| Document |
Document Title |
|
WO/2007/125423A2 |
The dimerization of HIV RNA is a key step in the virus replication cycle. Based on RNA DIS crystal structures, a novel kind of compounds, dimeric or not, based on neamine was designed and synthesized. Biological studies showed that such ...
|
|
WO/2007/125543A1 |
An improved process of production of a chlorinated sugar is described comprising chlorination of a partially protected sugar, wherein quenching as well as neutralization of chlorinated reaction mass is carried out concurrently and contin...
|
|
WO/2007/113841A2 |
A new class of paromomycin-derived aminoglycosides (Formula I), which exhibit efficient stop-codon mutation suppression activity, low cytotoxicity and selectivity towards eukaryotic cells are provided. Also provided are processes of prep...
|
|
WO/2007/109561A1 |
Compounds comprising a saccharide molecule and a 5-deoxy-5-methylthio-xylofuranose (MTX) moiety or a 5-deoxy-5-methylsulfoxy-xylofuranose (MSX) moiety, and use of such compounds in methods for modulating inflammation and immune responses.
|
|
WO/2007/104311A1 |
The present invention provides novel lactosamine derivatives and related methods suitable for the preparation, including large-scale production, of N-acetyllactosamine, lactosamine, numerous lactosamine salts and a number of lactosamine-...
|
|
WO2007057920B1 |
A process is described for production of a chlorinated sucrose from a process stream containing a 6-O-protected chlorinated sucrose derived from chlorination of 6-O-protected sucrose wherein the process stream is treated under conditions...
|
|
WO/2007/097643A1 |
This invention relates to compounds that are analogues of coformycin, pharmaceutical compositions containing the compounds, and methods of using the compounds for treating protozoan parasite infections, especially malaria.
|
|
WO/2007/096726A2 |
The present invention relates to an improved, safe, commercially viable, cost effective and eco friendly process for the preparation of 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose (Sucralose). The invention is directed towards the c...
|
|
WO2007052304B1 |
A process of azeotropic removal of dimethylformamide, abbreviated as DMF, from a process stream containing DMF requiring its removal, is described wherein the said Process Stream being .obtained in a process for preparation of 4,1 ', 6' ...
|
|
WO2007054971B1 |
A process is described wherein efficiency of chlorination is improved in a process for production of a chlorinated sucrose by scavenging, using an acid scavenger, of excess of acidic protons formed during a chlorination reaction between ...
|
|
WO2007054973B1 |
A process of production of trichlorogalactosucrose is described in which deacylation of sucrose-6-ester is achieved by subjecting the reaction mixture after chlorination, neutralization and adjustment of pH to 6.5 to 7 to deacylation by ...
|
|
WO/2007/072496A2 |
The present invention relates to a process to prepare sucralose. More particularly the said process relates to the production of sucralose, chemically known as ,6-Dichloro-1,6-dideoxy-ß-D-fructofuranosyl-4-chloro-4-deox
y-alpha-D-galact...
|
|
WO/2007/072208A2 |
An oil product comprises a metal complex polymer solution for its esterification and fermentation reactions. The metal complex polymer is composed of oil, water, R-COOHs soluble saccharide (including sugar-metal) molecules, polymer with ...
|
|
WO/2007/069269A1 |
A process is described for acid mediated deacylation of acyl derivatives of chlorinated sucrose compounds comprising generating a predominantly organic phase condition in a process stream requiring deacylation treatment but allowing an o...
|
|
WO/2007/069923A1 |
The invention relates to compounds of the formula (I), which are L-enantiomeric forms of nucleoside analogues, and to pharmaceutical compositions containing the compounds, methods of treating certain diseases, including cancer, bacterial...
|
|
WO/2007/069924A1 |
The invention relates to compounds of the formula (I), which are L-enantiomeric forms of nucleoside analogues, and to pharmaceutical compositions containing the compounds, methods of treating certain diseases, including cancer, bacterial...
|
|
WO/2007/066567A1 |
[PROBLEMS] To provide a process for production of 18F-TAFDG, which can produce of 18F-TAFDG with a high radioactive fluorination yield. [MEANS FOR SOLVING PROBLEMS] A process for production of a compound labeled with radioactive fluorine...
