| Document |
Document Title |
|
WO/2018/062167A1 |
A method for liberating sugar chains from a glycoprotein, the method including a step in which the glycoprotein is brought into contact with a reactant liquid comprising (a) a hydroxylamine compound and (b) a basic reagent to obtain a li...
|
|
WO/2017/219110A1 |
The present invention discloses a process for obtaining monosaccharides in acid aqueous solution from chitin or chitosan by means of chemical and/or enzymatic hydrolysis. By using low-cost and easily obtainable reagents, this process mak...
|
|
WO/2017/221208A1 |
A mixture of human milk oligosaccharides that comprises or consists essentially of a) LNTri II, LNT, pLNH II and optionally lactose, or b) LNTri II, LNnT, pLNnH and optionally lactose, and is useful for preventing or treating viral or ba...
|
|
WO/2017/187672A1 |
The present invention relates to a method for producing a chitin oligomer (method 1) characterized in that a chitin-containing biomass is partially hydrolyzed while pulverizing using a pulverizer in the presence of water and an acid cata...
|
|
WO/2017/173024A1 |
The present invention is directed to novel products, variants, pharmaceutically acceptable salts and prodrugs thereof, and medical use of such compounds for the treatment and/or management of sepsis, septicemia, septic shock, ocular infe...
|
|
WO/2017/152048A1 |
Aspects of the invention relate to novel synthetic compounds having a binding affinity with galectin proteins.
|
|
WO/2017/101953A1 |
The invention relates to crystalline polymorphs of lacto-N-tetraose (LNT) and methods for making the same for use in pharmaceutical compositions, nutritional formulations and food supplements.
|
|
WO/2017/100618A1 |
This disclosure relates to methods of producing glycans from samples containing glycoconjugates using a salt of a hypohalous acid. Methods for producing N-glycans, O-glycans and lipid linked-glycans are provided. Compositions with novel ...
|
|
WO/2017/100697A1 |
This disclosure relates to specific nanometer-sized nanoparticles made from unmodified dextran (DNPs), DNP conjugates, and related compositions and methods of use.
|
|
WO/2017/085145A1 |
The invention relates to a method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose. This method comprises the chemical reaction of compound of formula (X). Wherein: R1 can be a C1 to C6 alkyl including methyl, ethyl, is...
|
|
WO/2017/085144A1 |
The invention relates to new compounds of formulae: Wherein: R 1 and R 2 can be independently H; a C 1 to C 6 alkyl including methyl, ethyl, propyl, butyl; aryl including phenyl, para-methoxyphenyl; or R 1, R 2 together with the carbon C...
|
|
WO/2017/082753A1 |
The invention relates to novel glycolipid compounds and pharmaceutical compositions comprising said glycolipids and to processes for preparing said glycolipids. The invention also relates to said glycolipids for use in treating tumour...
|
|
WO/2017/075719A1 |
Compositions comprising combinations of chondroitin, glucosamine, connective tissue growth factor (CTGF), transforming growth factor beta 1 (TGFβ1) and WISP-2 are disclosed. Methods, uses and systems relating to the reduction of pain in...
|
|
WO/2017/017509A1 |
The present invention relates to novel oligomers of Neisseria meningitidis serogroup Y capsular polysaccharide repeating unit (Men-Y oligomers) and process for synthesizing novel Men- Y oligomers. In particular, the present invention rel...
|
|
WO/2016/199071A1 |
A mixture of human milk oligosaccharides that consists essentially of 6'-SL, LNnT and LSTc, made by treating 6'-SL and LNnT in the presence of an α2,6-transsialidase.
|
|
WO/2016/164921A1 |
In various embodiments, the invention provides a radiotracer comprising a positron emitting atom bound to a deoxy sugar moiety. The radiotracer is reversible bound to a caging moiety that prevents or retards tissue uptake of the radiotra...
|
|
WO/2015/130890A9 |
The disclosure provides agricultural compositions comprising oligoglucosamine salt complexes and methods for improving plant growth and crop yield. These compositions may be applied to plant propagating materials, including seeds and oth...
