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Patent Searching and Data


Matches 1,001 - 1,050 out of 13,374

Document Document Title
WO/2009/124468A1
Anthracycline antibiotic derivatives with anticancer activity, i.e. the compounds of formula (I). The present anthracycline antibiotic derivatives has the same activity as or higher activity than that of the known medicaments such as dox...  
WO/2009/121939A2
This invention relates to a compound of generic formula (I): (I) as well as a pharmaceutically acceptable salt thereof, a tautomer, optical isomer or a mixture of optical isomers in any proportion, in particular a mixture of enantiomers,...  
WO/2009/119692A1
Disclosed are: a novel glycolipid effective for the treatment of caner or the like; a novel intermediate for the synthesis of the novel glycolipid; a pharmaceutical agent comprising the novel glycolipid; and others. Specifically disclose...  
WO/2009/117196A1
Methods for utilizing the anticancer properties of terpenoid saponin compounds so as to modulate adhesion proteins, inhibit angiogenesis in tumors, modulate gene expression, modulate angiopoietin, enhance an immune response, provide adju...  
WO/2008/059035A3
The present invention relates to a novel process for the chemical synthesis of β-(1->6)-linked glucosamine disaccharides of the fomula (1) and (intermediate) compounds relating to the process. According to further aspects the invention ...  
WO/2008/134828A3
The present invention provides isolated or essentially pure diterpenoic tetrahydropyran, such as steviol-19-glucuronide, steviol, stevioside and rebaudioside processes for obtaining the same and methods for obtaining stable pharmaceutica...  
WO/2008/151615A3
The invention relates to a method for producing biosurfactants, according to which micro-organisms producing biosurfactants are moved in a nutrient substrate. According to the invention, the nutrient substrate is used in excess and a mec...  
WO/2009/107853A2
An agent for preventing or ameliorating skin aging, which exhibits a more excellent effect on the suppression of formation, or the amelioration, of wrinkles on the skin or sagging skin. An agent for preventing or ameliorating skin aging,...  
WO/2009/108680A2
Exemplary embodiments of this invention encompass a method for degrading rebaudioside A and the rebaudioside A derivative products derived therefrom. In particular, this invention relates to a method for degrading rebaudioside A composit...  
WO/2009/102736A1
The invention disclosed in this document is related to the field of pesticides and their use in controlling pests. A compound having the following structure is disclosed.  
WO/2008/092690A8
The present invention relates to paromamine-based compounds according to formula (I) having selective antimicrobial activity directed at ribosomal 16S RNA. Furthermore, the invention is directed to the use of said compounds for preparing...  
WO/2009/101213A1
The present invention relates to an enzyme called chitinosanase which is obtained from the fungus Alternaria alternate, said enzyme breaking down chitosane and specifically cleaving the glycosidic GIcNAc-GIcN bond in chitosane, DNA seque...  
WO/2009/098400A1
The invention relates to a chemical compound of the disaccharide type of the following general formula (A): where, Z = O or S; X1 = azido or NHCOR3 where R3 = 1 -5 c alkyl or aryl, X2 = benzyl, H or sulfonate, X3 = -CH2φ, -CHφ forming ...  
WO/2009/096503A1
Disclosed is a compound having a novel structure, few adverse side effects and an excellent inhibitory activity on human SGLT1 and/or SGLT2, or a hydrate of the compound. Also disclosed is a pharmaceutical composition for treating and/or...  
WO/2009/095588A2
The invention relates to compounds of the formula (I) in which: R1 = OH or NH2; OR2, OR3, OR4 and OR5 form alcohol, ether, ester, carbonate, carbamate, sulphonate or sulphamate functions; and if R5 = H, if R2 =R3=R4, then R2, R3 and R4 ...  
WO/2009/097596A1
The present disclosure provides compositions and methods for the treatment and elimination of chronic intracellular infections in cells or organisms. The compositions may include one or more acidic substances and one or more antimicrobia...  
WO/2009/093604A1
This object aims to provide an organic nanotube manufacturing method and an organic nanotube manufacturing device that pressurize an organic nanotube material dispersion solution comprised of an organic nanotube material and an organic s...  
