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WO/2014/094544A1 |
Provided are a phenyl C-glucoside derivative containing a deoxyglucose structure as represented by formula I, preparation method thereof, pharmaceutical composition containing same, and uses thereof in the preparation of drugs for treati...
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WO/2014/067003A1 |
The invention provides compounds with enhanced permeability for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also prov...
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WO/2014/013181A1 |
The invention relates to a thiophene derivative of the following general formula (I) or an enantiomer, diastereoisomer, hydrate, solvate, tautomer, racemic mixture or pharmaceutically acceptable salt thereof, and the use of same as a med...
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WO/2013/178064A1 |
Disclosed are a substituted pyranol derivative with sodium dependent glucose transporters (SGLTs) inhibitor compound 4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl, a preparation method thereof, and a pharmaceutical application thereof; and p...
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WO/2013/172239A1 |
The present invention is an acid diffusion control agent consisting of at least one compound selected from among the group consisting of a compound represented by formula (1) and a compound represented by formula (2). In formula (1), R2 ...
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WO/2013/152359A1 |
Provided herein, inter alia, are compositions and methods of synthesis and detection of tetrazines and diazonorcaradienes.
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WO/2013/133419A1 |
[Problem] To provide a novel gelling agent that includes a sugar derivative. [Solution] A gelling agent comprising a compound represented by formula (1) or (2) (wherein R1 and R3 each independently represent a C1-20 straight-chain or bra...
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WO/2013/123896A1 |
Provided is a method for preparing 3-O-benzyl-1,2-O-isopropylidene-α-L-furan idose, which comprises: (1) protecting hydroxyl of 3-O-benzyl-1,2-O-isopropylidene-α-D-glucofuranose (III) by benzoyl and methylsulfonyl to obtain 6-O-benzoyl...
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WO/2013/097042A1 |
Disclosed is a compound of formula 1, as shown below, where R1, R2, R3, R4, R5, R6 and R7 are as described herein. Also, disclosed is a process for the preparation of compounds of formula 1, and intermediates used therein. The compound o...
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WO/2013/046180A1 |
A method that can be used to make a precursor of L-fiicose from D-glucose, that comprises the steps of: a) making a compound of formula (1) from D-glucose, formula (1) wherein R1 is acyloxy, and Q is a group (a), (b), (c) or (d), Formula...
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WO/2013/004626A1 |
The present invention is concerned with a process for preparing acetals and ketals which comprises (i) reacting an aldehyde or ketone with an alcohol in the presence of a solid acid at a temperature of below -40 °C, and (ii) removing wa...
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WO/2013/000086A1 |
The invention provides compounds for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating di...
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WO/2013/000084A1 |
The invention provides compounds with enhanced permeability for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also prov...
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WO/2012/129651A1 |
The invention provides compounds of formula (I) with substituents as specified in claim 1 for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceuticals compositions including the compounds or prodrugs of the com...
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WO/2012/126091A1 |
The invention provides compounds for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating di...
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WO/2012/083435A1 |
The invention provides compounds with enhanced permeability for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also prov...
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WO/2012/061927A1 |
The invention provides compounds for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating di...
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WO/2012/008228A1 |
Disclosed is a method for oxidizing alcohols, wherein it is possible to efficiently oxidize primary alcohols and secondary alcohols and to achieve high reaction efficiency even when air is used as the bulk oxidant. Specifically disclosed...
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WO/2011/098460A1 |
The invention relates to a method for generating three-dimensional self-supporting and/or substrate-supported molded bodies or structures on surfaces by solidifying a liquid to paste-like organic or organically modified material in selec...
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WO/2011/096934A1 |
A process for the preparation of topiramate in an one pot reaction comprises the following steps: A) reacting 2,3:4, 5 -bis -O- { 1-methylethylidene) -β-D-f ructopyranose with sulfurylchloride in xylene in the presence of an organic or ...
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WO/2011/021398A1 |
Provided are pyranose derivatives and furanose derivatives, depicted in formulas (I) through (V), of glucose, mannose, psicose, sorbose, tagatose, allose, altrose, gulose, idose, or talose. (In the formulas, M1 represents a specific poly...
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WO/2010/150789A1 |
Disclosed is a novel production method for efficiently and easily synthesizing an NC-type nucleoside at a high yield without requiring a step for converting an unnecessary protecting group. Specifically disclosed are a step for inverting...
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WO2010110382A1 |
Disclosed is a novel compound contained in blue rose. This novel compound, which is contained in blue rose, has a chemical structure represented by general formula (I) [wherein R1 is a group as set forth in claim 1; and R2 represents -OH...
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WO/2010/103857A1 |
Disclosed are a novel method for the synthesis of a glycopeptide by which glycopeptides of various types can be deprotected and excised from a resin, each under weakly acidic to weakly basic conditions, without causing the problems of th...
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WO/2009/102022A1 |
Provided is a 3,6-O-bridged pyranose inversion compound useful as a β-O-glycosylating agent for use in selectively and easily producing β-O-pyranoside. The 3,6-O-bridged pyranose inversion compound is represented by general formula (1)...
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WO/2009/014970A1 |
Methods of synthesizing sodium glucose co-transporter 2 inhibitors, as well as compounds useful therein, are disclosed. Particular inhibitors are compounds of formula (I).