|
|
WO/2016/130691A1 |
Disclosed herein is a method for treating heart failure in a subject in need thereof. The method includes administering a therapeutically effective amount of nicotinamide riboside to the subject. The heart failure may be associated with ...
|
|
WO/2016/101211A1 |
The present invention belongs to the technical field of pharmaceutical synthesis, and specially relates to a preparation method for sapropterin hydrochloride. The method comprises glycosylation of L-arabinose, iodination of 5-hydroxy, re...
|
|
WO/2016/084193A1 |
A polymer compound which has a constituent unit derived from a monomer represented by formula (I) and a constituent unit derived from a monomer represented by formula (II) (P2-L2-Y2). A method for producing 6-deoxy-6-radioactive iodo-D-g...
|
|
WO/2016/077388A1 |
A fungicidal compound that includes an aminoglycoside, or salt thereof, having the formula: where R1 is a H; a C1 to C20 branched or straight alkyl; an unsubstituted phenyl; a substituted phenyl, wherein phenyl group may be C1 to C6 alky...
|
|
WO/2016/071485A1 |
The present invention relates to methods of labeling sugar moieties of sugar containing compounds including glycopeptides. The compounds presented in the present invention facilitate reliable detection of sugar moieties of sugar containi...
|
|
WO/2016/070849A1 |
Provided in the present invention are a class of Lincomycin biosynthetic intermediates and a preparation method and use thereof. Specifically provided are Lincomycin biosynthetic intermediates obtained from the genetic modification of a ...
|
|
WO/2016/025790A1 |
Disclosed are UAP inhibitors to inhibit glucose flux in the hexosamine biohynthetic pathway and methods of treating a disease using the inhibitors.
|
|
WO/2016/020635A1 |
There is provided a method for the chlorination of a sucrose-6-acylate to produce a 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose-6-acylate,
wherein said method comprises the following steps (i) to (v): (i) providing a first compone...
|
|
WO/2016/005340A1 |
The present invention relates to hamamelitannin analogues, pharmaceutical compositions comprising the same, and combinations thereof with anti-microbial agents such as antibiotics or disinfectants. It in particular relates to the use of ...
|
|
WO/2015/134256A1 |
Synthetic mixtures comprising two or more synthetic oligoglucosamine based derivatives have been found to be useful in agricultural compositions for promoting seed germination. The disclosed synthetic mixtures may be applied to plant pro...
|
|
WO/2015/130893A1 |
The disclosure provides formulations comprising synthetic oligoglucosamines and methods for improving plant growth and crop yield therewith. These formulations may be applied to propagating materials, including seeds and other regenerabl...
|
|
WO/2015/125782A1 |
A method for producing a compound represented by general formula (II) via a step for reacting a compound represented by general formula (I) with a sulfur compound, and a compound. In general formulas (I) and (II), R1 represents a hydroge...
|
|
WO/2015/127416A1 |
The present invention is directed to a pharmaceutical composition comprising: (1 ) a therapeutically effective quantity of sodium pentosan polysulfate; (2) a quantity of a penetration enhancer sufficient to improve the bioavailability of...
|
|
WO/2015/111627A1 |
The purpose of the present invention is to provide an amino acid precursor capable of improving the properties (especially water solubility, stability in water, bitterness, and the like) of an amino acid and being converted into an amino...
|
|
WO/2015/081297A1 |
Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be admi...
|
|
WO/2015/067640A1 |
The invention relates to an efficient and reproducible process for generating glucosamine from plants which allows high glucosamine content to be obtained while reducing the content of residual ammonium or sulfate ions. The invention als...
|
|
WO/2015/027963A1 |
The present invention relates to an aromatic ring derivative, and pharmaceutical composition and use thereof, in particular to aromatic ring derivatives or hydrates as represented by general formula (II), solvates, stereoisomers thereof,...