WO/2009/059945A3
1,2-Dideoxy-1,2-diamino oligosaccharides and polysaccharides as shown in General Formula (1) and derivatives thereof are described, and methods suitable for their preparation in free-base, salt or metal-complexed form. In addition, new u...  
WO/2009/086720A1
2,3,4,6-tetra-O-acetyl-D-glucopyranosyl-[N,N'-di-(2-chloroet hyl)]-phosphoric acid diamide I, its α-configuration II and its β-configuration III. These compounds show inhibitory action on transplantation tumors in mouse from the pharma...  
WO/2009/088618A1
A method for the aralkylation of anthracyclins by utilizing an aralkylating agent R3-CH2X (for example, BnBr) in accordance with the reaction pathway describe by the scheme shown in Fig. 1. The present invention recognizes that 4-R1, 3'-...  
WO/2009/087677A1
The present invention relates to an improved process for the preparation of 2, 3, 6, 3', 4'- Penta-O-acetylsucrose 6-PAS), formula (V) and sucralose, formula (I).  
WO/2009/080215A1
Suggested are alkylene oxide adducts of oligosaccharides, obtainable in that an aqueous solution of at least one water-soluble oligosaccharide is subjected to alkoxylation within a temperature range of 90 to 160 °C.  
WO/2009/047792A3
The invention provides carbohydrate based compounds of formula (I), methods of preparation, and compositions useful for modulating signaling through Toll -like receptors. The methods involve contacting a TLR -express ing cell with a carb...  
WO/2009/081211A2
A process of obtaining a saponin-rich component from a plant of the Araliaceae family, the process comprising the steps of: (a) treating a portion of the plant with an extraction solvent in which saponin-containing compounds are soluble;...  
WO/2009/078462A1
Disclosed is a sugar chain primer represented by the following general formula (I). Lac-O-Ck:m(n) (I) (In the formula (I), Ck represents an alkenyl chain; m represents the total number of double bonds; and n represents the positions of t...  
WO/2009/075186A1
Disclosed is a method for producing a 4-deoxy-4-fluoro-D-glucose derivative, wherein a D-galactose derivative is reacted with sulfuryl fluoride (SO2F2), trifluoromethanesulfonyl fluoride (CF3SO2F) or perfluorobutanesulfonyl fluoride (C4F...  
WO/2009/067846A1
The invention discloses a purifying method of monoglycoside acid which comprises selective oxidizing primary hydroxy group of the monoglycoside, exchanging the reacted composite liquid through an activated strong acid cation exchange res...  
WO/2009/069800A1
Disclosed are a novel aminoglycoside antibiotic, a production method thereof, and a pharmaceutical use thereof. Specifically disclosed are a compound represented by the formula (I) below, a production method thereof, and a use thereof as...  
WO/2008/047249A9
The invention relates to α -galactoceramide analogs, their methods of manufacture, intermediate compounds useful in these methods. It also relates to pharmaceutical compositions containing the α-galactoceramide analogs. The methods of ...  
WO/2009/069668A1
Disclosed is a means which is effective for the treatment of melanoma. Specifically disclosed is an agent for increasing the expression of a malignant melanoma antigen, which comprises a compound selected from the group consisting of met...  
WO/2009/067692A1
Compounds of structure (I): having antibacterial activity are disclosed, including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R8 and R9 are as defined herein. Methods associated with prepar...  
WO/2009/066117A1
The invention relates to the use of ethylenediamine tetraacetic acid (EDTA) and its derivatives, i.e. its salts and complexes for prevention and treatment of bacterial intestinal diseases of pigs and for increasing the effects of antibio...  
WO/2009/060086A2
The present invention relates to compounds consisting of glycolipids covalently bound to an antigen or a drug via a linker. The said compounds are able to induce a stronger immune response than a composition comprising separated glycolip...  
WO/2009/059945A2
1,2-Dideoxy-1,2-diamino oligosaccharides and polysaccharides as shown in General Formula (1) and derivatives thereof are described, and methods suitable for their preparation in free-base, salt or metal-complexed form. In addition, new u...  
