Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 251 - 300 out of 13,186

Document Document Title
WO/2016/086097A8
A novel diterpene glycoside and methods for preparing and purifying the same are provided herein. In addition, compositions comprising the novel diterpene glycoside, as well as methods of using the diterpene glycoside are provided.  
WO/2017/093276A1
The present invention relates to L-arabino-oligosaccharides, in particular synthetically produced L-arabino-oligosaccharides and their uses for the prophylaxis of allergic reactions in mammals.  
WO/2017/095237A1
The present invention provides organic compounds which are capable of releasing carbon monoxide under physiological conditions or pH trigger, and to the use of such compounds for conditioning a cell, tissue or organ, for example, to prot...  
WO/2017/095904A1
Compounds, compositions, and methods for modulating in vitro and in vivo processes mediated by selectin binding. For example, heterobifunctional compounds that inhibit both E-selectins and P-selectins are described, wherein the selectin ...  
WO/2017/088058A1
The present disclosure relates to peptide compounds and conjugate compounds, processes, methods and uses thereof for treating cancer and increasing cellular internalization of said peptide compounds. The peptide compounds are selected fr...  
WO/2017/091544A1
The invention provides compounds of formula (I) which are prodrugs of a JAK inhibitor agent for the targeted delivery of the JAK inhibitor to the gastrointestinal tract of a mammal. The invention also provides pharmaceutical compositions...  
WO/2017/083967A1
The present invention provides purified compounds extracted from seaweeds having the formula (I): wherein R1 and R2 is each independently H or a fatty acid and their use for inhibiting the growth of cancer cells.  
WO/2017/084987A1
The invention comprises Gal NAc phosphoramidite derivatives of the formula (I), wherein R1 is a hydroxy protecting group, n is an integer from 0 to 10 and m is an integer from 0 to 20 and its corresponding enantiomers and/ or optical iso...  
WO/2017/075994A1
Provided are a separation and purification method for epirubicin or hydrochloride thereof. The method comprises: 1) taking epirubicin or a hydrochloride crude product thereof, and sampling macroporous absorption resin; and 2) carrying ou...  
WO/2017/079582A1
The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and ...  
WO/2017/078609A1
The present invention relates to a metal-organic framework with encapsulated target-molecule, a process for the preparation of a metal-organic framework with encapsulated target-molecule, as well as the metal-organic framework with encap...  
WO/2017/059318A3
The present disclosure relates to scaphopetalone analogs, methods of making the analogs, and their medicinal uses.  
WO/2017/078097A1
Provided is a method for stably producing (2S)-2-hydroxydibekacin, said method being characterized by the use of 2-hydroxykanamycin C or 2-hydroxykanamycin B as a starting material or synthetic intermediate.  
WO/2017/078098A1
Provided is a method for stably producing (2S)-2-hydroxydibekacin, said method being characterized by the use of 2-hydroxykanamycin C or 2-hydroxykanamycin B as a starting material or synthetic intermediate.  
WO/2017/078096A1
Provided is a method for efficiently producing a compound represented by formula II, namely (2S)-2-hydroxyarbekacin or a salt thereof from (2S)-2-hydroxydibekacin represented by formula I or a salt thereof, which is characterized by usin...  
WO/2017/071152A1
Provided are a phosphoryl mannose pentasaccharide as shown in formula (I) and derivatives of the phosphoryl mannose pentasaccharide as shown in formulas (II)-(XI), and a preparation method thereof. In the preparation method of this inven...  
WO/2016/054281A3
A method for the purification of idraparinux sodium includes: passing a solution including a crude idraparinux sodium through a column including a sodium ion exchange resin to obtain a first mixture; passing a solution including the firs...  
WO/2016/198170A8
The present invention relates to well-defined synthetic saccharides of general formula (I) that are related to the repeating unit of Streptococcus pneumoniae serotype 5 capsular polysaccharide and conjugates thereof. The conjugates and p...  
WO/2016/115048A8
Provided are organic solvent free methods for obtaining compositions comprising one or more rhamnolipids as well as compositions obtainable from said methods.  
WO/2017/063617A1
The present invention relates to a preparation method of the intermediates of structures la (for the synthesis of canagliflozin) and 1b (for the synthesis of dapagliflozin), where in structure la X is methyl and Ar represents 2-(5-(4-flu...  
WO/2017/062800A1
Disclosed are compounds for the selective labeling of cell-surface sugars in cancer cells. The compounds are activatable by triggers specific to cancer cells, and, when metabolized, label a cancer cell surface sugar with an azide chemica...  
WO/2017/058474A1
Prepare a branched alcohol-based sugar surfactant by: (a) providing an ether alcohol and a fully acetylated sugar where the ether alcohol has the structure of Structure (I); (b) coupling the ether alcohol with the acetylated sugar in the...  
WO/2017/059318A2
The present disclosure relates to scaphopetalone analogs, methods of making the analogs, and their medicinal uses.  
WO/2017/051875A1
Provided is a compound represented by formula (I) or a salt thereof (in formula (I): R1 and R2 each represent hydrogen, a C1-5 straight-chain or branched alkyl group, a C1-5 straight-chain or branched alkoxy group, or a C1-5 straight-cha...  
WO/2017/049386A1
This invention discloses the use of aminoglycoside antibiotics such as gentamicin Bl to suppress premature termination codons during translation and promote the full length read-through of transcripts such as p53 that incorporate nonsens...  
WO/2017/046172A1
The invention relates to carbohydrate ligands and moieties, respectively, mimicking glycoepitopes comprised by glycosphingolipids of the nervous system, particularly glycoepitopes comprised by glycosphingolipids of the cerebroside, the g...  