|
|
WO/2007/063940A1 |
[PROBLEMS] To provide a process for production of 18F-FDG, which can produce of 18F-FDG with a high and steady yield. [MEANS FOR SOLVING PROBLEMS] A process for production of a compound labeled with radioactive fluorine, comprising the s...
|
|
WO/2007/058568A2 |
The invention relates to 1-alkylamino-1-desoxy-polyols and 9-oxoacridine-10-acetic acid salts of general formula (I), wherein A is (II), in which R is selected from an ethyl, propyl and butyl group, to medicinal preparations containing a...
|
|
WO/2007/054977A2 |
The present invention relates to a compound of formula I: [(C)-(L')]n-(A)-[(L)-(B)]mwherein (A) is a thioglycosylated cysteine of formula IIa or IIb: IIa IIb; (B) is a melanogenosis-inhibiting peptide comprising peptide sequence selected...
|
|
WO/2007/052305A2 |
A process is described for extraction of 6- acyl - 4,1’, 6’ trichlorogalactosucrose abbreviated as TGS-6-ester from a process stream containing one or more of TGS-6-ester and impurities including DMF, requiring DMF removal, comprisin...
|
|
WO/2007/052303A2 |
This invention relates to a process for selective capture, isolation and purification of chlorinated sucrose compounds, including chlorinated sucrose, their precursors and derivatives, including trichlorogalactosucrose (TGS), directly fr...
|
|
WO/2007/045192A1 |
Disaccharide synthon I (benzyl-2-acetamido-2-deoxy-β-D-glucopyranosyl-(1→4)-2-ac
etamido-3-0-[1-(R)-carboxyethyl-2-deoxy-α-D-glucopyranoside
) and its use for synthesis of 2-acetamido-2-deoxy-β-D-glucopyranosyl-(1→4)-N-acetylmura
...
|
|
WO/2007/046858A1 |
Disclosed is a process for the preparation of a glucosamine acid addition salt from fructose and ammonia or an ammonia source such as an ammonium compound by contacting fructose and ammonia or an ammonia source in the presence of (i) a s...
|
|
WO/2007/026362A2 |
Methods for preparing cross-linked polysaccharide matrices by cross-linking one or more amino group containing polysaccharides or amino-functionalized polysaccharides with reducing sugars and/or reducing sugar derivatives. The resulting ...
|
|
WO/2007/017891A2 |
A process is described wherein after formation of first crop of Vilsmeier-Haack reagent by reacting Phosphorus Pentachloride with N,N-dimethylformamide to form a first crop of Vilsmeier reagent as insoluble crystals, a by-product of this...
|
|
WO/2007/012695A2 |
The present invention reveals novel methods for producing novel carbohydrate compositions, glycomes, from animal tissues. The tissue substrate materials can be total tissue samples and fractionated tissue parts, or artificial models of t...
|
|
WO/2007/001283A2 |
A process for the synthesis of beta linked low molecular weight polymers of galactosamine and glucosamine has been developed. Through the use of high amounts of activating agents, efficient coupling of stable monomers is achieved. Using ...
|
|
WO/2007/001282A2 |
Compositions containing enriched populations of beta linked low molecular weight polymers of galactosamine and glucosamine are provided. The compositions are useful, for example, as antibacterial additives for food and other edible appli...
|
|
WO/2006/136714A1 |
The invention concerns the use of a compound of general formula (I) wherein: R0 represents in particular a hydrogen atom or an alkyl group; R1 represents in particular a hydrogen atom or an alkyl group; R2, R3 and R4 represent in particu...
|
|
WO/2006/133448A1 |
Described are novel processes for the synthesis triflated sugars. These sugars are useful for the production of compounds, such as D-1-deoxynojirimycin (DNJ) and D-1-deoxygalactonojirimycin (DGJ). In particular, described is a multi- kil...
|
|
WO/2006/127977A1 |
Described herein are fatty acid carbohydrate hybrid compounds and derivatives thereof, and methods of treating or preventing disease and disease symptoms using the compounds and compositions thereof.
