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Matches 1 - 50 out of 6,343

Document Document Title
WO/2018/003686A1
[Problem] To provide a fluorescent imaging probe with which it is possible to visualize target cells, such as cells expressing β-galactosidase (lacZ expressing cells), at a single cell level in a selective manner by using a red fluoresc...  
WO/2017/221269A1
The present invention pertains to the enhanced activity of (+) epicatechin over (-) epicatechin. The present invention is related to novel analogs of (+) epicatechin of the formula (I), which enhances the pharmacokinetics and therefore t...  
WO/2017/219509A1
Disclosed are a quinoid chalcone and flavonol conjugate having an anti-tumor activity and an anti-inflammatory activity and a preparation method therefor. Analyses on wave spectrum and mass spectrum data show that a compound (formula I) ...  
WO/2017/210565A1
Compounds of formula (I) or formula (II), compositions and methods useful for treating and/or preventing a fungal infections are provided. wherein the substituents are as defined in the appended claims.  
WO/2017/199028A1
A method of preparing an active agent or a salt thereof from a prodrug first compound (1) comprising a propargyl group connected to an oxygen that is directly or indirectly connected to the active agent is provided, wherein the bond betw...  
WO/2017/194452A1
The present invention relates to seco (opened ring) macrolide compounds of formula (I), to the process for preparation thereof, to the use of said seco macrolide compounds as intermediates for preparation of macrolide based macrocycles, ...  
WO/2017/183972A1
Provided is a particular form of natamycin that shows improved properties as a fungicide for use in agricultural applications. A preferred natamycin composition comprises a structuring agent and a surfactant, Said natamycin composition f...  
WO/2017/177228A1
Provided herein are complexes comprising amphotericin B (AmB) or derivatives and sterols. Also provided herein are methods of treating cystic fibrosis using AmB or complexes comprising AmB or derivatives and sterols.  
WO/2017/173957A1
The present invention relates to the use of a compound of formula (I) below in the control of harmful insects in agricultural and forest crops, wherein R is selected from -CH3 or -C2H5, and the compound is tenvermectin A when R is -CH3 a...  
WO/2017/152273A1
Methods that may be used for the manufacture of a class of chemical compounds known as terpenoid indole alkaloids, including tabersonine and catharanthine are provided. Compositions useful for the synthesis of terpenoid indole alkaloids,...  
WO/2017/151575A1
This invention is based on the discovery that homogeneous catalysts, [Rh(C2H4)2Cl]2 and/or [Rh(COD)2][BF4], can be used to produce spinetoram in higher yields at lower catalyst loadings as compared to previous methodologies. In addition,...  
WO/2017/147624A1
Described are arylnaphthalene lactone derivatives. Also disclosed herein are methods of use of the arylnaphthalene lactone derivatives as anticancer agents.  
WO/2017/142002A1
Provided is, for example, an A-form crystal, etc., of a compound represented by formula [1], which has physical property (a) and/or physical property (b), and has excellent physical properties in environments in which it is produced or u...  
WO/2017/136399A1
The present invention relates to the use of immune regulatory oligonucleotide (IRO) compounds as antagonists of toll-like receptors (TLRs) to inhibit and/or suppress a TLR-mediated immune response induced by endogenous and/or exogenous n...  
WO/2017/124222A1
Disclosed are a method and an intermediate for preparing a tulathromycin. The method comprises the following step: in an organic solvent, subjecting a compound represented by formula (II) and an n-propylamine to a ring-opening addition s...  
WO/2017/124969A1
Provided are a dicaffeoyl-spermidine cyclic derivative and a use. Biological activity tests show that the dicaffeoyl-spermidine cyclic derivative has anti-senile dementia activity and antioxidant activity, the activity of the derivative ...  
WO/2017/121855A1
The present invention relates to compounds of formula (I) These compounds are useful in the treatment of many diseases such as a skin disease, an allergy, an autoimmune disease, a cardiovascular disease, a lung disease, asthma, a bacteri...  
WO/2017/118690A1
The present invention relates to an efficient route of synthesis of solithromycin and to a method of its purification which obviates the necessity of chromatographic purifications and improves the quality of the product by efficiently re...  
WO/2017/100171A1
Compounds of the Formula (I) and (II) as described herein, or pharmaceutically acceptable salts thereof, are described, along with pharmaceutical compositions comprising such compounds, salts or combinations thereof, and methods for maki...  
WO/2017/085329A1
The invention provides novel compounds that are derivatives of Azithromycin and that have been found by the current inventors to have low antimicrobial activity but significant epithelial barrier enhancement properties. The invention fur...  
WO/2017/080313A1
Provided a compound of formula (I): or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and the compound is tetrahydropalmatine deriv...  
WO/2017/080520A1
A method for extracting avermectin B2 from an avermectin ointment comprises: dissolving an avermectin ointment into a crystallizing solvent, separating crystals out by cooling, and performing vacuum filtrating, thus obtaining an avermect...  
WO/2017/072295A1
A first aspect of the invention relates to novel compounds and more precisely to novel bifunctional prodrugs and drugs. An additional aspect of the invention relates to antibody compound conjugates, wherein the compound is a claimed comp...  