|
|
WO/2014/200363A1 |
The invention relates to sphingoglycolipid analogues which are useful in treating or preventing diseases and conditions such as those relating to infection, atopic disorders, autoimmune diseases or cancer.
|
|
WO/2014/196887A1 |
Derived for the first time are individual (without the addition of penta- and hexa-acyl derivatives) di-, tri- and tetra-acyl S-LPS of endotoxic bacteria and combinations thereof, and the immunobiological, physicochemical and chemical...
|
|
WO/2014/187464A1 |
The present application discloses a synthetic mixture of oligosaccharides for treating a microbiota of a mammal, preferably a human, to reduce or eliminate the activity and/or the proportion of a microbe in the microbiota that is associa...
|
|
WO/2014/180264A1 |
The invention relates to a stable organic amine salt of fosphenytoin and the preparation method and use thereof, the related organic amine salt of fosphenytoin having a structure of the general formula as shown in general formula (I), an...
|
|
WO/2014/175838A1 |
A glycopeptide, comprising a polyproline backbone and one or more carbohydrate molecules.
|
|
WO/2014/167538A1 |
This invention relates to achemo-enzymatic synthesis of oligosaccharides of formula 1 I wherein R is selected from -OH, -N 3 and -OR 6 wherein R 6 is selected from allyl optionally substituted by one or more methyl, propargyl optionally ...
|
|
WO/2014/164723A1 |
A new class of molecules, C1-OH tributanoylated hexosamines, including, for example, Ga1NAc, G1cNAc and ManNAc, are demonstrated to increase cartilage-like tissue accumulation by IL- 1β-stimulated chondrocytes. Furthermore, all three mo...
|
|
WO/2014/157635A1 |
The purpose of the present invention is to provide a drug that demonstrates a pharmaceutical effect by having high mobility to the mid-brain and converting to bumetanide in the mid-brain, which is the primary site of epilepsy. The presen...
|
|
WO/2014/154921A1 |
The invention relates to the method for the synthesis of homologous compounds of azanucleosides, to the compounds produced by said method, and to the use of same for developing drugs for treating viral and bacterial diseases and cancer.
|
|
WO/2014/152513A1 |
Disclosed are messenger RNA molecules and related compositions incorporating a 4'-thio modification in the furanose ring of at least one nucleotide residue, and methods of using these mRNAs to produce an encoded therapeutic protein in vi...
|
|
WO/2014/151567A1 |
Described herein are oral care compositions comprising a deoxy sugar antimetabolite and methods of inhibiting microbial biofilm formation and/or degrading a microbial biofilm in a subject.
|
|
WO/2014/132940A1 |
Provided is a method for producing α-halo-tetraacyl glucose, the efficiency of which is excellent and suited to industrial production. The present invention is a method for producing α-halo-tetraacyl glucose represented by general form...
|
|
WO/2014/132468A1 |
Provided is a sugar chain compound as mentioned in item (a) or (b), which contains a 1,2-cis-type sugar residue: (a) a polysaccharide or oligosaccharide formed by repeatedly binding a sugar unit represented by formula (I) or (I'); and (b...
|
|
WO/2014/128660A1 |
The invention relates to methods for making an α-amino-aldehyde, preferably a 2-amino-2-deoxy sugar derivative, from an α-hydroxy-aldehyde, preferably an aldose. Intermediary 1-amino-1-deoxy-ketose derivatives, and their use as synthet...
|
|
WO/2014/094783A1 |
A crystalline LNnT polymorph IV, characterized in that it displays X-ray powder diffraction reflections, based on a measurement using CuKα radiation, at 8.16, 15.41, 39.14, 23.77, 7.77 and 31.15 2Θ angles, and a crystalline LNnT polymo...
|
|
WO/2014/081660A1 |
Inhibitors of sodium glucose cotransporter 1 (SGLT1), compositions comprising them, and methods of their use to treat diseases and disorders such as diabetes are disclosed. Particular compounds are of the formula (I): the various substit...
|
