 alkylcarbonyl;...
|
|
WO/2005/017180 |
The use of sugar-containing hydrogels as very highly porous, aqueous support material for the immobilization of oligonucleotides, peptides, proteins, antigens, antibodies, polysaccharides, and other biomolecules for sensor applications. ...
|
|
WO/2005/014608 |
The current invention relates to a process for preparing maltitol enriched products and said process is chromatographically fractionating a maltose syrup followed by hydrogenating it into a liquid maltitol enriched product and optionally...
|
|
WO/2005/015155 |
The invention relates to techniques for measuring and comparing relative molecular flux rates of different biological molecules by administering isotope-labeled water to one or more tissues or individuals and comparing the molecular flux...
|
|
WO/2005/012321 |
A compound of the formula (I): wherein Ring A and Ring B are (1) Ring A is an optionally substituted unsaturated monocyclic heterocyclic ring, and Ring B is an optionally substituted unsaturated monocyclic heterocyclic ring, an optionall...
|
|
WO/2005/012320 |
Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including gram positive organisms, and may be...
|
|
WO/2005/012242 |
This invention relates to to substituted benzimidazole-O-glucosides, benztriazole-O-glucosides, and benzimidazolone-O-glucosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of d...
|
|
WO/2005/009597 |
The invention relates to techniques for measuring and comparing relative molecular flux rates of different biological molecules by administering isotope-labeled water to one or more tissues or individuals and comparing the molecular flux...
|
|
WO/2005/007172 |
A medical preparation which can maximize the effect of a cholestanol glycoside useful as an antitumor agent. It is a liposome which comprises: a hydrophobic-compound glycoside having an antitumor activity, having GlcNAc-Gal-, GlcNAc-Gal-...
|
|
WO/2005/007667 |
[PROBLEMS] A novel curcuminoid glycoside; a pigment composition containing the glycoside; a medicinal composition for allergy treatments which contains the curcuminoid glycoside or the like; and an efficient process for producing various...
|
