Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 1 - 50 out of 6,397

Document Document Title
WO/2018/167675A1
A process for preparing ketolide compounds is disclosed. (Formula I) (I)  
WO/2018/165250A1
The invention relates to glucuronide prodrug compounds of the Janus kinase (JAK) inhibitor tofacitinib having formula (I): (Formula (I)) where A1 and R1 are as defined. The invention also relates to pharmaceutical compositions comprising...  
WO/2018/161039A1
Lysosomally accumulated substances that release a nitroxy group, or a short chain fatty acid or a product of anaerobic metabolism or a thiol or a sulfide often from an ester or similar labile linkage have anti-inflammatory, anti-cancer a...  
WO/2018/153954A1
The present invention provides immune stimulating macrolide of formula (I). The macrolide has utility in treating viral diseases and cancer.  
WO/2018/153957A1
The present invention provides immune stimulating macrolide of formula (I). The macrolide has utility in treating intracellular bacterial, fungal, and protozoal infections.  
WO/2018/153960A1
The present invention provides immune stimulating macrolides of formula (I), wherein the substituents are as defined in the claims. The macrolides have utility in treating viral diseases and cancer.  
WO/2018/153966A1
The present invention relates to novel compounds useful for visualizing cell sen es c en ce in vitro and in vivo, the preparation of said compounds and their use. In particular, the present invention pertains to novel hexose and particul...  
WO/2018/153959A1
The present invention provides immune stimulating macrolides of formula (I), wherein the substituents are as defined in claim 1. The macrolides have utility in treating intracellular bacterial, fungal, and protozoal infections.  
WO/2018/140594A1
Described herein are prodrugs of cysteamine and pharmaceutically acceptable salts, solvates, and esters thereof. Also described herein are pharmaceutical compositions comprising prodrugs of cysteamine, or pharmaceutically acceptable salt...  
WO/2018/133600A1
Disclosed is a method for preparing high-activity sugarcane anthocyanin. The method comprises: 1) airing and crushing bagasse obtained after juice extraction, and adding distilled water to the bagasse; mixing cellulase, hemicellulase and...  
WO/2018/134412A1
The present invention generally relates to a class of antimicrobial compounds, to compositions containing said compounds and to the use of said compounds for medical and non-medical purposes. More specifically, the present invention rela...  
WO/2018/124695A1
The present invention relates to a novel flavonoid compound separated from a Stauntonia hexaphylla leaf, and a pharmaceutical or food composition, for promoting bone formation or cartilage formation or for preventing, remedying or treati...  
WO/2018/114933A1
The invention relates to novel glycosidase substrates of formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R'9, V, X, Y and Z are as defined in claim 1, and a method for detecting the presence of a catalytically active glycosidase...  
WO/2018/106571A1
Compounds of the Formulae (I) and (II) as described herein, or pharmaceutically acceptable salts thereof, are described, along with pharmaceutical compositions comprising such compounds, salts or combinations thereof, as well as methods ...  
WO/2018/080072A3
The present invention relates to a novel macrolide-based compound, a method for producing the same, and a pharmaceutical composition, which is for preventing or treating malaria and contains the novel macrolide-based compound as an activ...  
WO/2018/080072A2
The present invention relates to a novel macrolide-based compound, a method for producing the same, and a pharmaceutical composition, which is for preventing or treating malaria and contains the novel macrolide-based compound as an activ...  
WO/2018/074794A1
The present specification relates to a novel quercetin-based compound separated from post fermented tea, an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof, the compound being capable of...  
WO/2018/074776A1
The present specification relates to a novel compound separated from post fermented tea, an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof, the compound being capable of being widely us...  
WO/2018/066916A1
The present invention provides a novel Scenedesmus sp. algae, and an extract thereof. This extract of Scenedesmus sp. JD-052, which is a novel Scenedesmus sp. algae, shows a UV protection effect, and thus can be usefully used in the fiel...  
WO/2018/053706A1
A composition comprises a compound of formula (I) and at least one cosmetically acceptable carrier. It can be used for preventing or decreasing skin pigmentation and /or lightening skin tone.  
WO/2018/045294A1
Processes and intermediates for preparing fluoroketolide compounds are described herein.  
WO/2018/039923A1
A preparation method of diosmin, comprising: A) mixing an amide solvent, hesperidin, an alkaline reagent, with iodine, and heating to react to obtain diosmin. Compared with the prior art, the amide solvent used as a reaction solvent has ...  
WO/2018/035410A1
The present invention relates to the discovery that size-expanded DNA nucleotides and analogs thereof inhibit Ροlθ DNA synthesis activity.  
WO/2018/028511A1
Provided are a myricetin derivative, a preparing method and pharmaceutical composition thereof, an application of same in treating colitis, preventing and treating colitis tumorigenesis, and treating colorectal cancer, and a use of same ...  
WO/2018/028511A9
Provided are a myricetin derivative, a preparing method and pharmaceutical composition thereof, an application of same in treating colitis, preventing and treating colitis tumorigenesis, and treating colorectal cancer, and a use of same ...  
WO/2018/021544A1
The present invention provides a 6-acyl-2-O-α-D-glycosyl-L-ascorbic acid represented by general formula (3) (in the formula, n denotes an integer of 1 or higher and R denotes a hydrocarbon group) and/or a composition containing this com...  