WO/2017/046535A1
The subject matter of the present invention is a compound characterized in that it has the general formula (I): in which P1, X, n, A, L and L1 are as defined in Claim 1. The present invention also relates to a process for preparing said ...  
WO/2017/043703A1
The present invention relates to a mannitol-based amphipathic compound, a method for preparing the same, a method of extraction, solubilization, stabilization or crystallization of a membrane protein using the same, and a method for anal...  
WO/2017/037719A1
Novel aminoglycosides, represented by Formulae la and lb, as defined in the instant specification, designed to exhibit stop codon mutation readthrough activity, are provided. Also provided are pharmaceutical compositions containing the s...  
WO/2017/037718A1
Novel pseudo-trisaccharide aminoglycosides, represented by Formula I, as defined in the instant specification, designed to exhibit stop codon mutation readthrough activity, are provided. Also provided are pharmaceutical compositions cont...  
WO/2017/039107A1
The present invention relates to a xylene-based amphipathic compound, a method for preparing same, and a method for extracting, solubilizing, stabilizing, or crystallizing membrane proteins by using said compound. By using the xylene-bas...  
WO/2017/037717A1
Novel pseudo-disaccharide and pseudo-trisaccharide aminoglycosides, represented by Formulae I or Ia, as defined in the instant specification, designed to exhibit stop codon mutation readthrough activity, are provided. Also provided are p...  
WO/2017/027968A1
Adjuvants which rescue antibiotics against multidrug-resistant (MDR) organisms are a promising combination strategy to overcome bacterial resistance. While the combination of β-lactam β-lactamase inhibitor antibiotic has been successfu...  
WO/2017/031189A1
The invention provides compositions and methods for the production of TDP-deoxysugars.  
WO/2017/021385A1
The invention comprises a new process for the preparation of GalNAc derivatives of the formula I wherein n is an integer between 0 and 10 and its salts, corresponding enantiomers and/ or optical isomers thereof. The GalNAc acid derivativ...  
WO/2017/017509A1
The present invention relates to novel oligomers of Neisseria meningitidis serogroup Y capsular polysaccharide repeating unit (Men-Y oligomers) and process for synthesizing novel Men- Y oligomers. In particular, the present invention rel...  
WO/2017/019599A1
A process for the extraction and concentration of saponins from agricultural feedstocks. An agricultural feedstock can undergo a first preparation step intended to increase surface area of the feedstock for increased efficiency in extrac...  
WO/2017/018528A1
Disclosed are: a compound represented by general formula (I), or a pharmaceutically acceptable salt of the compound, or a solvate of the compound or the pharmaceutically acceptable salt; a pharmaceutical composition containing the compou...  
WO/2017/012289A1
Disclosed are compounds which can act as a positive allosteric modulator for erythropoietin and erythropoietin receptor and have the activity in promoting erythropoiesis. Also disclosed are pharmaceutical compositions comprising said com...  
WO/2017/012572A1
Provided are crystalline form A of rebaudioside D, and a preparation method and application therefor. In X-ray powder diffraction analysis measured using Cu-Kα rays and with 2θ being expressed in degrees, crystalline form A of rebaudio...  
WO/2017/007346A1
The present invention relates to novel derivatives of polyphenol glycoside or polyalcohols of formula (1), wherein R1, R2, R3 is selected from the group consisting of H, OH, C(O)R4, C(0) OR4, 0 (Gly H3)n, wherein n = 0 1, 2, 3, and R4 is...  
WO/2016/100833A3
In one aspect, the present invention provides novel derivatives of trioxacarin analogs of the formula (I) wherein the variables are as defined herein. The application also provides compositions, methods of treatment, and methods of synth...  
WO/2016/202310A1
A sulphonated pentasaccharide compound having anti-Xa factor activity, and a preparation method and use for said compound. The compound is a derivative of a pentasaccharide compound having an anticoagulation effect, and has significant a...  
WO/2016/198170A1
The present invention relates to well-defined synthetic saccharides of general formula (I) that are related to the repeating unit of Streptococcus pneumoniae serotype 5 capsular polysaccharide and conjugates thereof. The conjugates and p...  
WO/2016/196927A1
Methods of using and pharmaceutical compositions comprising (2R,3S,4R,5R,6S)-5- amino-6-(((lR,2S,3S,4R,6S)-4,6-diamino-3-(((2R,3R,4R,5R)-3,5 -dihydroxy-5-methyl-4-(methylamino)tetrahydro-2H-pyran-2-yl) oxy)-2-hydroxycyclohexyl)oxy)-2- (h...  
WO/2016/189179A1
The invention relates to a compound of general formula (I), and to the use thereof in medicine, or for the production of a medicine for the treatment of different diseases, preferably a cancer such as melanoma, lung carcinoma or breast c...  
WO/2016/188381A1
The present invention relates to the technical field of medical compounds, and relates to an oxidized β-1,4-oligoglucuronic acid, and a preparation method therefor and uses thereof. In the present invention, by using abundant cellulose ...  
WO/2016/190383A1
A compound represented by structural formula (A) or (B); a method for producing the compound; a microorganism having an ability of producing the compound represented by the formula (A) or (B); and a compound-containing composition and an...  
WO/2016/181013A1
The invention relates to the use of oligosaccharides as stimulators of plant growth in already germinated plants and to a method for obtaining said oligosaccharides. The invention particularly relates to the use of oligosaccharides compo...  
WO/2016/180818A1
The present invention relates to glycosylating polyphenols via biocatalysis. More specifically the present invention discloses particular mutants of the thermostable sucrose phosphorylase derived from the microorganism Thermoanaerobacter...  

Matches 251 - 300 out of 13,186