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WO/2008/152386A1 |
The invention relates to a process for preparing furanose derivatives, to furanose intermediates used in said process and to the use of said derivatives in the manufacture of atorvastatin.
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WO/2008/148549A2 |
The invention relates to a process for the catalytic conversion of a carbohydrate, an alcohol, an aldehyde or a polyhydroxy compound in the presence of a catalyst containing gold in a solvent.
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WO/2008/111526A1 |
Disclosed is a method for producing an oxazoline derivative from a non-protected sugar in a simple manner. Also disclosed is a method for producing a glycoside by utilizing the product of the aforementioned method. A sugar oxazoline deri...
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WO/2008/096880A1 |
It is intended to develop a method of effectively synthesizing a glycolipid that has never been established so far. Thus, a method for synthesizing a glycolipid is provided. This method comprises the following steps: (a) the step wherein...
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WO/2008/068413A2 |
The invention relates to a method for preparing acetyl,docosahexaenoyl-glycerophosphocholine (AcedoPC) and to the use thereof for the delivery of DHA and Neuroprotectin D1.
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WO/2007/108009A1 |
The present invention provides novel process for the preparation of Topiramate Form I which comprising purifying crude Topiramate base by treating the same with mixture of acetone and water to obtain topiramate of at least 99.5% purity.
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WO/2007/099388A1 |
An improved process for the manufacture of 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate, viz. Topiramate is reported. It consists of subjecting an intermediate of the formula 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fr...
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WO/2007/093769A1 |
This invention provides a method for inhibiting oligosaccharide biosynthesis in vivo and in vitro comprising the steps of administering at least one monosaccharide derivative, wherein the hydroxyl group which is the glycosyl acceptor (i....
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WO/2006/111783A1 |
The present invention relates to monosaccharide derivatives as anti-inflammatory agents. The compounds disorder herein can be useful for inhibition and prevention of inflammation and associated pathologies including inflammatory and auto...
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WO2005092907B1 |
The present invention relates to monosaccharide derivatives as anti-inflammatory agents. The compounds disorder herein can be useful for inhibition and prevention of inflammation and associated pathologies including inflammatory and auto...
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WO/2005/100373A2 |
The present invention relates to monosaccharide derivatives as anti-inflammatory agents. The compounds disclosed herein can be useful for inhibition and prevention of inflammation and associated pathologies, including inflammatory and au...
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WO/2005/062748A2 |
Bicyclic carbohydrates for the treatment of infections caused by herpseviridae, and in particular cytomegalovirus. The invention consists of the novel bicyclic carbohydrates the generic structure of which is formula I: wherein R1 is eith...
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WO/2005/016514A2 |
Methods are disclosed for providing a library of composite or novel composition samples on a support. The method involves depositing one or more components as concentration gradients on the surface of the support. The concentration gradi...
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WO/2004/104163A2 |
A method of &agr -selective glycosylation comprising forming a cyclic protective group having a silyl acetal structure over hydroxyl groups at the 4- and 6-positions in a hexose or higher saccharide structure, which is a monosaccharide o...
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WO/2004/099229A1 |
The present invention relates to processes for the synthesis of base addition salts of particular ß-L- gulofuranosides. More specifically, the invention relates to synthetic processes for making base addition salts of 2,3-O-isopropylide...
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WO/2004/089965A2 |
A process of preparing topiramate of the Formula (I) which comprises the following reaction steps and topiramate prepared thereby, compositions containing the same, therapeutic uses thereof and methods of treatment employing the same.
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WO/2004/078769A1 |
The present invention is directed to a one-step process for the preparation of fructopyranose sulfamate derivatives of general formula (I), wherein X, R1, R3, R4, R5 and R6 are as described in the specification.
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WO/2004/075843A2 |
It is taught here that enkephalin peptides which are glycosylated with a disaccharide will be transported across the blood brain barrier and deliver analgesic effects superior to morphine when introduced into the bloodstream. Glycosylate...
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WO/2004/074303A2 |
The present invention provides methods for preparing LPS antagonist lipodisaccharide B1287 and stereoisomers thereof, which compounds are useful as in the prophylactic and affirmative treatment of endotoxemia including sepsis, septicemia...
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WO/2004/063210A1 |
The invention relates to novel pharmaceutically acceptable salts of anticonvulsant derivatives, processes for preparation of and pharmaceutical compositions containing said salts, useful in the treatment of epilepsy.
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WO/2004/050676A1 |
A method in which a glucide, examples of which include a monosaccharide, an oligosaccharide, a polysaccharide, a composite saccharide comprising any of these saccharides and a protein or lipid bonded thereto, a polyalcohol, an aldehyde, ...
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WO/2004/041836A1 |
The present invention is directed to a continuous process for the preparation of fructopyranose sulfamate derivatives of the general formula (I) wherein R1, R3, R4, R5, R6 and X are as herein defined. The present invention is further dir...
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WO/2004/034960A2 |
The present invention relates to pentose and pentose derivatives that are effective at increasing glucose transport in a non-insulin dependent manner, and to uses thereof for a) treating and/or preventing hyperglycemia; b) treating and/o...
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WO/2004/032625A2 |
This invention relates to devices, kits, and methods for eliminating termite colonies. The kits, devices, and methods employ a termiticidal bait matrix containing a) a termiticide selected such that the termiticide causes death to about ...
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