WO/2017/069565A1
The present invention relates to a method for selectively producing ginsenoside Rd, which is originally present in a trace amount in ginseng, from panaxadiol-based saponins in ginseng and, more specifically, to a method capable of obtain...  
WO/2017/069561A1
The present invention relates to a method for selectively producing ginsenoside F2, compound Mc, and compound O, which is originally present in ginseng in trace amounts, from saponins of ginseng and, more specifically, to a method capabl...  
WO/2017/069569A1
The present invention relates to a method for selectively producing compound K and compound Y, which are originally present in trace amounts in ginseng, from saponins of ginseng and, more specifically, to a method capable of obtaining de...  
WO/2017/057851A1
The present invention relates to a ginsenoside fatty acid ester compound, a method for preparing same, and a cosmetic composition comprising same and, more specifically, to a ginsenoside fatty acid ester compound, modified into a fatty a...  
WO/2017/055502A1
The invention relates to an improved process for the preparation of selamectin of formula 5.  
WO/2017/057460A1
Provided is a method for producing an organic compound, wherein the organic compound is an industrially useful compound, and a deodorization step, for removing from a reaction solution odorants that are generated in or remaining after a ...  
WO/2017/057852A1
The present invention relates to a ginsenoside fatty acid ester compound, a method for preparing same, and a cosmetic composition comprising same and, more specifically, to a ginsenoside fatty acid ester compound, modified into a fatty a...  
WO/2017/057461A1
A production method for producing an aldehyde compound or a ketone compound by oxidizing a primary or secondary alcohol compound, wherein the alcohol compound has, in the molecule thereof, a group selected from an amino group, an azide g...  
WO/2017/058953A1
Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing a nucleic acid.  
WO/2017/050032A1
A ketolide antibiotics intermediate, a preparation method therefor, and application thereof in preparation of solithromycin. The ketolide antibiotics intermediate has a compound structural general formula as shown as follows, and can be ...  
WO/2017/040769A1
Compositions and methods for the production of derivatives of spinosyns are provided. The method produces spinosyn derivatives that exhibit activity towards insects, arachnids, and/or nematodes and are useful in the agricultural and anim...  
WO/2017/040763A1
Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include spinosyn derivatives functionalized on the C5-C6 double bond of th...  
WO/2017/040878A1
Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include those functionalized on the C-13,14 double bond to provide an addi...  
WO/2017/040882A1
Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include spinosyn derivatives functionalized on the C5-C6 double bond of sp...  
WO/2017/028766A1
Disclosed are a method for preparing a taxane derivative of formula 2, and a compound of formula 1 which is used as a raw material or intermediate for preparing the taxane derivative of formula 2.  
WO/2017/013637A1
Provided herein are alpha2-selective Na,K-ATPase inhibitors, characterized by having a cyclic moiety attached to a digoxin or digitoxin derivative, as well as uses thereof in lowering intraocular pressure and in treating glaucoma and hea...  
WO/2017/013648A1
Provided herein are alpha2- selective Na,K-ATPase inhibitors and prodrugs thereof, characterized by having a cyclic moiety attached to a digoxin or digitoxin derivative, as well as uses thereof in lowering intraocular pressure and in tre...  
WO/2016/204493A1
The present invention relates to a novel (1aS,1bS,2S,4S,5aR,6S,6aS)-1a-(hydroxymethyl)-4-methoxy-2-(( (2S,3R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2 H-pyran-2-yl)oxy)octahydrooxireno[2',3':4,5]cyclopenta[1,2-c ]pyran-6-yl 4...  
WO/2016/198485A1
The present invention relates to compounds according to general formula (I) with enhanced absorption of UV-B irradiation. The present invention also relates to an UV-B tolerant plant and a method for enhanced production of compounds acco...  
WO/2016/197980A1
The present invention relates to the technical field of pharmaceutical chemistry, especially to Baicalin crystal form A, and preparation method and application thereof. The crystal form shows characteristic peaks at X-ray powder diffract...  
WO/2016/192829A1
The present invention relates to feed media comprising deep eutectic solvents and/or ionic liquids.  
WO/2016/192830A1
The present invention relates to cell culture media compositions comprising deep eutectic solvents and/or ionic liquids.  
WO/2016/192829A8
The present invention relates to feed media comprising deep eutectic solvents and/or ionic liquids.  
WO/2016/183905A1
An icarisid compound shown in Formula I. The compound is a natural chemical component of a traditional Chinese medicine (epimedium herb) or a chemically modified product or a totally synthetic product based on these natural products. The...  
WO/2016/180818A1
The present invention relates to glycosylating polyphenols via biocatalysis. More specifically the present invention discloses particular mutants of the thermostable sucrose phosphorylase derived from the microorganism Thermoanaerobacter...  
WO/2016/168568A1
Disclosed are derivatives of amphotericin B (AmB) characterized by improved therapeutic index compared to AmB. The AmB derivatives include C16 ureas, carbamates, and amides according to Formula (I); C3' -substituted C16 ureas, carbamates...  
WO/2016/154533A1
The present invention provides desosamine and mycaminose analogs and nitro sugars and methods for their preparation. The invention also provides methods of cyclizing a compound of Formula (Α') with glyoxal to give a nitro sugar of Formu...  

Matches 1 - 50 out of 6,343