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Matches 1 - 50 out of 2,142

Document Document Title
WO/2020/191183A1
Targeting ligand clusters, and methods of preparing same, are described. A targeting ligand cluster may include first linkers attached to phenolic hydroxyl groups of gallic acid, and one or more targeting ligands attached to each of the ...  
WO/2020/175440A1
The present invention provides a method for producing a sugar chain, which achieves an excellent yield of a stereocontrolled sugar chain. The present invention also provides building blocks for sugar donors and for sugar acceptors, which...  
WO/2020/163415A1
The invention generally relates to improved processes for the preparation of intermediates of a cyclic dinucleotide which is useful as a STING agonist.  
WO/2020/127417A3
The present invention relates to methods for producing 3-fucosyllactose (3-FL) as well as novel fucosyltransferases, more specifically novel lactose binding alpha-1,3-fucosyltransferase polypeptides, and their applications. Furthermore, ...  
WO/2019/089080A9
Aspects of the invention relate to novel synthetic compounds having a binding affinity with galectin proteins for the treatment of systemic insulin resistance disorders.  
WO/2020/127417A2
The present invention relates to methods for producing 3-fucosyllactose (3-FL) as well as novel fucosyltransferases, more specifically novel lactose binding alpha-1,3-fucosyltransferase polypeptides, and their applications. Furthermore, ...  
WO/2020/090211A1
Provided is a method of adjusting the stability of double-stranded RNA, the method comprising (1) a step of introducing a modification into the backbone of double-stranded RNA; and (2) a step of bringing the double-stranded RNA provided ...  
WO/2020/040071A1
[Problem] To provide a method for decomposing chondroitin sulfate contained in a sample into disaccharides. [Solution] A method which comprises heating chondroitin sulfate contained in a sample at a temperature of 60-90°C for 50-180 min...  
WO/2020/014386A1
The present disclosure provides compositions and methods for the treatment of cancer. Specifically, the compositions of the present technology include novel clearing agents that may be used in pretargeted radioimmunotherapy.  
WO/2019/236327A1
Described herein are sulfur-containing glycosaminoglycans, and methods of making and using them. For example, heparosan and hyaluronan analogs are described which incorporate one or more sulfur-containing sugar units that include one or ...  
WO/2019/215164A1
The present invention relates to a composite friction lining material comprising a friction mix and a binder resin, wherein the binder resin comprises a carbohydrate based binder resin, the carbohydrate based binder resin being obtained ...  
WO/2019/179325A1
The present invention relates to the field of carbohydrate chemistry, and discloses a preparation method for a surface capsular polysaccharide structural derivative of Gram-positive bacteria. In the present invention, glucose is used as ...  
WO/2019/172836A1
A protein-binding product comprising one or more porous polymer beads, wherein at least one ligand is bound to the surfaces of said polymer beads via a spacer (R), and wherein said at least one ligand is Galβ1-3Hex NAcβ-O-, Galβ1-4Glc...  
WO/2019/144842A1
The present invention relates to a thiazole-5-formic acid derivative, a stereoisomer and a pharmaceutically acceptable salt thereof, the structure of the thiazole-5-formic acid derivative being represented by general formula (I). The com...  
WO/2019/145562A1
The present invention relates to anew class of sialyltransferase inhibitors. The class features a carbamate or similar moiety on the amine of a neuraminic acid derivative. Such inhibitors are suitable for use as a medicament, for example...  
WO/2019/118829A3
Provided herein, inter alia, are methods, bacteria, nucleic acids, and polypeptides for producing sialylated oligosaccharides.  
WO/2019/140147A1
Methods for identifying or monitoring or treating HIV persistence or the development of an HIV-comorbidity in an HIV+ subject involve certain selected glycan dysregulations. In certain embodiments, hyposialylation in the total IgG glycom...  
WO/2019/121739A1
The present invention relates to a water-soluble binder composition comprising at least one carbohydrate component and at least one carbon dioxide reaction product comprising at least the reaction product(s) of carbon dioxide with at lea...  
WO/2019/115616A1
The present invention relates to Novel 1,7-dicarba-closo- dodecaborane(12) (meta-carbaborane)-derived carboxylic acids suitable for peptide modification for application in boron neutron capture therapy (BNCT).  
WO/2019/115617A1
The present invention relates to Novel 1,7-dicarba-closo-dodecaborane (meta-carbaborane)-derived carboxylic acids and amines according to Formula (I) suitable for peptide modification for application in boron neutron capture therapy (BNC...  
WO/2019/112112A1
The present invention relates to a method for extracting a wasabi extract, the method being characterized in that: 53-61 part by weight of a wasabi powder and 25-30 parts by weight of pure scotch whisky are mixed to produce a wasabi extr...  
WO/2019/090802A1
Disclosed are a diglycosylated benzophenoxazine photosensitizer and a preparation method and the use thereof. The present invention greatly improves the enriched concentration of the photosensitizer in tumor cells by taking full advantag...  
WO/2019/089080A1
Aspects of the invention relate to novel synthetic compounds having a binding affinity with galectin proteins for the treatment of systemic insulin resistance disorders.  
WO/2019/087810A1
The present invention is capable of producing a 1,3,4,6-tetra-O-acyl-2-deoxy-2-fluoroglucose in high yield by reacting a 1,3,4,6-tetra-O-acyl-2-O-(trifluoromethylsulfonyl)-β-D­man opyranose with hydrogen fluoride in the presence of a s...  
WO/2018/053135A9
The present disclosure provides a novel sweetener composition of improved taste of the sweetener (e.g., reduced bitterness and/or astringency, and improved overall sweet quality of the composition); food and beverage products containing ...  