WO/2007/054977A3
The present invention relates to a compound of formula I: [(C)-(L')]n-(A)-[(L)-(B)]mwherein (A) is a thioglycosylated cysteine of formula IIa or IIb: IIa IIb; (B) is a melanogenosis-inhibiting peptide comprising peptide sequence selected...  
WO/2009/038978A3
Steviol glycoside isomers are provided having the formula (II): wherein R1may be hydrogen, 1-β-D-glucopyranosyl, or 2-(1-β-D-glucopyranosyl)-1-β-D- glucopyranosyl, and R2 may be hydrogen, 1-β-D-glucopyranosyl, 2-(1-β-D-glucopyranosy...  
WO/2009/055677A1
Synthetically-derived S,S-heterodisubstituted disulfides that exhibit potent in vitro antibacterial activity against a variety of bacteria, including Staphylococcus aureus, methicillin-resistant Staphylococcus aureus and Francisella tula...  
WO/2009/049428A1
Particular naturally occurring glycosylated acyl-flavonols, e.g. montbretm A (of the formula below wherein R1, R2, R3, R5, R5', and R7 is OH each, X is β-D-glucopyranosyl), are now shown to be effective mammalian α-amylase inhibitors S...  
WO/2009/049370A1
The invention relates to novel compounds that have utility as inhibitors of heparan sulfate-binding proteins; compositions comprising the compounds, and use of the compounds and compositions thereof for the antiangiogenic, antimetastatic...  
WO/2009/052088A2
Fire extinguishing compositions and methods of extinguishing a fire comprising compounds of formula (I) where Rf is a fluorocarbon group. The compounds and compositions described herein are useful as intermediates in the preparation of o...  
WO/2009/048343A1
The invention relates to methods for effecting qualitative and quantitative changes in the functional moieties expressed at the surface of cells and multi-cellular structures, and functional lipid constructs for use in such methods. In p...  
WO/2006/041902A3
Compositions and methods for using nordihydroguaiaretic acid (NDGA) derivatives for preventing the expression of MDR-1 gene and the synthesis of PgP protein or reversing multiple drug resistance in cells, and for using NDGA derivatives i...  
WO/2009/047792A2
The invention provides carbohydrate based compounds of formula (I), methods of preparation, and compositions useful for modulating signaling through Toll -like receptors. The methods involve contacting a TLR -express ing cell with a carb...  
WO/2008/142155A3
The present invention concerns a method for preparing C-6 phosphorylated D- aldohexoses and C-6 phosphorylated D-aldohexose derivatives, new C-6 phosphorylated D-aldohexoses derivatives and uses thereof. The method comprises incubating p...  
WO/2009/044886A1
The invention aims to provide a process for producing 1,2,3-tri-O-acetyl-5-deoxyribofuranose by an industrially suitable means. The invention provides a process for the production of 1,2,3-tri-O-acetyl-5-deoxyribofuranse which comprises ...  
WO/2007/118143A3
A method for producing isolated limonoid glucoside compounds is disclosed which includes extracting a quantity of defatted citrus seed powder with a solvent, filtering the resulting extract to yield a particle free extract and concentrat...  
WO/2005/025513A3
Reagents and methods useful for the synthesis of conjugates comprising guanidinylated cyclic acetals are provided. Also provided are methods for increasing the cellular uptake of various therapeutic compounds and treatment modalities usi...  
WO/2009/038978A2
Steviol glycoside isomers are provided having the formula (II): wherein R1may be hydrogen, 1-β-D-glucopyranosyl, or 2-(1-β-D-glucopyranosyl)-1-β-D- glucopyranosyl, and R2 may be hydrogen, 1-β-D-glucopyranosyl, 2-(1-β-D-glucopyranosy...  
WO/2009/036754A1
The invention relates to a composition having the general structure (formula), wherein R1 is a hydrophobic group, R2 is hydrogen (H), a cation or an alkyl ester, R3 is hydrogen (H) or a group that can be converted into the hydroxy group ...  
WO/2009/035107A1
Disclosed is a transformant produced by introducing a keto reductase gene involved in the biosynthesis of L-epivancosamine into a ray fungus originally capable of producing daunorubicin. Also disclosed is a method for efficiently produci...  

Matches 1,001 - 1,050 out of 13,374