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Matches 251 - 300 out of 13,371

Document Document Title
WO/2018/029274A1
A method for purifying rebaudioside A, which method comprises: (a) providing a solution comprising rebaudioside A; (b) concentrating the said solution; and (c) crystallizing from the solution a high purity composition comprising rebaudio...  
WO/2018/026087A2
Compounds of chemical formula 1 or pharmaceutically acceptable salts thereof according to the present invention are sugar-added enclomiphene derivatives that improve bioavailability while maintaining antagonistic activity to estrogen rec...  
WO/2018/021527A1
The present invention addresses the problem of providing a method for supplying or maintaining type-17 collagen in a living body. The problem addressed by the present invention is solved by providing a composition having as an active ing...  
WO/2018/020046A1
The present invention provides a stable synthetic saccharide of Hib polyribosylribitol- phosphate (PRP) derivative and conjugate thereof. Said saccharide, said conjugate and pharmaceutical compositions thereof are hydrolysis-resistant, l...  
WO/2018/014866A1
Disclosed are a crystal form of a dapagliflozin intermediate and a preparation method therefor, and specifically disclosed are a crystal form of the dapagliflozin intermediate (2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-2-eth ...  
WO/2018/014111A1
There is provided methods, compositions and treatment regimens for treating cancer, or for inhibiting metastasis/recurrence of cancer in a patient using 1) a primary cancer treatment such as chemotherapy, and 2) within 12 to 120 hours po...  
WO/2018/012669A1
The present invention relates to a mesitylene-cored amphiphile, a method of preparing the same and a method of extraction, solubilization, stabilization, crystallization or analysis of a membrane protein using the same. When a mesitylene...  
WO/2018/007495A1
The present invention relates to compounds of formula (I) and compositions comprising them for use in enhancing umami taste and/ or saltiness of a food product.  
WO/2018/007496A1
The present invention relates to compounds and compositions for use in enhancing flavor and/or saltiness of a food product. Particularly, the present invention relates to compounds of the general formula I) and compositions comprising them.  
WO/2018/005324A1
Disclosed herein are artificial Invaplexes comprising deacylated lipopolysaccharides and methods of making and using thereof.  
WO/2018/003652A1
A compound used in the conventional enzymatic reactions and mass spectrometry methods needs to be altered with respect to the structure thereof as a substrate compound, such as the length of an alkyl chain contained therein, depending on...  
WO/2017/218888A1
Compositions and uses for steviol glycoside compounds having four glucopyranose residues attached via the number 13 carbon (C13) of the steviol moiety and a second group of two or three glucopyranose residues attached via the number 19 c...  
WO/2017/207754A1
The invention describes novel conjugates of formula (I) of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein allowing a reversible release of the pharmaceutical agent depending on the glucose concentration.  
WO/2017/202351A1
The present invention relates to a new crystal form of a sodium-glucose co-transporter inhibitor medicine (Sotagliflozin) and a preparation method and use thereof. In addition, the present invention relates to a pharmaceutical compositio...  
WO/2017/205269A1
Compounds of Formula (I), compositions, and methods for treatment and/or prevention of at least one disease, disorder, and/or condition by inhibiting binding of an E-selectin to an E-selectin ligand are disclosed. For example, haloalkyl ...  
WO/2016/196927A8
Methods of using and pharmaceutical compositions comprising (2R,3S,4R,5R,6S)-5- amino-6-(((lR,2S,3S,4R,6S)-4,6-diamino-3-(((2R,3R,4R,5R)-3,5 -dihydroxy-5-methyl-4-(methylamino)tetrahydro-2H-pyran-2-yl) oxy)-2-hydroxycyclohexyl)oxy)-2- (h...  
WO/2017/174748A3
Surfactants based on a newly discovered class of compounds include a hydrophobic lipid oligomer covalently linked to a peptide or peptide-like chain and a carbohydrate moiety, and a serine- leucinol dipeptide linked to the lipid oligomer...  
WO/2017/199028A1
A method of preparing an active agent or a salt thereof from a prodrug first compound (1) comprising a propargyl group connected to an oxygen that is directly or indirectly connected to the active agent is provided, wherein the bond betw...  
WO/2017/196933A1
Methods of preparing freeze dried powders comprising rebaudioside M and rebaudioside D are provided herein. The freeze dried powders produced by the disclosed methods exhibit improved aqueous solubility over known forms and compositions ...  
WO/2017/185026A1
Reversibly blocked nucleoside analogues and methods of using such nucleoside analogues for sequencing of nucleic acids are provided.  
WO/2017/184884A1
Provided are methods and yeast cultures for producing polyol lipids and polyol lipid compositions.  
WO/2017/177326A1
The invention provides conjugates that comprise a targeting moiety, a nucleic acid, and optional linking groups as well as synthetic intermediates and synthetic methods useful for preparing the conjugates. The conjugates are useful to ta...  
WO/2017/178656A1
This invention generally relates to the field of phosphoramidite derivatives. In particular, the invention relates to N- Acetylgalactosamine (GalNAc) compounds, in particular phosphoramidite or phosphonoamidite molecules of formula (I) w...  
WO/2017/178497A1
The invention relates to a composition comprising one or more antimicrobial glycolipids and one or more formulation stabilizers. The invention also relates to methods of preparing the compositions and their application in water containin...  
WO/2017/179945A1
The present invention relates to an amphiphilic compound having a pentasaccharide hydrophilic group, a method for producing the same, and a method for extracting, solubilizing, stabilizing, crystallizing or analyzing a membrane protein a...  
