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WO/2008/133534 |
Carbohydrate-lipid constructs and their use in inhibiting viral infections in cells.
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WO/2008/131552 |
Clonal strains of bacteria derived from Pseudopterogorgia elisabethae are capable of making pseudopterosins in in vitro cultures without requiring the presence of other bacteria, algae, or animal cells that are normally present in P. eli...
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WO/2008/131024 |
Methods of treating glioblastoma and pancreatic cancer are provided by the administration of a therapeutically effective amount of a iodo-hexose compound to a subject in need thereof. The subject invention includes methods of treating gl...
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WO/2008/130263 |
The invention relates to molecular biology and bioorganic chemistry, in particular to hydrogels based on cross-linked polymers with oligonucleotides, proteins, nucleic acids or any other biologically significant compounds which are immob...
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WO/2008/127086 |
This invention relates to the use of palm phenolics as natural antioxidants and food preservatives. In particular, the present invention relates to antioxidant compounds derived from a plant material, wherein the said antioxidant compoun...
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WO/2008/126752 |
A skin-lightening agent containing a novel skin-lightening ingredient as an active ingredient. The active ingredient comprises equol and/or an equol glycoside formed by bonding one or more glycosyl groups to one or more of the hydroxy gr...
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WO/2008/128062 |
This invention relates to immunogenic compounds which serve as ligands for NKT (natural killer T) cells and to methods of use thereof in modulating immune responses.
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WO/2008/123070 |
Lactosylceramide can be produced by heat-treating ganglioside GD3 and/or ganglioside GM3 for at 70 to 100˚C and pH 3 to 5 for 30 to 180 minutes, adjusting the pH value of the reaction solution to pH 4.5 to 5.0, and concentrating the rea...
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WO/2008/124821 |
The present invention is directed to analogs of aminoglycoside compounds as well as their preparation and use as prophylactic or therapeutics against microbial infection.
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WO/2008/118784 |
The invention relates to derivatives of glycopeptide and lipoglycopeptide antibiotics possessing one or more polyethylene glycol moieties. These compounds are useful as antibiotics for the prevention and/or the treatment of infections an...
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WO/2008/109121 |
An aqueous, alkaline cleaning composition for use on hard-to-clean soils, encountered in pharmaceutical, personal care, food and cosmetic manufacturing, comprising a source of alkalinity, a biodegradable surfactant system further compris...
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WO/2008/108262 |
The object is to find a novel mechanism of action of ganglioside GD3 on an immune function and a use application of ganglioside GD3 for medical purposes utilizing the mechanism, and to provide a pharmaceutical agent which is effective fo...
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WO/2008/109735 |
Disclosed are inactivators of O6-alkylguanine-DNA alkyltransferase (AGT) having the formula:(I) wherein R, R1 and R3 are as described herein. The inactivators are highly water soluble. Also disclosed are pharmaceutical compositions compr...
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WO/2008/108486 |
The invention provides compounds having excellent cholesterol -lowering effect as well as therapeutic agents, sideration -preventive agents, or evolution-preventive agents for disturbed lipid metabolism, hyperlipidemia, or atherosclerosi...
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WO/2008/108163 |
Disclosed is a novel gadolinium compound having the following characteristic properties (1) to (4): (1) the compound has a high T1-relaxing capability and enables the imaging even when used in a small quantity; (2) the compound is superi...
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WO/2008/108001 |
Disclosed are: a novel monogalactosyldiacylglycerol or digalactosyldiacylglycerol compound or a derivative thereof; a process for production of the compound or the derivative; and a food containing the compound.
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WO/2008/109735 |
Disclosed are inactivators of O6-alkylguanine-DNA alkyltransferase (AGT) having the formula:(I) wherein R, R1 and R3 are as described herein. The inactivators are highly water soluble. Also disclosed are pharmaceutical compositions compr...