WO/2018/021542A1
Provided are a metal salt of 2-O-α-D-glycosyl-L-ascorbic acid represented by general formula (1) (in the formula, n denotes an integer of 1 or higher), an amorphous powder thereof, and a method for producing same. Also provided is an an...  
WO/2018/010170A1
Provided is a novel embodiment of a flavonoid with reduced hygroscopicity and improved storage stability. The flavonoid is applicable for preparing a food, health food, or pharmaceutical product or composition thereof to provide preventi...  
WO/2018/003686A1
[Problem] To provide a fluorescent imaging probe with which it is possible to visualize target cells, such as cells expressing β-galactosidase (lacZ expressing cells), at a single cell level in a selective manner by using a red fluoresc...  
WO/2017/221269A1
The present invention pertains to the enhanced activity of (+) epicatechin over (-) epicatechin. The present invention is related to novel analogs of (+) epicatechin of the formula (I), which enhances the pharmacokinetics and therefore t...  
WO/2017/219509A1
Disclosed are a quinoid chalcone and flavonol conjugate having an anti-tumor activity and an anti-inflammatory activity and a preparation method therefor. Analyses on wave spectrum and mass spectrum data show that a compound (formula I) ...  
WO/2017/210565A1
Compounds of formula (I) or formula (II), compositions and methods useful for treating and/or preventing a fungal infections are provided. wherein the substituents are as defined in the appended claims.  
WO/2017/199028A1
A method of preparing an active agent or a salt thereof from a prodrug first compound (1) comprising a propargyl group connected to an oxygen that is directly or indirectly connected to the active agent is provided, wherein the bond betw...  
WO/2017/194452A1
The present invention relates to seco (opened ring) macrolide compounds of formula (I), to the process for preparation thereof, to the use of said seco macrolide compounds as intermediates for preparation of macrolide based macrocycles, ...  
WO/2017/183972A1
Provided is a particular form of natamycin that shows improved properties as a fungicide for use in agricultural applications. A preferred natamycin composition comprises a structuring agent and a surfactant, Said natamycin composition f...  
WO/2017/177228A1
Provided herein are complexes comprising amphotericin B (AmB) or derivatives and sterols. Also provided herein are methods of treating cystic fibrosis using AmB or complexes comprising AmB or derivatives and sterols.  
WO/2017/173957A1
The present invention relates to the use of a compound of formula (I) below in the control of harmful insects in agricultural and forest crops, wherein R is selected from -CH3 or -C2H5, and the compound is tenvermectin A when R is -CH3 a...  
WO/2017/152273A1
Methods that may be used for the manufacture of a class of chemical compounds known as terpenoid indole alkaloids, including tabersonine and catharanthine are provided. Compositions useful for the synthesis of terpenoid indole alkaloids,...  
WO/2017/151575A1
This invention is based on the discovery that homogeneous catalysts, [Rh(C2H4)2Cl]2 and/or [Rh(COD)2][BF4], can be used to produce spinetoram in higher yields at lower catalyst loadings as compared to previous methodologies. In addition,...  
WO/2017/147624A1
Described are arylnaphthalene lactone derivatives. Also disclosed herein are methods of use of the arylnaphthalene lactone derivatives as anticancer agents.  
WO/2017/142002A1
Provided is, for example, an A-form crystal, etc., of a compound represented by formula [1], which has physical property (a) and/or physical property (b), and has excellent physical properties in environments in which it is produced or u...  
WO/2017/136399A1
The present invention relates to the use of immune regulatory oligonucleotide (IRO) compounds as antagonists of toll-like receptors (TLRs) to inhibit and/or suppress a TLR-mediated immune response induced by endogenous and/or exogenous n...  
WO/2017/124222A1
Disclosed are a method and an intermediate for preparing a tulathromycin. The method comprises the following step: in an organic solvent, subjecting a compound represented by formula (II) and an n-propylamine to a ring-opening addition s...  
WO/2017/124969A1
Provided are a dicaffeoyl-spermidine cyclic derivative and a use. Biological activity tests show that the dicaffeoyl-spermidine cyclic derivative has anti-senile dementia activity and antioxidant activity, the activity of the derivative ...  
WO/2017/121855A1
The present invention relates to compounds of formula (I) These compounds are useful in the treatment of many diseases such as a skin disease, an allergy, an autoimmune disease, a cardiovascular disease, a lung disease, asthma, a bacteri...  
WO/2017/118690A1
The present invention relates to an efficient route of synthesis of solithromycin and to a method of its purification which obviates the necessity of chromatographic purifications and improves the quality of the product by efficiently re...  
WO/2017/100171A1
Compounds of the Formula (I) and (II) as described herein, or pharmaceutically acceptable salts thereof, are described, along with pharmaceutical compositions comprising such compounds, salts or combinations thereof, and methods for maki...  
WO/2017/085329A1
The invention provides novel compounds that are derivatives of Azithromycin and that have been found by the current inventors to have low antimicrobial activity but significant epithelial barrier enhancement properties. The invention fur...  
WO/2017/080313A1
Provided a compound of formula (I): or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and the compound is tetrahydropalmatine deriv...  
WO/2017/080520A1
A method for extracting avermectin B2 from an avermectin ointment comprises: dissolving an avermectin ointment into a crystallizing solvent, separating crystals out by cooling, and performing vacuum filtrating, thus obtaining an avermect...  

Matches 1 - 50 out of 6,397