WO/2017/174748A2
Surfactants based on a newly discovered class of compounds include a hydrophobic lipid oligomer covalently linked to a peptide or peptide-like chain and a carbohydrate moiety, and a serine- leucinol dipeptide linked to the lipid oligomer...  
WO/2017/176999A1
Disclosed are oligonucleotides that binds specifically to HIV neutralizing monoclonal antibody 2G12 with a K4 value lower than 20 nM, the oligonucleotide comprising a predicted structure, at 37°C, having exactly one stem-loop whereby th...  
WO/2017/173019A1
This invention relates to novel compositions comprising the reaction product of at least one acetoacetylated polyol and vanillin. The invention also relates to a method of making the novel compositions of the invention comprising the rea...  
WO/2017/167652A1
The invention relates to a compound characterised by a chemical dexpanthenol bound to a saccharide. The invention also relates to a corresponding compound for use in therapeutic and/or cosmetic methods.  
WO/2017/161986A1
A natural extract high-intensity sweetener steviol glycoside, specifically related to a novel steviol C-glycoside crystal, a preparation method for same, and applications thereof. The novel crystal has the advantages of high crystallinit...  
WO/2017/162825A1
The invention relates to a compound, characterized by a mono(2-hydroxyethyl) terephthalic acid (MHET) and a bis(2-hydroxyethyl) terephthalic acid which are chemically bound to a saccharide. The invention further relates to a correspondin...  
WO/2017/161987A1
The present invention relates to the naturally extracted high intensity sweetener stevioside, and specifically relates to a novel crystal form of steviolbioside, and a manufacturing method and application therefor. The novel crystal form...  
WO/2017/163808A1
The present invention addresses the problem of providing: a novel compound capable of activating a natural killer T cell, or a salt of the compound; a natural killer T cell activator comprising the compound or a salt thereof; and a pharm...  
WO/2017/161985A1
The present invention relates to a naturally-extracted high-sweetener stevioside, and in particular to a new crystal form of a rebaudioside B, and a preparation process therefor and a use thereof. The new crystal form is fully characteri...  
WO/2017/165619A1
The present invention relates to mannoside derivative compounds useful as inhibitors of FimH and methods for the treatment or prevention of urinary tract infection.  
WO/2017/157260A1
Provided are a phenylpropanoid and a preparation method and application thereof. The phenylpropanoid has a structure represented by formula (I), and a pharmaceutically acceptable salt thereof has a structure represented by formula (II) o...  
WO/2017/154938A1
[Problem] The purpose of the present invention is to provide a method for uniformly and efficiently producing a sugar having a sulfate group and/or phosphate group in the molecule or a compound containing the sugar. [Solution] The presen...  
WO/2017/156432A1
The present disclosure provides edible compositions comprising Formulas and compounds of steviol glycoside esters, or combinations thereof, which are suitable for use as sweeteners, for example, by incorporation into edible compositions....  
WO/2017/153538A1
The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.  
WO/2017/144318A1
The invention relates to derivatives of rhamnolipids of formula (I), formulations containing same, and the use thereof, in particular for scent retention on hair.  
WO/2017/144099A1
The present invention relates to a compound of formula (I) wherein the substituents are as defined in the claims. Said compound may be used as a ligand in order to purify glycosylated bio molecules. The present invention further relates ...  
WO/2017/144317A1
The invention relates to ester derivatives of rhamnolipids of formula (I) as nonionic surfactants, formulations containing same, and the use thereof.  
WO/2017/143956A1
The present invention relates to a naturally-extracted high potency sweetener rebaudioside, and particularly relates to a novel crystal form of a sodium salt of rebaudioside B and a preparation method thereof. The novel crystal form is c...  
WO/2017/134176A1
The present invention relates to a process for producing 2'-O-fucosyllactose, to the intermediates obtainable by this process and to the use of these intermediates. Production comprises the reaction of a protected fucose of general formu...  
WO/2017/132755A1
The present disclosure provides: floridoside or isethionic acid for use as an antibiotic potentiator; floridoside or isethionic acid in a combination therapy with an antibiotic compound; as well as methods of potentiating the antibiotic ...  
WO/2017/130191A1
The present invention provides dioxetane-based chemiluminescence probes, more specifically fluorophore-tethered dioxetane-based chemiluminescence probes and π* acceptor group-containing dioxetane based chemiluminescence probes, and com...  
WO/2017/131236A1
The present invention relates to the nucleic acid complex expressed by formula 1. Formula 1: (In formula 1, X is an oligonucleotide, L1 and L2 each independently represents a sugar ligand, and S1, S2 and S3 each independently represents ...  
WO/2017/129752A1
The present invention relates to neisserial LPS having a tetra-acylated lipid A moiety, wherein the tetra-acylated lipid A moiety is modified as compared to the lipid A moiety of a wild-type neisserial LPS in that it lacks one of the sec...  
WO/2017/129761A1
The present invention relates to neisserial LPS having a hexa-acylated lipid A moiety, wherein the hexa-acylated lipid A moiety is modified as compared to the lipid A moiety of a wild-type neisserial LPS in that it comprises a palmitoleo...  
WO/2017/132469A1
Various aspects of the invention relate to compositions comprising C-2a gentamicin. A composition may be substantially free from one or more of C-1 gentamicin, C-1a gentamicin, C-2 gentamicin, C-2b gentamicin, gentamicin A, gentamicin B,...  

Matches 251 - 300 out of 13,371