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WO/2008/104486 |
The present invention refers to diagnostically or radiotherapeutically useful compounds which are able to selectively bind to lectins, having formula (I) wherein R, R', R1, R2 and R3 are as defined in the specification; the process for t...
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WO/2008/102669 |
Disclosed is a novel sugar-linked chlorin derivative which is useful as a substance for photo-dynamic therapy, is stable, and can act as a photosensitizing substance having high phototoxicity even when used in a small quantity. Also disc...
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WO/2008/099560 |
[PROBLEMS] To provide a simple process by which 5-deoxy-L-arabinose can be efficiently produced. [MEANS FOR SOLVING PROBLEMS] The process includes a step in which a compound represented by the formula (5) is hydrolyzed to obtain an aldos...
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WO/2008/096904 |
Disclosed are: a compound which can impart a high accumulation property in the blood, high stability in the blood and excellent target cell tropism to a substance of interest; a complex of the compound and a substance of interest; and an...
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WO/2008/096239 |
This invention pertains to gaseous analytes sensor devices comprising organic thin film transistor and, in particular, sensors able to perform the enantiomeric discrimination of gaseous analytes. The organic thin films are characterized ...
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WO/2008/096028 |
The present invention provides compounds characterised by the formula (l), where each of the substituent radicals is described in the report. The invention also describes the use of said compounds in the treatment of various diseases, in...
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WO/2008/096880 |
It is intended to develop a method of effectively synthesizing a glycolipid that has never been established so far. Thus, a method for synthesizing a glycolipid is provided. This method comprises the following steps: (a) the step wherein...
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WO/2008/092690 |
The present invention relates to paromamine-based compounds according to formula (I) having selective antimicrobial activity directed at ribosomal 16S RNA. Furthermore, the invention is directed to the use of said compounds for preparing...
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WO/2008/093678 |
[PROBLEMS] To provide: a novel agent having an inhibitory activity on hyaluronidase; and an anti-aging agent for the skin, an anti-inflammatory agent and others each of which comprises the agent. [MEANS FOR SOLVING PROBLEMS] Disclosed is...
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WO/2008/092690 |
The present invention relates to paromamine-based compounds according to formula (I) having selective antimicrobial activity directed at ribosomal 16S RNA. Furthermore, the invention is directed to the use of said compounds for preparing...
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WO/2008/089602 |
The present invention provides aminoside tetracyclic anthraquinones represented by formula I or II, wherein the piptides are introduced to connect tetracyclic anthraquinones and fatty acid saturated or unsaturated in order to make the an...
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WO/2008/088047 |
Disclosed is a method for producing a glycoside of a flavonoid, which comprises the step of reacting the flavonoid and a sugar donor with an enzymatic agent having a glycosylation activity and derived from a bacterium belonging to the ge...
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WO/2008/088806 |
Compounds, compositions and methods for the treatment of HIV/HSP/HPV, in particular, compositions and methods for a 3 part combination therapy for HIV/HSV/HPV, comprising a viral attachment inhibitor, a viral sequence integration inhibit...
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WO/2008/086857 |
5-[4-(2-Methyl-phenyl)-3-hydroxy-4H-[1,2,4]triazol-5-yl]-2,4
-dihydroxy-Λ/- methyl-Λ/-butyl-benzamide is an HSP90 inhibitor and can be used for producing a medicament for treating diseases in which the inhibition, regulation and/or mod...
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WO/2008/089403 |
The invention provides methods for the synthesis of oligosaccharides comprising an aminooxy group. The invention further provides oligosaccharides comprising an aminooxy group, methods for coupling oligosaccharides comprising an aminooxy...
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WO/2008/089403 |
The invention provides methods for the synthesis of oligosaccharides comprising an aminooxy group. The invention further provides oligosaccharides comprising an aminooxy group, methods for coupling oligosaccharides comprising an aminooxy...
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WO/2008/083461 |
There is provided a method of producing a plant composition comprising dehydrosoyasaponin I (D-I), the method comprising the steps of extracting a plant flour with a solvent capable of extracting soyasaponins to produce an extract, and t...