|
|
WO/2006/095744A1 |
In a sealable container (1), a first test tube (2) having a sugar chain-containing sample, which has been solidified by drying, and a labeling solution (1a) comprising 2-aminopyridine/acetic cid are enclosed separately from each other. T...
|
|
WO/2006/077397A2 |
The present invention relates to a method of production of a hydrazide modified sugar comprising a step of reacting a sugar with a hydrazide in a reaction solvent at a pH of between 3 and 5.5, wherein the solvent comprises an aqueous bas...
|
|
WO/2006/072965A2 |
An improved process for chlorination is described wherein a solution of chlorinating agent and solution of sucrose-6-ester are mixed together by co- addition to a reaction vessel, the addition of both the reactants starting and completin...
|
|
WO/2006/067366A1 |
The present invention relates to a method for improving stability of non fluoridated sugar derivatives, and in particular glucose derivatives such as 1,3,4,6-tetra-O-acetyl-2-O-trifluoromethanesulfonyl-ß-D-man
nopyranose which are used ...
|
|
WO/2006/057398A1 |
Disclosed is a method for purifying a chitin which includes a step for processing an organic matter containing a chitin in an acidic aqueous solution in the subcritical or supercritical state. Also disclosed is a method for producing a l...
|
|
WO/2006/055644A2 |
The present invention relates to a chemically modified mutant protein including a cysteine residue substituted for a residue other than cysteine n a precursor protein, the substituted cysteine residue being subsequently modified by react...
|
|
WO/2006/037950A1 |
The invention provides a method for the synthesis of an 18F-labelled product comprising deprotected of a protected 18F-labelled compound using a deprotection agent comprising a weak acid and wherein neutralisation and buffering of the de...
|
|
WO/2006/037159A1 |
A method of identifying biologically active compounds with defined selectivity profile comprises: (c) designing a library of compounds of formula (1) to scan molecular diversity; and (d) assaying the library of compounds in at least two ...
|
|
WO/2006/032771A1 |
The invention concerns indolin-2-one derivatives of general formula (I), wherein: R0, R1, R2 and R4 independently of one another represent H, halogen, (C1-C6)alkyl, (C1-C6)alkoxy; R3 represents H, (C1-C6)alkyl; Z represents oxygen, a (C1...
|
|
WO/2006/029453A1 |
A surface active material including an acylated saccharide, processes for the production thereof and uses thereof.
|
|
WO/2006/029452A1 |
The present invention relates to uses of a surface active material including an acylated saccharide. In particular, the invention relates to the use of a surface active material including an acylated saccharide as a surfactant. The acyla...
|
|
WO/2006/021653A2 |
The invention concerns heparanase inhibiting compounds of general formula (I) wherein R represents a hydrogen atom, an hydroxyl radical, a -OSO3- radical, a -O-(C1-C5)alkyl radical or an -O- aralkyl radical; Z represents a COO- radical o...
|
|
WO/2006/016063A1 |
The invention concerns novel glycopolymers, uses thereof, and monomers useful for preparation thereof. The invention also concerns methods for preparing novel monomers and glycopolymers. Thus the invention concerns in particular a polyme...
|
|
WO/2006/016997A2 |
Compounds that are adjuvants and immunoeffectors are described and claimed. The compounds augment antibody production in immunized animals as well as stimulate cytokine production and activate macrophages. Compositions and methods for us...
|
|
WO/2006/012425A2 |
This invention relates to processes for production of alkylamino glucosaminide phosphate compounds, and of disaccharide compounds, including various novel intermediates and intermediate processes. In one aspect, glycosyl halides are prod...
|
|
WO/2005/118607A1 |
Methods of making hyaluronates, including high molecular weight hyaluronates, are disclosed. The methods include contacting a hyaluronate-containing source with an acid to make an acidic hyaluronate suspension, contacting that suspension...
|
|
WO/2005/113568A1 |
The present invention relates to novel galactosides and the use of the galactosides as a medicament, as well as for the manufacture of a medicament for treatment of disorders relating to the binding of galactin to receptors in a mammal. ...
|
|
WO/2005/103063A2 |
The present invention contemplates an apparatus and method for isolating glycoconjugates from mixtures or contaminated mixtures thereof. In the present invention, a bed or other support element comprising a mixture of immobilized lectins...
|