WO/2019/068726A1
The present invention relates to a cellular transport system for bringing a sulfonic acid construct which carries a cargo into a cell and releasing the cargo in the cell's cytoplasm, the cellular transport system comprising: (i) a sulfon...  
WO/2019/002594A1
The present invention discloses a method for separating chromatographically indistinguishable 1,2-diaxial from 1,2- diequatorial disaccharide 2-azido-1-nitrates, wherein the disaccharide is a 1→4 disaccharide, comprising the steps of -...  
WO/2018/209276A1
Aspects of the invention relate to novel synthetic compounds for treatment of metabolic diseases partially associated with systemic insulin resistance caused by Galectin proteins binding and inhibiting insulin and TGFb1 receptors causing...  
WO/2018/187740A1
Cyclooctene conjugates of therapeutic or diagnostic agents have improved aqueous solubility and can release the agents upon contact with a tetrazine-containing biomaterial. The cyclooctene conjugates provide site-selective delivery of ag...  
WO/2018/002957A3
The present invention relates to a process for synthesis of 6-Deoxy-L-Hexoses from L-Rhamnose comprising the steps of optional regioselective protection of C2-, C3- and/or C4-OH of the L- Rhamnose of formula (1) to obtain compounds of fo...  
WO/2018/167794A1
Synthetic pathways for preparing pseudo-trisaccharide aminoglycoside compounds represented by Formula I or Ia as defined in the specification and donor and acceptor compounds useful for preparing such compounds are provided. A process of...  
WO/2017/219110A8
The present invention discloses a process for obtaining monosaccharides in acid aqueous solution from chitin or chitosan by means of chemical and/or enzymatic hydrolysis. By using low-cost and easily obtainable reagents, this process mak...  
WO/2018/083490A3
There is provided a molecule comprising a chain of seven or more contiguous units of 4,6-dideoxy-4-acylamido-α-pyranose, each pair of units joined by a C1-C2 or a C1-C3 link, the chain having a terminal end and a reducing end, wherein t...  
WO/2018/139599A1
Disclosed are: a compound represented by general formula (I), a pharmaceutically acceptable salt thereof or a solvate of the same; a medicinal composition comprising the same; use of the same for preventing or treating infectious disease...  
WO/2018/140594A1
Described herein are prodrugs of cysteamine and pharmaceutically acceptable salts, solvates, and esters thereof. Also described herein are pharmaceutical compositions comprising prodrugs of cysteamine, or pharmaceutically acceptable salt...  
WO/2018/100549A1
The present invention refers to exopolysaccharide molecules, conditioned media or compositions comprising said molecules or media. Moreover, the present invention refers to use of said exopolysaccharide molecules, conditioned media or co...  
WO/2018/100561A1
The present invention relates to mononuclear coordination compounds of Au and Cu, pharmaceutical formulations based thereof, the relative method of synthesis and encapsulation of the compounds in macromolecules, supramolecular aggregates...  
WO/2018/083490A2
There is provided a molecule comprising a chain of seven or more contiguous units of 4,6-dideoxy-4-acylamido-α-pyranose, each pair of units joined by a C1-C2 or a C1-C3 link, the chain having a terminal end and a reducing end, wherein t...  
WO/2018/067900A1
Provided herein are solid phase methods for the synthesis of conjugated oligomeric compounds and intermediates used in such methods. In particular, the solid phase methods provide for addition of a phosphoramidite functionalized conjugat...  
WO/2018/058723A1
Provided are a method for enzymatic synthesis of a sialic acid analogue: with sialic acid aldolase as a catalyst, subjecting a substrate containing an aldehyde group to a condensation reaction with a substrate containing a carbonyl group...  
WO/2018/062167A1
A method for liberating sugar chains from a glycoprotein, the method including a step in which the glycoprotein is brought into contact with a reactant liquid comprising (a) a hydroxylamine compound and (b) a basic reagent to obtain a li...  
WO/2018/053135A1
The present disclosure provides a novel sweetener composition of improved taste of the sweetener (e.g., reduced bitterness and/or astringency, and improved overall sweet quality of the composition); food and beverage products containing ...  
WO/2018/013466A3
The present invention is based on the identification of novel biomarkers predictive of endocrine resistance in breast cancer.  
WO/2017/219110A1
The present invention discloses a process for obtaining monosaccharides in acid aqueous solution from chitin or chitosan by means of chemical and/or enzymatic hydrolysis. By using low-cost and easily obtainable reagents, this process mak...  
WO/2017/221208A1
A mixture of human milk oligosaccharides that comprises or consists essentially of a) LNTri II, LNT, pLNH II and optionally lactose, or b) LNTri II, LNnT, pLNnH and optionally lactose, and is useful for preventing or treating viral or ba...  
WO/2017/187672A1
The present invention relates to a method for producing a chitin oligomer (method 1) characterized in that a chitin-containing biomass is partially hydrolyzed while pulverizing using a pulverizer in the presence of water and an acid cata...  
WO/2017/173024A1
The present invention is directed to novel products, variants, pharmaceutically acceptable salts and prodrugs thereof, and medical use of such compounds for the treatment and/or management of sepsis, septicemia, septic shock, ocular infe...  
WO/2017/152048A1
Aspects of the invention relate to novel synthetic compounds having a binding affinity with galectin proteins.  
WO/2017/101953A1
The invention relates to crystalline polymorphs of lacto-N-tetraose (LNT) and methods for making the same for use in pharmaceutical compositions, nutritional formulations and food supplements.  
WO/2017/100618A1
This disclosure relates to methods of producing glycans from samples containing glycoconjugates using a salt of a hypohalous acid. Methods for producing N-glycans, O-glycans and lipid linked-glycans are provided. Compositions with novel ...  

Matches 1 - 50 out of 2,142