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WO/2008/082156 |
Disclosed are novel α-galactosylceramide derivatives, pharmaceutically acceptable salts thereof, preparation methods thereof, and pharmaceutical compositions for use in an immune adjuvant containing the same as an active ingredient. The...
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WO/2008/078362 |
An antitumor agent containing at least one compound selected from the group consisting of nerigoside, oleandrigenin, sarmentoside, oleaside A, oleandrin, 8β-hydroxy odoroside A, narciclasine, trans-dihydronarciclasine and bisdeoxynarcic...
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WO/2008/075983 |
The invention relates to compounds which are immunomodulatory compounds and, in particular, can induce IL-12 secretion. The invention also relates to compositions containing the compounds, precursors, and prodrugs of these compounds, use...
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WO/2008/075983 |
The invention relates to compounds which are immunomodulatory compounds and, in particular, can induce IL-12 secretion. The invention also relates to compositions containing the compounds, precursors, and prodrugs of these compounds, use...
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WO/2008/075959 |
The present invention is in the field of Fabry disease and concerns a pathogenic factor allowing diagnosis of Fabry disease. In particular lyso-ceramide trihexosamide (lyso-CTH) has been found to function as a diagnostic marker for Fabry...
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WO/2008/071009 |
This application relates to micelle-forming poly(ethylene oxide)-block-poly(ester) block copolymers having reactive groups on both the poly(ethylene oxide) block and the poly(ester) block therein. The biodegradability of these copolymers...
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WO/2008/069303 |
Disclosed is a method for producing a β-anomer of a ribofuranose derivative with high selectivity, in high yield, and in an industrially proper manner. Specifically disclosed is a method for producing a ribofuranose derivative, which is...
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WO/2008/067039 |
Colchicine neoglycosides, method for their synthesis and methods for their use are disclosed. The invention provides analogs of colchicine glycosylated to include a sugar moiety on a colchicine scaffold that is generally unglycosylated i...
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WO/2008/067039 |
Colchicine neoglycosides, method for their synthesis and methods for their use are disclosed. The invention provides analogs of colchicine glycosylated to include a sugar moiety on a colchicine scaffold that is generally unglycosylated i...
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WO/2008/062842 |
Disclosed are a sodium salt represented by the average formula (I) below, and a method for producing such a sodium salt. (In the formula, m1, n1, m2 and n2 independently represent 0 or a positive number not more than 2, while satisfying ...
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WO/2008/060378 |
Compounds and methods are provided for obtaining oligosaccharide mimics. More specifically, compounds and methods are described wherein oligosaccharide mimics are obtained by incorporating or substituting in a cyclohexane derivative.
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WO/2008/060632 |
The invention provides substituted 5'-bi- tri- or tetraphosphate ribose analog compounds that act at P2Y receptors, e.g., the P2Y2 receptor, including pharmaceutical compositions; and uses thereof to treat or prevent diseases associated ...
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WO/2008/060378 |
Compounds and methods are provided for obtaining oligosaccharide mimics. More specifically, compounds and methods are described wherein oligosaccharide mimics are obtained by incorporating or substituting in a cyclohexane derivative.
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WO/2008/059035 |
The present invention relates to a novel process for the chemical synthesis of β-(1->6)-linked glucosamine disaccharides of the fomula (1) and (intermediate) compounds relating to the process. According to further aspects the invention ...
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WO/2008/059035 |
The present invention relates to a novel process for the chemical synthesis of β-(1->6)-linked glucosamine disaccharides of the fomula (1) and (intermediate) compounds relating to the process. According to further aspects the invention ...
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WO/2008/054892 |
A composition and method for the preparation of micro-particles of chitin (a naturally occurring polymer of N-acetyl-D-glucosamine), the characterization of chitin micro-particles as an immune adjuvant and the use of chitin micro-particl...
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